MCID: ORB008
MIFTS: 32

Orbital Plasma Cell Granuloma

Categories: Eye diseases

Aliases & Classifications for Orbital Plasma Cell Granuloma

MalaCards integrated aliases for Orbital Plasma Cell Granuloma:

Name: Orbital Plasma Cell Granuloma 12 15 17
Orbital Myositis 12 17 74
Orbital Pseudotumor 45 74
Plasma Cell Granuloma, Orbital 74
Pseudotumor of Orbit 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9369
MeSH 45 D016727
SNOMED-CT 69 72789009
ICD10 34 H05.11

Summaries for Orbital Plasma Cell Granuloma

MalaCards based summary : Orbital Plasma Cell Granuloma, also known as orbital myositis, is related to thyroiditis and myositis. An important gene associated with Orbital Plasma Cell Granuloma is TNFRSF1B (TNF Receptor Superfamily Member 1B), and among its related pathways/superpathways are Allograft rejection and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include thyroid, eye and t cells.

Related Diseases for Orbital Plasma Cell Granuloma

Diseases related to Orbital Plasma Cell Granuloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 thyroiditis 29.4 CTLA4 TSHR
2 myositis 10.9
3 crohn's disease 10.4
4 juvenile ankylosing spondylitis 10.3 MRAP TNFRSF1B
5 scleral disease 10.3 MRAP TNFRSF1B
6 pustulosis of palm and sole 10.3 MRAP TNFRSF1B
7 iritis 10.3 MRAP TNFRSF1B
8 herpes zoster 10.3
9 tenosynovitis 10.3 MRAP TNFRSF1B
10 pericoronitis 10.3 NCAM1 TNFRSF1B
11 rhinoscleroma 10.3 NCAM1 TNFRSF1B
12 transient arthritis 10.3 MRAP TNFRSF1B
13 peroneal neuropathy 10.3 MME TNFRSF1B
14 panuveitis 10.3 MRAP TNFRSF1B
15 penile disease 10.2 IFNA2 MRAP
16 conjunctival disease 10.2 IFNA2 MRAP
17 lyme disease 10.2
18 herpes zoster ophthalmicus 10.2
19 hypersensitivity reaction type iv disease 10.2 MRAP TNFRSF1B
20 palindromic rheumatism 10.2 MRAP TNFRSF1B
21 lung combined type small cell carcinoma 10.2 MME NCAM1
22 extrahepatic bile duct adenocarcinoma 10.2 MME NCAM1
23 myocarditis 10.2
24 myxedema 10.2 CTLA4 TSHR
25 spermatocele 10.2 MME NCAM1
26 rete testis neoplasm 10.2 MME NCAM1
27 cystadenofibroma 10.2 MME NCAM1
28 uveal disease 10.2 MRAP TNFRSF1B
29 arthritis 10.2
30 lupus erythematosus 10.2
31 giant cell myocarditis 10.2
32 pediatric lymphoma 10.1 MME NCAM1
33 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1 CTLA4 TSHR
34 histrionic personality disorder 10.1 KNTC1 MME
35 autoimmune disease of endocrine system 10.1 CTLA4 TSHR
36 granulomatous myositis 10.1 NCAM1 PIK3C2A TNFRSF1B
37 nephrogenic adenofibroma 10.1 MME NCAM1
38 lymphatic system cancer 10.1 MME NCAM1
39 exanthem 10.1 CTLA4 TNFRSF1B
40 dependent personality disorder 10.1 KNTC1 MME
41 rheumatoid arthritis 10.1
42 cellulitis 10.1
43 anterior scleritis 10.1 MRAP NCAM1 TNFRSF1B
44 carcinoid syndrome 10.1 IFNA2 SST
45 pancreatic endocrine carcinoma 10.1 NCAM1 SST
46 encapsulated thymoma 10.1 MME SST
47 acute salpingitis 10.1 MME MRAP TNFRSF1B
48 mature b-cell neoplasm 10.1 MME NCAM1
49 systemic lupus erythematosus 10.0
50 colitis 10.0

Graphical network of the top 20 diseases related to Orbital Plasma Cell Granuloma:



Diseases related to Orbital Plasma Cell Granuloma

Symptoms & Phenotypes for Orbital Plasma Cell Granuloma

Drugs & Therapeutics for Orbital Plasma Cell Granuloma

Search Clinical Trials , NIH Clinical Center for Orbital Plasma Cell Granuloma

Cochrane evidence based reviews: orbital pseudotumor

Genetic Tests for Orbital Plasma Cell Granuloma

Anatomical Context for Orbital Plasma Cell Granuloma

MalaCards organs/tissues related to Orbital Plasma Cell Granuloma:

42
Thyroid, Eye, T Cells, Heart, Skin, Testis, Myeloid

Publications for Orbital Plasma Cell Granuloma

Articles related to Orbital Plasma Cell Granuloma:

(show top 50) (show all 162)
# Title Authors Year
1
Orbital myositis as a manifestation of primary antiphospholipid syndrome. ( 29124440 )
2018
2
Orbital Myositis: An Underrecognized Clinical Syndrome with a Need of Management Guidelines. ( 29334042 )
2018
3
A Case of Orbital Myositis Presenting With Dizziness. ( 30087737 )
2018
4
Rare case of herpes zoster ophthalmicus with orbital myositis, oculomotor nerve palsy and anterior uveitis. ( 28195080 )
2017
5
Idiopathic orbital myositis presenting as cluster headache: a case report. ( 28342020 )
2017
6
Giant cell myocarditis masquerading as orbital myositis with a rapid, fulminant course necessitating mechanical support and heart transplantation. ( 28772042 )
2017
7
Orbital myositis: A rare complication of ophthalmic herpes zoster. ( 27595510 )
2017
8
Decreased CD3-CD16+CD56+ natural killer cell counts in children with orbital myositis: a clue to disease activity. ( 28955482 )
2017
9
Alternating and Relapsing Migratory Orbital Myositis. ( 29230978 )
2017
10
Orbital myositis presenting with only unilateral orbital pain. ( 28578311 )
2017
11
Shingles as the underlying cause of orbital myositis in an adolescent: A case report. ( 29503961 )
2017
12
Orbital myositis revealing a vegetal intraorbital foreign body: a case report. ( 29877559 )
2017
13
Orbital Myositis. ( 27462048 )
2017
14
Unilateral Migratory Relapsing Orbital Myositis While on Immunosuppressant Therapy: An Uncommon Entity. ( 25564259 )
2017
15
Orbital Myositis as Both a Presenting and Associated Extraintestinal Sign of Crohn's Disease. ( 26154590 )
2017
16
Unique case of orbital myositis and dacryoadenitis preceding the vesicular rash of herpes zoster ophthalmicus. ( 26222135 )
2016
17
Giant cell myocarditis: a life-threatening disorder heralded by orbital myositis. ( 27009192 )
2016
18
Fulminant lymphocytic myocarditis associated with orbital myositis and diaphragmatic paralysis. ( 26481055 )
2016
19
Teaching NeuroImages: Painful diplopia and Crohn disease: Think about orbital myositis. ( 27527545 )
2016
20
Orbital Myositis: Evaluating Five New Cases Regarding Clinical and Radiological Features. ( 28360792 )
2016
21
"Orbiting around" the orbital myositis: clinical features, differential diagnosis and therapy. ( 26477021 )
2016
22
Orbital myositis secondary to statin therapy. ( 26510805 )
2015
23
Medical and Surgical Treatment in Pediatric Orbital Myositis Associated with Coxsackie Virus. ( 26550508 )
2015
24
Orbital myositis: a side effect of interferon alpha 2b treatment. ( 25565215 )
2015
25
Painful ophthalmoplaegia secondary to orbital myositis. ( 25948858 )
2015
26
Idiopathic Orbital Myositis in a 9-Year-Old Girl: A Case Report. ( 26199706 )
2015
27
Orbital Myositis and Primary Sjögren Syndrome. ( 26233955 )
2015
28
External ophthalmoplegia with orbital myositis in an adult patient after chickenpox infection. ( 24835802 )
2014
29
Orbital myositis associated with discoid lupus erythematosus. ( 24335011 )
2014
30
Acute monolateral proptosis and orbital myositis in a patient with discoid lupus erythematosus: a case report. ( 25410119 )
2014
31
Idiopathic inflammatory orbital myositis presenting with vision loss. ( 25207637 )
2014
32
Systemic Lupus Erythematosus Presenting as Orbital Myositis. ( 27928311 )
2014
33
Orbital myositis associated with celiac disease. ( 23842704 )
2014
34
Orbital myositis and Crohn's disease. ( 24267905 )
2014
35
Orbital myositis in Behçet's disease. ( 24326194 )
2014
36
Successful "medical" orbital decompression with adjunctive rituximab for severe visual loss in IgG4-related orbital inflammatory disease with orbital myositis. ( 24481505 )
2014
37
Orbital myositis. ( 24481807 )
2014
38
Idiopathic orbital myositis. ( 24670274 )
2014
39
Recurrent orbital myositis in undifferentiated connective tissue disease. ( 22840478 )
2013
40
Idiopathic orbital myositis associated with Graves' disease. ( 23545676 )
2013
41
Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature. ( 23556424 )
2013
42
Orbital myositis as manifestation of systemic lupus erythematosus--a case report. ( 22967713 )
2013
43
Painful ophthalmoplegia with simultaneous orbital myositis, optic and oculomotor nerve inflammation and trigeminal nucleus involvement in a patient with herpes zoster ophthalmicus. ( 23109414 )
2012
44
Acute orbital myositis before Herpes zoster ophthalmicus. ( 22474562 )
2012
45
Orbital myositis and psoriatic arthritis. ( 23217511 )
2012
46
Orbital myositis associated with focal active colitis in a teenage girl. ( 22009155 )
2012
47
IgG4-related systemic disease as a cause of "idiopathic" orbital inflammation, including orbital myositis, and trigeminal nerve involvement. ( 22018678 )
2012
48
A unique case of foreign-body associated orbital myositis. ( 22082591 )
2012
49
Bilateral diffuse orbital myositis in a patient with relapsing ulcerative colitis. ( 22366668 )
2012
50
Recurrent orbital myositis as an extra-intestinal manifestation of Crohn's disease. ( 22704659 )
2012

Variations for Orbital Plasma Cell Granuloma

Expression for Orbital Plasma Cell Granuloma

Search GEO for disease gene expression data for Orbital Plasma Cell Granuloma.

Pathways for Orbital Plasma Cell Granuloma

GO Terms for Orbital Plasma Cell Granuloma

Cellular components related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.23 CTLA4 KNTC1 MME MRAP NCAM1 PIK3C2A

Biological processes related to Orbital Plasma Cell Granuloma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.13 IFNA2 SST TSHR
2 cell surface receptor signaling pathway GO:0007166 8.92 IFNA2 SST TNFRSF1B TSHR

Sources for Orbital Plasma Cell Granuloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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