MCID: OST006
MIFTS: 32

Osteoblastoma

Categories: Bone diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Osteoblastoma

Summaries for Osteoblastoma

MalaCards based summary : Osteoblastoma is related to osteoid osteoma and cervicitis. An important gene associated with Osteoblastoma is CTNNB1 (Catenin Beta 1). Affiliated tissues include bone, thyroid and pineal, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 76 Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the... more...

Related Diseases for Osteoblastoma

Graphical network of the top 20 diseases related to Osteoblastoma:



Diseases related to Osteoblastoma

Symptoms & Phenotypes for Osteoblastoma

GenomeRNAi Phenotypes related to Osteoblastoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-167 9.4 NELL1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.4 CTNNB1 NELL1 SPARC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-191 9.4 CTNNB1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-204 9.4 NELL1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.4 SPARC
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.4 NELL1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.4 SPARC
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.4 NELL1 SPARC
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-86 9.4 NELL1

Drugs & Therapeutics for Osteoblastoma

Search Clinical Trials , NIH Clinical Center for Osteoblastoma

Genetic Tests for Osteoblastoma

Anatomical Context for Osteoblastoma

MalaCards organs/tissues related to Osteoblastoma:

41
Bone, Thyroid, Pineal, Spinal Cord, Bone Marrow

Publications for Osteoblastoma

Articles related to Osteoblastoma:

(show top 50) (show all 569)
# Title Authors Year
1
A case of spinal osteoblastoma in the elderly: is it really a young patient's disease? ( 29421450 )
2018
2
A rare case of osteoblastoma from medieval Tuscany. ( 29304355 )
2018
3
Large Paediatric Central Osteoma with Osteoblastoma-Like Features in the Mandible. ( 29508129 )
2018
4
Aggressive osteoblastoma of the acetabulum: A diagnostic dilemma. ( 29928098 )
2018
5
Osteoblastoma of the mandible: A rare locally aggressive benign tumour. ( 29779915 )
2018
6
Neoadjuvant denosumab for the treatment of a sacral osteoblastoma. ( 29356985 )
2018
7
Osteoblastoma of the Hard Palate in a Child: A Rare Case. ( 29808179 )
2018
8
Recurrent rearrangements of FOS and FOSB define osteoblastoma. ( 29858576 )
2018
9
Periosteal osteoblastoma of the distal fibula with atypical radiological features: a case report. ( 29957764 )
2018
10
Giant periosteal aggressive epithelioid osteoblastoma: 21-year-old male presents case in the midshaft of his femur. ( 29525944 )
2018
11
Pseudomalignant osteoblastoma of the odontoid process. ( 29380146 )
2018
12
Eccentric, mature osseous cap: A distinct imaging feature of sinonasal osteoblastoma. ( 29644901 )
2018
13
Osteoblastoma of the elbow: analysis of 13 patients and literature review. ( 28634923 )
2017
14
Osteoblastoma Mimicking an Idiopathic Intracranial Hypertension Syndrome. ( 28553393 )
2017
15
Frontal skull osteoblastoma with aneurysmal bone cyst-like changes associated with trauma during pregnancy: a case report. ( 27853880 )
2017
16
Suboccipital osteoblastoma: Microsurgical resection of a rare entity. ( 28458947 )
2017
17
Aggressive Osteoblastoma in the Maxilla: Unusual Lesion in the Craniofacial Skeleton. ( 28468168 )
2017
18
Percutaneous radiofrequency ablation for spinal osteoid osteoma and osteoblastoma. ( 28391383 )
2017
19
Epithelioid osteoblastoma: A histopathological dilemma between juvenile ossifying fibroma and low-grade osteosarcoma. ( 28479709 )
2017
20
microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation. ( 28460435 )
2017
21
A rare case of osteoblastoma combined with severe scoliosis deformity, coronal and sagittal imbalance. ( 29258494 )
2017
22
Rare Aggressive Calvarial Osteoblastoma with Dural Invasion. ( 29204329 )
2017
23
Spinal osteoid osteoma progressed to osteoblastoma with paraspinal soft tissue mass: a unique presentation. ( 27999873 )
2017
24
Aggressive Osteoblastoma in the Maxilla: Unusual Lesion in the Craniofacial Skeleton. ( 28277479 )
2017
25
CT-guided radiofrequency ablation of spinal osteoblastoma: treatment and long-term follow-up. ( 28597707 )
2017
26
Elevated I^-hCG associated with aggressive Osteoblastoma. ( 28396962 )
2017
27
Osteoblastoma of the hamate bone - a case report. ( 28905333 )
2017
28
Breast osteoblastoma and recurrence after resection: Demonstration by color Doppler ultrasound. ( 28506022 )
2017
29
Preoperative Embolization and Complete Tumoral Resection of a Cervical Aggressive Epithelioid Osteoblastoma. ( 28710051 )
2017
30
Activation of the arachidonic acid metabolic pathway and induction of sleep disturbance by sacral osteoblastoma: A case report. ( 28781793 )
2017
31
Clinics in diagnostic imaging (174). L5 vertebral superior facet osteoblastoma (OB). ( 28210742 )
2017
32
Clinical management of a challenging malignancy, osteoblastoma-like osteosarcoma: a report of four cases and a review of the literature. ( 27574436 )
2016
33
Osteoblastoma of the thyroid cartilage. ( 27206395 )
2016
34
Agressive osteoblastoma in a seven-year-old girl's mandible: Treatment and six-year monitoring. ( 27518431 )
2016
35
The effect of simple local resection on pain and scoliotic curve in patients with scoliosis secondary to osteoid osteoma and osteoblastoma in the spine. ( 27130390 )
2016
36
Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report. ( 27981453 )
2016
37
Malignant transformation of a high-grade osteoblastoma of the petrous apex with subcutaneous metastasis. ( 27304442 )
2016
38
Osteoblastoma of the temporal articular tubercle misdiagnosed asA a temporomandibular joint disorder. ( 28043747 )
2016
39
Orbital Osteoblastoma: Technical Innovations in Resection and Reconstruction Using Virtual Surgery Simulation. ( 27516847 )
2016
40
Removal of osteoblastoma of the talar neck using standard anterior ankle Arthroscopyi19A case report. ( 27100951 )
2016
41
Osteoblastoma of the maxillary sinus in a child presenting with exophthalmos. ( 26895762 )
2016
42
Dorsal spine osteoblastoma. ( 27057242 )
2016
43
Osteoblastoma originating from frontoethmoidal sinus causing personality disorders and superior gaze palsy. ( 26755236 )
2016
44
Epithelioid osteoblastoma of maxilla: A rare and aggressive variant of a benign neoplasm at an uncommon site. ( 27601840 )
2016
45
Surgical management of an osteoblastoma involving the entire C2 vertebra and a review of literature. ( 26879919 )
2016
46
An Osteoblastoma of the Mandible: A Case Study. ( 29045089 )
2016
47
Anterior Reconstruction of C2-C3 Bodies in a 6-Year-Old Patient with a Huge Osteoblastoma: A Novel Technique. ( 26835212 )
2016
48
Non Aggressive Mandibular Osteoblastoma- A Rare Maxillofacial Entity. ( 27190965 )
2016
49
Osteoid osteoma of the temporal bone manifesting as first bite syndrome and a meta-analysis combined with osteoblastoma. ( 27106094 )
2016
50
Unusual presentation of osteoblastoma as vertebra plana - a case report and review of literature. ( 27664343 )
2016

Variations for Osteoblastoma

Expression for Osteoblastoma

Search GEO for disease gene expression data for Osteoblastoma.

Pathways for Osteoblastoma

GO Terms for Osteoblastoma

Biological processes related to Osteoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of osteoblast differentiation GO:0045669 9.26 CTNNB1 NELL1
2 cellular response to growth factor stimulus GO:0071363 9.16 CTNNB1 SPARC
3 limb development GO:0060173 8.96 CTNNB1 KREMEN1
4 Wnt signaling pathway GO:0016055 8.8 CTNNB1 KREMEN1 ZNRF3

Sources for Osteoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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