Osgood-Schlatter's Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Osgood-Schlatter's Disease

MalaCards integrated aliases for Osgood-Schlatter's Disease:

Name: Osgood-Schlatter's Disease ¹¹ ¹⁴

Osgood-Schlatter Disease ¹¹ ⁵⁸ ⁷⁵

Juvenile Osteochondrosis of Tibial Tubercle ¹¹ ⁷¹

Osteochondrosis ⁴³ ⁷¹

Aseptic Necrosis of the Tibial Tubercle ⁵⁸

Osteochondrosis of the Tibial Tubercle ⁵⁸

Osteochondritis of Tibial Tubercle ¹¹

Osteochondrosis of Proximal Tibia ¹¹

Osteochondritis Juvenilis ⁷¹

Characteristics:

Age Of Onset:

Osgood-Schlatter Disease: Adolescent,Childhood ⁵⁸

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Bone diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the musculoskeletal system and connective tissue

Chondropathies

Other osteochondropathies

Osteochondritis dissecans

Orphanet: ⁵⁸

Rare systemic and rhumatological diseases

Rare bone diseases

External Ids:

Disease Ontology ¹¹ DOID:7489

MeSH ⁴³ D055034

NCIt ⁴⁹ C34874

SNOMED-CT ⁶⁸ 72047008

ICD10 via Orphanet ³² M93.2

UMLS via Orphanet ⁷² C0029376

Orphanet ⁵⁸ ORPHA97335

SNOMED-CT via HPO ⁶⁹ 228158008 282479002 30989003 more

UMLS ⁷¹ C0029376 C0029429 C0729346

Sources

Summaries for Osgood-Schlatter's Disease

Orphanet: ⁵⁸ Osgood-Schlatter disease is a traction apophysitis of the anterior tibial tubercle described in active adolescents and characterized by gradual onset of pain and swelling of the anterior knee causing limping that usually disappears at the end of growth.

MalaCards based summary: Osgood-Schlatter's Disease, also known as osgood-schlatter disease, is related to scheuermann disease and legg-calve-perthes disease. An important gene associated with Osgood-Schlatter's Disease is RPS13 (Ribosomal Protein S13). The drugs Lidocaine and Anti-Arrhythmia Agents have been mentioned in the context of this disorder. Affiliated tissues include tibia, bone and testis, and related phenotypes are knee pain and irregular proximal tibial epiphyses

Disease Ontology: ¹¹ A bone inflammation disease that involves rupture of the growth plate in children located in tibia.

Wikipedia: ⁷⁵ Osgood-Schlatter disease (OSD) is inflammation of the patellar ligament at the tibial tuberosity... more...

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Related Diseases for Osgood-Schlatter's Disease

Diseases related to Osgood-Schlatter's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 169)

#	Related Disease	Score
1	scheuermann disease	11.6
2	legg-calve-perthes disease	11.5
3	kohler's disease	11.4
4	panner disease	11.3
5	freiberg's disease	11.1
6	osteochondrosis of the metatarsal bone	11.0
7	kienbock's disease	11.0
8	thiemann disease	10.9
9	blount disease, infantile	10.9
10	blount disease, adolescent	10.9
11	osteochondrosis of genetic origin	10.9
12	osteochondrosis	10.7
13	cartilage disease	10.6
14	paine syndrome	10.5
15	osseous heteroplasia, progressive	10.4
16	bursitis	10.4
17	radiculopathy	10.4
18	osteonecrosis	10.4
19	tendinopathy	10.4
20	arthropathy	10.4
21	osteoarthritis	10.4
22	spondylosis	10.3
23	spondylitis	10.3
24	enterocele	10.2
25	periarthritis	10.2
26	bone disease	10.2
27	blount's disease	10.2
28	juxtacortical chondroma	10.2
29	chondroma	10.2
30	osteochondritis dissecans	10.2
31	spinal cord disease	10.2
32	cleft palate, isolated	10.2
33	dysplasia epiphysealis hemimelica	10.2
34	exostoses, multiple, type i	10.2
35	attention deficit-hyperactivity disorder	10.2
36	enchondromatosis, multiple, ollier type	10.2
37	polykaryocytosis inducer	10.2
38	contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a	10.2
39	arts syndrome	10.2
40	astigmatism	10.2
41	tendinosis	10.2
42	stickler syndrome	10.2
43	hypogonadotropic hypogonadism	10.2
44	osteomyelitis	10.2
45	arteriovenous malformation	10.2
46	exostosis	10.2
47	enthesopathy	10.2
48	connective tissue disease	10.2
49	compartment syndrome	10.2
50	muscular atrophy	10.2

