Ovarian Cyst disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: OVR046 MIFTS: 50	Ovarian Cyst Categories: Endocrine diseases, Reproductive diseases, Cancer diseases
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Aliases & Classifications for Ovarian Cyst

MalaCards integrated aliases for Ovarian Cyst:

Name: Ovarian Cyst ¹² ²⁹ ⁶ ¹⁵

Ovarian Cysts ⁵⁵ ⁴³ ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases Reproductive diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the genitourinary system

Noninflammatory disorders of female genital tract

Noninflammatory disorders of ovary, fallopian tube and broad ligament

Other and unspecified ovarian cysts

External Ids:

Disease Ontology ¹² DOID:5119

ICD10 ³³ N83.2

ICD9CM ³⁵ 620.2

SNOMED-CT ⁶⁸ 198586000

UMLS ⁷³ C0029513 C0029927

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Summaries for Ovarian Cyst

MedlinePlus : ⁴³ The ovaries are part of the female reproductive system. They produce a woman's eggs and make female hormones. Ovarian cysts are fluid-filled sacs in or on an ovary. They usually form during ovulation, when the ovary releases an egg. They are usually harmless and go away by themselves. Most women have them sometime during their lives. Most ovarian cysts are small and don't cause symptoms. Women may not find out that they have them until they have a pelvic exam. If there are symptoms, they may include Pressure Bloating Swelling Pain in the lower abdomen, on the side where the cyst is If your health care provider finds a cyst, you may be able to wait to see if it gets bigger. You may need surgery if you have pain, are past menopause, or if the cyst does not go away. If a cyst bursts or causes bleeding, you should get medical help right away. Birth control pills can help prevent new cysts. Rarely, ovarian cysts can become cancerous. This risk increases as you get older. A health problem that involves ovarian cysts is polycystic ovary syndrome (PCOS). Women with PCOS can have high levels of male hormones, irregular or no periods, and small ovarian cysts. Dept. of Health and Human Services Office on Women's Health

MalaCards based summary : Ovarian Cyst, also known as ovarian cysts, is related to corpus luteum cyst and ovarian disease, and has symptoms including pelvic pain An important gene associated with Ovarian Cyst is MUC16 (Mucin 16, Cell Surface Associated), and among its related pathways/superpathways are Fluid shear stress and atherosclerosis and Endochondral Ossification. The drugs Zinc and Orlistat have been mentioned in the context of this disorder. Affiliated tissues include ovary, liver and bone, and related phenotypes are endocrine/exocrine gland and reproductive system

Wikipedia : ⁷⁶ An ovarian cyst is a fluid-filled sac within the ovary. Often they cause no symptoms. Occasionally they... more...

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Related Diseases for Ovarian Cyst

Diseases in the Ovarian Cyst family:

Malignant Ovarian Cyst

Diseases related to Ovarian Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)

#	Related Disease	Score	Top Affiliating Genes
1	corpus luteum cyst	31.7	AFP FOXL2 MUC16
2	ovarian disease	31.7	FOXL2 NOBOX PRL
3	cystadenocarcinoma	29.9	MUC16 VEGFA
4	adenomyosis	29.5	MUC16 PRL VEGFA
5	neonatal ovarian cyst	12.1
6	malignant ovarian cyst	12.1
7	mccune-albright syndrome	11.3
8	fraser-like syndrome	10.9
9	aromatase deficiency	10.9
10	bleeding disorder, platelet-type, 19	10.9
11	autoimmune oophoritis	10.9
12	lipedematous scalp	10.9
13	opisthorchiasis	10.6	AFP MUC16
14	adenomatoid tumor	10.6	AFP MUC16
15	endodermal sinus tumor	10.6	AFP MUC16
16	hydrocele	10.6	AFP VEGFA
17	testicular granulosa cell tumor	10.6	AFP FOXL2
18	juvenile type testicular granulosa cell tumor	10.5	AFP FOXL2
19	peliosis hepatis	10.5	AFP VEGFA
20	primary peritoneal carcinoma	10.5	MUC16 VEGFA
21	telangiectasis	10.5	AFP VEGFA
22	pericardial effusion	10.4	MUC16 VEGFA
23	sex cord-gonadal stromal tumor	10.4	AFP FOXL2
24	serous cystadenocarcinoma	10.4	MUC16 VEGFA
25	peripartum cardiomyopathy	10.4	PRL VEGFA
26	ovarian brenner tumor	10.4	MUC16 PRL
27	placental insufficiency	10.4	AFP VEGFA
28	granulosa cell tumor of the ovary	10.3	FOXL2 PRL
29	pituitary tumors	10.3	PRL VEGFA
30	vein disease	10.3	AFP PLAT
31	ovarian cancer	10.1
32	peritonitis	10.1
33	amenorrhea	10.0	NOBOX PRL
34	meningocele	10.0
35	hypothyroidism	10.0
36	reproductive system disease	9.9	FOXL2 NOBOX PRL
37	premature ovarian failure 1	9.9	FOXL2 NOBOX PRL
38	ectopic pregnancy	9.9
39	breast cancer	9.9
40	aging	9.9
41	leiomyoma	9.9
42	vaginitis	9.9
43	endotheliitis	9.9
44	gingivitis	9.8	PLAT SERPINB2
45	ovarian serous cystadenocarcinoma	9.8	MUC16 VEGFA
46	leiomyoma, uterine	9.8
47	ovarian hyperstimulation syndrome	9.8
48	hydronephrosis	9.8
49	cervicitis	9.8
50	endometriosis	9.8

