MCID: ORT001
MIFTS: 26

Orthostatic Proteinuria

Categories: Nephrological diseases

Aliases & Classifications for Orthostatic Proteinuria

MalaCards integrated aliases for Orthostatic Proteinuria:

Name: Orthostatic Proteinuria 12 15 71
Postural Albuminuria 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9617
ICD9CM 34 593.6
ICD10 32 N39.2 R80.2
UMLS 71 C0232867

Summaries for Orthostatic Proteinuria

MalaCards based summary : Orthostatic Proteinuria, also known as postural albuminuria, is related to glomerular disease and iga glomerulonephritis. An important gene associated with Orthostatic Proteinuria is ALB (Albumin), and among its related pathways/superpathways is A-beta Pathways: Plaque Formation and APP Metabolism. Affiliated tissues include kidney, heart and liver, and related phenotype is cardiovascular system.

Related Diseases for Orthostatic Proteinuria

Diseases related to Orthostatic Proteinuria via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
# Related Disease Score Top Affiliating Genes
1 glomerular disease 30.1 ALB ACE
2 iga glomerulonephritis 29.2 REN ALB ACE
3 renal nutcracker syndrome 11.6
4 diabetes mellitus, ketosis-prone 10.3 INSM2 ALB
5 nephrotic syndrome 10.2
6 idiopathic nephrotic syndrome 10.1 ALB ACE
7 granulomatous hepatitis 10.1 ALB ACE
8 constrictive pericarditis 10.1 ALB ACE
9 pericarditis 10.1 ALB ACE
10 cranial nerve palsy 10.1 ALB ACE
11 background diabetic retinopathy 10.1 ALB ACE
12 hypersensitivity vasculitis 10.1 ALB ACE
13 papilledema 10.1 ALB ACE
14 facial paralysis 10.1 ALB ACE
15 facial nerve disease 10.1 ALB ACE
16 hypersensitivity reaction type iii disease 10.1 ALB ACE
17 ptosis 10.1
18 glomerulonephritis 10.1
19 tricuspid valve insufficiency 10.1 ALB ACE
20 drug allergy 10.1 ALB ACE
21 macular retinal edema 10.1 ALB ACE
22 tricuspid valve disease 10.1 ALB ACE
23 maturity-onset diabetes of the young, type 1 10.1 ALB ACE
24 aspiration pneumonia 10.1 ALB ACE
25 pulmonary artery disease 10.1 ALB ACE
26 acute pyelonephritis 10.0 ALB ACE
27 endocardium disease 10.0 ALB ACE
28 sexual disorder 10.0 ALB ACE
29 hemorrhage, intracerebral 10.0 CST3 ACE
30 plague 10.0 WARS1 ALB
31 prediabetes syndrome 10.0 ALB ACE
32 rheumatic fever 10.0 ALB ACE
33 polycystic kidney disease 4 10.0 REN ALB
34 syphilis 10.0 ALB ACE
35 bartonellosis 10.0 WARS1 ACE
36 inappropriate adh syndrome 10.0 REN ALB
37 benign essential hypertension 10.0 REN ALB
38 arteriolosclerosis 10.0 REN ALB
39 intermittent claudication 10.0 ALB ACE
40 testicular torsion 9.9
41 creatinine clearance quantitative trait locus 9.9
42 inflammatory bowel disease 9.9
43 varicocele 9.9
44 focal segmental glomerulosclerosis 9.9
45 purpura 9.9
46 liver disease 9.9
47 47,xyy 9.9
48 renal artery atheroma 9.9 REN CST3
49 exanthem 9.9 ALB ACE
50 systolic heart failure 9.9 CST3 ACE

Graphical network of the top 20 diseases related to Orthostatic Proteinuria:



Diseases related to Orthostatic Proteinuria

Symptoms & Phenotypes for Orthostatic Proteinuria

MGI Mouse Phenotypes related to Orthostatic Proteinuria:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.1 ACE ALB CST3 REN STRIP1 WARS1

Drugs & Therapeutics for Orthostatic Proteinuria

Search Clinical Trials , NIH Clinical Center for Orthostatic Proteinuria

Genetic Tests for Orthostatic Proteinuria

Anatomical Context for Orthostatic Proteinuria

MalaCards organs/tissues related to Orthostatic Proteinuria:

40
Kidney, Heart, Liver, Pancreas

Publications for Orthostatic Proteinuria

Articles related to Orthostatic Proteinuria:

(show top 50) (show all 115)
# Title Authors PMID Year
1
A case report of a young girl with recurrent hematuria: a missed diagnosis - renal nutcracker syndrome. 61
31488074 2019
2
High prevalence of underlying orthostatic proteinuria in young Japanese women. 61
30834612 2019
3
Simplified Algorithm for Evaluation of Proteinuria in Clinical Practice: How should A Clinician Approach? 61
30967921 2019
4
Orthostatic proteinuria due to smartphone use in bed. 61
30920105 2018
5
Nutcracker Syndrome in Children: Role of Doppler Ultrasonographic Indices in Detecting the Pattern of Symptoms. 61
30104539 2018
6
Urinary fibrin/fibrinogen degradation products measured using an anti-fibrinogen antibody predict orthostatic proteinuria. 61
29654610 2018
7
Nutcracker syndrome in adolescent with perineal pain: An interesting case of an adolescent with perineal pain due to pelvic congestion from nutcracker syndrome with relief after balloon venoplasty and sclerotherapy. 61
29487651 2018
8
Nutcracker syndrome: A rare cause of left flank pain that can also manifest as unexplained pelvic pain. 61
27932281 2017
9
Proteinuria in Children: Evaluation and Differential Diagnosis. 61
28290633 2017
10
Nutcracker syndrome. 61
25374822 2014
11
[Nutcracker syndrome: Cause of non-glomerular hematuria and massive proteinuria]. 61
29421619 2014
12
Urinalysis in children and adolescents. 61
25283761 2014
13
Adult orthostatic proteinuria. 61
25852903 2014
14
Clinical course of children with nutcracker syndrome. 61
23735609 2013
15
Endovascular stent placement for the treatment of nutcracker syndrome. 61
22086468 2012
16
Pediatric left renal vein entrapment syndrome diagnosed by 99mTc-albumin-conjugate scintigraphy. 61
23689519 2012
17
Erich Frank (1884-1957): unsung pioneer in nephrology. 61
21864962 2011
18
[Asymptomatic proteinuria in children]. 61
22028262 2011
19
Left renal venographic findings in children with orthostatic proteinuria. 61
21636825 2011
20
Renal vein obstruction and orthostatic proteinuria: a review. 61
20656752 2011
21
Orthostatic proteinuria: a harmless variant of protein loss? 61
21411841 2011
22
Multidetector computed tomography in orthostatic proteinuria? 61
20386925 2010
23
Proteinuria in children. 61
20842993 2010
24
A rare cause of recurrent hematuria in children: Nutcracker syndrome. 61
20007737 2010
25
[What is your diagnosis? Orthostatic proteinuria]. 61
20737392 2010
26
Orthostatic proteinuria and the spectrum of diurnal variability of urinary protein excretion in healthy children. 61
20165888 2010
27
Nutcracker syndrome in a child with familial Mediterranean fever (FMF) disease: renal ultrastructural features. 61
19031109 2009
28
Diagnosis and surgical treatment of nutcracker syndrome: a single-center experience. 61
19193424 2009
29
Blood pressure load, proteinuria and renal function in pre-hypertensive children. 61
19096881 2009
30
[Efficacy of Enalapril in patients with single kidney and with or without normoprotein diet]. 61
19030641 2008
31
ACE inhibition in nutcracker syndrome with orthostatic proteinuria: how about a hemodynamic effect? 61
17333002 2007
32
ACE inhibition can improve orthostatic proteinuria associated with nutcracker syndrome. 61
16902785 2006
33
Urine proteomic profiling of pediatric nephrotic syndrome. 61
16810512 2006
34
The "nutcracker phenomenon" with orthostatic proteinuria: case reports. 61
16629228 2006
35
Left testicular artery arching over the ipsilateral renal vein. 61
16372128 2006
36
An ultrasonographic classification for diverse clinical symptoms of pediatric nutcracker phenomenon. 61
16047645 2005
37
[Hematuria and proteinuria in childhood]. 61
15790015 2005
38
Role of routine urinalysis in asymptomatic pediatric patients. 61
15678230 2005
39
[Differential diagnosis of proteinuria]. 61
15559519 2004
40
The role of body position and gravity in the symptoms and treatment of various medical diseases. 61
15551157 2004
41
[Orthostatic proteinuria or latent nephritis?]. 61
16136988 2004
42
[Orthostatic proteinuria and compression of the left renal vein (nutcracker syndrome)]. 61
12870396 2003
43
Isolated asymptomatic proteinuria. 61
12557959 2002
44
Nutcracker syndrome in children with orthostatic proteinuria: diagnosis on the basis of Doppler sonography. 61
11794401 2002
45
Diagnosis of nut-cracker phenomenon using renal Doppler ultrasound in orthostatic proteinuria. 61
11477164 2001
46
Proteinuria: potential causes and approach to evaluation. 61
11014373 2000
47
[Proteinuria in children: practical approach]. 61
10815456 2000
48
Does severe nutcracker phenomenon cause pediatric chronic fatigue? 61
10749295 2000
49
Orthostatic proteinuria as a result of venous compression (nutcracker phenomenon)--a hypothesis testable with modern imaging techniques. 61
10328451 1999
50
Evaluating proteinuria in children. 61
9787280 1998

Variations for Orthostatic Proteinuria

Expression for Orthostatic Proteinuria

Search GEO for disease gene expression data for Orthostatic Proteinuria.

Pathways for Orthostatic Proteinuria

Pathways related to Orthostatic Proteinuria according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.98 CST3 ACE

GO Terms for Orthostatic Proteinuria

Biological processes related to Orthostatic Proteinuria according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 amyloid-beta metabolic process GO:0050435 8.96 REN ACE
2 angiotensin maturation GO:0002003 8.62 REN ACE

Sources for Orthostatic Proteinuria

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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