Graphical network of the top 20 diseases related to Osgood-Schlatter's Disease:

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Symptoms & Phenotypes for Osgood-Schlatter's Disease

Human phenotypes related to Osgood-Schlatter's Disease:

⁵⁸ ³⁰ (show all 8)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	knee pain ⁵⁸ ³⁰	Hallmark (90%)	Very frequent (99-80%)	HP:0030839
2	irregular proximal tibial epiphyses ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0006456
3	difficulty walking ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0002355
4	abnormal patella morphology ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0003045
5	limited knee extension ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0003066
6	difficulty running ⁵⁸ ³⁰	Frequent (33%)	Frequent (79-30%)	HP:0009046
7	shuffling gait ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0002362
8	large knee ⁵⁸ ³⁰	Occasional (7.5%)	Occasional (29-5%)	HP:0030866

Sources

Drugs & Therapeutics for Osgood-Schlatter's Disease

Drugs for Osgood-Schlatter's Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Lidocaine

Approved, Vet_approved

Phase 1, Phase 2

137-58-6

3676

2

Anti-Arrhythmia Agents

Phase 1, Phase 2

3

Sodium Channel Blockers

Phase 1, Phase 2

4

Anesthetics, Local

Phase 1, Phase 2

5

Anesthetics

Phase 1, Phase 2

6

Diuretics, Potassium Sparing

Phase 1, Phase 2

7

Cholecalciferol

Approved, Nutraceutical, Vet_approved

67-97-0, 1406-16-2

5280795 10883523

Synonyms:

(+)-Vitamin D3

(1S,3Z)-3-[(2E)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol

(1S,3Z)-3-[(2E)-2-[(1R,3AS,7AR)-1-[(1R)-1,5-DIMETHYLHEXYL]-7A-METHYL-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLENE-1-CYCLOHEXANOL

(1S,3Z)-3-[(2E)-2-[(1R,3AS,7AR)-1-[(1R)-1,5-DIMETHYLHEXYL]-7A-METHYL-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLENE-CYCLOHEXAN-1-OL

(1S,3Z)-3-[(2E)-2-[(1R,3AS,7AR)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENECYCLOHEXAN-1-OL

(1S,3Z)-3-[(2E)-2-[(1R,3AS,7AR)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL

(1S,3Z)-3-{2-[(1R,4E,7AR)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-OCTAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE}-4-METHYLIDENECYCLOHEXAN-1-OL

