MCID: OST007
MIFTS: 30

Ostertagiasis

Categories: Infectious diseases

Aliases & Classifications for Ostertagiasis

MalaCards integrated aliases for Ostertagiasis:

Name: Ostertagiasis 12 44 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:3985
MeSH 44 D010029
UMLS 70 C0029471

Summaries for Ostertagiasis

Disease Ontology : 12 A trichostrongyloidiasis that involves parasitic infection of the ruminant gastrointestinal tract by nematodes of the genus Ostertagia.

MalaCards based summary : Ostertagiasis is related to fascioliasis and bronchitis. An important gene associated with Ostertagiasis is GAST (Gastrin), and among its related pathways/superpathways are C-type lectin receptor signaling pathway and Tuberculosis. Affiliated tissues include bone and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Ostertagiasis

Diseases related to Ostertagiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 158)
# Related Disease Score Top Affiliating Genes
1 fascioliasis 29.7 IL10 ALB
2 bronchitis 29.6 TLR4 IL10 ALB
3 trichostrongyloidiasis 10.3 MTERF3 GAST
4 granulomatous gastritis 10.3 GAST CR2
5 tropical sprue 10.2 GAST ALB
6 melon allergy 10.2 GAST ALB
7 gastritis, familial giant hypertrophic 10.2 GAST ALB
8 peptic esophagitis 10.2 GAST ALB
9 duodenitis 10.2 GAST ALB
10 bile reflux 10.2 GAST ALB
11 gastric fundus cancer 10.2 GAST ALB
12 functional gastric disease 10.2 GAST ALB
13 granulomatous hepatitis 10.2 CR2 ALB
14 vitamin metabolic disorder 10.1 GAST ALB
15 dermatomycosis 10.1 CR2 CLEC7A
16 tinea profunda 10.1 CLEC7A CLEC4E
17 tinea capitis 10.1 CLEC7A CLEC4E
18 phaeohyphomycosis 10.0 CLEC7A CLEC4E
19 chronic pyelonephritis 10.0 TLR4 ALB
20 tinea corporis 10.0 CLEC7A CLEC4E
21 blastomycosis 10.0 CLEC7A CLEC4E
22 pityriasis versicolor 10.0 CLEC7A CLEC4E
23 coccidioidomycosis 10.0 TLR4 CLEC7A
24 superficial mycosis 10.0 CLEC7A CLEC4E
25 chromoblastomycosis 10.0 CLEC7A CLEC4E
26 pyelitis 10.0 TLR4 ALB
27 dermatophytosis 10.0 CLEC7A CLEC4E
28 intestinal perforation 10.0 TLR4 ALB
29 hypersplenism 10.0 TLR4 ALB
30 mucormycosis 10.0 CLEC7A ALB
31 oral hairy leukoplakia 10.0 IL10 CR2
32 bacteriuria 10.0 TLR4 ALB
33 juvenile arthritis 10.0 IL10 CR2
34 autoimmune gastritis 10.0 IL10 GAST
35 nail disease 9.9 CLEC7A CLEC4E
36 enterocolitis 9.9 TLR4 IL10
37 oesophagostomiasis 9.9
38 metal allergy 9.9 TLR4 IL10
39 bacterial conjunctivitis 9.9 IL10 ALB
40 campylobacteriosis 9.9 TLR4 IL10
41 vaginal discharge 9.9 IL10 ALB
42 taeniasis 9.9 IL10 ALB
43 chlamydia pneumonia 9.9 TLR4 IL10
44 cardiomyopathy, familial hypertrophic, 20 9.9 IL10 ALB
45 babesiosis 9.9 IL10 ALB
46 iridocyclitis 9.9 TLR4 IL10
47 fungal meningitis 9.9 IL10 ALB
48 idiopathic neutropenia 9.9 TLR4 IL10
49 urethritis 9.9 TLR4 IL10
50 filarial elephantiasis 9.9 TLR4 IL10

Graphical network of the top 20 diseases related to Ostertagiasis:



Diseases related to Ostertagiasis

Symptoms & Phenotypes for Ostertagiasis

GenomeRNAi Phenotypes related to Ostertagiasis according to GeneCards Suite gene sharing:

26 (show all 30)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.83 IL10
2 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.83 CLEC7A
3 Increased shRNA abundance (Z-score > 2) GR00366-A-111 9.83 CLEC7A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-112 9.83 CLEC7A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.83 IL10
6 Increased shRNA abundance (Z-score > 2) GR00366-A-119 9.83 CLEC7A
7 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.83 CLEC7A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.83 IL10
9 Increased shRNA abundance (Z-score > 2) GR00366-A-128 9.83 TLR4
10 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.83 CLEC7A
11 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.83 CLEC7A
12 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.83 CLEC7A
13 Increased shRNA abundance (Z-score > 2) GR00366-A-152 9.83 IL10
14 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.83 CLEC7A
15 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.83 IL10
16 Increased shRNA abundance (Z-score > 2) GR00366-A-179 9.83 CLEC7A
17 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.83 CLEC7A
18 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.83 IL10
19 Increased shRNA abundance (Z-score > 2) GR00366-A-210 9.83 IL10
20 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.83 CLEC7A IL10
21 Increased shRNA abundance (Z-score > 2) GR00366-A-22 9.83 TLR4
22 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.83 CLEC7A
23 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.83 IL10
24 Increased shRNA abundance (Z-score > 2) GR00366-A-53 9.83 IL10
25 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.83 CLEC7A
26 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.83 IL10
27 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.83 IL10
28 Increased shRNA abundance (Z-score > 2) GR00366-A-68 9.83 IL10 TLR4
29 Increased shRNA abundance (Z-score > 2) GR00366-A-82 9.83 IL10
30 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.83 IL10

MGI Mouse Phenotypes related to Ostertagiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.76 ALB CLEC4E CLEC7A CR2 GAST IL10
2 digestive/alimentary MP:0005381 9.65 ALB CLEC7A GAST IL10 TLR4
3 immune system MP:0005387 9.56 ALB CLEC4E CLEC7A CR2 GAST IL10
4 mortality/aging MP:0010768 9.28 ALB CLEC4E CLEC7A CR2 GAST IL10

Drugs & Therapeutics for Ostertagiasis

Search Clinical Trials , NIH Clinical Center for Ostertagiasis

Cochrane evidence based reviews: ostertagiasis

Genetic Tests for Ostertagiasis

Anatomical Context for Ostertagiasis

MalaCards organs/tissues related to Ostertagiasis:

40
Bone, Liver

Publications for Ostertagiasis

Articles related to Ostertagiasis:

(show top 50) (show all 126)
# Title Authors PMID Year
1
An outbreak of Salmonella enterica serotype Choleraesuis in goitered gazelle (Gazella subgutrosa subgutrosa) and a Malayan tapir (Tapirus indicus). 61
22204065 2011
2
Severe ostertagiasis in a group of Scottish dairy heifers. 61
22167842 2011
3
Abomasal coccidiosis associated with proliferative abomasitis in a sheep. 61
17459846 2007
4
Type II ostertagiasis in llamas. 61
9429284 1997
5
[Ostertagiasis in bulls used for bullfights]. 61
8592911 1995
6
Ostertagiasis in suckler cows. 61
7886905 1994
7
Anthelmintics. 61
8484204 1993
8
The role of inhibited development in the epidemiology of Ostertagia infections. 61
8484216 1993
9
Current and future prospects for control of ostertagiasis in northern Europe--examples from Denmark. 61
8484221 1993
10
Ostertagiasis in the cow and weaned calf in the northeastern USA. 61
8484217 1993
11
The systematics of nematodes that cause ostertagiasis in domestic and wild ruminants in North America: an update and a key to species. 61
8484224 1993
12
Regulation of immunity to Ostertagia ostertagi. 61
8484225 1993
13
Evaluation of pepsinogen, gastrin and antibody response in diagnosing ostertagiasis. 61
8484209 1993
14
[The serological diagnosis of gastrointestinal nematode infections in cattle]. 61
8342328 1993
15
The epizootiology of gastrointestinal nematodes of cattle in selected areas of Oregon. 61
1413459 1992
16
Effect of ostertagiasis on copper status in sheep: a study involving use of copper oxide wire particles. 61
2267421 1990
17
Observations on parasitic gastroenteritis and parasitic bronchitis in calves over two grazing seasons. 61
2264245 1990
18
Anthelmintic resistance and the control of ovine ostertagiasis: a drug action model for genetic selection. 61
2777459 1989
19
Ostertagiasis in cattle. 61
2488343 1989
20
Visualization of eosinophil chemotactic factor in abomasal tissue of cattle by immunoperoxidase staining during Ostertagia ostertagi infection. 61
2658300 1989
21
Pathophysiological and parasitological studies on Ostertagia ostertagi infections in calves. 61
2704887 1989
22
Blood gastrin and pepsinogen responses to subclinical infection with Ostertagia ostertagi in adult dairy cattle. 61
3222546 1988
23
Effect of strategic anthelmintic treatment and pasture management on productivity and control of nematode parasites in weaner-yearling beef cattle. 61
3222550 1988
24
Feed intake of grazing calves exposed to trichostrongyle infection and treated with the morantel sustained release bolus. 61
3388730 1988
25
Ostertagiasis. Proceedings of a workshop. College Park, MD, 3-5 December 1986. 61
3363841 1988
26
Immunity to Ostertagia ostertagi. 61
3284164 1988
27
Control strategies for ostertagiasis. 61
3284160 1988
28
Systematics of the nematodes that cause ostertagiasis in cattle, sheep and goats in North America. 61
3284166 1988
29
Evaluation of abomasal enzyme and hormone levels in the diagnosis of ostertagiasis. 61
3284163 1988
30
Control of Ostertagia ostertagi infections in Australia. 61
3284168 1988
31
Epidemiology and control of bovine ostertagiasis in South America. 61
3284169 1988
32
Preliminary report: immunodiagnosis of pre-type II ostertagiasis. 61
3363842 1988
33
Aspects of the biology of Ostertagia ostertagi in relation to the genesis of ostertagiasis. 61
3284162 1988
34
Epidemiology of Ostertagia ostertagi in warm temperate regions of the United States. 61
3284165 1988
35
The epidemiology of bovine ostertagiasis in the north temperate regions of North America. 61
3284167 1988
36
Drug resistance in ostertagiasis. 61
3284171 1988
37
Sequential histopathologic changes of type I, pre-type II and type II ostertagiasis in cattle. 61
3363843 1988
38
Anthelmintics and control. 61
3284172 1988
39
Intracellular iron storage and the pathogenesis of paratuberculosis. Comparative studies with other mycobacterial, parasitic or infectious conditions of veterinary importance. 61
3346390 1988
40
A study on the effects of tactical drenchings with a benzimidazole against ostertagiasis in calves. 61
3202063 1988
41
Multiple forms of bovine pepsinogen: isolation and identification in serum from calves with ostertagiasis. 61
3444973 1987
42
Population biology of Ostertagia ostertagi and anthelmintic strategies against ostertagiasis in calves. 61
3696773 1987
43
A mathematical model of the population biology of Ostertagia ostertagi in calves and yearlings. 61
3696772 1987
44
Control of gastrointestinal parasitism in calves in Sweden over six years using the morantel sustained release bolus. 61
3629903 1987
45
The effects of late turnout on the epidemiology and control of ostertagiasis in calves. 61
3590609 1987
46
Ostertagiasis in young lambs in spring. 61
3787996 1986
47
The sequential development of type I and type II ostertagiasis in young cattle with special reference to biochemical and serological changes. 61
3750807 1986
48
Anthelmintics for cattle. 61
3488116 1986
49
Response to transplanted adult Ostertagia ostertagi in calves. 61
3738234 1986
50
The development and mortality of the non-infective free-living stages of Ostertagia ostertagi in the field and in laboratory culture. 61
3714308 1986

Variations for Ostertagiasis

Expression for Ostertagiasis

Search GEO for disease gene expression data for Ostertagiasis.

Pathways for Ostertagiasis

Pathways related to Ostertagiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.57 IL10 CLEC7A CLEC4E
2 11.18 TLR4 IL10 CLEC7A CLEC4E
3 10.95 TLR4 IL10 CR2
4 10.8 TLR4 IL10

GO Terms for Ostertagiasis

Biological processes related to Ostertagiasis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.81 TLR4 CR2 CLEC7A CLEC4E
2 innate immune response GO:0045087 9.71 TLR4 CR2 CLEC7A CLEC4E
3 positive regulation of nitric oxide biosynthetic process GO:0045429 9.52 TLR4 CLEC7A
4 negative regulation of interferon-gamma production GO:0032689 9.49 TLR4 IL10
5 positive regulation of interleukin-12 production GO:0032735 9.48 TLR4 CLEC7A
6 positive regulation of interleukin-10 production GO:0032733 9.46 TLR4 CLEC7A
7 B cell proliferation GO:0042100 9.43 IL10 CR2
8 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.37 TLR4 CLEC7A
9 defense response to protozoan GO:0042832 9.32 IL10 CLEC7A
10 positive regulation of stress-activated MAPK cascade GO:0032874 9.26 TLR4 CLEC7A
11 positive regulation of macrophage activation GO:0043032 9.16 TLR4 IL10
12 positive regulation of MHC class II biosynthetic process GO:0045348 8.96 TLR4 IL10
13 detection of fungus GO:0016046 8.62 TLR4 CLEC7A

Molecular functions related to Ostertagiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pattern recognition receptor activity GO:0038187 8.62 CLEC7A CLEC4E

Sources for Ostertagiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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