MCID: ORN001
MIFTS: 42

Ornithosis

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Ornithosis

MalaCards integrated aliases for Ornithosis:

Name: Ornithosis 12 77 54 15 17
Psittacosis 12 77 54 56 45 74 3
Chlamydial Pneumonia 54 74
Chlamydia Psittaci Infection 74
Chlamydia Psittaci 54

Classifications:



External Ids:

Disease Ontology 12 DOID:11262
ICD9CM 36 073 073.9
MeSH 45 D009956
NCIt 51 C34873
SNOMED-CT 69 75116005
ICD10 34 A70 J16.0

Summaries for Ornithosis

Disease Ontology : 12 A primary bacterial infectious disease that results in systemic infection, has material basis in Chlamydia psittaci, which is transmitted by inhaling aerosolized dried droppings or transmitted by contact with infected birds. The infection has symptom fever, has symptom headache, has symptom rash, has symptom chills, and has symptom pneumonia.

MalaCards based summary : Ornithosis, also known as psittacosis, is related to lymphoma and pneumonia, and has symptoms including fever, headache and pneumonia. An important gene associated with Ornithosis is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha). The drugs Erythromycin and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and heart.

Wikipedia : 77 Psittacosis—also known as parrot fever, and ornithosis—is a zoonotic infectious disease in humans caused... more...

Related Diseases for Ornithosis

Diseases related to Ornithosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 lymphoma 10.4
2 pneumonia 10.3
3 lymphoma, mucosa-associated lymphoid type 10.3
4 keratoconjunctivitis 10.3
5 chlamydia 10.2
6 lymphogranuloma venereum 10.2
7 salmonellosis 10.2
8 encephalitis 10.2
9 b-cell lymphomas 10.2
10 upper respiratory tract disease 10.2
11 legionnaires' disease 10.1
12 conjunctivitis 10.1
13 legionnaire disease 10.1
14 legionellosis 10.1
15 myocarditis 10.1
16 influenza 10.1
17 cat-scratch disease 10.0
18 inclusion conjunctivitis 10.0
19 alpha-1-antitrypsin deficiency 10.0
20 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
21 ectopic pregnancy 10.0
22 nodal marginal zone lymphoma 10.0
23 sensorineural hearing loss 10.0
24 endometritis 10.0
25 pelvic inflammatory disease 10.0
26 interstitial nephritis 10.0
27 optic neuritis 10.0
28 patulous eustachian tube 10.0
29 uveitis 10.0
30 chronic follicular conjunctivitis 10.0
31 neuritis 10.0
32 rhinitis 10.0
33 avian influenza 10.0
34 infertility 10.0
35 subacute thyroiditis 10.0
36 thyroiditis 10.0
37 interstitial keratitis 10.0
38 sudden sensorineural hearing loss 10.0
39 transverse myelitis 10.0
40 acute transverse myelitis 10.0
41 infective endocarditis 9.9
42 disseminated intravascular coagulation 9.9
43 hemopericardium 9.9
44 pericardial effusion 9.9
45 typhoid fever 9.9
46 malaria 9.9
47 arthritis 9.9
48 lymphomatoid granulomatosis 9.9
49 erythema multiforme 9.9
50 endocarditis 9.9

Graphical network of the top 20 diseases related to Ornithosis:



Diseases related to Ornithosis

Symptoms & Phenotypes for Ornithosis

Symptoms:

12
  • fever
  • headache
  • pneumonia
  • chills
  • rash

Drugs & Therapeutics for Ornithosis

Drugs for Ornithosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 28)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560 441411
2
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 447043
3
Clarithromycin Approved Phase 4 81103-11-9 84029
4 Cytochrome P-450 Enzyme Inhibitors Phase 4
5 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
6 Cytochrome P-450 CYP3A Inhibitors Phase 4
7 Erythromycin stearate Phase 4
8 Anti-Infective Agents Phase 4,Phase 2,Not Applicable
9 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
10 Antitubercular Agents Phase 4,Phase 2,Not Applicable
11 Erythromycin Estolate Phase 4
12 Erythromycin Ethylsuccinate Phase 4
13
Simvastatin Approved Phase 3 79902-63-9 54454
14 Tranquilizing Agents Phase 3
15 Antipsychotic Agents Phase 3
16 Anticholesteremic Agents Phase 3
17 Lipid Regulating Agents Phase 3
18 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 3
19 Central Nervous System Depressants Phase 3
20 Psychotropic Drugs Phase 3
21 Antimetabolites Phase 3
22 Hypolipidemic Agents Phase 3
23
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
24
Rifabutin Approved, Investigational Phase 2 72559-06-9 6323490 46783538
25 Antimalarials Phase 2
26 Antiparasitic Agents Phase 2
27 Antiprotozoal Agents Phase 2
28 Vaccines

