MCID: OVR003
MIFTS: 26

Ovarian Angiosarcoma

Categories: Cancer diseases, Cardiovascular diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Angiosarcoma

MalaCards integrated aliases for Ovarian Angiosarcoma:

Name: Ovarian Angiosarcoma 12 15 73
Hemangiosarcoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4527
NCIt 50 C5232
UMLS 73 C1335152

Summaries for Ovarian Angiosarcoma

Disease Ontology : 12 An ovary sarcoma that is a malignant vascular tumor that derives from blood vessels.

MalaCards based summary : Ovarian Angiosarcoma, also known as hemangiosarcoma of ovary, is related to angiosarcoma and skin epithelioid hemangioma. An important gene associated with Ovarian Angiosarcoma is HBA1 (Hemoglobin Subunit Alpha 1), and among its related pathways/superpathways is C-MYB transcription factor network. Affiliated tissues include ovary, skin and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Ovarian Angiosarcoma

Diseases related to Ovarian Angiosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 angiosarcoma 10.4
2 skin epithelioid hemangioma 10.0 CD34 HBA1
3 intravascular fasciitis 10.0 CD34 HBA1
4 pediatric angiosarcoma 10.0 CD34 HBA1
5 thyroid angiosarcoma 10.0 CD34 HBA1
6 spleen angiosarcoma 10.0 CD34 HBA1
7 bone epithelioid hemangioma 10.0 CD34 HBA1
8 thyroid sarcoma 10.0 CD34 HBA1
9 hobnail hemangioma 10.0 CD34 HBA1
10 hordeolum 10.0 CD34 HBA1
11 glomeruloid hemangioma 10.0 CD34 HBA1
12 hemangioma of liver 10.0 CD34 HBA1
13 spleen cancer 10.0 CD34 HBA1
14 conventional angiosarcoma 10.0 CD34 HBA1
15 mixed liposarcoma 10.0 CD34 HBA1
16 erythema elevatum diutinum 10.0 CD34 HBA1
17 breast angiosarcoma 10.0 CD34 HBA1
18 senile angioma 10.0 CD34 HBA1
19 interstitial emphysema 10.0 CD34 HBA1
20 angiomyoma 10.0 CD34 HBA1
21 chorioangioma 10.0 CD34 HBA1
22 spindle cell liposarcoma 10.0 CD34 HBA1
23 alveoli adenoma 10.0 CD34 HBA1
24 mesenchymal cell neoplasm 10.0 CD34 HBA1
25 infiltrating lipoma 10.0 CD34 HBA1
26 hemangioma of intra-abdominal structure 10.0 CD34 HBA1
27 liver angiosarcoma 10.0 CD34 HBA1
28 congenital epulis 10.0 CD34 HBA1
29 nephrogenic adenofibroma 10.0 CD34 HBA1
30 vascular cancer 10.0 CD34 HBA1
31 skin benign neoplasm 10.0 CD34 HBA1
32 connective tissue cancer 10.0 CD34 HBA1
33 malignant epithelioid hemangioendothelioma 9.9 CD34 MYC
34 malignant hemangioma 9.9 CD34 MYC
35 peripheral nervous system neoplasm 9.9 CD34 MYC
36 leukocyte disease 9.9 CD34 MYC
37 nervous system cancer 9.9 CD34 MYC
38 acquired immunodeficiency syndrome 9.9 CD34 MYC
39 precursor t-cell acute lymphoblastic leukemia 9.9 CD34 MYC
40 gastrointestinal system cancer 9.9 CD34 MYC
41 myeloma, multiple 9.8 CD34 MYC
42 diffuse alveolar hemorrhage 9.8
43 leukemia, chronic myeloid 9.8 CD34 MYC
44 hematologic cancer 9.8 CD34 MYC
45 lymphoma, non-hodgkin, familial 9.8 CD34 MYC
46 acute promyelocytic leukemia 9.8 CD34 MYC
47 ovary sarcoma 9.7 CD34 HBA1 MYC
48 venous hemangioma 9.7 CD34 HBA1 MYC
49 lymphangiosarcoma 9.7 CD34 HBA1 MYC
50 large intestine cancer 9.7 CD34 HBA1 MYC

Graphical network of the top 20 diseases related to Ovarian Angiosarcoma:



Diseases related to Ovarian Angiosarcoma

Symptoms & Phenotypes for Ovarian Angiosarcoma

GenomeRNAi Phenotypes related to Ovarian Angiosarcoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.17 CD34
2 Increased shRNA abundance (Z-score > 2) GR00366-A-178 9.17 MYC
3 Increased shRNA abundance (Z-score > 2) GR00366-A-24 9.17 CD34 MYC
4 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.17 MYC
5 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.17 CD34
6 Increased shRNA abundance (Z-score > 2) GR00366-A-73 9.17 MYC

Drugs & Therapeutics for Ovarian Angiosarcoma

Search Clinical Trials , NIH Clinical Center for Ovarian Angiosarcoma

Genetic Tests for Ovarian Angiosarcoma

Anatomical Context for Ovarian Angiosarcoma

MalaCards organs/tissues related to Ovarian Angiosarcoma:

41
Ovary, Skin, Liver, Bone, Spleen, Thyroid, Myeloid

Publications for Ovarian Angiosarcoma

Articles related to Ovarian Angiosarcoma:

(show all 13)
# Title Authors Year
1
Bilateral ovarian angiosarcoma arising from the mature cystic teratomas - A case report and review of the literature. ( 29227858 )
2018
2
Pediatric Primary Ovarian Angiosarcoma: From Rarity to a Realization. ( 30179666 )
2018
3
Primary ovarian angiosarcoma in a 12- year -old girl: a case report of an exceptional localization in a context of limited resources country. ( 28852325 )
2017
4
Ovarian angiosarcoma: a case report and review of the literature. ( 24520828 )
2014
5
Gemcitabine-based regimen for primary ovarian angiosarcoma with MYC amplification. ( 25489268 )
2014
6
Complete response after MAID treatment for advanced primary ovarian angiosarcoma: case report and literature review. ( 24984551 )
2014
7
A metastatic ovarian angiosarcoma mimicking hematologic neoplasia at diagnosis. ( 24847252 )
2014
8
Ovarian angiosarcoma: Extended survival following optimal cytoreductive surgery and adjuvant chemotherapy. ( 24371666 )
2012
9
Primary ovarian angiosarcoma--review of the literature and report of a case with coexisting chylothorax. ( 17713094 )
2007
10
Primary ovarian angiosarcoma presenting as malignant cells in ascites: case report and review of the literature. ( 15830366 )
2005
11
Primary ovarian angiosarcoma: a case report and literature review. ( 9952341 )
1998
12
Diffuse alveolar hemorrhage caused by lung metastasis of ovarian angiosarcoma. ( 8894742 )
1996
13
Treatment of primary ovarian angiosarcoma with ifosfamide and doxorubicin. ( 8188092 )
1994

Variations for Ovarian Angiosarcoma

Expression for Ovarian Angiosarcoma

Search GEO for disease gene expression data for Ovarian Angiosarcoma.

Pathways for Ovarian Angiosarcoma

Pathways related to Ovarian Angiosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.52 CD34 MYC

GO Terms for Ovarian Angiosarcoma

Biological processes related to Ovarian Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell proliferation GO:0008283 9.16 CD34 MYC
2 negative regulation of gene expression GO:0010629 8.96 CD34 MYC
3 oxygen transport GO:0015671 8.62 HBA1 MYC

Molecular functions related to Ovarian Angiosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription factor binding GO:0008134 8.62 CD34 MYC

Sources for Ovarian Angiosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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