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MCID: OVR046
MIFTS: 47

Ovarian Cyst

Categories: Cancer diseases, Reproductive diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Ovarian Cyst

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MalaCards integrated aliases for Ovarian Cyst:

Name: Ovarian Cyst 12 6 15
Ovarian Cysts 54 42 15 71

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:5119
ICD9CM 34 620.2
ICD10 32 N83.2
UMLS 71 C0029513 C0029927
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Summaries for Ovarian Cyst

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MedlinePlus : 42 The ovaries are part of the female reproductive system. They produce a woman's eggs and make female hormones. Ovarian cysts are fluid-filled sacs in or on an ovary. They usually form during ovulation, when the ovary releases an egg. They are usually harmless and go away by themselves. Most women have them sometime during their lives. Most ovarian cysts are small and don't cause symptoms. Women may not find out that they have them until they have a pelvic exam. If there are symptoms, they may include Pressure Bloating Swelling Pain in the lower abdomen, on the side where the cyst is If your health care provider finds a cyst, you may be able to wait to see if it gets bigger. You may need surgery if you have pain, are past menopause, or if the cyst does not go away. If a cyst bursts or causes bleeding, you should get medical help right away. Birth control pills can help prevent new cysts. Rarely, ovarian cysts can become cancerous. This risk increases as you get older. A health problem that involves ovarian cysts is polycystic ovary syndrome (PCOS). Women with PCOS can have high levels of male hormones, irregular or no periods, and small ovarian cysts. Dept. of Health and Human Services Office on Women's Health

MalaCards based summary : Ovarian Cyst, also known as ovarian cysts, is related to malignant ovarian cyst and corpus luteum cyst, and has symptoms including pelvic pain An important gene associated with Ovarian Cyst is MUC16 (Mucin 16, Cell Surface Associated), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and GnRH secretion. The drugs Ethinyl Estradiol and Etoricoxib have been mentioned in the context of this disorder. Affiliated tissues include ovary, breast and pituitary, and related phenotypes are endocrine/exocrine gland and liver/biliary system

Disease Ontology : 12 An ovarian disease that is characterized by the presence of a fluid-filled sac and is located in the ovary.

Wikipedia : 74 An ovarian cyst is a fluid-filled sac within the ovary. Often they cause no symptoms. Occasionally they... more...

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Related Diseases for Ovarian Cyst

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Diseases in the Ovarian Cyst family:

Malignant Ovarian Cyst

Diseases related to Ovarian Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 366)
# Related Disease Score Top Affiliating Genes
1 malignant ovarian cyst 34.1 WFDC2 IGFBP2
2 corpus luteum cyst 32.9 MUC16 GNRH1 FOXL2 AFP
3 carney complex variant 31.5 PRL GNAS CNC2
4 cystadenoma 31.3 MUC16 GNAS AFP
5 precocious puberty 30.9 GNRH1 GNAS CYP19A1
6 ovarian serous cystadenocarcinoma 30.6 VEGFA MUC16 GNAS ESR2
7 amenorrhea 30.5 PRL GNRH1 FOXL2 CYP19A1
8 teratoma 30.5 CGA AMH AFP
9 leiomyoma 30.5 GNRH1 ESR2 CYP19A1
10 cystadenocarcinoma 30.4 VEGFA MUC16 ESR2
11 cystadenofibroma 30.3 MUC16 AFP
12 juvenile type testicular granulosa cell tumor 30.3 GNAS FOXL2 AFP
13 hyperandrogenism 30.2 PRL GNRH1 CYP19A1
14 goiter 30.1 VEGFA PRL GNAS
15 hypothyroidism 30.1 VEGFA PRL GNRH1 GNAS CGA
16 endometrial hyperplasia 30.0 VEGFA ESR2 CYP19A1
17 ectopic pregnancy 30.0 VEGFA PAEP GNRH1 CGA AFP
18 triploidy 30.0 CGA AFP
19 congenital hypothyroidism 30.0 PRL GNAS AFP
20 lipoid congenital adrenal hyperplasia 30.0 PRL GNRH1 CYP19A1 AMH
21 leiomyoma, uterine 29.9 MUC16 GNRH1 ESR2 CYP19A1
22 serous cystadenocarcinoma 29.9 VEGFA MUC16 ESR2
23 mccune-albright syndrome 29.9 PRL GNAS CYP19A1 AMH
24 ovary adenocarcinoma 29.9 VEGFA MUC16 MIR135A1 GNAS
25 myoma 29.8 MUC16 GNRH1 CYP19A1 AMH
26 placenta disease 29.7 VEGFA CGA AFP
27 hyperprolactinemia 29.7 PRL GNRH1 GNAS CGA
28 ductal carcinoma in situ 29.6 VEGFA ESR2 CYP19A1
29 adenomyosis 29.5 VEGFA PRL GNRH1 ESR2 CYP19A1
30 ovarian hyperstimulation syndrome 29.4 VEGFA GNRH1 CYP19A1 CGA AMH
31 pituitary gland disease 29.3 PRL GNRH1 GNAS CGA
32 infertility 29.3 PRL PAEP GNRH1 ESR2 CYP19A1 CGA
33 pituitary tumors 29.3 PRL GNAS CNC2
34 hyperthyroidism 29.3 PRL GNAS CGA
35 polycystic ovary syndrome 29.3 PRL GNRH1 CYP19A1 CGA AMH
36 estrogen excess 29.3 PRL GNRH1 FOXL2 ESR2 CYP19A1
37 ovarian disease 29.2 VEGFA PRL MUC16 MIR145 MIR135A1 IGFBP2
38 endometriosis 29.1 VEGFA PAEP MUC16 MIR145 GNRH1 ESR2
39 anovulation 29.1 PRL GNRH1 CYP19A1 CGA AMH
40 gynecomastia 28.9 PRL GNRH1 ESR2 CYP19A1 CGA
41 endometrial cancer 28.7 VEGFA PAEP MUC16 MIR145 GNRH1 ESR2
42 endometriosis of ovary 28.5 MIR145 GNRH1 ESR2 CYP19A1 AMH
43 premature ovarian failure 1 28.2 PRL PAEP GNRH1 FOXL2 ESR2 CYP19A1
44 ovarian cancer 28.1 WFDC2 VEGFA PAEP MUC16 MIR145 MIR135A1
45 neonatal ovarian cyst 12.5
46 aromatase deficiency 11.7
47 fraser-like syndrome 11.6
48 bleeding disorder, platelet-type, 19 11.2
49 autoimmune oophoritis 11.2
50 lipedematous scalp 11.2

Graphical network of the top 20 diseases related to Ovarian Cyst:



Diseases related to Ovarian Cyst
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Symptoms & Phenotypes for Ovarian Cyst

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UMLS symptoms related to Ovarian Cyst:


pelvic pain

MGI Mouse Phenotypes related to Ovarian Cyst:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.96 AFP AMH CGA CYP19A1 ESR2 FOXL2
2 liver/biliary system MP:0005370 9.76 AFP CYP19A1 ESR2 GNAS GNRH1 IGFBP2
3 neoplasm MP:0002006 9.5 AFP AMH ESR2 GNAS GNRH1 PRL
4 reproductive system MP:0005389 9.28 AFP AMH CGA CYP19A1 ESR2 FOXL2
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Drugs & Therapeutics for Ovarian Cyst

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Drugs for Ovarian Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 117)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
2
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
3
Danazol Approved Phase 4 17230-88-5 28417
4
Drospirenone Approved Phase 4 67392-87-4 68873
5
Dienogest Approved Phase 4 65928-58-7
6
Letrozole Approved, Investigational Phase 4 112809-51-5 3902
7
Heparin Approved, Investigational Phase 4 9005-49-6 46507594 772
8
Leuprolide Approved, Investigational Phase 4 53714-56-0 657181 3911
9
tannic acid Approved Phase 4 1401-55-4
10
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
11 Anti-Inflammatory Agents Phase 4
12 Analgesics, Non-Narcotic Phase 4
13 Cyclooxygenase 2 Inhibitors Phase 4
14 Cyclooxygenase Inhibitors Phase 4
15 Analgesics Phase 4
16 Antirheumatic Agents Phase 4
17 Anti-Inflammatory Agents, Non-Steroidal Phase 4
18 Estrogen Receptor Antagonists Phase 4
19 Estrogen Antagonists Phase 4
20 Drospirenone and ethinyl estradiol combination Phase 4
21 Fenugreek Phase 4
22 Fenugreek seed meal Phase 4
23 Aromatase Inhibitors Phase 4
24 Contraceptive Agents, Male Phase 4
25 Fibrinolytic Agents Phase 4
26 Anticoagulants Phase 4
27 calcium heparin Phase 4
28 Mineralocorticoids Phase 4
29 Mineralocorticoid Receptor Antagonists Phase 4
30 diuretics Phase 4
31 Diuretics, Potassium Sparing Phase 4
32 Antineoplastic Agents, Hormonal Phase 4
33
Norgestimate Approved, Investigational Phase 2, Phase 3 35189-28-7 6540478
34
Ropivacaine Approved Phase 3 84057-95-4 71273 175805
35
Morphine Approved, Investigational Phase 3 57-27-2 5288826
36 Cinnamon Approved Phase 3
37
Prednisolone phosphate Approved, Vet_approved Phase 2, Phase 3 302-25-0
38
Salicylic acid Approved, Investigational, Vet_approved Phase 2, Phase 3 69-72-7 338
39
Methylprednisolone Approved, Vet_approved Phase 2, Phase 3 83-43-2 6741
40
Methylprednisolone hemisuccinate Approved Phase 2, Phase 3 2921-57-5
41
Clotrimazole Approved, Vet_approved Phase 2, Phase 3 23593-75-1 2812
42
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3 22916-47-8 4189
43
Prednisolone Approved, Vet_approved Phase 2, Phase 3 50-24-8 5755
44 Prednisolone acetate Approved, Vet_approved Phase 2, Phase 3 52-21-1
45
Aspirin Approved, Vet_approved Phase 2, Phase 3 50-78-2 2244
46
Buserelin Approved, Investigational Phase 3 57982-77-1
47
Prednisolone hemisuccinate Experimental Phase 2, Phase 3 2920-86-7
48 Anesthetics, Local Phase 3
49 Methylprednisolone Acetate Phase 2, Phase 3
50 Salicylates Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 104)
# Name Status NCT ID Phase Drugs
1 The Impact on Ovarian Reserve After Single-port, Two-port, or Four-port Access Laparoscopic Ovarian Cyst Enucleation Unknown status NCT01631253 Phase 4
2 A Random Clinical Trial of the Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cyst Completed NCT00746278 Phase 4
3 The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Exc Completed NCT00713778 Phase 4
4 FSH/LH Ratio as a Predictor of IVF Outcome in Young and Older Women Completed NCT02674178 Phase 4
5 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4 etoricoxib 120 mg
6 Treatment With Danazol Before Controlled Ovarian Hyperstimulation in Women With Endometriosis Undergoing IVF Completed NCT01779232 Phase 4 Danazol;placebo
7 Efficacy and Safety of Furocyst in Patients With Poly Cystic Ovary Syndrome Completed NCT02789488 Phase 4
8 The Role of Estrogen in Luteinizing Hormone Surge and Ovulation Completed NCT01999569 Phase 4 Letrozole
9 the Effect of Unfractionated Heparin in Treatment of IVF-ET Failure Completed NCT01214772 Phase 4 heparin
10 Which do You Think is the Best Treatment Choice in Primary Dysmenorrhea? Completed NCT03124524 Phase 4 estradiol valerate/dienogest;ethinylestradiol and drospirenone
11 Comparative Study Between ICSI Results in Transvaginal Ultrasound Guided Embryo Transfer and Transabdominal Ultrasound Guided Embryo Transfer Not yet recruiting NCT03683043 Phase 4 Long GnRH agonist protocol
12 Can Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist Withstand When Administered at Different Points in the Menstrual Cycle? Not yet recruiting NCT04060992 Phase 4 Elagolix 200 MG Oral Tablet [Orilissa]
13 Are the Combined Oral Contraceptive Pills Needed for Management of the Simple Ovarian Cysts in Reproductive Women? (Randomized Controlled Study) Unknown status NCT03357640 Phase 2, Phase 3 combined oral contraceptive pills
14 Do Peritoneal Nebulization of Ropivacaine Reduce the Use of Morphine After Short Gynecologic Laparoscopic Surgery? Completed NCT01142622 Phase 3 Ropivacaine nebulization;Ropivacaine instillation
15 Additional Benefit of Hemostatic Sealant in Preserving Ovarian Reserve During Laparoscopic Ovarian Cystectomy: a Randomized Controlled Trial Completed NCT01857466 Phase 3
16 A Single Center, Randomized, Investigator-initiated Phase III Trial to Evaluate the Efficacy of Preservation of Ovarian Function and Hemostasis, and Its Safety of Surgiguard@ During Laparoscopic Ovarian Cystectomy Completed NCT03374397 Phase 3 Surgiguard
17 Single Port Laparoscopy Versus Conventional Laparoscopy for Benign Adnexal Disease - A Randomized Controlled Trial. Completed NCT01288599 Phase 3
18 A Phase III, 18-Month, Extension Study to Evaluate the Safety of Asoprisnil in Subjects With Uterine Leiomyomata Completed NCT00156208 Phase 3 Asoprisnil;Asoprisnil
19 A Phase 3, 12-Month, Extension Study to Evaluate the Safety of Asoprisnil in Subjects With Uterine Leiomyomata Completed NCT00156195 Phase 3 Asoprisnil;Asoprisnil
20 Placebo-controlled Evaluation of the Homeopathic Drug BRN01 for the Treatment of Hot Flashes in Women With Non Metastatic Breast Cancer Treated by Adjuvant Hormonal Therapy Completed NCT01246427 Phase 3 BRN01;Placebo
21 The Effects of Oral Cinnamon Extract on Menstrual Cyclicity in PolyCystic Ovary Syndrome Completed NCT01483118 Phase 3 Cinnamon Extract
22 The Value of Addition of Prednisolone to Acetylsalicylic Acid Prior to Embryo Transfer in Patients With First ICSI Cycles: A Randomized Controlled Trial Completed NCT03503227 Phase 2, Phase 3 prednisolone;Acetyl Salicylic acid
23 Comparative Study Between Minidose Long Protocol and Microdose Flare Protocol in Controlled Ovarian Hyperstimulation for Poor Responders in ICSI Cycles Completed NCT02342197 Phase 3 Decapeptyl
24 Gonadotrophin Releasing Hormone Agonist for Dual Trigger in in Vitro Fertilization and for Luteal Phase Support in Frozen-thawed Embryo Transfer Recruiting NCT04064840 Phase 3 IVF: Decapeptyl and hCG;FET: Decapeptyl;IVF: hCG and normal saline;FET: Normal Saline
25 A Prospective, Controlled, Randomized, Multi-Center, Pivotal Study Evaluating the Safety and Efficacy of AdhexilTM in Prevention And/Or Reduction of Adhesions in Gynecology Surgery Suspended NCT00865488 Phase 3
26 Prospective, Randomized Open Trial to Evaluate the Efficacy of an Ovarian Stimulation Protocol Based on FSH Receptor Genotype Suspended NCT00749853 Phase 3 follicle stimulating hormone;follicle stimulating hormone
27 The Effects of ß1-receptor Blockade and α1-adrenergic Agonist on the Kinetics of Lactated Ringer's Solution During Surgery Completed NCT01431612 Phase 1, Phase 2 Esmolol administration;Phenylephrine infusion;Lactated Ringer´s solution
28 The Use of Surgicel in Preventing Recurrence of Ovarian Endometriomas During Laparoscopic Surgery Completed NCT02947724 Phase 2 SURGICEL®
29 Efficacy of Leptin in Severe Insulin Resistance: A Pilot Study Completed NCT00027456 Phase 2 Leptin A-100
30 Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy Completed NCT00025883 Phase 2 Metreleptin
31 Effects of the Aromatase Inhibitor Letrozole on Pubertal Progression and Indices of Bone Turnover in Girls With Precocious Puberty and McCune-Albright Syndrome (MAS) Completed NCT00006174 Phase 1 Letrozole
32 Prognosis and Long Term Pubertal Outcome of Girls Previously Diagnosed With a Prenatal Ovarian Cyst Unknown status NCT02482467
33 Monitoring Ovarian Cysts in Pregnancy Unknown status NCT03440931
34 The Impact of Surgical Treatment of Ovarian Endometriomas on Ovarian Reserve: a Randomised Controlled Trial of Laparoscopic Ovarian Cystectomy Versus Cyst Ablation - a Pilot Study Unknown status NCT01425333
35 Predicting Ovarian Response in Artificial Insemination With Low Stimulation Unknown status NCT01662180 Follicle Stimulating Hormone
36 Laparoscopy-assisted Ovarian Cystectomy: NEW APPROCH Unknown status NCT03370952
37 Mediterranean Diet Versus Hypocaloric Diet: What is the Best Choice for the Treatment of Polycystic Ovary Syndrome (PCOS)? Unknown status NCT02397174
38 Mediterranean Diet: A New Nutritional Approach for the Treatment of Normal Weight Women With Polycystic Ovary Syndrome (PCOS)? Unknown status NCT02396264
39 The Effects of Using Microfluidic Separation Sperm Selection for Unexplained Infertility(UEI) and Reccurrent Implantation Failure(RIF) Unknown status NCT03355937
40 Evaluating the Effectivenemss of Percutaneous Tibial Nerve Stimulation as a Treatment for Tenesmus in Patients With Pelvic Floor Disorders Unknown status NCT02270190
41 Operative Treatment of Endometriosis Patients in Turku University Hospital Unknown status NCT01849354
42 The Efficacy of Extracorporal Shock Wave Therapy on Symptoms Relief in Patients With Chronic Non-bacterial Prostatitis / Chronic Pelvic Pain Syndrome Unknown status NCT01714830
43 A New Algorithm to Predict Ovarian Age Combining Clinical, Biochemical and 3D-ultrasonographic Parameters: OvAge Unknown status NCT02086318
44 Comparison Between Abstention and Intrauterine Aspiration in the Treatment of Anechoic Fetal Ovarian Cysts to Prevent Ovarian Torsion Completed NCT00222066
45 3-dimensional Versus 2-dimensional Laparoscopy Of Ovarian Cyst (LOOC): a Randomized Controlled Trial Completed NCT03453333
46 The Effect of Surgery for Non Endometriosic Ovarian Cysts on Ovarian Reserve : A Prospective Study Completed NCT02852447
47 Mesial Incision for Laparoscopic Dermoid Cystectomy: a New Safe and Fertility-sparing Technique Completed NCT01590030
48 Transvaginal Ultrasound Training for the Obstetrics and Gynecology Resident: A Multi-Site Randomized Controlled Trial of Educational DVD Completed NCT02890914
49 Metabolic and Endocrine Status in Women With Prior Preterm Birth. A Cross Sectional, Case- Control Study Completed NCT01355536
50 Prospective Multicenter Study in Patients With a Tumor Benign Ovarian Presumed on the Use of Algorithms Such as Roma and RMI (Risk of Malignancy Index) and Tumor Markers Such as CA125 (Cancer Antigen 125) and HE4 (Human Epididymal Protein 4) Completed NCT02326064

Search NIH Clinical Center for Ovarian Cyst

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Genetic Tests for Ovarian Cyst

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Anatomical Context for Ovarian Cyst

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The Foundational Model of Anatomy Ontology organs/tissues related to Ovarian Cyst:

19
Ovary

MalaCards organs/tissues related to Ovarian Cyst:

40
Ovary, Breast, Pituitary, Uterus, Colon, Thyroid, Testes
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Publications for Ovarian Cyst

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Articles related to Ovarian Cyst:

(show top 50) (show all 4708)
# Title Authors PMID Year
1
NATURALLY-OCCURRING AUTOANTIBODIES TO HUMAN CHORIONIC GONADOTROPIN AND ITS SUBUNITS IN OVARIAN CYST PATIENTS. 61 42
32141859 2020
2
Susceptibility-weighted MR sequence for the evaluation of ovarian masses with torsion. 42
32208978 2020
3
Dermoid cyst with secretion of CA 19-9 detected by 18F-FDG PET/CT: A case report. 42
32150047 2020
4
Reproductive disturbances in multiple neuroendocrine tumor syndromes. 61 54
19737912 2009
5
Genetic and clinical spectrum of aromatase deficiency in infancy, childhood and adolescence. 61 54
19844120 2009
6
The impact of unabated stimulation by human chorionic gonadotropin on the steroid hormone environment of pregnant rats and the spontaneous expression of ovarian cysts in female progeny. 61 54
18481228 2008
7
Precocious pseudopuberty due to autonomous ovarian cysts: a report of ten cases and long-term follow-up. 61 54
18477555 2008
8
Involvement of plasma progesterone, oestradiol-17beta and cortisol in ovulatory response to gonadotropin-releasing hormone in dairy cows with cystic follicles. 54 61
17635773 2007
9
McCune-Albright syndrome and disorders due to activating mutations of GNAS1. 54 61
17937059 2007
10
Myxedema ascites with an extremely elevated CA125 Level: a case report. 54 61
17641444 2007
11
Obligatory roles for follicle-stimulating hormone (FSH), estradiol and androgens in the induction of small polyfollicular ovarian cysts in hypophysectomized immature rats. 61 54
17873331 2007
12
Association between milk production and treatment response of ovarian cysts in lactating dairy cows using the Ovsynch protocol. 61 54
16650468 2006
13
Insulin-like growth factor binding protein-2 stimulates proliferation and activates multiple cascades of the mitogen-activated protein kinase pathways in NIH-OVCAR3 human epithelial ovarian cancer cells. 61 54
16357519 2006
14
Development of monoclonal and polyclonal antibodies and an ELISA for the determination of glycodelin in human serum, amniotic fluid and cystic fluid of benign and malignant ovarian tumors. 54 61
16033064 2005
15
Measurement of glycodelin A in fluids of benign ovarian cysts, borderline tumours and malignant ovarian cancer. 61 54
16033074 2005
16
No evidence of mutations in the P450 aromatase gene in patients with polycystic ovary syndrome. 61 54
15695318 2005
17
[Carney complex: a case report and literature review]. 54 61
15761519 2004
18
Intracystic evaluation of tumor markers in benign and malignant ovarian pathology. 61 54
12013118 2002
19
The development of an oocyte-containing follicle during gonadotrophin-releasing hormone agonist administration. 54 61
11473966 2001
20
Factors influencing serum CA125II levels in healthy postmenopausal women. 61 54
11352859 2001
21
Ovarian lesions in Carney complex: clinical genetics and possible predisposition to malignancy. 54 61
11095480 2000
22
Serum CA125 at 11-14 weeks of gestation in women with morphologically normal ovaries. 54 61
10826587 2000
23
Synergistic effects of insulin-like growth factor-I and human chorionic gonadotropin in the rat ovary. 61 54
10726907 2000
24
Insulin has a biphasic effect on the ability of human chorionic gonadotropin to induce ovarian cysts in the rat. 61 54
10459564 1999
25
Follow up of women with simple ovarian cysts detected by transvaginal sonography in the Tokyo metropolitan area. 54 61
10430190 1999
26
Differential expression of estrogen receptor-alpha and -beta messenger RNAs as a potential marker of ovarian carcinogenesis. 61 54
9850067 1998
27
Pretreatment with an oral contraceptive is effective in reducing the incidence of functional ovarian cyst formation during pituitary suppression by gonadotropin-releasing hormone analogues. 61 54
9866068 1998
28
CA-125 and carcinoembryonic antigen assay vs. cytodiagnostic experience in the classification of benign ovarian cysts. 61 54
9305384 1997
29
[A patient with bronchial asthma and mucoid impaction who presented with a high concentration of carcinoembryonic antigen in serum]. 61 54
9366164 1997
30
Inhibin assays of ovarian cyst liquid obtained by needle aspiration may allow differential diagnosis between functional and organic cysts. 61 54
9228498 1997
31
The behavior of follicle cysts formed after long-acting gonadotropin-releasing hormone analog administration in patients with polycystic ovarian syndrome. 54 61
9174850 1997
32
The assessment of value of transvaginal ultrasound for monitoring of gestational trophoblastic disease treatment. 61 54
9443032 1997
33
Serum levels of the tumour-associated trypsin inhibitor in patients with endometriosis. 61 54
8988701 1997
34
Increased insulin-like growth factor binding protein-2 (IGFBP-2) gene expression and protein production lead to high IGFBP-2 content in malignant ovarian cyst fluid. 54 61
8624265 1996
35
[Hydatidiform mole in Vietnam. The contribution of ultrasonography]. 54 61
7899773 1995
36
Persistent elevation of serum oestradiol levels by functional ovarian cysts despite effective pituitary desensitization with GnRH agonists. 61 54
8187299 1994
37
Hyperinsulinemia and human chorionic gonadotropin synergistically promote the growth of ovarian follicular cysts in rats. 54 61
1640871 1992
38
Serous ovarian cyst fluids contain high levels of endometrial placental protein 14. 54 61
1626182 1992
39
Circulating hormone concentrations in hypothyroid rats with induced polycystic ovaries. 54 61
1924408 1991
40
Effect of intracavitary radiotherapy on tumor-associated trypsin inhibitor (TATI) in patients with cervical and endometrial cancer. 61 54
2354815 1990
41
Measurement of CA125, carcinoembryonic antigen, and alpha-fetoprotein in ovarian cyst fluid: diagnostic adjunct to cytology. 61 54
1696873 1990
42
Levels of the neuropeptide phoenixin-14 and its receptor GRP173 in the hypothalamus, ovary and periovarian adipose tissue in rat model of polycystic ovary syndrome. 61
32505354 2020
43
Laparoscopic management of a degenerating cystic leiomyoma imitating an ovarian cyst: A case report. 61
32368506 2020
44
Characteristics and surgical invervention of ovarian torsion in pregnant compared with nonpregnant women. 61
32541500 2020
45
Antenatally detected abdominal cyst: Does cyst size and nature determine postnatal symptoms and outcome? 61
32521469 2020
46
Evaluation of the usefulness of laparoscopy in the diagnosis and treatment of adnexal pathologies in the pediatric population. 61
32489499 2020
47
[Retrospective evaluation of relevance of care in the management of presumed benign ovarian tumors]. 61
32243912 2020
48
A Five-Year Review of Ovarian Torsion Cases: Lessons Learnt. 61
32476769 2020
49
A mediastinal cyst with Mullerian differentiation in a patient with an ovarian cyst. 61
32540443 2020
50
A cystectomic technique with low risk of rupture for women with benign ovarian cyst. 61
32496929 2020
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Variations for Ovarian Cyst

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ClinVar genetic disease variations for Ovarian Cyst:

6 ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 46;XX;ins(5;6)(p13;p24p25)dnTranslocation Pathogenic 267851
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Expression for Ovarian Cyst

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Search GEO for disease gene expression data for Ovarian Cyst.
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Pathways for Ovarian Cyst

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Pathways related to Ovarian Cyst according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Glucocorticoid receptor regulatory network 1
11.35 PRL CGA AFP
2
GnRH secretion 36
11.14 GNRH1 ESR2 CGA
3
Ovarian steroidogenesis 36
10.84 GNAS CYP19A1 CGA
4
Hormone ligand-binding receptors 65
10.44 GNRH1 CGA
5
Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics 60
9.23 ESR2 CYP19A1
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GO Terms for Ovarian Cyst

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Cellular components related to Ovarian Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 WFDC2 VEGFA PRL MUC16 IGFBP2 GNRH1
2 extracellular region GO:0005576 9.4 WFDC2 VEGFA PRL PAEP MUC16 IGFBP2

Biological processes related to Ovarian Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 uterus development GO:0060065 9.16 FOXL2 CYP19A1
2 gonad development GO:0008406 8.96 CGA AMH
3 female pregnancy GO:0007565 8.92 PRL IGFBP2 GNRH1 GNAS

Molecular functions related to Ovarian Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.92 PRL GNRH1 CGA AMH
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Sources for Ovarian Cyst

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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