MCID: ORB004
MIFTS: 19

Orbital Osteomyelitis

Categories: Bone diseases, Eye diseases

Aliases & Classifications for Orbital Osteomyelitis

MalaCards integrated aliases for Orbital Osteomyelitis:

Name: Orbital Osteomyelitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11232
ICD9CM 34 376.03
SNOMED-CT 67 65875003
ICD10 32 H05.02
UMLS 71 C0155258

Summaries for Orbital Osteomyelitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by inflammation of the medullary cavity of orbital bone that eventually spreads to the periosteum.

MalaCards based summary : Orbital Osteomyelitis is related to osteomyelitis and small intestine diverticulitis. An important gene associated with Orbital Osteomyelitis is CRP (C-Reactive Protein), and among its related pathways/superpathways is Folate Metabolism. Affiliated tissues include bone and eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Orbital Osteomyelitis

Diseases related to Orbital Osteomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 117)
# Related Disease Score Top Affiliating Genes
1 osteomyelitis 10.0
2 small intestine diverticulitis 9.9 F2 CRP
3 synovial angioma 9.9 F2 CRP
4 renal pelvis squamous cell carcinoma 9.9 F2 CRP
5 blue toe syndrome 9.9 F2 CRP
6 emphysematous cholecystitis 9.9 F2 CRP
7 necrotizing gastritis 9.9 F2 CRP
8 cavernous sinus thrombosis 9.9 F2 CRP
9 lemierre's syndrome 9.9 F2 CRP
10 marantic endocarditis 9.9 F2 CRP
11 endocarditis 9.9 F2 CRP
12 intracranial sinus thrombosis 9.9 F2 CRP
13 splenic abscess 9.9 F2 CRP
14 ascending cholangitis 9.9 F2 CRP
15 cholangitis 9.9 F2 CRP
16 acalculous cholecystitis 9.9 F2 CRP
17 cholesterol embolism 9.9 F2 CRP
18 branch retinal artery occlusion 9.9 F2 CRP
19 mediastinitis 9.9 F2 CRP
20 intracranial embolism 9.9 F2 CRP
21 acute cholangitis 9.9 F2 CRP
22 mastoiditis 9.9 F2 CRP
23 abdominal tuberculosis 9.9 F2 CRP
24 paralytic ileus 9.9 F2 CRP
25 ileus 9.9 F2 CRP
26 splenic infarction 9.9 F2 CRP
27 active peptic ulcer disease 9.9 F2 CRP
28 common bile duct disease 9.9 F2 CRP
29 bile duct disease 9.9 F2 CRP
30 kwashiorkor 9.9 F2 CRP
31 central retinal artery occlusion 9.9 F2 CRP
32 intestinal volvulus 9.9 F2 CRP
33 analbuminemia 9.9 F2 CRP
34 hemorrhoid 9.9 F2 CRP
35 cardiac tamponade 9.8 F2 CRP
36 papilledema 9.8 F2 CRP
37 anuria 9.8 F2 CRP
38 peripheral vertigo 9.8 F2 CRP
39 tricuspid valve insufficiency 9.8 F2 CRP
40 drug allergy 9.8 F2 CRP
41 tricuspid valve disease 9.8 F2 CRP
42 compartment syndrome 9.8 F2 CRP
43 cecal disease 9.8 F2 CRP
44 ischemic colitis 9.8 F2 CRP
45 mitral valve stenosis 9.8 F2 CRP
46 thrombophlebitis 9.8 F2 CRP
47 retinal vascular occlusion 9.8 F2 CRP
48 choledocholithiasis 9.8 F2 CRP
49 danubian endemic familial nephropathy 9.8 F2 CRP
50 aspiration pneumonia 9.8 F2 CRP

Graphical network of the top 20 diseases related to Orbital Osteomyelitis:



Diseases related to Orbital Osteomyelitis

Symptoms & Phenotypes for Orbital Osteomyelitis

GenomeRNAi Phenotypes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.47 CRP
2 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.47 F2
3 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.47 F2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-133 9.47 F2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.47 F2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.47 CRP
7 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.47 CRP F2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.47 F2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.47 CRP
10 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.47 F2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.47 CRP
12 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.47 CRP
13 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.47 F2

Drugs & Therapeutics for Orbital Osteomyelitis

Search Clinical Trials , NIH Clinical Center for Orbital Osteomyelitis

Genetic Tests for Orbital Osteomyelitis

Anatomical Context for Orbital Osteomyelitis

MalaCards organs/tissues related to Orbital Osteomyelitis:

40
Bone, Eye

Publications for Orbital Osteomyelitis

Articles related to Orbital Osteomyelitis:

# Title Authors PMID Year
1
Actinomyces Orbital Osteomyelitis in the Setting of Multiple Myeloma and Bisphosphonate-Related Osteonecrosis. 61
30763286 2019
2
Orbital necrotizing fasciitis and osteomyelitis caused by arcanobacterium haemolyticum: a case report. 61
24801256 2015
3
Clinical and pathological observation and treatment of chronic orbital osteomyelitis. 61
19776655 2010
4
Osteomyelitis of the orbit. 61
9076787 1997
5
Cryptococcosis in Zimbabwe. 61
3992644 1985
6
[A case of orbital osteomyelitis, suggestive of plasmacytoma]. 61
5895268 1965

Variations for Orbital Osteomyelitis

Expression for Orbital Osteomyelitis

Search GEO for disease gene expression data for Orbital Osteomyelitis.

Pathways for Orbital Osteomyelitis

Pathways related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.96 F2 CRP

GO Terms for Orbital Osteomyelitis

Biological processes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.62 F2 CRP

Sources for Orbital Osteomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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