Graphical network of the top 20 diseases related to Ovarian Cyst:

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Symptoms & Phenotypes for Ovarian Cyst

UMLS symptoms related to Ovarian Cyst:

pelvic pain

MGI Mouse Phenotypes related to Ovarian Cyst:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.43	PRL VEGFA AFP FOXL2 NOBOX PLAT
2	reproductive system	MP:0005389	9.1	PRL VEGFA AFP FOXL2 NOBOX PLAT

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Drugs & Therapeutics for Ovarian Cyst

Drugs for Ovarian Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 361)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Zinc

Approved, Investigational

Phase 4,Early Phase 1,Not Applicable

7440-66-6

23994

Orlistat

Approved, Investigational

Phase 4,Phase 2

96829-58-2

3034010

Pioglitazone

Approved, Investigational

Phase 4,Not Applicable,Early Phase 1

111025-46-8

4829

Simvastatin

Approved

Phase 4,Phase 3,Not Applicable

79902-63-9

54454

Metformin

Approved

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

657-24-9

14219 4091

Hydrocortisone

Approved, Vet_approved

Phase 4,Not Applicable,Early Phase 1

50-23-7

5754

Ganirelix

Approved

Phase 4,Early Phase 1

123246-29-7, 124904-93-4

25081094

Drospirenone

Approved

Phase 4,Phase 3,Phase 1,Not Applicable

67392-87-4

68873

Estradiol valerate

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

979-32-8

Progesterone

Approved, Vet_approved

Phase 4,Phase 3,Phase 1,Not Applicable,Early Phase 1

57-83-0

5994

Letrozole

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

112809-51-5

3902

Resveratrol

Approved, Experimental, Investigational

Phase 4,Phase 1,Not Applicable

501-36-0

445154

Estradiol

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

50-28-2

5757

Testosterone

Approved, Investigational

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

58-22-0

6013

Cyproterone Acetate

Approved, Investigational

Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable

427-51-0

Ethinyl Estradiol

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

57-63-6

5991

Polyestradiol phosphate

Approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1

28014-46-2

Exenatide

Approved, Investigational

Phase 4,Phase 3,Phase 2

141758-74-9

15991534

Hyaluronic acid

Approved, Vet_approved

Phase 4,Phase 1,Phase 2

9004-61-9

53477741

Danazol

Approved

Phase 4

17230-88-5

28417

Etoricoxib

Approved, Investigational

Phase 4

202409-33-4

123619

Hydroxocobalamin

Approved

Phase 4,Not Applicable

13422-51-0

11953898 44475014

Tamoxifen

Approved

Phase 4,Phase 3

10540-29-1

2733526

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Not Applicable,Early Phase 1

