MCID: ORN001
MIFTS: 39

Ornithosis

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Ornithosis

MalaCards integrated aliases for Ornithosis:

Name: Ornithosis 12 74 52 15 17
Psittacosis 12 74 52 54 3 43 71
Chlamydial Pneumonia 52 71 32
Chlamydia Psittaci Infection 71 32
Chlamydia Psittaci 52

Classifications:



External Ids:

Disease Ontology 12 DOID:11262
ICD9CM 34 073 073.9
MeSH 43 D009956
NCIt 49 C34873
SNOMED-CT 67 75116005
ICD10 32 A70 J16.0
UMLS 71 C0029291 C0276108 C0339959

Summaries for Ornithosis

CDC : 3 Chlamydia psittaci is a type of bacteria that often infects birds. Less commonly, these bacteria can infect people and cause a disease called psittacosis. Psittacosis causes a wide range of symptoms, including fever, headache, and a dry cough. This illness can also cause pneumonia (a lung infection) that may require treatment or care in a hospital. Rarely, psittacosis can be deadly.

MalaCards based summary : Ornithosis, also known as psittacosis, is related to lymphogranuloma venereum and legionnaire disease, and has symptoms including fever, headache and pneumonia. An important gene associated with Ornithosis is PIK3C2A (Phosphatidylinositol-4-Phosphate 3-Kinase Catalytic Subunit Type 2 Alpha). The drugs Azithromycin and Rifabutin have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and thyroid, and related phenotype is cellular.

Disease Ontology : 12 A primary bacterial infectious disease that results in systemic infection, has material basis in Chlamydia psittaci, which is transmitted by inhaling aerosolized dried droppings or transmitted by contact with infected birds. The infection has symptom fever, has symptom headache, has symptom rash, has symptom chills, and has symptom pneumonia.

Wikipedia : 74 Psittacosis-also known as parrot fever, and ornithosis-is a zoonotic infectious disease in humans caused... more...

Related Diseases for Ornithosis

Diseases related to Ornithosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 238)
# Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 30.7 NAT9 ESCO2 ALLC
2 legionnaire disease 30.5 PIK3C2A CD40LG
3 marginal zone b-cell lymphoma 30.5 KDM4C CD40LG
4 leptospirosis 30.4 PIK3C2A CD40LG
5 inclusion conjunctivitis 30.2 NAT9 ESCO2 CD40LG
6 pericardial effusion 30.2 PIK3C2A CD40LG
7 salpingitis 30.1 NAT9 ESCO2 CD40LG
8 pelvic inflammatory disease 30.1 NAT9 ESCO2 CD40LG
9 urethritis 30.0 NAT9 ESCO2 CD40LG
10 exanthem 29.8 PIK3C2A CD40LG
11 lymphoma 10.7
12 pneumonia 10.7
13 chlamydia 10.6
14 keratoconjunctivitis 10.5
15 lymphoma, mucosa-associated lymphoid type 10.5
16 encephalitis 10.5
17 q fever 10.4
18 rhinitis 10.4
19 salmonellosis 10.4
20 trachoma 10.4
21 chlamydia pneumonia 10.4
22 infertility 10.3
23 eye disease 10.3
24 cervicitis 10.3 NAT9 ESCO2
25 gas gangrene 10.3 PIK3C2A ALLC
26 orbital plasma cell granuloma 10.3 PIK3C2A CD40LG
27 alkhurma hemorrhagic fever 10.3 PIK3C2A CD40LG
28 trichinosis 10.3 PIK3C2A CD40LG
29 chronic conjunctivitis 10.3
30 vaginal discharge 10.3
31 upper respiratory tract disease 10.3
32 rapidly involuting congenital hemangioma 10.3
33 argyria 10.3
34 hairy tongue 10.3 PIK3C2A CD40LG
35 conjunctivitis 10.2
36 myocarditis 10.2
37 ross river fever 10.2 NAT9 CD40LG
38 anuria 10.2 PIK3C2A CD40LG
39 bacterial conjunctivitis 10.2 NAT9 CD40LG
40 erysipelas 10.2 PIK3C2A CD40LG
41 childhood type dermatomyositis 10.2 PIK3C2A CD40LG
42 miller fisher syndrome 10.2 CD40LG ALLC
43 epididymis disease 10.2 NAT9 CD40LG
44 headache 10.2
45 fungal meningitis 10.2 CD40LG ALLC
46 autoimmune disease of peripheral nervous system 10.2 CD40LG ALLC
47 acute kidney tubular necrosis 10.2 PIK3C2A CD40LG
48 aspiration pneumonia 10.2 PIK3C2A CD40LG
49 chlorpropamide-alcohol flushing 10.2
50 longevity 2 10.2