(3 beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

(3BETA,Z,7E)-9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-OL

(3Β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol

(5E,7E)-9,10-SECOCHOLESTA-5,7,10-TRIEN-3-OL

(5Z,7E)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol

3-BETA,Z,7E-9,10-SECOCHOLESTR-5,7,10(19)-TRIEN-3-OL

7-DEHYDROCHOLESTEROL

9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3BETA-OL

9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-BETA-OL

9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-OL

9,10-SECOCHOLESTA-5,7,10-TRIEN-3-OL

ACCRETE D3

ACIFEROL D3

ACTIVATED

Activated 7-dehydrocholesterol

ADCAL-D3

ARACHITOL

AVITICOL

BIOLIFE VITAMIN D3

BIO-VITAMIN D3

CACIT D3

CALCEOS

CALCICHEW D3

CALCICHEW D3 FTE

CALCICHEW D3 ONCE DAILY

CALCI-D

Calciferol

Calciol

CALDRINK D3

CALFOVIT D3

CC

Cholecalciferol

CHOLECALCIFEROL D3

Cholecalciferols

Cholecalciferolum

COLECAL D3

Colecalciferol

Colecalciferolum

COLEKAL-D3

COLEVIT D3

CUBICOLE D3

D3 LEMON MELTS

D3-50

D3-VIGANTOL

DEKRISTOL

DELSTEROL

Delta-D

DEPARAL

DESUNIN

DEVARON

Dihydrocholesterol

DLUX 400

D-MAX

D-TRACETTEN

D-VIT3

EBIVIT

E-D3

EVACAL D3

FERACOL

FULTIUM DAILY D3

FULTIUM-D3

GRANUVIT D3

HUX D3

INVITA D3

ISO D3

KORA LIQUID

MICRO-DEE

NATECAL D3

NATURE'S REMEDY VITAMIN D3

NEO-D

NPHD3

NSC-375571

Oleovitamin D3

OSTEOCAPS D3

PLENACHOL

PRO D3

PRO D3 FOLIC

PRO D3 FORTE

PROVITINA

QUINTOX

RICKETON

ROYALVIT D3

STEXEROL-D3

STIVIT-D3

SUNVIT-D3 1,000

SUNVIT-D3 10,000

SUNVIT-D3 2,000

SUNVIT-D3 20,000

SUNVIT-D3 3,000

SUNVIT-D3 400

SUNVIT-D3 5,000

SUNVIT-D3 50,000

SUNVIT-D3 800

SYNERVIT-D3

THEICAL D-3

THORENS

TRIVITAN

VIDDE-3-HYDROSOL

VI-DE3

VIDEKHOL

VIGANTOL

VIGANTOLETTEN

VIGANTOLETTEN 500

VIGORSAN

VIT D3 STREULI

VITA-D3

VITAMIN D

Vitamin D 3

VITAMIN D ASSAY SYSTEM SUITABILITY

Vitamin D NOS

Vitamin D, unspecified form

Vitamin D3

Vitamin D-3

VITINC DAN-DEE-3

ZYMAD

δ-D

8

Vitamins

9

Calciferol

10

Astragalus

11

Calcium, Dietary

12

Calcium

Nutraceutical

7440-70-2

271

Interventional clinical trials:

(show all 30)

#	Name	Status	NCT ID	Phase	Drugs
1	Phase 3 Study Comparison of Autologous Chondrocyte Implantation Versus Mosaicoplasty	Completed	NCT00560664	Phase 3
2	Phase 2 Study of Dextrose Injection for Sport-Limiting Osgood Schlatter Disease in Adolescents.	Completed	NCT01300754	Phase 1, Phase 2
3	Evaluation of Polymorphisms in the Vitamin D Receptor and Involved in Inflammation Associated With Vertebral Osteochondrosis	Unknown status	NCT04195529
4	Clinical Trial of the Efficacy of Hybrid Systems(Topping Off)in Comparison to the Conventional Spondylodesis in Fusion-surgery in the Lumbal Spine: a Prospective, Randomised Study	Unknown status	NCT01224379
5	An Observational, Prospective, Multicentre Study of Patients With Outerbridge Grade III / IV Chondral and/or Osteochondral Defects of the Knee Treated With Nanofractured Autologous Matrix-induced Chondrogenesis	Unknown status	NCT03625180
6	Outcome of the Knee Osteochonditis Dissecans Patiets in Kuopio University Hospital (1990-2009): A Retropective Analysis	Unknown status	NCT01455987
7	Effect of Activity Modification and Exercises in Young Adolescents With Osgood Schlatter Disease.	Completed	NCT02799394
8	Treatment of the Osgood Schlatter Disease by Immobilization ( Ankle Cruro Resin ) Versus Sporting Rest ( Reference Treatment ) : Randomized Controlled Study	Completed	NCT02824172
9	Treatment for Osgood Schlatter Patients With a Physiotherapy Program "TrOPhy-Study"	Completed	NCT04716608
10	A Prospective Investigation of Osgood Schlatter With 24 Month Follow-up	Completed	NCT03589001
11	Sling Suspension Versus Gym Balls in the Treatment of Juvenile Spinal Osteochondrosis in Adolescent Girls	Completed	NCT03851367
12	Prospective Study of Scheuermann's Kyphosis	Completed	NCT00738309
13	Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects (OCD)	Completed	NCT02423629
14	Follow-Up Study Evaluating the Long-Term Outcomes of ChondroMimetic in the Treatment of Osteochondral Defects (Extension Study of Protocol 0MCM0107)	Completed	NCT03385642
15	Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee: Does it Help? A Clinical and Magnetic Resonance Imaging (MRI) Study.	Completed	NCT02397278		Platelet rich plasma (PRP)
16	Retro Versus Trans Articular Drilling for Juvenile Osteochondritis Dissecans of the Knee: A Multicenter, Randomized Controlled Trial	Completed	NCT01754298
17	Examination and Post-operative Rehabilitation of University Athletes With Osteochondral Lesions of the Knee: A Case Series Report	Completed	NCT03452098
18	A Comparison of Two Different Treatment Approaches for Adolescents With Osgood Schlatter: A Randomized Controlled Superiority Trial (The SOGOOD Trial)	Recruiting	NCT05174182
19	Personalized Spine Study Group (PSSG) Registry of Patients With Personalized Spine Rod Implantation	Recruiting	NCT04601363
20	Study Protocol for a Prospective Observational Study to Evaluate the Clinical and Imaging Results of the Fresh Osteochondral Allograft Transplantation for Osteochondral Knee Lesions	Recruiting	NCT04236492
21	Multicentric Observational Study on the Use of a Human Bone Graft in Osteochondral Defects	Recruiting	NCT03777735
22	A Pilot Study to Evaluate the Efficacy of BioCartilage® Micronized Cartilage Matrix in Microfracture Treatment of Osteochondral Defects of the Talus	Recruiting	NCT03696394
23	The Effect of Rıgıd Brace on Spinopelvic Parameters and GAP Score in Adolescents With Structural Hyperkyphosis	Recruiting	NCT04924556
24	Amount of Correction of Torsional Deformity in Blount's Disease After Coronal Plane Deformity Correction by 8 Plate Hemiepiphysiodesis	Not yet recruiting	NCT05334862
25	Comparison of Facilitatory Kinesiology Taping With Combined Inhibitory and Facilitatory Kinesiology Taping Among University Students With Calf Tightness	Not yet recruiting	NCT05434780
26	A Prospective Trial on the Clinical Efficacy of the Ankle Spacer for the Surgical Treatment of Large, Multiple, Cystic and Secondary or Tertiary Osteochondral Defects of the Talus	Terminated	NCT03303690
27	Evaluation of the ReNu™ Amniotic Suspension Allograft After Marrow Stimulation in the Treatment of Osteochondral Defects	Terminated	NCT03036878
28	A Prospective, Open Label, Multi-centre, Post-marketing Registry on the Use of ChondroMimetic for the Repair of Osteochondral Defects	Terminated	NCT01209390
29	Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee.	Withdrawn	NCT02308358
30	Personalized Spine Study Group Registry	Withdrawn	NCT03843476

