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ORBIT
MCID: ORB013
MIFTS: 42

Orbital Disease (ORBIT)

Categories: Bone diseases, Eye diseases, Muscle diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Orbital Disease

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MalaCards integrated aliases for Orbital Disease:

Name: Orbital Disease 12 15
Orbital Diseases 44
Orbit 71

Classifications:

MalaCards categories:
Anatomical: Eye diseases Bone diseases Muscle diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:930
ICD9CM 34 376.9
MeSH 44 D009916
SNOMED-CT 67 267746003
UMLS 71 C0029182
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Summaries for Orbital Disease

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Disease Ontology : 12 An adnexa disease that is located in the eye socket.

MalaCards based summary : Orbital Disease, also known as orbital diseases, is related to exophthalmos and orbital cancer, and has symptoms including visual disturbance and eye manifestations. An important gene associated with Orbital Disease is ERCC6 (ERCC Excision Repair 6, Chromatin Remodeling Factor), and among its related pathways/superpathways is Thyroxine (Thyroid Hormone) Production. The drugs Acetylcholine and Atracurium have been mentioned in the context of this disorder. Affiliated tissues include eye socket, eye and thyroid, and related phenotypes are hematopoietic system and immune system

Wikipedia : 74 In anatomy, the orbit is the cavity or socket of the skull in which the eye and its appendages are... more...

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Related Diseases for Orbital Disease

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Diseases related to Orbital Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 334)
# Related Disease Score Top Affiliating Genes
1 exophthalmos 30.5 TSHR TG PRTN3 NF1
2 orbital cancer 30.0 PRTN3 NF1
3 eye disease 29.9 TSHR MIR193A ERCC6 CRYAA CD4
4 acute dacryoadenitis 29.9 CRP ACE
5 ocular motility disease 29.9 PHOX2A KIF21A CRYAA
6 endocrine exophthalmos 29.8 TG CD5
7 orbital cellulitis 29.7 CRYAA CRP CD4
8 papilledema 29.6 CRP CD4 ACE
9 optic nerve disease 29.6 NF1 ERCC6 CRYAA CRP CD4 ACE
10 graves' disease 29.5 TSHR TG IL16 CTLA4
11 hyperthyroidism 29.5 TSHR TG PRTN3 CTLA4 CRP
12 scleritis 29.5 PRTN3 CTLA4 CRP
13 strabismus 29.5 TSHR PHOX2A NF1 KIF21A CRYAA
14 keratitis, hereditary 29.4 PHOX2A KIF21A CRYAA CD4
15 granulomatosis with polyangiitis 29.4 PRTN3 CTLA4 CRP CD4
16 myxedema 29.3 TSHR TG CTLA4
17 orbital plasma cell granuloma 29.3 TSHR PRTN3 CTLA4 CRP
18 thyroiditis 29.2 TSHR TG CTLA4 CRP
19 enophthalmos 29.0 SLC39A13 PHOX2A NF1 FBN1 ERCC6 EPB41L1
20 hashimoto thyroiditis 28.7 TSHR TG CTLA4
21 hypothyroidism 28.6 TSHR TG CTLA4 CRP ACE
22 purulent acute otitis media 10.4 PRTN3 CRP
23 frontal sinusitis 10.4 PRTN3 CRP
24 bicipital tenosynovitis 10.4 PRTN3 CRP
25 ethmoid sinusitis 10.4 PRTN3 CRP
26 subclavian artery aneurysm 10.4 NF1 CRP
27 hemopericardium 10.3 FBN1 CRP
28 interstitial keratitis 10.3 CRYAA CRP
29 subungual glomus tumor 10.3 NF1 CRP
30 iodine hypothyroidism 10.3 TSHR TG
31 myotonic cataract 10.3 PHOX2A KIF21A
32 facial hemiatrophy 10.3 KIF21A CRP
33 marcus gunn phenomenon 10.3 PHOX2A KIF21A
34 thyroid crisis 10.3 TSHR TG
35 toxic diffuse goiter 10.3 TSHR TG
36 postsurgical hypothyroidism 10.3 TSHR TG
37 branch retinal artery occlusion 10.3 PRTN3 CRYAA CRP
38 fibrosis of extraocular muscles, congenital, 2 10.3 PHOX2A KIF21A
39 dacryocystocele 10.3 PRTN3 NF1
40 athyreosis 10.3 TSHR TG
41 central retinal artery occlusion 10.3 PRTN3 CRYAA CRP
42 chronic inflammation of lacrimal passage 10.3 PRTN3 NF1
43 pulmonary aspergilloma 10.3 TG CRP
44 paralytic squint 10.3 PHOX2A KIF21A
45 subacute bacterial endocarditis 10.3 PRTN3 CRP
46 mastoiditis 10.3 PRTN3 CRP
47 lens disease 10.3 FBN1 ERCC6 CRYAA
48 cogan syndrome 10.3 PRTN3 CRP
49 tracheal disease 10.3 PRTN3 FBN1 CRP
50 microphthalmia, isolated 5 10.3 PHOX2A KIF21A

