MCID: ORN001
MIFTS: 38

Ornithosis

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Ornithosis

MalaCards integrated aliases for Ornithosis:

Name: Ornithosis 12 76 53 15
Psittacosis 12 76 53 55 3 44 73
Chlamydial Pneumonia 53 73
Chlamydia Psittaci Infection 73
Chlamydia Psittaci 53

Classifications:



External Ids:

Disease Ontology 12 DOID:11262
ICD10 33 A70 J16.0
ICD9CM 35 073 073.9
MeSH 44 D009956
NCIt 50 C34873
SNOMED-CT 68 75116005

Summaries for Ornithosis

Disease Ontology : 12 A primary bacterial infectious disease that results in systemic infection, has material basis in Chlamydia psittaci, which is transmitted by inhaling aerosolized dried droppings or transmitted by contact with infected birds. The infection has symptom fever, has symptom headache, has symptom rash, has symptom chills, and has symptom pneumonia.

MalaCards based summary : Ornithosis, also known as psittacosis, is related to pneumonia and lymphoma, mucosa-associated lymphoid type, and has symptoms including fever, headache and pneumonia. An important gene associated with Ornithosis is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha). The drugs Doxycycline and Azithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and skin.

Wikipedia : 76 Psittacosis�??also known as parrot fever, and ornithosis�??is a zoonotic infectious disease caused by a... more...

Related Diseases for Ornithosis

Diseases related to Ornithosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 pneumonia 10.3
2 lymphoma, mucosa-associated lymphoid type 10.2
3 lymphoma 10.2
4 chlamydia 10.2
5 lymphogranuloma venereum 10.2
6 b-cell lymphomas 10.2
7 chlamydia pneumonia 10.2
8 upper respiratory tract disease 10.2
9 salmonellosis 10.2
10 encephalitis 10.2
11 conjunctivitis 10.1
12 legionnaire disease 10.1
13 legionnaires' disease 10.1
14 legionellosis 10.1
15 myocarditis 10.1
16 influenza 10.1
17 cat-scratch disease 10.0
18 inclusion conjunctivitis 10.0
19 alpha-1-antitrypsin deficiency 10.0
20 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
21 ectopic pregnancy 10.0
22 nodal marginal zone lymphoma 10.0
23 sensorineural hearing loss 10.0
24 endometritis 10.0
25 pelvic inflammatory disease 10.0
26 interstitial nephritis 10.0
27 optic neuritis 10.0
28 uveitis 10.0
29 chronic follicular conjunctivitis 10.0
30 neuritis 10.0
31 avian influenza 10.0
32 infertility 10.0
33 subacute thyroiditis 10.0
34 thyroiditis 10.0
35 keratoconjunctivitis 10.0
36 interstitial keratitis 10.0
37 sudden sensorineural hearing loss 10.0
38 transverse myelitis 10.0
39 acute transverse myelitis 10.0
40 infective endocarditis 9.9
41 disseminated intravascular coagulation 9.9
42 hemopericardium 9.9
43 pericardial effusion 9.9
44 typhoid fever 9.9
45 malaria 9.9
46 arthritis 9.9
47 lymphomatoid granulomatosis 9.9
48 erythema multiforme 9.9
49 endocarditis 9.9
50 q fever 9.9

Graphical network of the top 20 diseases related to Ornithosis:



Diseases related to Ornithosis

Symptoms & Phenotypes for Ornithosis

Symptoms:

12
  • fever
  • headache
  • pneumonia
  • chills
  • rash

Drugs & Therapeutics for Ornithosis

Drugs for Ornithosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
2
Azithromycin Approved Phase 2 83905-01-5 55185 447043
3
Rifabutin Approved, Investigational Phase 2 72559-06-9 6323490
4 Anti-Infective Agents Phase 2
5 Antibiotics, Antitubercular Phase 2
6 Antiparasitic Agents Phase 2
7 Anti-Bacterial Agents Phase 2
8 Antiprotozoal Agents Phase 2
9 Antitubercular Agents Phase 2
10 Antimalarials Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease Recruiting NCT03618108 Phase 2 Doxycycline Capsule;Azithromycin Capsule;Rifabutin Oral Capsule;Placebo oral capsule;Placebo Oral Tablet;Placebo oral capsule
2 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
3 Prospective Study of Frontline H Pylori Eradication in the Treatment of Early-stage Extragastric MALT Lymphoma Recruiting NCT02987127

Search NIH Clinical Center for Ornithosis

Cochrane evidence based reviews: psittacosis

Genetic Tests for Ornithosis

Anatomical Context for Ornithosis

MalaCards organs/tissues related to Ornithosis:

41
Testes, Lung, Skin, Brain, Heart, Thyroid, B Cells

Publications for Ornithosis

Articles related to Ornithosis:

(show top 50) (show all 822)
# Title Authors Year
1
Disease burden of psittacosis in the Netherlands. ( 29361998 )
2018
2
An unusual presentation of a case of human psittacosis. ( 29719801 )
2018
3
A Psittacosis Outbreak among English Office Workers with Little or No Contact with Birds, August 2015. ( 29854568 )
2018
4
Wild and domestic bird faeces likely source of psittacosis transmission-A case-control study in Sweden, 2014-2016. ( 29984469 )
2018
5
Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue. ( 30151406 )
2018
6
Laboratory methods for case finding in human psittacosis outbreaks: a systematic review. ( 30165831 )
2018
7
Epidemiological and molecular characteristics of Chlamydia psittaci from 8 human cases of psittacosis and 4 related birds in Argentina. ( 28734713 )
2017
8
Compendium of Measures to Control Chlamydia psittaci Infection Among Humans (Psittacosis) and Pet Birds (Avian Chlamydiosis), 2017. ( 28891690 )
2017
9
Multilocus sequence typing identifies an avian-like Chlamydia psittaci strain involved in equine placentitis and associated with subsequent human psittacosis. ( 28196971 )
2017
10
Intersectoral action for health: preventing psittacosis spread after one reported case. ( 28554339 )
2017
11
An outbreak of psittacosis at a veterinary school demonstrating a novel source of infection. ( 28616500 )
2017
12
Temporal and spatial analysis of psittacosis in association with poultry farming in the Netherlands, 2000-2015. ( 28747153 )
2017
13
Managing a cluster outbreak of psittacosis in Belgium linked to a pet shop visit in The Netherlands. ( 26669637 )
2016
14
Psittacosis: Rare Respiratory Problem in Children. ( 27539767 )
2016
15
Investigation and management of psittacosis in a public aviary: A One Health approach. ( 29770013 )
2016
16
Typing of Chlamydia psittaci to monitor epidemiology of psittacosis and aid disease control in the Netherlands, 2008 to 2013. ( 25677053 )
2015
17
Outbreak of psittacosis in a group of women exposed to Chlamydia psittaci-infected chickens. ( 26111240 )
2015
18
Clinical features of endemic community-acquired psittacosis. ( 25356332 )
2014
19
Multiple human-to-human transmission from a severe case of psittacosis, Sweden, January-February 2013. ( 25358043 )
2014
20
A novel psittacine adenovirus identified during an outbreak of avian chlamydiosis and human psittacosis: zoonosis associated with virus-bacterium coinfection in birds. ( 25474263 )
2014
21
Risk exposures for human ornithosis in a poultry processing plant modified by use of personal protective equipment: an analytical outbreak study. ( 23176790 )
2013
22
Family outbreak of psittacosis with an exhumation-based diagnosis: following in the footsteps of Dr. House. ( 23187301 )
2013
23
First report of human psittacosis in Vietnam. ( 23228501 )
2013
24
Unusual increase of psittacosis in southern Sweden linked to wild bird exposure, January to April 2013. ( 23725809 )
2013
25
Zoonotic atypical pneumonia due to Chlamydophila psittaci: first reported psittacosis case in Taiwan. ( 23927984 )
2013
26
Psittacosis outbreak in Tayside, Scotland, December 2011 to February 2012. ( 22687915 )
2012
27
Psittacosis infection and tracheobronchomalacia in a patient undergoing thyroidectomy. ( 22675091 )
2011
28
A case of acute psittacosis with severe abdominal pain. ( 21212142 )
2011
29
Psittacosis outbreak after participation in a bird fair, Western France, December 2008. ( 21396150 )
2011
30
Psittacosis. ( 20171542 )
2010
31
Chlamydial infections in duck farms associated with human cases of psittacosis in France. ( 18947944 )
2009
32
Psittacosis presenting as a halo sign on high-resolution computed tomography. ( 19465839 )
2009
33
An outbreak of psittacosis in a bird park in Japan. ( 17559693 )
2008
34
Chlamydophila psittaci infections in humans during an outbreak of psittacosis from poultry in Germany. ( 18387139 )
2008
35
Local newspaper as a diagnostic aid for psittacosis: a case report. ( 18540809 )
2008
36
Familial outbreak of psittacosis as the first Chlamydia psittaci infection reported from Turkey. ( 18701984 )
2008
37
Two fatal cases of psittacosis caused by Chlamydophila psittaci. ( 18809562 )
2008
38
Multiple sites of exposure in an outbreak of ornithosis in workers at a poultry abattoir and farm. ( 17274860 )
2007
39
A fatal case of psittacosis in Slovakia, January 2006. ( 17880885 )
2007
40
Local cluster of psittacosis after bird show in the Netherlands, November 2007. ( 18082112 )
2007
41
A case of fulminant psittacosis. ( 16536718 )
2006
42
Sepsis due to gestational psittacosis: A multidisciplinary approach within a perinatological center--review of reported cases. ( 16596904 )
2006
43
An outbreak of psittacosis due to Chlamydophila psittaci genotype A in a veterinary teaching hospital. ( 17030918 )
2006
44
Psittacosis in all four members of a family in Nagasaki, Japan. ( 17060709 )
2006
45
Compendium of measures to control Chlamydophila psittaci (formerly Chlamydia psittaci) infection among humans (psittacosis) and pet birds, 2005. ( 15742693 )
2005
46
Probable psittacosis outbreak linked to wild birds. ( 15757553 )
2005
47
A woman with a lobar infiltrate due to psittacosis detected by polymerase chain reaction. ( 12953962 )
2003
48
Familial cases of psittacosis: possible person-to-person transmission. ( 12132529 )
2002
49
Psittacosis/avian chlamydiosis. ( 12494967 )
2002
50
Psittacosis. A flu like syndrome. ( 11681143 )
2001

Variations for Ornithosis

Expression for Ornithosis

Search GEO for disease gene expression data for Ornithosis.

Pathways for Ornithosis

GO Terms for Ornithosis

Molecular functions related to Ornithosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatidylinositol binding GO:0035091 8.62 NCF4 PIK3C2A

Sources for Ornithosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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