MCID: OVR047
MIFTS: 38

Ovarian Cystadenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystadenocarcinoma

MalaCards integrated aliases for Ovarian Cystadenocarcinoma:

Name: Ovarian Cystadenocarcinoma 12 15 17 70
Cystadenocarcinoma of the Ovary 12
Cystadenocarcinoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3605
NCIt 50 C5228
SNOMED-CT 67 314191009
UMLS 70 C1096638

Summaries for Ovarian Cystadenocarcinoma

Disease Ontology : 12 An ovary adenocarcinoma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary : Ovarian Cystadenocarcinoma, also known as cystadenocarcinoma of the ovary, is related to ovarian mucinous cystadenocarcinoma and cystadenocarcinoma. An important gene associated with Ovarian Cystadenocarcinoma is ZNF217 (Zinc Finger Protein 217), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and PI3K-Akt signaling pathway. Affiliated tissues include ovary, breast and lung, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Ovarian Cystadenocarcinoma

Diseases related to Ovarian Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 369)
# Related Disease Score Top Affiliating Genes
1 ovarian mucinous cystadenocarcinoma 32.2 SERPINA3 CEACAM5
2 cystadenocarcinoma 30.9 ZNF217 TP53 SERPINA3 PIK3CA MUC1 MIR30A
3 urachal adenocarcinoma 30.7 KRAS GNAS CEACAM5
4 mucinous cystadenocarcinoma 30.7 SERPINA3 MUC1 CEACAM5
5 cervical adenocarcinoma 30.5 TP53 KRAS CEACAM5
6 appendix adenocarcinoma 30.5 KRAS HRAS GNAS
7 cystadenoma 30.5 SERPINA3 MUC6 MUC1 GNAS CEACAM5 BRCA1
8 small cell carcinoma 30.4 TP53 MUC1 KRAS BRCA2
9 cholecystitis 30.4 TP53 MUC6 MUC1
10 mucinous adenocarcinoma 30.3 TP53 MUC1 KRAS CEACAM5
11 breast adenocarcinoma 30.2 TP53 SERPINA3 PIK3CA KRAS ABCB1
12 serous cystadenocarcinoma 30.2 ZNF217 TP53 PIK3CA MIR30A KRAS HRAS
13 squamous cell carcinoma 30.2 TP53 PIK3CA MUC1 HRAS GNAS CEACAM5
14 papillary adenocarcinoma 30.2 TP53 MUC1 MIR30A KRAS CEACAM5 BRCA2
15 pseudomyxoma peritonei 30.1 TP53 MUC6 MUC1 KRAS GNAS CEACAM5
16 rectum adenocarcinoma 30.1 TP53 SLC25A16 PIK3CA KRAS HRAS CEACAM5
17 endocervical adenocarcinoma 30.0 TP53 SLC25A16 PIK3CA MUC6 MUC1 CEACAM5
18 appendix cancer 30.0 TP53 MUC6 MUC1 KRAS HRAS GNAS
19 ovarian cancer 30.0 TP53 PIK3CA MUC1 MIR30A MIR17 KRAS
20 ovarian serous cystadenocarcinoma 30.0 ZNF217 TP53 SERPINA3 PIK3CA MIR744 MIR30A
21 endometrial cancer 29.8 TP53 SERPINA3 PIK3CA MUC1 KRAS HRAS
22 ovary adenocarcinoma 28.9 TP53 SERPINA3 RNF43 PIK3CA MUC1 MIR744
23 ovarian clear cell cystadenocarcinoma 11.1
24 hepatic flexure cancer 10.5 KRAS HRAS
25 mucoepidermoid esophageal carcinoma 10.5 TP53 CEACAM5
26 pancreatic cystadenocarcinoma 10.5 KRAS CEACAM5
27 trachea carcinoma in situ 10.5 KRAS HRAS
28 cobblestone retinal degeneration 10.5 KRAS HRAS
29 ovarian mucinous adenocarcinoma 10.5 SERPINA3 CEACAM5 ABCB1
30 adult teratoma 10.5 TP53 CEACAM5
31 undifferentiated embryonal sarcoma of the liver 10.5 TP53 SERPINA3
32 fallopian tube clear cell adenocarcinoma 10.5 BRCA2 BRCA1
33 ampulla of vater benign neoplasm 10.5 KRAS HRAS
34 rectosigmoid junction neoplasm 10.5 KRAS CEACAM5
35 sigmoid neoplasm 10.5 KRAS CEACAM5
36 intrahepatic biliary papillomatosis 10.5 MUC1 KRAS
37 ovarian clear cell adenofibroma 10.5 PIK3CA KRAS
38 vulvar eccrine porocarcinoma 10.5 MUC1 CEACAM5
39 xanthogranulomatous cholecystitis 10.5 TP53 SERPINA3 CEACAM5
40 nodular hidradenoma 10.5 MUC1 CEACAM5
41 signet ring basal cell carcinoma 10.5 KRAS HRAS CEACAM5
42 immature teratoma of ovary 10.5 KRAS HRAS CEACAM5
43 pancreatic acinar cell adenocarcinoma 10.5 SERPINA3 KRAS HRAS
44 descending colon cancer 10.4 KRAS HRAS CEACAM5
45 periampullary adenoma 10.4 KRAS HRAS
46 mature teratoma 10.4 TP53 KRAS CEACAM5
47 transverse colon cancer 10.4 KRAS HRAS CEACAM5
48 ovary transitional cell carcinoma 10.4 BRCA2 BRCA1
49 sweat gland benign neoplasm 10.4 TP53 SERPINA3 CEACAM5
50 ascending colon cancer 10.4 KRAS HRAS CEACAM5

Graphical network of the top 20 diseases related to Ovarian Cystadenocarcinoma:



Diseases related to Ovarian Cystadenocarcinoma

Symptoms & Phenotypes for Ovarian Cystadenocarcinoma

GenomeRNAi Phenotypes related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

26 (show all 12)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-1 9.66 HRAS KRAS MUC1 PIK3CA
2 Decreased viability GR00055-A-2 9.66 HRAS KRAS MUC1 PIK3CA
3 Decreased viability GR00055-A-3 9.66 KRAS
4 Decreased viability GR00106-A-0 9.66 KRAS
5 Decreased viability GR00221-A-1 9.66 HRAS KRAS PIK3CA
6 Decreased viability GR00221-A-2 9.66 HRAS KRAS PIK3CA
7 Decreased viability GR00221-A-3 9.66 HRAS
8 Decreased viability GR00221-A-4 9.66 PIK3CA
9 Decreased viability GR00249-S 9.66 MUC1
10 Decreased viability GR00301-A 9.66 KRAS
11 Decreased viability GR00381-A-1 9.66 KRAS
12 Decreased viability GR00402-S-2 9.66 PIK3CA

MGI Mouse Phenotypes related to Ovarian Cystadenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.23 BRCA1 BRCA2 GNAS HRAS KRAS PIK3CA

Drugs & Therapeutics for Ovarian Cystadenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Non-invasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis by Quantitative Real Time MEMO-PCR Unknown status NCT02130648

Search NIH Clinical Center for Ovarian Cystadenocarcinoma

Genetic Tests for Ovarian Cystadenocarcinoma

Anatomical Context for Ovarian Cystadenocarcinoma

MalaCards organs/tissues related to Ovarian Cystadenocarcinoma:

40
Ovary, Breast, Lung, Colon, Thyroid, Appendix, Skin

Publications for Ovarian Cystadenocarcinoma

Articles related to Ovarian Cystadenocarcinoma:

(show top 50) (show all 287)
# Title Authors PMID Year
1
Primary malignant pericardial tumour in Lynch syndrome. 61
32143595 2020
2
Early Onset Immune-Related Adverse Event to Identify Pseudo-Progression in a Patient With Ovarian Cancer Treated With Nivolumab: A Case Report and Review of the Literature. 61
32850889 2020
3
Proceedings of the 2019 National Toxicology Program Satellite Symposium. 61
31645210 2019
4
Giant ovarian cystadenocarcinoma in an adult patient, a rare finding in modern times. 61
31308929 2019
5
[The morphological and molecular genetic characteristics of nephroblastomas in immature ovarian teratoma in adult patients]. 61
31626209 2019
6
The diagnostic challenge of ovarian carcinoma in normal-sized ovaries: a report of two cases. 61
30098285 2018
7
A computational framework for complex disease stratification from multiple large-scale datasets. 61
29843806 2018
8
Mucinous cystadenocarcinoma of the breast: the challenge of diagnosing a rare entity. 61
29081926 2017
9
Mucinous cystadenocarcinoma of ovary with metastasis in 14-year-old girl. 61
28344967 2017
10
False Positive Diagnosis of Hepatocellular Carcinoma in Liver Resection Patients. 61
28049244 2017
11
Cells redox environment modulates BRCA1 expression and DNA homologous recombination repair. 61
27771433 2016
12
Association mining of mutated cancer genes in different clinical stages across 11 cancer types. 61
27556693 2016
13
IL-27 suppresses SKOV3 cells proliferation by enhancing STAT3 and inhibiting the Akt signal pathway. 61
27639718 2016
14
Ovarian carcinoma presenting as cutaneous nasal metastasis. 61
28300910 2016
15
Giant mucinous cystadenocarcinoma of ovary: A case report and review of literature. 61
27134482 2016
16
Pathology in Practice. Concurrent metastatic mammary adenocarcinoma and ovarian cystadenocarcinoma in a jaguar. 61
26517614 2015
17
"Sea anemone-like ciliated tumor cells" in a case of serous cystadenocarcinoma of the ovary. 61
26811576 2015
18
Spontaneous rupture of ovarian cystadenocarcinoma: pre- and post-rupture computed tomography evaluation. 61
26543286 2015
19
Extragenital malignant mixed Mullerian tumor in the incisional hernia - primary carcinosarcoma in the abdominal wall: case report. 61
26012132 2015
20
Krukenberg carcinoma metastasized from stomach resembling mucinous cystadenocarcinoma of the ovary. 61
26259386 2015
21
A weeping umbilical hernia: bilateral ovarian mucinous cystadenoma with disseminated peritoneal adenomucinosis. 61
24855082 2014
22
A 57-year-old Brazilian woman with a giant mucinous cystadenocarcinoma of the ovary: a case report. 61
24594205 2014
23
Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of high-grade histopathologic malignancy. 61
24636424 2014
24
Mediastinal recurrence from ovarian cystadenocarcinoma presenting as pleuro-pericardial cyst. 61
25070811 2014
25
A case of Krukenberg carcinoma metastasized from colon cancer resembling mucinous cystadenocarcinoma of the ovary. 61
24427362 2014
26
Evaluation of clinico: pathologic findings of breast carcinoma in a general hospital in Southern India. 61
24369200 2013
27
Calcitriol-mediated hypercalcemia: causes and course in 101 patients. 61
23979953 2013
28
Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent. 61
23302520 2013
29
Synchronous papillary cystadenocarcinoma of ovary and squamous cell carcinoma of lower vagina: first report of an unusual chance occurrence. 61
23314878 2013
30
A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy. 61
22505474 2012
31
Human telomerase reverse transcriptase expression in ovarian tumors. 61
22771641 2012
32
Involvement of ARLTS1 in chemotherapy and apoptosis in ovarian cancer cell line. 61
21153650 2011
33
Testicular papillary serous cystadenocarcinoma: a rare case report and review of the literature. 61
22355499 2011
34
Hemoperitoneum due to spontaneous rupture of ovarian adenocarcinoma. 61
21221696 2011
35
Consequences of abdominal adenocarcinoma in post-menopausal woman in relation to surgical and non-surgical management. 61
21863621 2011
36
Malignant mixed Mullerian tumor of broad ligament with synchronous ovarian and endometrial carcinoma: a rare association. 61
21546752 2011
37
Peritoneal Malignant Psammomatous Mesothelioma. 61
29147203 2010
38
Ovarian cystadenocarcinoma and pseudomyxoma peritonei. 61
22753161 2010
39
Coexistent intramedullary spinal cord and choroidal metastases in ovarian cancer. 61
20178552 2010
40
Histopathologically proven mucinous cystadenocarcinoma metastatic to the choroid. 61
25390397 2010
41
Serous ovarian cystadenocarcinoma incidentally discovered in a 29-year-old patient: case report. 61
21077487 2010
42
Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy. 61
19205713 2009
43
Improvement of sensitivity to platinum compound with siRNA knockdown of upregulated genes in platinum complex-resistant ovarian cancer cells in vitro. 61
18571892 2009
44
Serous cystadenocarcinoma of the ovary in an 11-year-old girl with extensive dissemination and chylothorax: a case report and a brief review of literature. 61
19564753 2009
45
[Expression of ZNF217 in human ovarian cystadenocarcinoma and its clinical significance]. 61
19403395 2009
46
[Effects of ARLTS1 gene on growth and apoptosis of epithelial ovarian cancer SKOV3 cells]. 61
19292033 2009
47
Peritoneal implantations of papillary serous ovarian cystadenocarcinoma 13 days after initial laparoscopic treatment for a presumed benign ovarian cyst. 61
19317271 2009
48
Adenocarcinoma of the abdominal wall. 61
19122935 2008
49
Clinical challenges and images in GI. Gastric metastases of an ovarian cystadenocarcinoma with psammoma bodies. 61
18166345 2008
50
Small cell carcinoma of pulmonary type inside a microinvasive mucinous cystadenocarcinoma of the ovary: a case report. 61
17885493 2007

Variations for Ovarian Cystadenocarcinoma

Expression for Ovarian Cystadenocarcinoma

Search GEO for disease gene expression data for Ovarian Cystadenocarcinoma.

Pathways for Ovarian Cystadenocarcinoma

Pathways related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

(show all 48)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.25 TP53 SERPINA3 PIK3CA KRAS HRAS GNAS
2
Show member pathways
12.9 TP53 PIK3CA KRAS HRAS GNAS BRCA1
3
Show member pathways
12.76 TP53 PIK3CA KRAS HRAS BRCA2
4 12.66 TP53 PIK3CA KRAS HRAS GNAS BRCA2
5
Show member pathways
12.6 TP53 KRAS HRAS BRCA2 BRCA1
6
Show member pathways
12.42 TP53 PIK3CA KRAS HRAS
7
Show member pathways
12.4 MUC6 MUC1 KRAS HRAS
8
Show member pathways
12.38 PIK3CA KRAS HRAS GNAS
9
Show member pathways
12.37 PIK3CA KRAS HRAS BRCA1
10
Show member pathways
12.37 TP53 PIK3CA KRAS HRAS BRCA2 BRCA1
11
Show member pathways
12.31 TP53 MUC1 KRAS HRAS
12 12.3 TP53 PIK3CA KRAS HRAS
13
Show member pathways
12.29 TP53 PIK3CA HRAS GNAS
14 12.24 TP53 PIK3CA KRAS HRAS
15 12.23 TP53 PIK3CA KRAS HRAS
16
Show member pathways
12.21 PIK3CA MUC1 KRAS HRAS
17
Show member pathways
12.18 PIK3CA KRAS HRAS GNAS
18
Show member pathways
12.14 PIK3CA KRAS HRAS CEACAM5
19
Show member pathways
12.1 TP53 PIK3CA KRAS HRAS GNAS BRCA2
20
Show member pathways
12.08 TP53 PIK3CA KRAS HRAS
21 12.06 TP53 PIK3CA KRAS HRAS
22 12.04 TP53 KRAS BRCA2 BRCA1
23
Show member pathways
12.02 TP53 PIK3CA KRAS HRAS
24
Show member pathways
12 PIK3CA KRAS HRAS GNAS
25 11.95 PIK3CA KRAS HRAS GNAS
26 11.86 TP53 PIK3CA KRAS HRAS
27
Show member pathways
11.83 PIK3CA KRAS HRAS
28 11.82 KRAS HRAS GNAS
29 11.81 TP53 PIK3CA KRAS HRAS
30
Show member pathways
11.78 TP53 BRCA2 BRCA1
31
Show member pathways
11.77 PIK3CA KRAS HRAS
32 11.73 TP53 PIK3CA KRAS HRAS
33 11.72 TP53 PIK3CA MIR30A MIR17 KRAS HRAS
34 11.71 TP53 PIK3CA BRCA1
35 11.71 TP53 KRAS HRAS
36 11.7 PIK3CA KRAS HRAS
37 11.68 PIK3CA KRAS HRAS
38 11.67 PIK3CA KRAS HRAS
39 11.66 TP53 KRAS HRAS
40 11.65 PIK3CA HRAS GNAS
41 11.64 PIK3CA KRAS HRAS
42 11.6 PIK3CA KRAS HRAS
43 11.56 KRAS HRAS GNAS
44 11.47 TP53 PIK3CA KRAS HRAS
45 11.38 TP53 PIK3CA HRAS BRCA1
46 11.25 KRAS HRAS ABCB1
47 11.06 PIK3CA KRAS HRAS
48 10.77 TP53 ABCB1

GO Terms for Ovarian Cystadenocarcinoma

Biological processes related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 liver development GO:0001889 9.65 PIK3CA KRAS HRAS
2 Ras protein signal transduction GO:0007265 9.63 TP53 KRAS HRAS
3 double-strand break repair GO:0006302 9.54 TP53 BRCA2 BRCA1
4 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.46 MUC6 MUC1 KRAS HRAS
5 stem cell proliferation GO:0072089 9.43 RNF43 ABCB1
6 response to isolation stress GO:0035900 9.4 KRAS HRAS
7 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.32 TP53 MUC1
8 chordate embryonic development GO:0043009 9.26 BRCA2 BRCA1
9 cell aging GO:0007569 9.13 TP53 HRAS BRCA2
10 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.92 TP53 MUC1 BRCA2 BRCA1

Sources for Ovarian Cystadenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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