50-02-2

5743

Liraglutide

Approved

Phase 4

204656-20-2

44147092

Citalopram

Approved

Phase 4

59729-33-8

2771

Moxonidine

Approved, Investigational

Phase 4

75438-57-2

4810

Acarbose

Approved, Investigational

Phase 4,Not Applicable

56180-94-0

441184

Rosiglitazone

Approved, Investigational

Phase 4,Not Applicable

122320-73-4

77999

Leuprolide

Approved, Investigational

Phase 4,Phase 2,Not Applicable,Early Phase 1

53714-56-0

3911 657181

Epinephrine

Approved, Vet_approved

Phase 4,Not Applicable,Early Phase 1

51-43-4

5816

Acetylcysteine

Approved, Investigational

Phase 4,Phase 2,Phase 3,Not Applicable

616-91-1

12035

Medroxyprogesterone acetate

Approved, Investigational

Phase 4,Not Applicable

71-58-9

Alogliptin

Approved

Phase 4

850649-61-5

11450633

Menotropins

Approved

Phase 4,Phase 1,Phase 2

61489-71-2, 9002-68-0

5360545

Racepinephrine

Approved

Phase 4,Not Applicable,Early Phase 1

329-65-7

838

Desogestrel

Approved

Phase 4,Phase 3

54024-22-5

40973

Prednisolone

Approved, Vet_approved

Phase 4

50-24-8

5755

Methylprednisolone

Approved, Vet_approved

Phase 4

83-43-2

6741

Toremifene

Approved, Investigational

Phase 4

89778-26-7

3005573

Nitrous oxide

Approved, Vet_approved

Phase 4

10024-97-2

948

leucovorin

Approved, Nutraceutical

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable

58-05-9

143 6006

Vitamin D

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

1406-16-2

Citric Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

77-92-9

311

Melatonin

Approved, Nutraceutical, Vet_approved

Phase 4,Not Applicable

73-31-4

896

Vitamin D3

Approved, Nutraceutical

Phase 4,Phase 3,Not Applicable

67-97-0

6221 5280795

Ergocalciferol

Approved, Nutraceutical

Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

50-14-6

5280793

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1

59-30-3

6037

Nicotinamide

Approved, Investigational, Nutraceutical

Phase 4

98-92-0

936

Methylcobalamin

Approved, Experimental, Investigational, Nutraceutical

Phase 4,Not Applicable

13422-55-4

Interventional clinical trials:

(show top 50) (show all 550)