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
2 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
3 ASTHMA (AntibioticS To Help Manage Asthma) Pilot Study Completed NCT00245908 Phase 3 azithromycin
4 Simvastatin Addition for Patients With Recent-onset Schizophrenia Recruiting NCT01999309 Phase 3 Simvastatin;Placebo
5 Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease Recruiting NCT03618108 Phase 2 Doxycycline Capsule;Azithromycin Capsule;Rifabutin Oral Capsule;Placebo oral capsule;Placebo Oral Tablet;Placebo oral capsule
6 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
7 Detection of Microorganisms and Antibiotic Resistance Genes Using the Curetis Unyvero LRT55 Application Completed NCT01922024
8 Detection of Enterovirus RNA in Atheromatous Lesions Completed NCT00674531 Not Applicable
9 Prospective Study of Frontline H Pylori Eradication in the Treatment of Early-stage Extragastric MALT Lymphoma Recruiting NCT02987127
10 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
11 A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia Recruiting NCT02963142
12 DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia Recruiting NCT03360851 Not Applicable
13 Study of the Involvement of IL-17 / IL-22 Pathway in Bacterial Exacerbations of COPD Recruiting NCT02655302 Not Applicable

Search NIH Clinical Center for Ornithosis

Cochrane evidence based reviews: psittacosis

Genetic Tests for Ornithosis

Anatomical Context for Ornithosis

MalaCards organs/tissues related to Ornithosis:

42
Testes, Lung, Heart, Skin, Brain, Skeletal Muscle, T Cells

Publications for Ornithosis

Articles related to Ornithosis:

(show top 50) (show all 821)
# Title Authors Year
1
Customs officers in relation to viral infections, tuberculosis, psittacosis and environmental health risk. ( 30679987 )
2019
2
Human psittacosis: a review with emphasis on surveillance in Belgium. ( 30882289 )
2019
3
Disease burden of psittacosis in the Netherlands. ( 29361998 )
2018
4
An unusual presentation of a case of human psittacosis. ( 29719801 )
2018
5
A Psittacosis Outbreak among English Office Workers with Little or No Contact with Birds, August 2015. ( 29854568 )
2018
6
Wild and domestic bird faeces likely source of psittacosis transmission-A case-control study in Sweden, 2014-2016. ( 29984469 )
2018
7
Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue. ( 30151406 )
2018
8
Laboratory methods for case finding in human psittacosis outbreaks: a systematic review. ( 30165831 )
2018
9
Epidemiological and molecular characteristics of Chlamydia psittaci from 8 human cases of psittacosis and 4 related birds in Argentina. ( 28734713 )
2017
10
Compendium of Measures to Control Chlamydia psittaci Infection Among Humans (Psittacosis) and Pet Birds (Avian Chlamydiosis), 2017. ( 28891690 )
2017
11
Multilocus sequence typing identifies an avian-like Chlamydia psittaci strain involved in equine placentitis and associated with subsequent human psittacosis. ( 28196971 )
2017
12
Intersectoral action for health: preventing psittacosis spread after one reported case. ( 28554339 )
2017
13
An outbreak of psittacosis at a veterinary school demonstrating a novel source of infection. ( 28616500 )
2017
14
Temporal and spatial analysis of psittacosis in association with poultry farming in the Netherlands, 2000-2015. ( 28747153 )
2017
15
Managing a cluster outbreak of psittacosis in Belgium linked to a pet shop visit in The Netherlands. ( 26669637 )
2016
16
Psittacosis: Rare Respiratory Problem in Children. ( 27539767 )
2016
17
Investigation and management of psittacosis in a public aviary: A One Health approach. ( 29770013 )
2016
18
Outbreak of psittacosis in a group of women exposed to Chlamydia psittaci-infected chickens. ( 26111240 )
2015
19
Typing of Chlamydia psittaci to monitor epidemiology of psittacosis and aid disease control in the Netherlands, 2008 to 2013. ( 25677053 )
2015
20
Clinical features of endemic community-acquired psittacosis. ( 25356332 )
2014
21
Multiple human-to-human transmission from a severe case of psittacosis, Sweden, January-February 2013. ( 25358043 )
2014
22
A novel psittacine adenovirus identified during an outbreak of avian chlamydiosis and human psittacosis: zoonosis associated with virus-bacterium coinfection in birds. ( 25474263 )
2014
23
Risk exposures for human ornithosis in a poultry processing plant modified by use of personal protective equipment: an analytical outbreak study. ( 23176790 )
2013
24
Family outbreak of psittacosis with an exhumation-based diagnosis: following in the footsteps of Dr. House. ( 23187301 )
2013
25
First report of human psittacosis in Vietnam. ( 23228501 )
2013
26
Unusual increase of psittacosis in southern Sweden linked to wild bird exposure, January to April 2013. ( 23725809 )
2013
27
Zoonotic atypical pneumonia due to Chlamydophila psittaci: first reported psittacosis case in Taiwan. ( 23927984 )
2013
28
Psittacosis outbreak in Tayside, Scotland, December 2011 to February 2012. ( 22687915 )
2012
29
A case of acute psittacosis with severe abdominal pain. ( 21212142 )
2011
30
Psittacosis outbreak after participation in a bird fair, Western France, December 2008. ( 21396150 )
2011
31
Psittacosis. ( 20171542 )
2010
32
Chlamydial infections in duck farms associated with human cases of psittacosis in France. ( 18947944 )
2009
33
Psittacosis presenting as a halo sign on high-resolution computed tomography. ( 19465839 )
2009
34
An outbreak of psittacosis in a bird park in Japan. ( 17559693 )
2008
35
Chlamydophila psittaci infections in humans during an outbreak of psittacosis from poultry in Germany. ( 18387139 )
2008
36
Local newspaper as a diagnostic aid for psittacosis: a case report. ( 18540809 )
2008
37
Familial outbreak of psittacosis as the first Chlamydia psittaci infection reported from Turkey. ( 18701984 )
2008
38
Two fatal cases of psittacosis caused by Chlamydophila psittaci. ( 18809562 )
2008
39
Multiple sites of exposure in an outbreak of ornithosis in workers at a poultry abattoir and farm. ( 17274860 )
2007
40
A fatal case of psittacosis in Slovakia, January 2006. ( 17880885 )
2007
41
Local cluster of psittacosis after bird show in the Netherlands, November 2007. ( 18082112 )
2007
42
A case of fulminant psittacosis. ( 16536718 )
2006
43
Sepsis due to gestational psittacosis: A multidisciplinary approach within a perinatological center--review of reported cases. ( 16596904 )
2006
44
An outbreak of psittacosis due to Chlamydophila psittaci genotype A in a veterinary teaching hospital. ( 17030918 )
2006
45
Psittacosis in all four members of a family in Nagasaki, Japan. ( 17060709 )
2006
46
Compendium of measures to control Chlamydophila psittaci (formerly Chlamydia psittaci) infection among humans (psittacosis) and pet birds, 2005. ( 15742693 )
2005
47
Probable psittacosis outbreak linked to wild birds. ( 15757553 )
2005
48
A woman with a lobar infiltrate due to psittacosis detected by polymerase chain reaction. ( 12953962 )
2003
49
Familial cases of psittacosis: possible person-to-person transmission. ( 12132529 )
2002
50
Psittacosis/avian chlamydiosis. ( 12494967 )
2002

Variations for Ornithosis

Expression for Ornithosis

Search GEO for disease gene expression data for Ornithosis.

Pathways for Ornithosis

GO Terms for Ornithosis

Molecular functions related to Ornithosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol binding GO:0035091 8.62 NCF4 PIK3C2A

Sources for Ornithosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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