Graphical network of the top 20 diseases related to Orbital Disease:



Diseases related to Orbital Disease
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Symptoms & Phenotypes for Orbital Disease

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UMLS symptoms related to Orbital Disease:


visual disturbance, eye manifestations

MGI Mouse Phenotypes related to Orbital Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 ACE CD4 CD5 CTLA4 ERCC6 FBN1
2 immune system MP:0005387 9.73 ACE CD4 CD5 CRP CTLA4 ERCC6
3 nervous system MP:0003631 9.36 ACE CD4 CD5 EPB41L1 ERCC6 FBN1
Sources

Drugs & Therapeutics for Orbital Disease

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Drugs for Orbital Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 200)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2
Atracurium Approved, Experimental, Investigational Phase 4 64228-79-1 47319
3
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
4
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
5
Pancrelipase Approved, Investigational Phase 4 53608-75-6
6
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
7 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
8
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
9
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
10
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
11
Cocaine Approved, Illicit Phase 4 50-36-2 5760 446220
12
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
13
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
14
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
15 Neurotransmitter Agents Phase 4
16 abobotulinumtoxinA Phase 4
17 Botulinum Toxins, Type A Phase 4
18 Botulinum Toxins Phase 4
19 Cholinergic Agents Phase 4
20 Neuromuscular Blocking Agents Phase 4
21 Cholinergic Antagonists Phase 4
22 Neuromuscular Nondepolarizing Agents Phase 4
23 Anesthetics Phase 4
24 Pharmaceutical Solutions Phase 4
25 Anesthetics, Local Phase 4
26 Sodium Channel Blockers Phase 4
27 Diuretics, Potassium Sparing Phase 4
28 Anti-Arrhythmia Agents Phase 4
29 Analgesics Phase 4
30 pancreatin Phase 4
31 Liver Extracts Phase 4
32 Chelating Agents Phase 4
33 Gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate Phase 4
34 Hormones Phase 4
35 Protective Agents Phase 4
36 Gastrointestinal Agents Phase 4
37 Anti-Inflammatory Agents Phase 4
38 Methylprednisolone Acetate Phase 4
39 Hormone Antagonists Phase 4
40 Neuroprotective Agents Phase 4
41 glucocorticoids Phase 4
42 Antineoplastic Agents, Hormonal Phase 4
43 Antiemetics Phase 4
44 Antibiotics, Antitubercular Phase 4
45 Anti-Bacterial Agents Phase 4
46 Anti-Infective Agents Phase 4
47 beta-Lactamase Inhibitors Phase 4
48
Ciprofloxacin Approved, Investigational Phase 3 85721-33-1 2764
49
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
50
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3

Interventional clinical trials:

(show top 50) (show all 178)
# Name Status NCT ID Phase Drugs
1 Combined Radiotherapy and Intravenous Steroids for Early Progressive Thyroid Eye Disease Unknown status NCT02339142 Phase 4 intravenous corticosteroids (methylprednisolone)
2 The Effect of "Eye Drop Guide" on the Success Rate of Eye Drops Self-instillation in Glaucoma Patients. Unknown status NCT01704248 Phase 4
3 A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at National Eye Centre, Kaduna. Nigeria Completed NCT02150460 Phase 4
4 A Double Blinded Randomized Controlled Trial to Compare the Efficacy, Time to Onset, and Duration of Two Botulinum Type A Exotoxins (Onabotulinum Toxin A and Abobotulinum Toxin A) in the Treatment of "Crow's Feet." Completed NCT01529788 Phase 4 Right lateral orbital injection of Botox Cosmetic or Dysport;Left lateral orbital injection of Botox Cosmetic or Dysport
5 Ablative Fractional Lasers (CO2 and Er:YAG): A Randomized Controlled Blinded Split-face Trial of the Treatment of Peri-orbital Rhytides Completed NCT00990431 Phase 4
6 Comparison of Clinical Outcome Parameters, the Patient Benefit Index (PBI) and Patient Satisfaction After Ablative Fractional Laser Treatment of Peri-orbital Rhytides Completed NCT00994474 Phase 4
7 Efficacy and Safety of Low Dose Atracurium Added to Lidocaine, Bupivacaine and Hyaluronidase Mixture in Percaruncular Peribulbar Anesthesia for High Myopes Undergoing Phacoemulsification: A Randomized Controlled Trial. Completed NCT03243500 Phase 4 Atracurium;Lidocaine 2%;Bupivacaine 0.5%;hyaluronidase powder
8 Postoperative Pain Control After Enucleation or Evisceration, a Double-Masked Randomized Controlled Trial of Standard Versus Slow-release Bupivacaine Recruiting NCT02381353 Phase 4 Bupivacaine
9 Comparison of Great Occipital Nerve and Supraorbital Nerve Blockade Treatment Methods Individually and in Combination With Placebo in an Acute Migraine Attack in the Emergency Department, a Prospective, Double Blind, Randomized Controlled Study Recruiting NCT04491474 Phase 4 Lidocaine Hydrochloride;Placebo
10 Evaluation of Gadoterate in Patients With Renal Dysfunction Active, not recruiting NCT02382380 Phase 4 Gadoterate
11 VISmodegib for ORbital and Periocular Basal Cell Carcinoma (VISORB) Active, not recruiting NCT02436408 Phase 4 Vismodegib
12 A Phase IV, Randomized, Multi-center Clinical Trial to Compare the Efficacy of Orbital Radiotherapy in Association With Intravenous Glucocorticoids vs Intravenous Glucocorticoids Alone for Moderately Severe and Active Graves' Orbitopathy Not yet recruiting NCT03098225 Phase 4 Methylprednisolone
13 Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures (Mandibular Fractures, Zygomaticoorbital Fractures, Isolated Orbital Blow-out Fractures and LeFort I/II/III Fractures): 1 Day vs. 5 Days: a Prospective, Randomized, Double Blind and Placebo Controlled Study (Phase IV) Terminated NCT01583062 Phase 4 Amoxicillin/clavulanic acid;Amoxicillin plus placebo
14 ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals Withdrawn NCT00396240 Phase 4 Rosuvastatin
15 Obesity Reduction Black Intervention Trial (ORBIT) Unknown status NCT00859989 Phase 3
16 Prosthetic Motility and Complications in Pegged Versus Unpegged Hydroxyapatite Orbital Implants Unknown status NCT00371280 Phase 2, Phase 3
17 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Pulmaquin® in the Management of Chronic Lung Infections With Pseudomonas Aeruginosa in Subjects With Non-Cystic Fibrosis Bronchiectasis, Including 28 Day Open-Label Extension and Pharmacokinetic Substudy (ORBIT-3) Completed NCT01515007 Phase 3 Ciprofloxacin dispersion for inhalation;Placebo
18 Infra-orbital Nerve Block for Post Operative Analgesia in Young Children Undergoing Pediatric Cleft Lip Surgery. Completed NCT02514980 Phase 2, Phase 3 Bupivacaine;Ketamine
19 PeriOcular and INTravitreal Corticosteroids for Uveitic Macular Edema Trial Completed NCT02374060 Phase 3 Periocular triamcinolone 40 mg;Intravitreal triamcinolone 4 mg;Dexamethasone intravitreal implant
20 Intraorbital Injection Versus Oral Steroid in Patients With Anterior Idiopathic Orbital Inflammation: A Randomized Clinical Trial Recruiting NCT03958344 Phase 3 Prednisolone;Triamcinolone + Betamethason
21 GALOP II Protocol for the Treatment of Unilateral Retinoblastoma Recruiting NCT03475121 Phase 3
22 The Role of Optic Nerve Sheath Fenestration in Leukemic Patients Having Increased Intracranial Pressure Active, not recruiting NCT04431882 Phase 2, Phase 3
