MCID: ORB003
MIFTS: 20

Orbital Tenonitis

Categories: Eye diseases

Aliases & Classifications for Orbital Tenonitis

MalaCards integrated aliases for Orbital Tenonitis:

Name: Orbital Tenonitis 12 15
Tenonitis 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11233
ICD9CM 34 376.04
SNOMED-CT 67 8976003
UMLS 71 C0155259

Summaries for Orbital Tenonitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by inflammation of the capsule of Tenon.

MalaCards based summary : Orbital Tenonitis, also known as tenonitis, is related to macular retinal edema and hydrops, lactic acidosis, and sideroblastic anemia. An important gene associated with Orbital Tenonitis is SLC26A3 (Solute Carrier Family 26 Member 3). Affiliated tissues include eye and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Orbital Tenonitis

Diseases related to Orbital Tenonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
# Related Disease Score Top Affiliating Genes
1 macular retinal edema 10.6
2 hydrops, lactic acidosis, and sideroblastic anemia 10.6
3 intraocular pressure quantitative trait locus 10.5
4 uveitis 10.4
5 diabetic macular edema 10.4
6 strabismus 10.4
7 cataract 10.4
8 mechanical strabismus 10.4
9 retinal vein occlusion 10.4
10 microvascular complications of diabetes 5 10.3
11 retinal detachment 10.3
12 ptosis 10.3
13 central retinal vein occlusion 10.2
14 pain agnosia 10.2
15 glaucoma, primary open angle 10.1
16 macular degeneration, age-related, 1 10.1
17 open-angle glaucoma 10.1
18 hair whorl 10.0
19 keratitis, hereditary 10.0
20 gyrate atrophy of choroid and retina 10.0
21 yemenite deaf-blind hypopigmentation syndrome 10.0
22 microvascular complications of diabetes 1 10.0
23 microvascular complications of diabetes 2 10.0
24 mumps 10.0
25 arteriovenous malformation 10.0
26 posterior uveitis 10.0
27 scleritis 10.0
28 endophthalmitis 10.0
29 eye disease 10.0
30 ocular hypertension 10.0
31 arteriovenous malformations of the brain 9.9
32 autoimmune disease 9.9
33 hepatocellular carcinoma 9.9
34 duane retraction syndrome 1 9.9
35 exudative vitreoretinopathy 1 9.9
36 ocular cicatricial pemphigoid 9.9
37 exfoliation syndrome 9.9
38 sarcoidosis 1 9.9
39 lung cancer 9.9
40 coats disease 9.9
41 mycobacterium tuberculosis 1 9.9
42 severe cutaneous adverse reaction 9.9
43 erythema multiforme 9.9
44 cytomegalovirus retinitis 9.9
45 optic papillitis 9.9
46 neuroretinitis 9.9
47 monocular esotropia 9.9
48 paralytic squint 9.9
49 abducens nerve disease 9.9
50 orbital cellulitis 9.9

Graphical network of the top 20 diseases related to Orbital Tenonitis:



Diseases related to Orbital Tenonitis

Symptoms & Phenotypes for Orbital Tenonitis

GenomeRNAi Phenotypes related to Orbital Tenonitis according to GeneCards Suite gene sharing:

26 (show all 18)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.56 SLC26A3
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.56 CRP
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.56 SLC26A3
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.56 CRP
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.56 SLC26A3
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.56 CRP SLC26A3
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-98 9.56 SLC26A3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.4 SLC26A3
9 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.4 CRP SLC26A3
10 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.4 SLC26A3
11 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.4 SLC26A3
12 Increased shRNA abundance (Z-score > 2) GR00366-A-147 9.4 CRP
13 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.4 CRP
14 Increased shRNA abundance (Z-score > 2) GR00366-A-180 9.4 CRP
15 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.4 CRP
16 Increased shRNA abundance (Z-score > 2) GR00366-A-54 9.4 SLC26A3
17 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.4 CRP
18 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.4 SLC26A3

Drugs & Therapeutics for Orbital Tenonitis

Search Clinical Trials , NIH Clinical Center for Orbital Tenonitis

Genetic Tests for Orbital Tenonitis

Anatomical Context for Orbital Tenonitis

MalaCards organs/tissues related to Orbital Tenonitis:

40
Eye, Testes

Publications for Orbital Tenonitis

Articles related to Orbital Tenonitis:

(show all 19)
# Title Authors PMID Year
1
Surgery, pathology, and art in Pietro Gradenigo's ophthalmologic waxworks. 61
24232084 2013
2
Cogan's syndrome: a cause of progressive hearing deafness. 61
16360829 2006
3
[Clinical course of isolated larval infestation of orbit in children]. 61
10918851 2000
4
[Surgical treatment of congenital myopia in children]. 61
2797675 1989
5
[Goethe's eye disease]. 61
6384643 1984
6
Secondary vascular glaucoma. 61
6662006 1983
7
Idiopathic inflammatory orbital pseudotumor in childhood. II. Results of diagnostic tests and biopsies. 61
7267028 1981
8
[Use of antibiotics for preventing suppurative inflammatory complications in scleroplastic operations for myopic disease]. 61
7416737 1980
9
Chronic fibrous tenonitis with vitreous hemorrhage and choroidal indentation. 61
655246 1978
10
Ultrasonic evidence of inflammatory thickening and fluid collection within the retrobulbar fascia: the T sign. 61
580171 1977
11
Puerperal sepsis leading to bilateral fulminating purulent endophthalmitis with tenonitis. 61
4757342 1973
12
[An acute attack of glaucoma in serous tenonitis]. 61
5615711 1967
13
["Tenonitis"]. 61
13907074 1961
14
[Tenonitis with papillitis]. 61
13736957 1960
15
Serous tenonitis. 61
13532100 1958
16
Tenonitis complicating mumps. 61
20997666 1946
17
Tenonitis complicating mumps. 61
21003914 1945
18
A CASE OF BRAWNY TENONITIS. 61
18168756 1928
19
NON-PURULENT TENONITIS. 61
20771428 1924

Variations for Orbital Tenonitis

Expression for Orbital Tenonitis

Search GEO for disease gene expression data for Orbital Tenonitis.

Pathways for Orbital Tenonitis

GO Terms for Orbital Tenonitis

Sources for Orbital Tenonitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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