Search NIH Clinical Center for Osgood-Schlatter's Disease

Cochrane evidence based reviews: osteochondrosis

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Genetic Tests for Osgood-Schlatter's Disease

Sources

Anatomical Context for Osgood-Schlatter's Disease

Organs/tissues related to Osgood-Schlatter's Disease:

FMA: Tibia

MalaCards : Bone, Testis

Sources

Publications for Osgood-Schlatter's Disease

Articles related to Osgood-Schlatter's Disease:

(show top 50) (show all 346)

#	Title	Authors	PMID	Year
1	The posterior tibial slope and Insall-Salvati index in operative and nonoperative adolescent athletes with Osgood-Schlatter disease. ⁶²	Pan T...Hennrikus WL	35075550	2022
2	Medial Proximal Tibia Physeal Overuse Injury of an Athlete. ⁶²	Kuester VG...Zuelzer WA	35858155	2022
3	The mid-term effect of Osgood-Schlatter disease on knee function in young players from elite soccer academies. ⁶²	Bezuglov E...Morgans R	36413052	2022
4	Basic Differences and Most Common Findings in Ultrasound Examinations of Musculoskeletal System in Children: A Narrative Literature Review. ⁶²	Pobozy T...Kielar M	36292459	2022
5	Hyperosmolar dextrose injection for Osgood-Schlatter disease: a double-blind, randomized controlled trial. ⁶²	Wu Z...Tu Z	34673998	2022
6	Describing Frequencies of Lower-Limb Apophyseal Injuries in Children and Adolescents: A Systematic Review. ⁶²	Haines M...Williams CM	34009802	2022
7	Analgesic use in adolescents with patellofemoral pain or Osgood-Schlatter Disease: a secondary cross-sectional analysis of 323 subjects. ⁶²	Andreucci A...Rathleff MS	34860477	2022
8	The German version of the KOOS-Child questionnaire (Knee injury and Osteoarthritis Outcome Score for children) shows a good to excellent internal consistency and a high test-retest reliability in children with knee problems. ⁶²	Neuhaus C...Faude O	35907029	2022
9	Running-related injuries in middle school cross-country runners: Prevalence and characteristics of common injuries. ⁶²	Wu AC...Tenforde AS	34053194	2022
10	Biological Bone Plate and Iliac Bone Autograft for Proximal Tibial Slope Changing Osteotomy in Genu Recurvatum. ⁶²	Zein AMN...Saleh Elsaid AN	35782834	2022
11	The Etiology and Risk Factors of Osgood-Schlatter Disease: A Systematic Review. ⁶²	Lucenti L...Pavone V	35740763	2022
12	Bursoscopic Ultrasound-Guided Ossicle Resection for Osgood-Schlatter Disease. ⁶²	Fujita K...Tsuchiya H	35646559	2022
13	Arthroscopic Resection of Symptomatic Tibial Tubercle Ossicles for Recalcitrant Osgood-Schlatter Disease Using a 2-Portal Technique. ⁶²	McDonough GR...Rossi MJ	35646564	2022
14	Osgood-Schlatter Disease: Appearance, Diagnosis and Treatment: A Narrative Review. ⁶²	Corbi F...Lopez-Laval I	35742062	2022
15	Osgood-Schlatter Disease in youth elite football: Minimal time-loss and no association with clinical and ultrasonographic factors. ⁶²	Schultz M...Reurink G	35305497	2022
16	Incidence and management of Osgood-Schlatter disease in general practice: retrospective cohort study. ⁶²	van Leeuwen GJ...van Middelkoop M	34990396	2022
17	Deep Infrapatellar Bursitis in Preadolescent Baseball Players: A Cross-Sectional Study. ⁶²	Omae H...Chikuda H	35321209	2022
18	Characteristics of the Kicking Motion in Adolescent Male Soccer Players Who Develop Osgood-Schlatter Disease: A Prospective Study. ⁶²	Takei S...Tanaka S	35309237	2022
19	The Osgood-Schlatter disease: a large clinical series with evaluation of risk factors, natural course, and outcomes. ⁶²	Gaulrapp H...Nuhrenborger C	34427770	2022
20	The Biomechanics Effect of Hamstring Flexibility on the Risk of Osgood-Schlatter Disease. ⁶²	Zhang X...Pu F	35586681	2022
21	Osteochondroma of the Tibial Tubercle Masquerading as Osgood-Shlatter Disease: A Case Report. ⁶²	Agaronnik ND...Hogue GD	35991755	2022
22	Therapeutic interventions in Osgood-Schlatter disease: A case report. ⁶²	Gawel E...Zwierzchowska A	34918694	2021
23	[Medical assessment in the field of Social Act VII: pre-existing damage and causality of apophyseal injuries and detachments]. ⁶²	Fernandez Fernandez F...Dresing K	34648057	2021