23 Attenuation Corrected Cardiac SPECT Using the GE Hawkeye Camera System Terminated NCT00587730 Phase 2, Phase 3
24 Comparing the Reconstruction of the Orbit Fracture With a Poly Caprolactone / Tri-Calcium Phosphate ( PCL/TCP ) Implant vs. a Titanium Mesh Implant. Unknown status NCT01119144 Phase 2
25 A Prospective Single Arm Trial of Involved Field Radiotherapy Alone for Stage I-II Low Grade Non-gastric Marginal Zone Lymphoma Unknown status NCT00377195 Phase 2
26 A Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Auditory Sensory Memory Processing Unknown status NCT02426983 Phase 1, Phase 2 Dextromethorphan
27 Reconstruction of the Orbit With a Bioresorbable Polycaprolactone Implant Completed NCT00233922 Phase 2
28 A PhaseI/II Prospective, Randomized, Dose-Ranging Pilot Study of Rituximab in the Treatment of Refractory Scleritis and Non-Infectious Orbital Inflammation Completed NCT00415506 Phase 1, Phase 2 Rituximab
29 Enhancing Developmental Motor Plasticity After Perinatal Stroke With Transcranial Direct Current Stimulation Completed NCT02170285 Phase 2
30 A Single-masked, Placebo Controlled, Multi-center Pilot Study to Determine the Safety and Efficacy of Orbital Injections of a Fixed Dose of LIPO-102 in Patients With Symptomatic Exophthalmos Associated With Thyroid-related Eye Disease Completed NCT00954057 Phase 2 LIPO-102;Placebo
31 Randomized Phase II Trial On Primary Chemotherapy With High-Dose Methotrexate And High-Dose Cytarabine With Or Without Thiotepa, And With Or Without Rituximab, Followed By Brain Irradiation Vs. High-Dose Chemotherapy Supported By Autologous Stem Cells Transplantation For Immunocompetent Patients With Newly Diagnosed Primary CNS Lymphoma Completed NCT01011920 Phase 2 Methotrexate;Ara-C;Rituximab;Thiotepa;BCNU
32 Determination of the Optimum Delivery Route for the Intraglandular Administration of Botulinum Toxin A in Patients With Refractory Epiphora Completed NCT01282541 Phase 2 Botulinum Toxin Type A;Botulinum Toxin Type A
33 A Multi-center, Open Label, Multiple Dose, Phase II Trial to Demonstrate the Safety of DWP-450 in Adult Subjects for Treatment of Moderate-to-severe Glabellar Lines. Completed NCT02184988 Phase 2
34 Efficacy of Dexmedetomidine as an Adjuvant to Local Anesthetic Agent in Scalp Block and Scalp Infiltration to Control Post Craniotomy Pain Completed NCT02866409 Phase 2 Dexmedetomidine;Bupivacaine
35 A Comparative Study of Recessive Spherical Headed Silicone Intubation and Dacryocystorhinostomy Under Nasal Endoscopy in the Treatment of Nasolacrimal Duct Obstruction Completed NCT02636257 Phase 1, Phase 2
36 Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma Recruiting NCT01783535 Phase 2 vincristine;topotecan;filgrastim;PEG-filgrastim;carboplatin;etoposide;cyclophosphamide;MESNA;doxorubicin
37 Ultra Low Dose 4 Gy Orbital Radiation for Definitive Therapy of Indolent B Cell Lymphoma Recruiting NCT02494700 Phase 2 Orbital Radiation
38 Ipilimumab and Nivolumab in Combination With Immunoembolization for the Treatment of Metastatic Uveal Melanoma Recruiting NCT03472586 Phase 2 Embolization Therapy
39 Interventions to Decrease the Impact of Post-Operative Ileus After Liver Transplant or Resection Surgery Completed NCT01156129 Phase 1 stool softener
40 Investigation of Cocaine Addiction Using mGluR5 PET and fMRI Recruiting NCT03471182 Phase 1 Cocaine Self-adminstration
41 Postoperative Pain of General Anesthesia in Orbital Disease and Ocular Tumor Unknown status NCT02704715
42 Efficacy of Endoscopic Transantral Versus Transorbital Surgical Approaches in the Repair of Orbital Blow-Out Fractures-Randomized Clinical Trial. Unknown status NCT03011047
43 Evaluation of Transconjunctival Approach in Management of Orbital Tumors Unknown status NCT03195101
44 Lymphoma in the Orbit Unknown status NCT01302912
45 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436
46 the Effect of Using the Tyransconjunctival Approach Alone Versus Using Transconjunctival Approach Together With Lateral Canthotomy in Orbital Fractures Unknown status NCT03813732
47 Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan Unknown status NCT01464541
48 Fetal Orbital Measurements by 3D Ultrasound Unknown status NCT01594944
49 Resorbable Polymer Plates in Repair of Blowout Orbital Floor Fractures Unknown status NCT03683615
50 Effectiveness and Possible Complications of Core Needle Biopsy of Orbital Tumors Unknown status NCT01772355