#	Name	Status	NCT ID	Phase	Drugs
1	The Impact on Ovarian Reserve After Single-port, Two-port, or Four-port Access Laparoscopic Ovarian Cyst Enucleation	Unknown status	NCT01631253	Phase 4
2	Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants	Unknown status	NCT02027337	Phase 4	20 mcg ethinylestradiol /3 mg drospirenone;20 mcg ethinylestradiol/3 mg drospirenone and Selmevit;30 mcg ethinylestradiol/3 mg drospirenone;30 mcg ethinylestradiol/3 mg drospirenone and Selmevit;35 mcg ethinylestradiol/2 mg cyproterone;35 mcg ethinylestradiol/2 mg cyproterone and Selmevit
3	Myoinositol for the Treatment of Ovarian and Psychiatric Disorder in Polycystic Ovary Syndrome (PCOS) Patients	Unknown status	NCT01246310	Phase 4
4	Metformin in Infertile PCOS Patients	Unknown status	NCT00501904	Phase 4	Metformin
5	the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome	Unknown status	NCT01752270	Phase 4	Diane-35 pretreatment;Diane-35 pretreatment
6	Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome	Unknown status	NCT01366391	Phase 4	Metformin
7	Endometrial Scratching During Laproscopic Ovarian Drilling in Subfertile PCOS Women	Unknown status	NCT02140398	Phase 4
8	Comparison Between GnRH Agonist and GnRH Antagonist Protocols of Ovarian Stimulation in PCOS Patients	Unknown status	NCT00417144	Phase 4	Arvekap 0.1mg (Triptorelin, Ipsen, France);Ganirelix 0.25mg (Orgalutran, Organon, The Netherlands)
9	Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)	Unknown status	NCT00378729	Phase 4	Metformin and FSHr
10	Metformin and Gestational Diabetes in High-risk Patients: a RCTs	Unknown status	NCT00883259	Phase 4	Metformin
11	The Effect of Weight Loss on Anti-Müllerian Hormone Levels in Women With Polycystic Ovary Syndrome (PCOS)	Unknown status	NCT01475019	Phase 4	Orlistat;Sibutramine
12	Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS	Unknown status	NCT00461643	Phase 4	Clomiphene citrate, metformin, metformin plus clomiphene citrate, gonadotropins
13	The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cyst	Completed	NCT00713778	Phase 4
14	A Random Clinical Trial (RCT) of the Impact of Electrocoagulation on Ovarian Reserve	Completed	NCT00746278	Phase 4
15	Clinical Evaluation of Furocyst in Patients With Poly Cystic Ovary Syndrome	Completed	NCT02789488	Phase 4
16	The Role of Estrogen in Luteinizing Hormone Surge and Ovulation	Completed	NCT01999569	Phase 4	Letrozole
17	Danazol Treatment in Endometriosis Women Before IVF	Completed	NCT01779232	Phase 4	Danazol;placebo
18	Pain Post Abdominal Laparoscopy Prevention With Arcoxia	Completed	NCT00565682	Phase 4	etoricoxib 120 mg
19	FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women	Completed	NCT02674178	Phase 4
20	Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study	Completed	NCT01021579	Phase 4	Metformin plus Placebo;Metfomin plus Simvastatin
21	The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination	Completed	NCT01219101	Phase 4	clomiphene citrate with ethinyl esteradiol;clomiphene citrate with plasebo
22	Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome	Completed	NCT03122041	Phase 4	Sitagliptin
23	Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss	Completed	NCT02941445	Phase 4	sitagliptin and metformin;Metformin
24	The Effect of Metformin on Different Hormones in PCOS Patients	Completed	NCT02568488	Phase 4	Metformin
25	Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome	Completed	NCT02483299	Phase 4	Metformin;Glucophage tablets and Victoza
26	Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS	Completed	NCT02352597	Phase 4	phytoestrogen;estradiol valerate;clomiphene citrate
27	PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome	Completed	NCT02187250	Phase 4	metformin;liraglutide;roflumilast
28	PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome	Completed	NCT02037672	Phase 4	metformin;metformin and roflumilast
29	Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin	Completed	NCT01911468	Phase 4	metformin;liraglutide;metformin and liraglutide
30	Polycystic Ovary Syndrome and Liraglutide	Completed	NCT01899430	Phase 4	liraglutide;metformin
31	Vitamin D Treatment, Pharmacogenetics and Glucose Metabolism	Completed	NCT01721915	Phase 4	Vitamin D supplementation;Placebo
32	Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women	Completed	NCT01675310	Phase 4	medical nutrition therapy + metformin
33	hMG or Recombinant FSH on OHSS Prevention in PCOS Patients Undergoing IVF	Completed	NCT01365936	Phase 4	HMG;rFSH
34	The Effect of a Liraglutide on IVF in Obese PCOS	Completed	NCT03353948	Phase 4	MET;COMBI
35	Oral Contraceptive and Cardiovascular Risk in PCOS	Completed	NCT00593294	Phase 4	OC - Drospirenone plus Ethynylestradiol
36	The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS	Completed	NCT02866786	Phase 4	Metformin;ethinyl estradiol and cyproterone acetate
37	Metformin and Oral Contraceptives in PCOS	Completed	NCT00451568	Phase 4	Metformin;Desorelle
38	The Effects of Vitamin D on Transforming Growth Factor-beta1 in Polycystic Ovary Syndrome	Completed	NCT02460380	Phase 4	Vitamin D3
39	Trial With Metformin in Women With Polycystic Ovary Syndrome	Completed	NCT02280057	Phase 4	Metformin;Placebo
40	N-acetyl Cysteine for Ovulation Induction in Clomiphene Citrate Resistant Polycystic Ovary Syndrome	Completed	NCT02239107	Phase 4	N-Acetyl cysteine
41	LIPT - Liraglutide in Polycystic Ovary Syndrome	Completed	NCT02073929	Phase 4	Liraglutide;placebo
42	The Effect of Cipralex on Quality of Life, Adrenal Activity Glucose Metabolism, Physical and Mental Health in PCOS	Completed	NCT01961180	Phase 4	Cipralex;Placebo
43	Comparison of Alogliptin Versus Alogliptin and Pioglitazone on Insulin Resistance of Metformin Treated Women With PCOS	Completed	NCT02683226	Phase 4	Vipdomet;Incresync
44	Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome	Completed	NCT01540747	Phase 4
45	Polycystic Ovary Syndrome - Improving Outcomes	Completed	NCT01504321	Phase 4	Moxonidine;Placebo
46	Low Dose OC Therapy in Women With Polycystic Ovary Syndrome (PCOS): Impact of BMI on Hyperandrogenism	Completed	NCT01360996	Phase 4	3 mg DRSP/20 μg EE
47	Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)	Completed	NCT01279512	Phase 4	Metformin;Acarbose
48	Effect of Nicotinic Acid on Cardiovascular Risks Indices in Polycystic Ovary Syndrome	Completed	NCT01118598	Phase 4	tredaptive (nicotinic acid/ laropiprant);placebo
49	Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women	Completed	NCT01115140	Phase 4	metformin plus placebo;Metformin plus folic acid;placebo plus folic acid;placebo alone
50	Short-term Structured Exercise Training Program Plus Diet Intervention in Patients With Polycystic Ovary Syndrome (PCOS)	Completed	NCT01004068	Phase 4	Clomiphene citrate