24	Muscle stiffness of the rectus femoris and vastus lateralis in children with Osgood-Schlatter disease. ⁶²	Enomoto S...Kaga M	34507092	2021
25	Is the Prognosis of Osgood-Schlatter Poorer Than Anticipated? A Prospective Cohort Study With 24-Month Follow-up. ⁶²	Holden S...Rathleff MS	34435066	2021
26	Prevalence of lateral patellofemoral maltracking and associated complications in patients with Osgood Schlatter disease. ⁶²	Kamel SI...Desai V	33404668	2021
27	Posterior Tibial Slope is Increased in Patients With Tibial Tubercle Fractures and Osgood-Schlatter Disease. ⁶²	Sheppard ED...Martin BD	33782370	2021
28	Nano-Arthroscopic Ultrasound-Guided Excision of Unresolved Osgood-Schlatter Disease. ⁶²	Kamiya T...Yamashita T	34258207	2021
29	A systematic review on conservative treatment options for OSGOOD-Schlatter disease. ⁶²	Neuhaus C...Faude O	33744766	2021
30	Osgood-Schlatter Disease as a Possible Cause of Tibial Tuberosity Avulsion. ⁶²	Carius BM...Long B	33728197	2021
31	Tibial tubercle fractures in children and adolescents: a large retrospective case series. ⁶²	Haber DB...Kocher MS	32694426	2021
32	A History of Eponyms in Traction Apophysitises. ⁶²	Bi AS...Castaneda PG	34605759	2021
33	Surgical Treatment Outcomes of Unresolved Osgood-Schlatter Disease in Adolescent Athletes. ⁶²	Mun F...Hennrikus WL	33815856	2021
34	Overuse Knee Pain in the Pediatric and Adolescent Athlete. ⁶²	Sweeney E...MacDonald J	33156034	2020
35	Current management strategies in Osgood Schlatter: A cross-sectional mixed-method study. ⁶²	Lyng KD...Holden S	32562293	2020
36	Simultaneous Bilateral Patellar Tendon Rupture in a Young Adult Male: A Case Report and Review of the Literature. ⁶²	Moy A...Torres D	33133819	2020
37	Conservative treatment of Osgood-Schlatter disease among young professional soccer players. ⁶²	Bezuglov EN...Usmanova EM	32346752	2020
38	Separating the myths from facts: time to take another look at Osgood-Schlatter 'disease'. ⁶²	Holden S...Rathleff MS	31892535	2020
39	Chondroblastoma of the Distal Femur in an Adolescent. ⁶²	Kaser R...Morales R	32354316	2020
40	Infrapatellar bursal injection with dextrose and saline are both effective treatments for Osgood-Schlatter disease. Letter to editor for: No superiority of dextrose injections over placebo injections for Osgood-Schlatter disease: a prospective randomized double‑blind study https://doi.org/10.1007/s00402-019-03297-2. ⁶²	Rabago D...Fullerton BD	31982926	2020
41	Activity Modification and Knee Strengthening for Osgood-Schlatter Disease: A Prospective Cohort Study. ⁶²	Rathleff MS...Thorborg K	32284945	2020
42	The Passive Mechanical Properties of Muscles and Tendons in Children Affected by Osgood-Schlatter Disease. ⁶²	Enomoto S...Kaga M	31343463	2020
43	Pain, Sports Participation, and Physical Function in Adolescents With Patellofemoral Pain and Osgood-Schlatter Disease: A Matched Cross-sectional Study. ⁶²	Rathleff MS...Thorborg K	31905093	2020
44	Increased Posterior Tibial Slope in Patients With Osgood-Schlatter Disease: A New Association. ⁶²	Green DW...Mintz DN	32004085	2020
45	Osgood-Schlatter Lesion Removed Arthroscopically in an Adult Patient. ⁶²	Tsakotos G...Tokis AV	32328374	2020
46	An Assessment of International Classification of Diseases, 10th Revision, Clinical Modification, Codes Used to Describe Common Pediatric Orthopedic Conditions. ⁶²	Rabenhorst BM...Blasier RD	31930410	2020
47	No superiority of dextrose injections over placebo injections for Osgood-Schlatter disease: a prospective randomized double-blind study. ⁶²	Nakase J...Tsuchiya H	31713082	2020
48	Osgood-Schlatter disease: a 2020 update of a common knee condition in children. ⁶²	Ladenhauf HN...Green DW	31714260	2020
49	Is There a Relationship between Patellofemoral Alignment and Osgood-Schlatter Disease? A Case-Control Study. ⁶²	Seyfettinoglu F...Acar B	30577051	2020
50	Mid inter-epicondyle trochlea intersection (MIELTI): Proposal of a new index for identifying the deepest part of the trochlea. ⁶²	Keehan R...Eldridge J	31703848	2019

