MCID: OVR047
MIFTS: 33

Ovarian Cystadenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystadenocarcinoma

MalaCards integrated aliases for Ovarian Cystadenocarcinoma:

Name: Ovarian Cystadenocarcinoma 12 15 73
Cystadenocarcinoma of the Ovary 12
Cystadenocarcinoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3605
NCIt 50 C5228
UMLS 73 C1096638

Summaries for Ovarian Cystadenocarcinoma

Disease Ontology : 12 An ovary adenocarcinoma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary : Ovarian Cystadenocarcinoma, also known as cystadenocarcinoma of the ovary, is related to cystadenocarcinoma and serous cystadenocarcinoma. An important gene associated with Ovarian Cystadenocarcinoma is ZNF217 (Zinc Finger Protein 217), and among its related pathways/superpathways are C-type lectin receptor signaling pathway and Long-term potentiation. Affiliated tissues include ovary, liver and appendix, and related phenotype is no phenotypic analysis.

Related Diseases for Ovarian Cystadenocarcinoma

Diseases related to Ovarian Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 cystadenocarcinoma 31.1 HRAS UBE4A ZNF217
2 serous cystadenocarcinoma 30.3 HRAS UBE4A ZNF217
3 urachal adenocarcinoma 30.1 GNAS KRAS
4 ovarian mucinous cystadenocarcinoma 11.2
5 ovarian clear cell cystadenocarcinoma 11.2
6 krukenberg carcinoma 10.3
7 mucinous cystadenocarcinoma 10.2
8 papillary cystadenocarcinoma 10.2
9 sigmoid neoplasm 10.2 HRAS KRAS
10 apocrine adenoma 10.2 HRAS KRAS
11 periampullary adenoma 10.2 HRAS KRAS
12 paronychia 10.2 HRAS KRAS
13 schimmelpenning-feuerstein-mims syndrome 10.2 HRAS KRAS
14 bile duct cysts 10.2 HRAS KRAS
15 aggressive digital papillary adenocarcinoma 10.2 HRAS KRAS
16 lung adenoid cystic carcinoma 10.2 HRAS KRAS
17 nasal cavity adenocarcinoma 10.2 HRAS KRAS
18 secondary hypertrophic osteoarthropathy 10.2 HRAS KRAS
19 anal canal adenocarcinoma 10.2 HRAS KRAS
20 biliary papillomatosis 10.1 HRAS KRAS
21 acneiform dermatitis 10.1 HRAS KRAS
22 colloid carcinoma of the pancreas 10.1 HRAS KRAS
23 core binding factor acute myeloid leukemia 10.1 HRAS KRAS
24 biliary tract neoplasm 10.1 HRAS KRAS
25 mucinous lung adenocarcinoma 10.1 HRAS KRAS
26 duodenum cancer 10.1 HRAS KRAS
27 liver angiosarcoma 10.1 HRAS KRAS
28 villous adenoma 10.1 GNAS KRAS
29 malignant ovarian surface epithelial-stromal neoplasm 10.1 HRAS KRAS ZNF217
30 ovary epithelial cancer 10.1 HRAS KRAS ZNF217
31 cecum adenocarcinoma 10.1 HRAS KRAS
32 zollinger-ellison syndrome 10.1
33 adenocarcinoma 10.1
34 adenosquamous lung carcinoma 10.1 HRAS KRAS
35 costello syndrome 10.1 HRAS KRAS
36 ampulla of vater cancer 10.0 HRAS KRAS
37 ovarian serous cystadenocarcinoma 10.0 HRAS UBE4A ZNF217
38 myeloma, multiple 10.0 ABCB1 HRAS KRAS
39 appendix disease 10.0 GNAS HRAS KRAS
40 gastrointestinal system benign neoplasm 10.0 HRAS KRAS
41 cell type benign neoplasm 10.0 GNAS HRAS KRAS
42 endocrine gland cancer 10.0 GNAS HRAS KRAS
43 ovary adenocarcinoma 10.0 ARL11 HRAS KRAS ZNF217
44 pancreas adenocarcinoma 10.0 GNAS HRAS KRAS
45 leukemia, chronic lymphocytic 10.0 ABCB1 ARL11 HRAS KRAS
46 small cell carcinoma 9.9
47 sarcoma 9.9
48 endosalpingiosis 9.9
49 leiomyosarcoma 9.9
50 giant cell tumor 9.9

Graphical network of the top 20 diseases related to Ovarian Cystadenocarcinoma:



Diseases related to Ovarian Cystadenocarcinoma

Symptoms & Phenotypes for Ovarian Cystadenocarcinoma

MGI Mouse Phenotypes related to Ovarian Cystadenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.1 ABCB1 CLEC4C GNAS HRAS KRAS LMX1A

Drugs & Therapeutics for Ovarian Cystadenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Non Ivasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis Unknown status NCT02130648
2 MRI Perfusion in Adnexal Masses Completed NCT02694406

Search NIH Clinical Center for Ovarian Cystadenocarcinoma

Genetic Tests for Ovarian Cystadenocarcinoma

Anatomical Context for Ovarian Cystadenocarcinoma

MalaCards organs/tissues related to Ovarian Cystadenocarcinoma:

41
Ovary, Liver, Appendix, Lung, Pancreas, Myeloid, Small Intestine

Publications for Ovarian Cystadenocarcinoma

Articles related to Ovarian Cystadenocarcinoma:

(show all 43)
# Title Authors Year
1
Pathology in Practice. Concurrent metastatic mammary adenocarcinoma and ovarian cystadenocarcinoma in a jaguar. ( 26517614 )
2015
2
Spontaneous rupture of ovarian cystadenocarcinoma: pre- and post-rupture computed tomography evaluation. ( 26543286 )
2015
3
Mediastinal recurrence from ovarian cystadenocarcinoma presenting as pleuro-pericardial cyst. ( 25070811 )
2014
4
Serous ovarian cystadenocarcinoma incidentally discovered in a 29-year-old patient: case report. ( 21077487 )
2010
5
Ovarian cystadenocarcinoma and pseudomyxoma peritonei. ( 22753161 )
2010
6
Peritoneal implantations of papillary serous ovarian cystadenocarcinoma 13 days after initial laparoscopic treatment for a presumed benign ovarian cyst. ( 19317271 )
2009
7
[Expression of ZNF217 in human ovarian cystadenocarcinoma and its clinical significance]. ( 19403395 )
2009
8
Clinical challenges and images in GI. Gastric metastases of an ovarian cystadenocarcinoma with psammoma bodies. ( 18166345 )
2008
9
Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells. ( 17439664 )
2007
10
Papillary ovarian cystadenocarcinoma in a dog. ( 15900901 )
2005
11
Calcified "Sister Mary Joseph" umbilical metastasis from ovarian cystadenocarcinoma seen on an MDP bone scintigram. ( 11786748 )
2002
12
DNA replication errors are frequent in mucinous cystadenocarcinoma of the ovary. ( 10700869 )
2000
13
Transplantation of a human ovarian cystadenocarcinoma into severe combined immunodeficient (SCID) mice--formation of metastases without significant alteration of the tumour cell phenotype. ( 8977374 )
1996
14
Ectopic fallopian tube and ovarian cystadenocarcinoma in an inguinal hernia. ( 7888473 )
1994
15
Liver metastases from ovarian cystadenocarcinoma masquerading on CT as lobar fatty infiltration. ( 8370842 )
1993
16
Tumor DNA ploidy and prognosis of patients with serous cystadenocarcinoma of the ovary. ( 8334634 )
1993
17
Transition from benign to malignant epithelium in mucinous and serous ovarian cystadenocarcinoma. ( 1427402 )
1992
18
Sigmoid colon fistula complicating ovarian cystadenocarcinoma: a rare finding. ( 2298359 )
1990
19
Metastatic ovarian cystadenocarcinoma in a gilt. ( 2076079 )
1990
20
A case of ovarian cystadenocarcinoma associated with pregnancy. ( 2196390 )
1990
21
Zollinger-Ellison syndrome due to gastrin-secreting ovarian cystadenocarcinoma. Case report. ( 2349859 )
1990
22
Gastrin-producing ovarian cystadenocarcinoma: sensitivity to secretin and SMS 201-995. ( 2473000 )
1989
23
A serious ovarian cystadenocarcinoma metastatic to both eyes. ( 3618146 )
1987
24
Mucinous adenocarcinoma of the appendix presenting as an ovarian cystadenocarcinoma: case report and review of appendiceal neoplasms with ovarian metastases. ( 3023143 )
1986
25
Tumour-associated antigens for cystadenocarcinoma of the ovary. ( 6413113 )
1983
26
Ovarian cystadenocarcinoma in a 4-year-old girl: report of a case and review of the literature. ( 7076039 )
1982
27
Zollinger-Ellison syndrome due to a gastrin-producing ovarian cystadenocarcinoma. ( 7296246 )
1981
28
Cystadenocarcinoma of the ovary in a 4-year-old: benign transformation during therapy. ( 7370965 )
1980
29
Characterization of the carcinoembryonic antigen activity associated with cyst fluids of mucinous ovarian cystadenocarcinoma. ( 85489 )
1979
30
The treatment of advanced cystadenocarcinoma of the ovary with gestronol and continuous oral cyclophosphamide. ( 476014 )
1979
31
Kinetics of growth and ectopic production of human chorionic gonadotropin by an ovarian cystadenocarcinoma cell line maintained in vitro. ( 626979 )
1978
32
Bullous pemphigoid and ovarian cystadenocarcinoma. Immunologic studies. ( 78684 )
1978
33
Amylase-containing ovarian cystadenocarcinoma simulating a pancreatic pseudocyst. ( 984118 )
1976
34
Grey-scale ultrasound imaging: diagnosis of metastatic secreting cystadenocarcinoma of the ovary. ( 1218309 )
1975
35
Pseudomucinous cystadenocarcinoma of the ovary associated with pregnancy. Case report. ( 4287735 )
1966
36
Calcification in metastatic cystadenocarcinoma of the ovary. ( 13894810 )
1962
37
Coexistent unilateral Krukenberg tumor and pseudomucinous cystadenocarcinoma of the ovary. ( 14451192 )
1962
38
Diagnosis of cystadenocarcinoma of the ovary. ( 13724048 )
1961
39
Pseudomucinous cystadenocarcinoma of the ovary in a 19-year-old patient; a case report. ( 13411085 )
1957
40
Primary ovarian cystadenocarcinoma: solitary metastasis to contralateral inguinal lymph node. ( 13058000 )
1953
41
Pseudomucinous cystadenocarcinoma of the ovary. ( 12996607 )
1952
42
Coincidental pseudomucinous cystadenocarcinoma of the ovary and adenocarcinoma of the rectosigmoid colon; report of a case. ( 18141863 )
1949
43
Pseudomucinous cystadenocarcinoma of the ovary; case report. ( 20296395 )
1947

Variations for Ovarian Cystadenocarcinoma

Expression for Ovarian Cystadenocarcinoma

Search GEO for disease gene expression data for Ovarian Cystadenocarcinoma.

Pathways for Ovarian Cystadenocarcinoma

Pathways related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.89 CLEC4C HRAS KRAS
2
Show member pathways
11.85 GNAS HRAS KRAS
3
Show member pathways
11.72 GNAS HRAS KRAS
4 11.49 GNAS HRAS KRAS
5 11.08 HRAS KRAS
6 11.08 GNAS HRAS KRAS
7 11.01 HRAS KRAS
8 11 HRAS KRAS
9
Show member pathways
10.97 HRAS KRAS
10
Show member pathways
10.91 HRAS KRAS
11 10.79 HRAS KRAS
12 10.75 HRAS KRAS
13 10.62 HRAS KRAS
14 10.58 GNAS HRAS KRAS
15 10.27 HRAS KRAS

GO Terms for Ovarian Cystadenocarcinoma

Biological processes related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of long-term neuronal synaptic plasticity GO:0048169 9.16 HRAS KRAS
2 response to isolation stress GO:0035900 8.96 HRAS KRAS
3 stimulatory C-type lectin receptor signaling pathway GO:0002223 8.8 CLEC4C HRAS KRAS

Molecular functions related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 GTP binding GO:0005525 8.92 ARL11 GNAS HRAS KRAS

Sources for Ovarian Cystadenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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