MCID: ORB004
MIFTS: 19

Orbital Osteomyelitis

Categories: Bone diseases

Aliases & Classifications for Orbital Osteomyelitis

MalaCards integrated aliases for Orbital Osteomyelitis:

Name: Orbital Osteomyelitis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11232
ICD9CM 34 376.03
SNOMED-CT 67 65875003
ICD10 32 H05.02
UMLS 70 C0155258

Summaries for Orbital Osteomyelitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by inflammation of the medullary cavity of orbital bone that eventually spreads to the periosteum.

MalaCards based summary : Orbital Osteomyelitis is related to osteomyelitis and achenbach syndrome. An important gene associated with Orbital Osteomyelitis is CRP (C-Reactive Protein), and among its related pathways/superpathways is Folate Metabolism. Affiliated tissues include bone, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Orbital Osteomyelitis

Diseases related to Orbital Osteomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 135)
# Related Disease Score Top Affiliating Genes
1 osteomyelitis 10.2
2 achenbach syndrome 9.9 F2 CRP
3 small intestine diverticulitis 9.9 F2 CRP
4 renal pelvis squamous cell carcinoma 9.9 F2 CRP
5 synovial angioma 9.9 F2 CRP
6 hematocele of tunica vaginalis testis 9.9 F2 CRP
7 emphysematous cholecystitis 9.9 F2 CRP
8 ankylosing spondylitis 1 9.9 F2 CRP
9 cavernous sinus thrombosis 9.9 F2 CRP
10 subdural empyema 9.9 F2 CRP
11 epidural abscess 9.9 F2 CRP
12 lemierre's syndrome 9.9 F2 CRP
13 internal hemorrhoid 9.9 F2 CRP
14 hemorrhoid 9.9 F2 CRP
15 acute cor pulmonale 9.9 F2 CRP
16 acalculous cholecystitis 9.9 F2 CRP
17 intracranial sinus thrombosis 9.9 F2 CRP
18 splenic abscess 9.9 F2 CRP
19 ascending cholangitis 9.9 F2 CRP
20 cholangitis 9.9 F2 CRP
21 hemopericardium 9.9 F2 CRP
22 abducens nerve disease 9.9 F2 CRP
23 mediastinitis 9.9 F2 CRP
24 cholesterol embolism 9.9 F2 CRP
25 early congenital syphilis 9.9 F2 CRP
26 syphilis 9.9 F2 CRP
27 cauda equina syndrome 9.9 F2 CRP
28 splenic tuberculosis 9.9 F2 CRP
29 paralytic ileus 9.9 F2 CRP
30 ileus 9.9 F2 CRP
31 intracranial embolism 9.9 F2 CRP
32 acute cholangitis 9.9 F2 CRP
33 branch retinal artery occlusion 9.9 F2 CRP
34 retinal artery occlusion 9.9 F2 CRP
35 mastoiditis 9.9 F2 CRP
36 active peptic ulcer disease 9.9 F2 CRP
37 common bile duct disease 9.9 F2 CRP
38 bile duct disease 9.9 F2 CRP
39 abdominal tuberculosis 9.9 F2 CRP
40 splenic infarction 9.9 F2 CRP
41 pyuria 9.9 F2 CRP
42 pleural empyema 9.9 F2 CRP
43 kwashiorkor 9.9 F2 CRP
44 central retinal artery occlusion 9.9 F2 CRP
45 parametritis 9.9 F2 CRP
46 analbuminemia 9.9 F2 CRP
47 cardiac tamponade 9.9 F2 CRP
48 compartment syndrome 9.9 F2 CRP
49 hepatic tuberculosis 9.9 F2 CRP
50 nonbacterial thrombotic endocarditis 9.9 F2 CRP

Graphical network of the top 20 diseases related to Orbital Osteomyelitis:



Diseases related to Orbital Osteomyelitis

Symptoms & Phenotypes for Orbital Osteomyelitis

GenomeRNAi Phenotypes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-161 9.1 F2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-176 9.1 F2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.1 CRP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-49 9.1 CRP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.1 CRP
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.1 CRP

Drugs & Therapeutics for Orbital Osteomyelitis

Search Clinical Trials , NIH Clinical Center for Orbital Osteomyelitis

Genetic Tests for Orbital Osteomyelitis

Anatomical Context for Orbital Osteomyelitis

MalaCards organs/tissues related to Orbital Osteomyelitis:

40
Bone

Publications for Orbital Osteomyelitis

Articles related to Orbital Osteomyelitis:

# Title Authors PMID Year
1
Disseminated Coccidioidomycosis With Orbital Osteomyelitis and Periorbital Abscess. 61
33795607 2021
2
Orbital Osteomyelitis in the Pediatric Patient. 61
32881821 2021
3
99mTc-UBI 29-41 bone SPECT/CT scan in craniofacial Actinomyces israelii: Misdiagnosis of cranial bone tumor - A case report. 61
33408927 2020
4
Actinomyces Orbital Osteomyelitis in the Setting of Multiple Myeloma and Bisphosphonate-Related Osteonecrosis. 61
30763286 2019
5
Orbital necrotizing fasciitis and osteomyelitis caused by arcanobacterium haemolyticum: a case report. 61
24801256 2015
6
Clinical and pathological observation and treatment of chronic orbital osteomyelitis. 61
19776655 2010
7
Osteomyelitis of the orbit. 61
9076787 1997
8
Cryptococcosis in Zimbabwe. 61
3992644 1985
9
[A case of orbital osteomyelitis, suggestive of plasmacytoma]. 61
5895268 1965

Variations for Orbital Osteomyelitis

Expression for Orbital Osteomyelitis

Search GEO for disease gene expression data for Orbital Osteomyelitis.

Pathways for Orbital Osteomyelitis

Pathways related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.96 F2 CRP

GO Terms for Orbital Osteomyelitis

Biological processes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.62 F2 CRP

Sources for Orbital Osteomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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