Sources

Genes for Osgood-Schlatter's Disease

Genes related to Osgood-Schlatter's Disease (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	RPS13	Ribosomal Protein S13	Protein Coding	6.01	DISEASES inferred ¹⁴
2	SNORD13	Small Nucleolar RNA, C/D Box 13	RNA Gene	5.8	DISEASES inferred ¹⁴
3	ASTE1	Asteroid Homolog 1	Protein Coding	5.8	DISEASES inferred ¹⁴
4	MDGA1	MAM Domain Containing Glycosylphosphatidylinositol Anchor 1	Protein Coding	5.78	DISEASES inferred ¹⁴
5	VSX1	Visual System Homeobox 1	Protein Coding	5.59	DISEASES inferred ¹⁴
6	SKOR1	SKI Family Transcriptional Corepressor 1	Protein Coding	5.55	DISEASES inferred ¹⁴
7	BTBD9	BTB Domain Containing 9	Protein Coding	5.32	DISEASES inferred ¹⁴
8	PKP4	Plakophilin 4	Protein Coding	5.31	DISEASES inferred ¹⁴
9	APLF	Aprataxin And PNKP Like Factor	Protein Coding	5.31	DISEASES inferred ¹⁴
10	ESCO1	Establishment Of Sister Chromatid Cohesion N-Acetyltransferase 1	Protein Coding	5.28	DISEASES inferred ¹⁴

Sources

Variations for Osgood-Schlatter's Disease

Sources

Expression for Osgood-Schlatter's Disease

Search GEO for disease gene expression data for Osgood-Schlatter's Disease.

Sources

Pathways for Osgood-Schlatter's Disease

Sources

GO Terms for Osgood-Schlatter's Disease

Sources

Sources for Osgood-Schlatter's Disease

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: OSG001 MIFTS: 37	Osgood-Schlatter's Disease Categories: Bone diseases, Rare diseases	Data Licensing For inquiries, contact: [email protected]
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