Search NIH Clinical Center for Ovarian Cyst

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Genetic Tests for Ovarian Cyst

Genetic tests related to Ovarian Cyst:

#	Genetic test	Affiliating Genes
1	Ovarian Cyst ²⁹

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Anatomical Context for Ovarian Cyst

MalaCards organs/tissues related to Ovarian Cyst:

⁴¹

Ovary, Liver, Bone, Brain, Heart, Prostate, Endothelial

Sources

Publications for Ovarian Cyst

Articles related to Ovarian Cyst:

(show top 50) (show all 634)

#	Title	Authors	Year
1	The effects of sclerotherapy with 5% trichloroacetic acid on the cyst diameter and ovarian tissue in the rat ovarian cyst model. ( 29564948 )	ArtaA9 G....Akyol A.	2018
2	Vaginal bleeding and a giant ovarian cyst in an infant with 21-hydroxylase deficiency. ( 29252197 )	A9ahin N.M....Aycan Z.	2018
3	Omental fat necrosis without torsion mimicking ovarian cyst torsion. ( 29685724 )	Yi S.W.	2018
4	Ovarian cyst removal influences ovarian reserve dependent on histology, size and type of operation. ( 29806554 )	Henes M....Lawrenz B.	2018
5	A Giant Ovarian Cyst in an Adolescent. ( 29731358 )	Corrias F....Barbi E.	2018
6	High Frequency of Ovarian Cyst Development in Vhl<sup>2B/+</sup>;Snf5<sup>+/-</sup> Mice. ( 29684361 )	Kuwahara Y....Weissman B.E.	2018
7	Impending abdominal compartment syndrome from a giant ovarian cyst torsion. ( 28922702 )	Kim T.J....Zobair K.	2017
8	Case Report of Clitoral Hypertrophy in 2 Extremely Premature Girls With an Ovarian Cyst. ( 28931575 )	NerrAc A.L....Nivot-Adamiak S.	2017
9	Performance of ovarian cyst fluid fine-needle aspiration cytology. ( 28834408 )	Zhou A.G....Vandenbussche C.J.	2017
10	Haemoperitoneum due to ruptured ovarian cyst in a 13-year-old girl with factor V deficiency- A case report. ( 28138193 )	Aslam S.L....Fareeduddin M.	2017
11	Laparoscopic Management of a Giant Ovarian Cyst in a Premenarchal Girl. ( 28104495 )	Hurni Y....Puligheddu C.	2017
12	A Wandering Abdominal Mass in a Neonate: An Enteric Duplication Cyst Mimicking an Ovarian Cyst. ( 28348910 )	Iijima S.	2017
13	Diagnostic accuracy of haptoglobin within ovarian cyst fluid as a potential point-of-care test for epithelial ovarian cancer: an observational study. ( 28755436 )	Mahyuddin A.P....Choolani M.	2017
14	Complete Laparoscopic Extirpation of a Giant Ovarian Cyst in an Adolescent. ( 28840047 )	Baradwan S....Sendy S.	2017
15	Presacral mass in the setting of an ovarian cyst and abdominal pain. ( 28659365 )	Gutierrez O....Olasky J.	2017
16	Enormous Ovarian Cyst. ( 29021455 )	Uni R....Takano H.	2017
17	Giant ovarian cyst masquerading as a massive ascites: a case report. ( 29258579 )	Yeika E.V....Fomengia J.N.	2017
18	Hemorrhage in a Fetal Ovarian Cyst. ( 28770146 )	Hassan R....Mazlin J.	2017
19	LncRNAs expression profiling in normal ovary, benign ovarian cyst and malignant epithelial ovarian cancer. ( 27941916 )	Wang H....Xu P.	2016
20	EP22.08: Personalised 3D model for fetal ovarian cyst: a case report. ( 27646615 )	Chen L.	2016
21	Unusual presentation of twisted ovarian cyst. ( 27134479 )	Mishra V.V....Choudhary S.	2016
22	Large ovarian cyst with torsion. ( 27531002 )	Mhayamaguru M....Amini R.	2016
23	Occasional finding of giant bladder diverticulum that simulated an ovarian cyst: A case report and literature review. ( 26787074 )	Braga A....Caccia G.	2016
24	Hydronephrosis caused by a giant ovarian cyst. ( 27564301 )	Kim H.Y....Ma S.K.	2016
25	Diagnostic potential of tumor DNA from ovarian cyst fluid. ( 27421040 )	Wang Y....Vogelstein B.	2016