Graphical network of the top 20 diseases related to Ornithosis:



Diseases related to Ornithosis

Symptoms & Phenotypes for Ornithosis

Symptoms:

12
  • fever
  • headache
  • pneumonia
  • chills
  • rash

MGI Mouse Phenotypes related to Ornithosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.23 CD40LG CREG1 ESCO2 KDM4C PIK3C2A SNAPIN

Drugs & Therapeutics for Ornithosis

Drugs for Ornithosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 2 83905-01-5 55185 447043
2
Rifabutin Approved, Investigational Phase 2 72559-06-9 6323490 46783538
3
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
4
Permethrin Approved, Investigational Phase 2 52645-53-1 40326
5 Anti-Infective Agents Phase 2
6 Antitubercular Agents Phase 2
7 Anti-Bacterial Agents Phase 2
8 Antibiotics, Antitubercular Phase 2
9 Antimalarials Phase 2
10 Antiprotozoal Agents Phase 2
11 Antiparasitic Agents Phase 2
12 Insect Repellents Phase 2
13 Protective Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase IIa Prospective Study to Evaluate the Safety and Measure Efficacy of Anti-chlamydophila Antibiotic Combination (ACAC) Therapy Comprising 100mg Doxycycline, 500mg Azithromycin and 300mg Rifabutin in the Treatment of Patients With Coronary Heart Disease (CHD) Recruiting NCT03618108 Phase 2 Doxycycline Capsule;Azithromycin Capsule;Rifabutin Oral Capsule;Placebo oral capsule;Placebo Oral Tablet;Placebo oral capsule
2 A Within-subject Laboratory and Field Trial to Test the Use of Commercially Available Insect Repellents Against Contact From Musca Sorbens, the Putative Vector of Trachoma Suspended NCT03813069 Phase 2
3 Prospective Study of Frontline Helicobacter Pylori Eradication Therapy in the Treatment of Early-stage Extragastric Mucosa-associated Lymphoid Tissue Lymphoma Unknown status NCT02987127
4 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952

Search NIH Clinical Center for Ornithosis

Cochrane evidence based reviews: psittacosis

Genetic Tests for Ornithosis

Anatomical Context for Ornithosis

MalaCards organs/tissues related to Ornithosis:

40
Testes, Lung, Thyroid, Heart, Skin, Eye, Kidney

Publications for Ornithosis

Articles related to Ornithosis:

(show top 50) (show all 1934)
# Title Authors PMID Year
1
[Two cases of psittacosis accompanied with rhabdomyolysis]. 54 61
2243196 1990
2
Recent history of psittacosis in Australia: expanding our understanding of the epidemiology of this important globally distributed zoonotic disease. 61
32037712 2020
3
Human psittacosis: a review with emphasis on surveillance in Belgium. 61
30882289 2020
4
SURVEILLANCE FOR CHLAMYDIA SPP. WITH MULTILOCUS SEQUENCE TYPING ANALYSIS IN WILD AND CAPTIVE BIRDS IN VICTORIA, AUSTRALIA. 61
31329521 2020
5
Timeliness of infectious disease reporting, the Netherlands, 2003 to 2017: law change reduced reporting delay, disease identification delay is next. 61
31822327 2019
6
Psittacosis Outbreak among Workers at Chicken Slaughter Plants, Virginia and Georgia, USA, 2018. 61
31625859 2019
7
A parrot-type Chlamydia psittaci strain is in association with egg production drop in laying ducks. 61
31127977 2019
8
Case report: Possible psittacosis in a military family member-clinical and public health management issues in military settings. 61
31347370 2019
9
A Bird's-Eye View of Chronic Unilateral Conjunctivitis: Remember about Chlamydia psittaci. 61
31052181 2019
10
Isolation and Characterization of Avian Chlamydia psittaci from Symptomatic Pet Birds in Southern Hunan, China. 61
31251517 2019
11
[Features distinguishing ornithosis from avian acute hypersensitivity pneumonitis - a retrospective analysis]. 61
30473450 2019
12
Customs officers in relation to viral infections, tuberculosis, psittacosis and environmental health risk. 61
30679987 2019
13
[Human Psittacosis: A Case Report]. 61
30896398 2019
14
Simultaneous Intramuscular And Intranasal Administration Of Chitosan Nanoparticles-Adjuvanted Chlamydia Vaccine Elicits Elevated Protective Responses In The Lung. 61
31632026 2019
15
[Laboratory diagnosis of rare diseases]. 61
30480747 2018
16
Wild and domestic bird faeces likely source of psittacosis transmission-A case-control study in Sweden, 2014-2016. 61
29984469 2018
17
Chlamydophila psittaci pneumonia associated to exposure to fulmar birds (Fulmaris glacialis) in the Faroe Islands. 61
30241455 2018
18
[Psittacosis - a forgotten diagnosis in Sweden?] 61
30480746 2018
19
Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue. 61
30151406 2018
20
Virulence-related comparative transcriptomics of infectious and non-infectious chlamydial particles. 61
30068313 2018
21
Laboratory methods for case finding in human psittacosis outbreaks: a systematic review. 61
30165831 2018
22
Molecular evidence to suggest pigeon-type Chlamydia psittaci in association with an equine foal loss. 61
29352509 2018
23
Chlamydiosis in farmed chickens in Slovakia and zoonotic risk for humans. 61
29936804 2018
24
Veterinary Students' Knowledge and Perceptions About Antimicrobial Stewardship and Biosecurity-A National Survey. 61
29670064 2018
25
A Psittacosis Outbreak among English Office Workers with Little or No Contact with Birds, August 2015. 61
29854568 2018
26
Equine chlamydiosis-An emerging infectious disease requiring a one health surveillance approach. 61
28984040 2018
27
Disease burden of psittacosis in the Netherlands. 61
29361998 2018
28
Chlamydia Persistence: A Survival Strategy to Evade Antimicrobial Effects in-vitro and in-vivo. 61
30619180 2018
29
An unusual presentation of a case of human psittacosis. 61
29719801 2018
30
Seroprevalence of Chlamydophila Psittaci among Employees of Two German Duck Farms. 61
29403654 2017
31
Chlamydia psittaci (psittacosis) as a cause of community-acquired pneumonia: a systematic review and meta-analysis. 61
28946931 2017
32
Transcription of seven genes in a model of interferon‑γ-induced persistent Chlamydia psittaci infection. 61
28765948 2017
33
Epidemiological and molecular characteristics of Chlamydia psittaci from 8 human cases of psittacosis and 4 related birds in Argentina. 61
28734713 2017
34
The role of zoonotic chlamydial agents in ruminants abortion. 61
29296274 2017
35
Compendium of Measures to Control Chlamydia psittaci Infection Among Humans (Psittacosis) and Pet Birds (Avian Chlamydiosis), 2017. 61
28891690 2017
36
Intersectoral action for health: preventing psittacosis spread after one reported case. 61
28554339 2017
37
Temporal and spatial analysis of psittacosis in association with poultry farming in the Netherlands, 2000-2015. 61
28747153 2017
38
An outbreak of psittacosis at a veterinary school demonstrating a novel source of infection. 61
28616500 2017
39
Hypercalcemia in children: three cases report with unusual clinical presentations. 61
29069246 2017
40
Persistence of Chlamydia psittaci in Various Temperatures and Times. 61
28301242 2017
41
Legionnaire's Disease and its Mimics: A Clinical Perspective. 61
28159179 2017
42
Multilocus sequence typing identifies an avian-like Chlamydia psittaci strain involved in equine placentitis and associated with subsequent human psittacosis. 61
28196971 2017
43
Chlamydia-host cell interaction not only from a bird's eye view: some lessons from Chlamydia psittaci. 61
27397851 2016
44
Birds of a feather: an uncommon cause of pneumonia and meningoencephalitis. 61
27620382 2016
45
Psittacosis: Rare Respiratory Problem in Children. 61
27539767 2016
46
Bacterial Zoonoses Transmitted by Household Pets: State-of-the-Art and Future Perspectives for Targeted Research and Policy Actions. 61
25958184 2016
47
Managing a cluster outbreak of psittacosis in Belgium linked to a pet shop visit in The Netherlands. 61
26669637 2016
48
Investigation and management of psittacosis in a public aviary: A One Health approach. 61
29770013 2016
49
'Tipping the Balance': Karl Friedrich Meyer, Latent Infections, and the Birth of Modern Ideas of Disease Ecology. 61
26612760 2016
50
Chlamydia psittaci: a relevant cause of community-acquired pneumonia in two Dutch hospitals. 61
26951352 2016

Variations for Ornithosis

Expression for Ornithosis

Search GEO for disease gene expression data for Ornithosis.

Pathways for Ornithosis

GO Terms for Ornithosis

Sources for Ornithosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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