MCID: OVR041
MIFTS: 32

Ovarian Benign Neoplasm

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Benign Neoplasm

MalaCards integrated aliases for Ovarian Benign Neoplasm:

Name: Ovarian Benign Neoplasm 12 15
Benign Ovarian Neoplasm 17

Classifications:



External Ids:

Disease Ontology 12 DOID:0060112

Summaries for Ovarian Benign Neoplasm

Disease Ontology : 12 A female reproductive organ benign neoplasm that is located in the ovary.

MalaCards based summary : Ovarian Benign Neoplasm, also known as benign ovarian neoplasm, is related to luteoma and ovarian cystadenoma. An important gene associated with Ovarian Benign Neoplasm is EPPIN (Epididymal Peptidase Inhibitor), and among its related pathways/superpathways are Cytoskeletal Signaling and Glucocorticoid receptor regulatory network. Affiliated tissues include ovary, thyroid and liver, and related phenotypes are Decreased HPV16-GFP infection and endocrine/exocrine gland

Related Diseases for Ovarian Benign Neoplasm

Diseases related to Ovarian Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 479)
# Related Disease Score Top Affiliating Genes
1 luteoma 32.0 FSHR EPPIN CALB2
2 ovarian cystadenoma 32.0 KRT7 CEACAM5 BRCA1
3 ovarian brenner tumor 32.0 WT1 KRT7 KRT20
4 ovarian gonadoblastoma 31.6 WT1 PRL CALB2 AFP
5 benign struma ovarii 31.0 WT1 TG PAX8 HRAS AMH
6 ovarian serous adenofibroma 30.9 TP53 TG KRT7 CALB2 BRCA1 AMH
7 cystadenofibroma 30.8 WT1 TP53 PAX8 MUC1 KRT7 CALB2
8 cystadenoma 29.2 MUC1 KRT7 KRT20 CEACAM5 CALB2 BRCA1
9 ovarian endometrioid adenofibroma 11.1
10 ovarian clear cell adenofibroma 11.1
11 mixed epithelial tumor of ovary 11.1
12 ovarian mucinous adenofibroma 11.1
13 ovarian fibrothecoma 10.4 DES CALB2
14 rete testis adenoma 10.4 PAX8 CALB2
15 bartholin's gland disease 10.4 KRT7 CALB2
16 gestational ovarian choriocarcinoma 10.4 CEACAM5 AFP
17 benign metastasizing leiomyoma 10.4 KRT7 DES
18 adult type testicular granulosa cell tumor 10.4 CALB2 AFP
19 leukoplakia of penis 10.4 KRT7 CEACAM5
20 wolffian duct adenoma 10.4 PAX8 KRT7
21 malignant epithelial mesothelioma 10.4 CEACAM5 CALB2
22 bartholin's gland carcinoma 10.4 PAX8 KRT7
23 rectum neuroendocrine neoplasm 10.4 KRT7 AFP
24 atrophic vulva 10.4 KRT7 KRT20
25 liver lipoma 10.4 CEACAM5 AFP
26 ureter adenocarcinoma 10.4 KRT7 CEACAM5
27 mucinous adenofibroma 10.4 KRT7 CEACAM5
28 cervical clear cell adenocarcinoma 10.4 PAX8 AFP
29 spermatocele 10.4 CALB2 AFP
30 ovarian primitive germ cell tumor 10.4 KRT7 AFP
31 ovarian endodermal sinus tumor 10.4 KRT7 AFP
32 malignant acrospiroma 10.4 KRT7 CEACAM5
33 anal paget's disease 10.4 KRT7 CEACAM5
34 infected hydrocele 10.4 CALB2 AFP
35 urachal adenocarcinoma 10.4 CEACAM5 AFP
36 cystitis cystica 10.4 KRT7 KRT20
37 cutaneous mucoepidermoid carcinoma 10.4 KRT7 CEACAM5
38 external ear carcinoma 10.4 KRT7 CEACAM5
39 thymus lipoma 10.4 KRT20 AFP
40 immune system organ benign neoplasm 10.4 KRT20 AFP
41 vulval paget's disease 10.4 KRT7 CEACAM5
42 liver inflammatory pseudotumor 10.4 CEACAM5 AFP
43 urinary bladder small cell neuroendocrine carcinoma 10.4 KRT7 KRT20
44 rectum signet ring adenocarcinoma 10.4 CEACAM5 AFP
45 eyelid carcinoma 10.4 KRT7 KRT20
46 urethral diverticulum 10.3 PAX8 KRT7
47 jejunal neoplasm 10.3 KRT7 KRT20
48 eccrine adenocarcinoma 10.3 KRT7 CEACAM5
49 jejunal cancer 10.3 KRT7 KRT20
50 thymus adenocarcinoma 10.3 KRT20 CEACAM5

Graphical network of the top 20 diseases related to Ovarian Benign Neoplasm:



Diseases related to Ovarian Benign Neoplasm

Symptoms & Phenotypes for Ovarian Benign Neoplasm

GenomeRNAi Phenotypes related to Ovarian Benign Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased HPV16-GFP infection GR00350-A 8.8 AFP DES HRAS

MGI Mouse Phenotypes related to Ovarian Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.96 AFP AMH BRCA1 FSHR HRAS PAX8
2 homeostasis/metabolism MP:0005376 9.93 AFP AMH BRCA1 DES FSHR HRAS
3 neoplasm MP:0002006 9.56 AFP AMH BRCA1 FSHR HRAS PRL
4 reproductive system MP:0005389 9.28 AFP AMH BRCA1 FSHR PAX8 PRL

Drugs & Therapeutics for Ovarian Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Ovarian Benign Neoplasm