26	Borderline Brenner tumors associated with ovarian cyst - case presentation. ( 27833989 )	Albu D.F....VA8duva C.C.	2016
27	Postoperative AMH reduction is not associated with reduced fecundity two years following ovarian cyst surgery. ( 27028572 )	Lind T....Rodriguez-Wallberg K.A.	2016
28	Rocuronium and sugammadex in a 3 days old neonate for draining an ovarian cyst. Neuromuscular management and review of the literature. ( 27343797 )	Carlos R.V....de Boer H.D.	2016
29	Torsion, infarction, and rupture of a nongravid uterus: a complication of a large ovarian cyst. ( 27251733 )	Yap F.Y....Tchelepi H.	2016
30	Poster 167 Ovarian Cyst Rupture as an Unusual Etiology for Hip Pain in a Young Female Runner: A Case Report. ( 27672931 )	Dona S.T....Nicola T.L.	2016
31	The improvement of hirsutism and the decrease of testosterone concentration in the peripheral blood serum after removing an endometrioid ovarian cyst. ( 27328515 )	SA8opieA8 R....Sajdak S.	2016
32	Role of benign ovarian cysts in the development of adenomyosis. ( 27570851 )	Alam S....Rauf F.	2016
33	Papillary Serous Carcinoma of the Peritoneum mimicking Ovarian cyst in Pregnancy. ( 27133555 )	Paul P.G....Radhika K.T.	2016
34	Hemolymphangioma of the broad ligament: A differential diagnosis for an ovarian cyst. ( 27558953 )	Sharpe A.N....Choudhary M.	2016
35	Large hemorrhagic ovarian cyst in postmenopausal patient with autosomal dominant polycystic kidney disease. ( 27795640 )	Mishra V.V....Aggarwal R.	2016
36	Appendix mucocele mimicking a complex ovarian cyst. ( 25931937 )	Demirci R.K....A9ner O.Z.	2015
37	Conservative management of a large neonatal ovarian cyst: a case report. ( 26023615 )	Aamir M....Sharma D.	2015
38	Percutaneous Drainage of a Rapidly Enlarging Simple Ovarian Cyst in the Third Trimester. ( 26444478 )	Bannon L.C....Porter K.B.	2015
39	Giant Ovarian Cyst Masquerading as Massive Ascites in an 11-Year-Old. ( 26236528 )	Mohammed Elhassan S.A....El-Makki A.	2015
40	Prenatal and postnatal ultrasonographic findings of the torsioned ovarian cyst: a case report and brief literature review. ( 25785337 )	Ogul H....Kantarci M.	2015
41	Unusual Presentation of an Ovarian Cyst: Successful Laparoscopic Excision. ( 27678805 )	Jones A.S....Griffiths A.	2015
42	Telelap Alf-X-Assisted Laparoscopy for Ovarian Cyst Enucleation: Report of the First 10 Cases. ( 25987523 )	Gueli Alletti S....Scambia G.	2015
43	Complex fetal ovarian cyst. ( 25911726 )	Okumura M....Zugaib M.	2015
44	Ovarian Cyst Aspiration in the Neonate: Minimally Invasive Surgery. ( 26148782 )	Cho M.J....Kim S.C.	2015
45	Post-Operative Analgesia after Laparoscopic Ovarian Cyst Resection: Double Blind Multicenter Randomized Control trial comparing Intraperitoneal Nebulization and Peritoneal Instillation of Ropivacaine. ( 25820113 )	Catenacci S.S....Ingelmo P.M.	2015
46	Transfundal puncture of a large ovarian cyst with hysteroscopic and ultrasonographic guidance. ( 25999768 )	Zolnierczyk P....Sawicki W.	2015
47	Comparison of anti-mullerian hormone level in non-endometriotic benign ovarian cyst before and after laparoscopic cystectomy. ( 26000005 )	Amooee S....Ravanfar P.	2015
48	Ovarian Cyst Saline Distention to Enhance Dissection Planes Upon Cystectomy. ( 27678824 )	Silva-Melendez P.E....Burgos-Rodriguez R.	2015
49	Neurogenic Ovarian Cyst--A Rare, Monodermal Teratoma. ( 26261871 )	Williams K....Chernetsova E.	2015
50	Torsed large prenatally detected foetal ovarian cyst. ( 25671519 )	Antonakopoulos N....Loutradis D.	2015

