MCID: ORP001
MIFTS: 16

Oropharyngeal Anthrax

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Oropharyngeal Anthrax

MalaCards integrated aliases for Oropharyngeal Anthrax:

Name: Oropharyngeal Anthrax 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050059

Summaries for Oropharyngeal Anthrax

Disease Ontology : 12 A gastrointestinal anthrax that results in infection located in mucosa of oropharynx, has material basis in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.

MalaCards based summary : Oropharyngeal Anthrax is related to anthrax disease and cutaneous anthrax. An important gene associated with Oropharyngeal Anthrax is ANTXR2 (ANTXR Cell Adhesion Molecule 2), and among its related pathways/superpathways are NOD-like receptor signaling pathway and Uptake and actions of bacterial toxins. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Oropharyngeal Anthrax

Diseases related to Oropharyngeal Anthrax via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 anthrax disease 30.1 ANTXR2 ANTXR1
2 cutaneous anthrax 29.9 ANTXR2 ANTXR1
3 inhalation anthrax 9.9 ANTXR2 ANTXR1
4 gingival hypertrophy 9.9 ANTXR2 ANTXR1
5 hydrops, lactic acidosis, and sideroblastic anemia 9.9 ANTXR2 ANTXR1
6 winchester syndrome 9.9 ANTXR2 ANTXR1
7 hyaline fibromatosis syndrome 9.7 ANTXR2 ANTXR1
8 gastrointestinal anthrax 9.4 EXOC6 ARAP3 ANTXR2 ANTXR1

Graphical network of the top 20 diseases related to Oropharyngeal Anthrax:



Diseases related to Oropharyngeal Anthrax

Symptoms & Phenotypes for Oropharyngeal Anthrax

GenomeRNAi Phenotypes related to Oropharyngeal Anthrax according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.32 ANTXR2
2 Increased shRNA abundance (Z-score > 2) GR00366-A-145 9.32 ANTXR1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.32 ANTXR1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-213 9.32 ANTXR2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.32 ANTXR1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-216 9.32 ANTXR2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-53 9.32 ANTXR2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-55 9.32 ANTXR2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.32 ANTXR1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-81 9.32 ANTXR2

MGI Mouse Phenotypes related to Oropharyngeal Anthrax:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.02 ANTXR1 ANTXR2 EXOC6 MTSS1 RTCB

Drugs & Therapeutics for Oropharyngeal Anthrax

Search Clinical Trials , NIH Clinical Center for Oropharyngeal Anthrax

Genetic Tests for Oropharyngeal Anthrax

Anatomical Context for Oropharyngeal Anthrax

Publications for Oropharyngeal Anthrax

Articles related to Oropharyngeal Anthrax:

# Title Authors PMID Year
1
Anthrax of the gastrointestinal tract. 61
12095428 2002
2
Clinical aspects, diagnosis and treatment of anthrax 61
10475974 1999
3
[Oropharyngeal anthrax]. 61
8369089 1993
4
Serological studies of patients with cutaneous and oral-oropharyngeal anthrax from northern Thailand. 61
3144920 1988
5
Oropharyngeal anthrax. 61
3934300 1985
6
Outbreak of oral-oropharyngeal anthrax: an unusual manifestation of human infection with Bacillus anthracis. 61
6696173 1984

Variations for Oropharyngeal Anthrax

Expression for Oropharyngeal Anthrax

Search GEO for disease gene expression data for Oropharyngeal Anthrax.

Pathways for Oropharyngeal Anthrax

GO Terms for Oropharyngeal Anthrax

Cellular components related to Oropharyngeal Anthrax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ruffle GO:0001726 8.62 MTSS1 ARAP3

Biological processes related to Oropharyngeal Anthrax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 toxin transport GO:1901998 8.62 ANTXR2 ANTXR1

Sources for Oropharyngeal Anthrax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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