Genetic Tests for Ovarian Benign Neoplasm

Anatomical Context for Ovarian Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Ovarian Benign Neoplasm:

19
Ovary

MalaCards organs/tissues related to Ovarian Benign Neoplasm:

40
Ovary, Thyroid, Liver, Lung, Breast, Colon, Thymus

Publications for Ovarian Benign Neoplasm

Articles related to Ovarian Benign Neoplasm:

(show all 32)
# Title Authors PMID Year
1
Müllerian Mucinous Cystadenomas of the Ovary: A Report of 25 Cases of an Unheralded Benign Ovarian Neoplasm Often Associated With Endometriosis and a Brief Consideration of Neoplasms Arising From the Latter. 61
33577227 2021
2
Collision Glial Neoplasms Arising in an Ovarian Mature Cystic Teratoma: A Rare Event. 61
32082676 2020
3
Evaluation of adnexal tumours in the International Ovarian Tumor Analysis system in reference to histopathological results. 61
31975980 2019
4
Signet Ring Stromal Cell Tumor: A Legitimate (Benign) Mimic of Krukenberg Tumor. 61
30281366 2018
5
Variability in surgical management of benign ovarian neoplasms in children. 61
28343661 2017
6
Oligodendroglial cell proliferation arising in an ovarian mature cystic teratoma. Clinicopathological, inmunohistochemical, and ultrastructural study of a case that may represent an oligodendroglioma. 61
28029275 2017
7
Oncogenic Activation of the Wnt/β-Catenin Signaling Pathway in Signet Ring Stromal Cell Tumor of the Ovary. 61
26509912 2016
8
Clinical relevance of expression of B7-H1 and B7-H4 in ovarian cancer. 61
27073557 2016
9
A rare benign ovarian tumour. 61
26933186 2016
10
[A woman with floating spheres in her abdomen]. 61
25740190 2015
11
Clinico-histopathological analysis of neoplastic and non-neoplastic lesions of the ovary: a 3-year prospective study in dhule, north maharashtra, India. 61
25302198 2014
12
Unexpected ovarian malignancy found after laparoscopic surgery in patients with adnexal masses--a single institutional experience. 61
25129994 2014
13
Huge Benign Ovarian Cystic Teratoma in a Patient with a History of Hansen's Disease. 61
25210635 2014
14
Coexistence of benign ovarian serous cystadenoma and tuberculosis in a young woman. 61
24005462 2013
15
Histopathological pattern of ovarian neoplasms and their age distribution in the western region of Saudi Arabia. 61
22273650 2012
16
[Diagnostic value of combining detection of human epididymis protein 4 and CA125 in patients with malignant ovarian carcinoma]. 61
22093635 2011
17
[The system of rehabilitation of specific functions of the female body of patients with benign ovarian neoplasm after urgent operations]. 61
21899077 2011
18
A retrospective study of ovarian tumours and tumour-like lesions. 61
21409917 2010
19
Bilateral sclerosing stromal tumor of the ovary in a premenarchal girl. 61
19283376 2009
20
[Sclerosing stromal tumor--a rare benign ovarian neoplasm]. 61
18646673 2008
21
[Evaluation of selected serum protein markers as early detectors of ovarian cancer]. 61
18592865 2008
22
Cytologic differentiation of struma ovarii from other ovarian neoplasms. 61
18323278 2008
23
Unaware of a giant serous cyst adenoma: a case report. 61
16249904 2006
24
[Sclerosing stromal ovarial tumor--a case report and review]. 61
16028379 2005
25
Sulfatides in ovarian tumors: clinicopathological correlates. 61
14764034 2004
26
Sclerosing stromal tumor of the ovary in a premenarchal female. 61
12497242 2003
27
Sclerosing stromal tumour--a rare ovarian benign neoplasm: description of three cases. 61
11820573 2001
28
[True and pseudo-Meigs' syndrome]. 61
10337073 1998
29
Ovarian and uterine disease in women with colorectal cancer. 61
8990444 1997
30
Primary lymphatic dissemination of malignant elements in a mature cystic ovarian teratoma. 61
7729744 1995
31
The prevalence of plasma heparin neutralizing activity and the effect of treatment on it in women with a gynecologic malignancy. 61
3260749 1988
32
Cholesterol granulomas in lymph nodes draining a benign ovarian neoplasm. 61
3840989 1985

Variations for Ovarian Benign Neoplasm

Expression for Ovarian Benign Neoplasm

Search GEO for disease gene expression data for Ovarian Benign Neoplasm.

Pathways for Ovarian Benign Neoplasm

Pathways related to Ovarian Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.95 MUC1 KRT7 KRT20 DES
2 11.05 TP53 PRL AFP
3 10.62 TP53 HRAS BRCA1

GO Terms for Ovarian Benign Neoplasm

Biological processes related to Ovarian Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.85 WT1 TP53 HRAS BRCA1 AMH
2 cellular response to gonadotropin stimulus GO:0071371 9.43 WT1 PAX8
3 sex determination GO:0007530 9.4 WT1 AMH
4 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.37 TP53 MUC1
5 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.33 WT1 TP53 PRL
6 metanephric S-shaped body morphogenesis GO:0072284 9.32 WT1 PAX8
7 metanephric epithelium development GO:0072207 9.26 WT1 PAX8
8 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.13 TP53 MUC1 BRCA1
9 gonad development GO:0008406 8.8 WT1 FSHR AMH

Molecular functions related to Ovarian Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription regulatory region sequence-specific DNA binding GO:0000976 8.92 WT1 TP53 PAX8 BRCA1

Sources for Ovarian Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....