Aliases & Classifications for Otomycosis

MalaCards integrated aliases for Otomycosis:

Name: Otomycosis 12 45 15 74
Singapore Ear 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050147
MeSH 45 D059249
UMLS 74 C0029895

Summaries for Otomycosis

Disease Ontology : 12 An otitis externa which is a disease of the ear produced by the growth of fungi in the external auditory canal. It is characterized by inflammation, pruritus, scaling and severe discomfort. The most common fungi are Aspergillus niger and Candida albicans.

MalaCards based summary : Otomycosis, also known as singapore ear, is related to chronic fungal otitis externa and multiple sclerosis, and has symptoms including earache An important gene associated with Otomycosis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). The drugs Clotrimazole and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include testes.

Wikipedia : 77 Otomycosis is a fungal ear infection, a superficial mycotic infection of the outer ear canal. It is... more...

Related Diseases for Otomycosis

Diseases related to Otomycosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 chronic fungal otitis externa 11.2
2 multiple sclerosis 10.0
3 schizophrenia 10.0
4 tetralogy of fallot 10.0
5 coccidioidomycosis 10.0
6 dermatomycosis 10.0
7 middle ear disease 10.0
8 otitis externa 10.0

Graphical network of the top 20 diseases related to Otomycosis:



Diseases related to Otomycosis

Symptoms & Phenotypes for Otomycosis

UMLS symptoms related to Otomycosis:


earache

Drugs & Therapeutics for Otomycosis

Drugs for Otomycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clotrimazole Approved, Vet_approved Phase 3,Not Applicable 23593-75-1 2812
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
3
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
4 Pharmaceutical Solutions Phase 3,Not Applicable
5 Hormone Antagonists Phase 3,Phase 2
6 Hormones Phase 3,Phase 2
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
8 Peripheral Nervous System Agents Phase 3
9 Anti-Inflammatory Agents Phase 3
10 BB 1101 Phase 3
11 HIV Protease Inhibitors Phase 3
12 Antineoplastic Agents, Hormonal Phase 3
13
protease inhibitors Phase 3
14 Antiemetics Phase 3
15 Gastrointestinal Agents Phase 3
16 glucocorticoids Phase 3
17 Autonomic Agents Phase 3
18
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
19 Anti-Infective Agents Phase 2,Not Applicable
20 Steroid Synthesis Inhibitors Phase 2
21 Cytochrome P-450 CYP2C9 Inhibitors Phase 2
22 Cytochrome P-450 Enzyme Inhibitors Phase 2
23 Cytochrome P-450 CYP3A Inhibitors Phase 2
24 Antifungal Agents Phase 2
25
Ethanol Approved Not Applicable 64-17-5 702
26
carbamide peroxide Approved Not Applicable 124-43-6
27 Anti-Infective Agents, Local Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Study to Assess the Efficacy and Safety of G238 Compared to Clotrimazole Otic Solution in the Treatment of Otomycosis Completed NCT01993823 Phase 3 G238;Clotrimazole
2 SVT-15652 Otic Solution for the Treatment of Otomycosis Not yet recruiting NCT03686384 Phase 3 SVT-15652;Placebo
3 SVT-15652 Otic Solution for the Treatment of Otomycosis. Not yet recruiting NCT03686397 Phase 3 SVT-15652;Placebo
4 FST-201 In The Treatment of Acute Fungal Otitis Externa Terminated NCT00945646 Phase 3 FST-201 (dexamethasone 0.1%) Otic Suspension;Vehicle
5 Dose-Ranging Study for Miconazole Oil for Treatment of Otomycosis Recruiting NCT03130738 Phase 2 7-Day Miconazole Oil (Miconazole 2%);14-Day Miconazole Oil (Miconazole 2%);14-Day Placebo - Oil Vehicle
6 Effectiveness of 3% Boric Acid in 70% Alcohol Versus 1% Clotrimazole Solution in Otomycosis Patients Completed NCT01547221 Not Applicable clotrimazole;3% Boric acid

Search NIH Clinical Center for Otomycosis

Cochrane evidence based reviews: otomycosis

Genetic Tests for Otomycosis

Anatomical Context for Otomycosis

MalaCards organs/tissues related to Otomycosis:

42
Testes

Publications for Otomycosis

Articles related to Otomycosis:

(show top 50) (show all 154)
# Title Authors Year
1
The Molecular Identification and Antifungal Susceptibilities of Aspergillus Species Causing Otomycosis in Tochigi, Japan. ( 30291485 )
2019
2
Single Dose Topical Application of Clotrimazole for the Treatment of Otomycosis: Is This Enough? ( 30518195 )
2019
3
Bayesian analysis of two methods MALDI-TOF-MS system and culture test in otomycosis infection. ( 30775695 )
2019
4
Clinical and microbial epidemiology of otomycosis in the city of Yasuj, southwest Iran, revealing Aspergillus tubingensis as the dominant causative agent. ( 30801244 )
2019
5
Efficacy of topical clotrimazole vs. topical tolnaftate in the treatment of otomycosis. A randomized controlled clinical trial. ( 30826311 )
2019
6
Molecular epidemiology of otomycosis in Isfahan revealed a large diversity in causative agents. ( 31063125 )
2019
7
Povidone iodine soaked gelfoam for the treatment of recalcitrant otomycosis - Our experiences at a tertiary care teaching hospital of eastern India. ( 29223643 )
2018
8
Assessment of Response to Treatment in Patients with Otomycosis. ( 29387663 )
2018
9
Species identification and in vitro antifungal susceptibility testing of Aspergillus section Nigri strains isolated from otomycosis patients. ( 29540288 )
2018
10
Efficacy and safety of eberconazole 1% otic solution compared to clotrimazole 1% solution in patients with otomycosis. ( 29551350 )
2018
11
Successful treatment of a recurrent Aspergillus niger otomycosis with local application of voriconazole. ( 29673769 )
2018
12
Self-injury in schizophrenia as predisposing factor for otomycosis. ( 30069425 )
2018
13
Effect of combination therapy with ceftizoxime and clotrimazole in the treatment of otomycosis. ( 30186989 )
2018
14
Identification of Fungal Pathogens in Otomycosis and Their Drug Sensitivity: Our Experience. ( 30357045 )
2018
15
Candida auris otomycosis in Iran and review of recent literature. ( 30585653 )
2018
16
Otomycosis in immunocompetent patients: Clinical and mycological features. Our experience with 40 cases. ( 28834405 )
2018
17
Comparison of the recovery rate of otomycosis using betadine and clotrimazole topical treatment. ( 28549873 )
2018
18
Otomycosis in Damascus, Syria: Etiology and clinical features. ( 29707671 )
2017
19
Otomycosis in a Rural Community Attending a Tertiary Care Hospital: Assessment of Risk Factors and Identification of Fungal and Bacterial Agents. ( 28764159 )
2017
20
A case of bilateral otomycosis associated with Aspergillus flavus and A. terreus in Taiwan. ( 28501466 )
2017
21
Antifungal Effect of Malaysian Aloe vera Leaf Extract on Selected Fungal Species of Pathogenic Otomycosis Species in In Vitro Culture Medium. ( 28042402 )
2017
22
Effectiveness of 3 per cent boric acid in 70 per cent alcohol versus 1 per cent clotrimazole solution in otomycosis patients: a randomised, controlled trial. ( 27477534 )
2016
23
Large discrepancies in otomycosis treatment in private ear, nose, and throat clinics in Denmark. ( 27127015 )
2016
24
A comparison of Locacorten-Vioform and clotrimazole in otomycosis: A systematic review and one-way meta-analysis. ( 26600419 )
2016
25
Lamisil, a potent alternative antifungal drug for otomycosis. ( 28680976 )
2015
26
Etiologic Agents of Otomycosis in the North-Western Area of Iran. ( 26495108 )
2015
27
Epidemiology, causative agents, and risk factors affecting human otomycosis infections. ( 26422852 )
2015
28
Scedosporium apiospermum causing otomycosis in an immunocompetent child with tympanostomy tubes: Management of this rare entity. ( 26298623 )
2015
29
Otomycosis in Adolescent Patients Referred to the Therapeutic Centers in Babol City, Iran. ( 26060563 )
2015
30
Otomycosis in iran: a review. ( 25633436 )
2015
31
Type of Antifungals: Does it Matter in Empirical Treatment of Otomycosis? ( 25621236 )
2015
32
Otomycosis in the north of Iran: common pathogens and resistance to antifungal agents. ( 23595615 )
2014
33
Treatment of refractory Aspergillus otomycosis with voriconazole: case series and review. ( 24909800 )
2014
34
Otomycosis; clinical features, predisposing factors and treatment implications. ( 24948980 )
2014
35
Primary otomycosis in the Indian subcontinent: predisposing factors, microbiology, and classification. ( 24949016 )
2014
36
Otomycosis in Jos: Predisposing factors and Management. ( 26690089 )
2014
37
Prevalence of otomycosis in Khouzestan Province, south-west Iran. ( 23164073 )
2013
38
Effectiveness of 7.5 percent povidone iodine in comparison to 1 percent clotrimazole with lignocaine in the treatment of otomycosis. ( 23984100 )
2013
39
Efficacy of topical clotrimazole in treatment of otomycosis. ( 25098061 )
2013
40
Species assignment and antifungal susceptibilities of black aspergilli recovered from otomycosis cases in Iran. ( 21895787 )
2012
41
Otomycosis in Shanghai: aetiology, clinical features and therapy. ( 21999222 )
2012
42
Molecular identification and antifungal susceptibilities of black Aspergillus isolates from otomycosis cases in Hungary. ( 22359155 )
2012
43
Otomycosis in immunocompetent and immunocompromised patients: comparative study and literature review. ( 22430336 )
2012
44
Otomycosis with Perforated Tympanic Membrane: Self medication with Topical Antifungal Solution versus Medicated Ear Wick. ( 23267306 )
2012
45
Antibiotic resistance and otomycosis in the draining ear: culture results by diagnosis. ( 21041003 )
2011
46
Otomycosis due to filamentous fungi. ( 21499908 )
2011
47
A clinical study on the effect of Arka Taila in the management of Karnasrava (Otomycosis). ( 22529649 )
2011
48
Otomycosis in central iran: a clinical and mycological study. ( 22737432 )
2011
49
Otomycosis: Diagnosis and treatment. ( 20347664 )
2010
50
Chronic monolateral otomycosis in a dog caused by Aspergillus ochraceus. ( 20409075 )
2010

Variations for Otomycosis

Expression for Otomycosis

Search GEO for disease gene expression data for Otomycosis.

Pathways for Otomycosis

GO Terms for Otomycosis

Sources for Otomycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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