Search NIH Clinical Center for Orbital Disease

Cochrane evidence based reviews: orbital diseases

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Genetic Tests for Orbital Disease

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Anatomical Context for Orbital Disease

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The Foundational Model of Anatomy Ontology organs/tissues related to Orbital Disease:

19
Eye Socket

MalaCards organs/tissues related to Orbital Disease:

40
Eye, Thyroid, Ciliary Ganglion, Bone, Liver, Cortex, Skin
Sources

Publications for Orbital Disease

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Articles related to Orbital Disease:

(show top 50) (show all 687)
# Title Authors PMID Year
1
Sarcoid-like granulomatous orbitopathy-presentation, systemic involvement and clinical outcome. 61
32317795 2021
2
Re: concomitant adult onset xanthogranuloma and IgG4-related orbital disease: A rare occurrence. 61
33034247 2021
3
Re: concomitant adult onset xanthogranuloma and IgG4-related orbital disease: a rare occurrence. 61
33043756 2021
4
Automatic orbital computed tomography coordinating method and quantitative error evaluation based on signed distance field. 61
32252533 2021
5
The feasibility of quantitative MRI of extra-ocular muscles in myasthenia gravis and Graves' orbitopathy. 61
32893386 2021
6
Ocular Manifestations in Rheumatoid Arthritis, Connective Tissue Disease, and Vasculitis: A Systematic Review and Metaanalysis. 61
32358156 2021
7
Radiation-Induced Hyalinizing Clear Cell Carcinoma of the Orbit. 61
32427738 2021
8
Bag-of-features-based radiomics for differentiation of ocular adnexal lymphoma and idiopathic orbital inflammation from contrast-enhanced MRI. 61
32789530 2021
9
Ocular side effects of checkpoint inhibitors. 61
33440195 2021
10
Compressive optic neuropathy with vision loss due to IgG4-related orbital disease. 61
31590594 2020
11
[Diseases and Surgery of the Orbit]. 61
33307575 2020
12
[Management of orbital inflammatory disorders in internal medicine: New findings resulting from a retrospective study of 31 consecutive patients]. 61
32861532 2020
13
A prospective randomized controlled clinical trial of Pingmu Decoction combined with acupuncture in the treatment of non-active thyroid-related ophthalmopathy. 61
33371126 2020
14
Retrobulbar metastasis of breast primary- Once in a blue moon lesion. 61
33475618 2020
15
Immunoglobulin G4-Related Orbital Disease with Bilateral Optic Perineuritis and Maxillary Nerves Involvement: A Case Report. 61
33068267 2020
16
Squamous carcinoma ex pleomorphic adenoma of the lacrimal gland. 61
33172316 2020
17
Normative Exophthalmometry Measurements Vary Among Ethiopian Adults and the Major Ethiopian Ethnic Groups. 61
32467519 2020
18
[A summary of oculoplastic and orbital surgery in China in the past 70 years]. 61
33152838 2020
19
Orbital disease in neuro-ophthalmology. 61
33009078 2020
20
The Alberta standardized orbital technique in the management of spheno-orbital meningiomas. 61
33008278 2020
21
Post-traumatic enophthalmos secondary to orbital fat atrophy: a volumetric analysis. 61
31726012 2020
22
Sinonasal Small Cell Carcinoma-Case Series of a Rare Malignancy. 61
33090899 2020
23
Measurement of proptosis using computed tomography based three-dimensional reconstruction software in patients with Graves' orbitopathy. 61
32883985 2020
24
Histopathologic Findings in Idiopathic Orbital Myositis. 61
32926913 2020
25
Orbital disease in neuro-ophthalmology. 61
32897917 2020
26
Radiographic analysis of fatty infiltration of the extraocular muscles in thyroid eye disease. 61