Sources

Genes for Ovarian Cyst

Genes related to Ovarian Cyst (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	MUC16	Mucin 16, Cell Surface Associated	Protein Coding	25.04	Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	1696873 10430190 17641444 (more) 10826587 9228498 11352859
2	FOXL2	Forkhead Box L2	Protein Coding	20.43	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	AFP	Alpha Fetoprotein	Protein Coding	20.39	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	16.88	GeneCards inferred via : Publications (show sections)
5	NOBOX	NOBOX Oogenesis Homeobox	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
6	PRL	Prolactin	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
7	SERPINB2	Serpin Family B Member 2	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
8	SLC25A13	Solute Carrier Family 25 Member 13	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
9	GSTP1	Glutathione S-Transferase Pi 1	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
10	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)

Sources

Variations for Ovarian Cyst

ClinVar genetic disease variations for Ovarian Cyst:

⁶

#	Gene	Variation	Type	Significance	SNP ID	Assembly	Location
1		46;XX;ins(5;6)(p13;p24p25)dn	Translocation	Pathogenic

Sources

Expression for Ovarian Cyst

Search GEO for disease gene expression data for Ovarian Cyst.

Sources

Pathways for Ovarian Cyst

Pathways related to Ovarian Cyst according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Fluid shear stress and atherosclerosis ³⁷	11.27	GSTP1 PLAT VEGFA
2	Endochondral Ossification ¹	11.13	PLAT VEGFA
3	Cell adhesion_Plasmin signaling ²²	10.95	PLAT VEGFA
4	NOTCH1 regulation of human endothelial cell calcification ¹	10.41	PLAT VEGFA
5	Dissolution of Fibrin Clot ⁶⁶	9.74	PLAT SERPINB2

Sources

GO Terms for Ovarian Cyst

Cellular components related to Ovarian Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.5	AFP GSTP1 MUC16 PLAT PRL SERPINB2
2	extracellular space	GO:0005615	9.17	AFP GSTP1 MUC16 PLAT PRL SERPINB2

Biological processes related to Ovarian Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	response to nutrient levels	GO:0031667	9.26	GSTP1 PRL
2	lactation	GO:0007595	9.16	PRL VEGFA
3	ovarian follicle development	GO:0001541	8.96	FOXL2 VEGFA
4	fibrinolysis	GO:0042730	8.62	PLAT SERPINB2

Sources

Sources for Ovarian Cyst

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia