MCID: ORB004
MIFTS: 19

Orbital Osteomyelitis

Categories: Bone diseases

Aliases & Classifications for Orbital Osteomyelitis

MalaCards integrated aliases for Orbital Osteomyelitis:

Name: Orbital Osteomyelitis 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11232
ICD9CM 34 376.03
SNOMED-CT 67 65875003
ICD10 32 H05.02
UMLS 71 C0155258

Summaries for Orbital Osteomyelitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by inflammation of the medullary cavity of orbital bone that eventually spreads to the periosteum.

MalaCards based summary : Orbital Osteomyelitis is related to osteomyelitis and achenbach syndrome. An important gene associated with Orbital Osteomyelitis is CRP (C-Reactive Protein), and among its related pathways/superpathways is Folate Metabolism. Affiliated tissues include bone, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Orbital Osteomyelitis

Diseases related to Orbital Osteomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 133, show less)
# Related Disease Score Top Affiliating Genes
1 osteomyelitis 10.1
2 achenbach syndrome 9.9 F2 CRP
3 small intestine diverticulitis 9.9 F2 CRP
4 renal pelvis squamous cell carcinoma 9.9 F2 CRP
5 synovial angioma 9.9 F2 CRP
6 hematocele of tunica vaginalis testis 9.9 F2 CRP
7 emphysematous cholecystitis 9.9 F2 CRP
8 ankylosing spondylitis 1 9.9 F2 CRP
9 cavernous sinus thrombosis 9.9 F2 CRP
10 subdural empyema 9.9 F2 CRP
11 epidural abscess 9.9 F2 CRP
12 lemierre's syndrome 9.9 F2 CRP
13 internal hemorrhoid 9.9 F2 CRP
14 hemorrhoid 9.9 F2 CRP
15 acute cor pulmonale 9.9 F2 CRP
16 hemopericardium 9.9 F2 CRP
17 intracranial sinus thrombosis 9.9 F2 CRP
18 splenic abscess 9.9 F2 CRP
19 ascending cholangitis 9.9 F2 CRP
20 cholangitis 9.9 F2 CRP
21 abducens nerve disease 9.9 F2 CRP
22 mediastinitis 9.9 F2 CRP
23 acalculous cholecystitis 9.9 F2 CRP
24 cholesterol embolism 9.9 F2 CRP
25 early congenital syphilis 9.9 F2 CRP
26 cauda equina syndrome 9.9 F2 CRP
27 splenic tuberculosis 9.9 F2 CRP
28 paralytic ileus 9.9 F2 CRP
29 ileus 9.9 F2 CRP
30 intracranial embolism 9.9 F2 CRP
31 acute cholangitis 9.9 F2 CRP
32 branch retinal artery occlusion 9.9 F2 CRP
33 retinal artery occlusion 9.9 F2 CRP
34 mastoiditis 9.9 F2 CRP
35 common bile duct disease 9.9 F2 CRP
36 bile duct disease 9.9 F2 CRP
37 abdominal tuberculosis 9.9 F2 CRP
38 splenic infarction 9.9 F2 CRP
39 pyuria 9.9 F2 CRP
40 pleural empyema 9.9 F2 CRP
41 kwashiorkor 9.9 F2 CRP
42 central retinal artery occlusion 9.9 F2 CRP
43 parametritis 9.9 F2 CRP
44 cardiac tamponade 9.9 F2 CRP
45 analbuminemia 9.9 F2 CRP
46 compartment syndrome 9.9 F2 CRP
47 hepatic tuberculosis 9.9 F2 CRP
48 nonbacterial thrombotic endocarditis 9.9 F2 CRP
49 endocarditis 9.9 F2 CRP
50 anuria 9.9 F2 CRP
51 cecal disease 9.9 F2 CRP
52 papilledema 9.9 F2 CRP
53 volvulus of midgut 9.9 F2 CRP
54 choledocholithiasis 9.9 F2 CRP
55 tricuspid valve disease 9.9 F2 CRP
56 tricuspid valve insufficiency 9.9 F2 CRP
57 peripheral vertigo 9.9 F2 CRP
58 thrombophlebitis 9.9 F2 CRP
59 ischemic colitis 9.9 F2 CRP
60 aortic valve insufficiency 9.9 F2 CRP
61 retinal vascular occlusion 9.9 F2 CRP
62 mitral valve stenosis 9.9 F2 CRP
63 aspiration pneumonia 9.9 F2 CRP
64 pneumonia 9.9 F2 CRP
65 mitral valve insufficiency 9.9 F2 CRP
66 pericardium disease 9.9 F2 CRP
67 cellulitis 9.9 F2 CRP
68 plasma protein metabolism disease 9.9 F2 CRP
69 endocardium disease 9.9 F2 CRP
70 pulmonary artery disease 9.9 F2 CRP
71 splenic disease 9.9 F2 CRP
72 chronic venous insufficiency 9.9 F2 CRP
73 venous insufficiency 9.9 F2 CRP
74 portal vein thrombosis 9.9 F2 CRP
75 hepatic vascular disease 9.9 F2 CRP
76 vascular disease 9.9 F2 CRP
77 leptospirosis 9.9 F2 CRP
78 autoimmune disease of cardiovascular system 9.9 F2 CRP
79 intermittent claudication 9.9 F2 CRP
80 vein disease 9.9 F2 CRP
81 pericardial effusion 9.9 F2 CRP
82 infective endocarditis 9.9 F2 CRP
83 acute cystitis 9.9 F2 CRP
84 exanthem 9.9 F2 CRP
85 obstructive jaundice 9.9 F2 CRP
86 nonarteritic anterior ischemic optic neuropathy 9.9 F2 CRP
87 mitral valve disease 9.9 F2 CRP
88 typhoid fever 9.9 F2 CRP
89 purpura 9.9 F2 CRP
90 bilirubin metabolic disorder 9.9 F2 CRP
91 pulmonary edema 9.9 F2 CRP
92 homocysteinemia 9.9 F2 CRP
93 moyamoya disease 1 9.9 F2 CRP
94 disseminated intravascular coagulation 9.9 F2 CRP
95 nutritional deficiency disease 9.9 F2 CRP
96 antiphospholipid syndrome 9.9 F2 CRP
97 alcoholic hepatitis 9.9 F2 CRP
98 placenta disease 9.8 F2 CRP
99 autoimmune disease of gastrointestinal tract 9.8 F2 CRP
100 thrombocytosis 9.8 F2 CRP
101 pulmonary embolism 9.8 F2 CRP
102 heart valve disease 9.8 F2 CRP
103 cholangitis, primary sclerosing 9.8 F2 CRP
104 myeloma, multiple 9.8
105 osteonecrosis 9.8
106 frontal sinusitis 9.8
107 plasmacytoma 9.8
108 peritonitis 9.8 F2 CRP
109 atrial heart septal defect 9.8 F2 CRP
110 biliary tract disease 9.8 F2 CRP
111 hellp syndrome 9.8 F2 CRP
112 peripheral vascular disease 9.8 F2 CRP
113 viral hepatitis 9.8 F2 CRP
114 patent foramen ovale 9.8 F2 CRP
115 inherited metabolic disorder 9.8 F2 CRP
116 blood platelet disease 9.8 F2 CRP
117 speech and communication disorders 9.8 F2 CRP
118 blood coagulation disease 9.8 F2 CRP
119 sickle cell anemia 9.8 F2 CRP
120 atrial fibrillation 9.8 F2 CRP
121 essential thrombocythemia 9.8 F2 CRP
122 beta-thalassemia 9.8 F2 CRP
123 heart conduction disease 9.8 F2 CRP
124 behcet syndrome 9.8 F2 CRP
125 cerebrovascular disease 9.8 F2 CRP
126 hemorrhagic disease 9.7 F2 CRP
127 migraine with or without aura 1 9.7 F2 CRP
128 familial hypercholesterolemia 9.7 F2 CRP
129 respiratory failure 9.7 F2 CRP
130 stroke, ischemic 9.7 F2 CRP
131 hypothyroidism 9.6 F2 CRP
132 pre-eclampsia 9.6 F2 CRP
133 liver cirrhosis 9.5 F2 CRP

Graphical network of the top 20 diseases related to Orbital Osteomyelitis:



Diseases related to Orbital Osteomyelitis

Symptoms & Phenotypes for Orbital Osteomyelitis

GenomeRNAi Phenotypes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

26 (showing 6, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-161 9.1 F2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-176 9.1 F2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.1 CRP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-49 9.1 CRP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.1 CRP
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.1 CRP

Drugs & Therapeutics for Orbital Osteomyelitis

Search Clinical Trials , NIH Clinical Center for Orbital Osteomyelitis

Genetic Tests for Orbital Osteomyelitis

Anatomical Context for Orbital Osteomyelitis

MalaCards organs/tissues related to Orbital Osteomyelitis:

40
Bone

Publications for Orbital Osteomyelitis

Articles related to Orbital Osteomyelitis:

(showing 8, show less)
# Title Authors PMID Year
1
Orbital Osteomyelitis in the Pediatric Patient. 61
32881821 2021
2
99mTc-UBI 29-41 bone SPECT/CT scan in craniofacial Actinomyces israelii: Misdiagnosis of cranial bone tumor - A case report. 61
33408927 2020
3
Actinomyces Orbital Osteomyelitis in the Setting of Multiple Myeloma and Bisphosphonate-Related Osteonecrosis. 61
30763286 2019
4
Orbital necrotizing fasciitis and osteomyelitis caused by arcanobacterium haemolyticum: a case report. 61
24801256 2015
5
Clinical and pathological observation and treatment of chronic orbital osteomyelitis. 61
19776655 2010
6
Osteomyelitis of the orbit. 61
9076787 1997
7
Cryptococcosis in Zimbabwe. 61
3992644 1985
8
[A case of orbital osteomyelitis, suggestive of plasmacytoma]. 61
5895268 1965

Variations for Orbital Osteomyelitis

Expression for Orbital Osteomyelitis

Search GEO for disease gene expression data for Orbital Osteomyelitis.

Pathways for Orbital Osteomyelitis

Pathways related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

(showing 1, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.96 F2 CRP

GO Terms for Orbital Osteomyelitis

Biological processes related to Orbital Osteomyelitis according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 8.62 F2 CRP

Sources for Orbital Osteomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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