32878536 2020
27
Retinal and Optic Nerve Deformations Due to Orbital Versus Intracranial Venous Hypertension. 61
32956232 2020
28
[Use of the Multidisciplinary Specialised Case Conference at the Freiburg Orbital Centre]. 61
32016941 2020
29
Concomitant adult onset xanthogranuloma and IgG4-related orbital disease: a rare occurrence. 61
32847452 2020
30
Evaluate the Differences in CT Features and Serum IgG4 Levels between Lymphoma and Immunoglobulin G4-Related Disease of the Orbit. 61
32751135 2020
31
Periorbital lipogranuloma after facial injection of autologous fat: A retrospective study of 18 cases. 61
32613849 2020
32
Clinical features of immunoglobulin G4-related disease with central nervous system involvement: an analysis of 15 cases. 61
32083541 2020
33
Case Report: A Rare Case of Silent Sinus Syndrome and Vertical Diplopia. 61
32697554 2020
34
Subtotal Exenteration of the Orbit for Benign Orbital Disease. 61
32224777 2020
35
Carcinoid Tumors of the Orbit and Ocular Adnexa. 61
32496392 2020
36
T2 mapping of the extraocular muscles in healthy volunteers: preliminary research on scan-rescan and observer-observer reproducibility. 61
31581780 2020
37
Involvement of Multiple Trigeminal Nerve Branches in IgG4-Related Orbital Disease. 61
32501880 2020
38
Orbital and Ocular Adnexal Manifestations of Adult T-Cell Leukemia/Lymphoma: a Case Report and Systematic Review. 61
32427727 2020
39
IgG4-related disease: a clinical perspective. 61
32348524 2020
40
Orbital diseases mimicking graves' orbitopathy: a long-standing challenge in differential diagnosis. 61
31691261 2020
41
The expanded endonasal approach in pediatric skull base surgery: A review. 61
32337363 2020
42
The role of ultrasonography in differential diagnosis of orbital lesions. 61
32166724 2020
43
Prostaglandin analogues: A double-edged sword in orbital glaucoma disease management. 61
32043370 2020
44
A Comparative Study of Clinical vs. Digital Exophthalmometry Measurement Methods. 61
32280513 2020
45
An accurate interactive segmentation and volume calculation of orbital soft tissue for orbital reconstruction after enucleation. 61
31842802 2019
46
Orbital IgG4 Disease: Imaging Findings on 68Ga-DOTANOC PET/CT. 61
31867079 2019
47
Clinical and histopathological findings of patients with orbital granulomatosis with polyangiitis cases refractory to rituximab. 61
31836100 2019
48
[Orbital Disorders in Childhood]. 61
31412385 2019
49
[Actively promoting the research and development of artificial intelligence diagnosis and treatment of orbital disease]. 61
31715675 2019
50
Applications of three-dimensional printing in orbital diseases and disorders. 61
31261186 2019
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Variations for Orbital Disease

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Expression for Orbital Disease

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Search GEO for disease gene expression data for Orbital Disease.
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Pathways for Orbital Disease

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Pathways related to Orbital Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Thyroxine (Thyroid Hormone) Production 1
9.4 TSHR TG
Sources

GO Terms for Orbital Disease

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Biological processes related to Orbital Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sympathetic nervous system development GO:0048485 8.62 PHOX2A NF1
Sources

Sources for Orbital Disease

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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