MCID: OVR047
MIFTS: 38

Ovarian Cystadenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
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Aliases & Classifications for Ovarian Cystadenocarcinoma

MalaCards integrated aliases for Ovarian Cystadenocarcinoma:

Name: Ovarian Cystadenocarcinoma 11 14 16 71
Cystadenocarcinoma of the Ovary 11
Cystadenocarcinoma of Ovary 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3605
NCIt 49 C5228
SNOMED-CT 68 314191009
UMLS 71 C1096638

Summaries for Ovarian Cystadenocarcinoma

Disease Ontology: 11 An ovary adenocarcinoma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary: Ovarian Cystadenocarcinoma, also known as cystadenocarcinoma of the ovary, is related to ovarian mucinous cystadenocarcinoma and appendix adenocarcinoma. An important gene associated with Ovarian Cystadenocarcinoma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are DNA IR-double strand breaks and cellular response via ATM and Integrated breast cancer pathway. Affiliated tissues include ovary, lymph node and spinal cord, and related phenotypes are neoplasm and muscle

Related Diseases for Ovarian Cystadenocarcinoma

Diseases related to Ovarian Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 441)
# Related Disease Score Top Affiliating Genes
1 ovarian mucinous cystadenocarcinoma 32.3 SERPINA3 CEACAM5
2 appendix adenocarcinoma 31.6 TP53 KRAS HRAS GNAS CEACAM5
3 cystadenocarcinoma 31.4 TP53 SERPINA3 MIR30A KRAS CEACAM5 BRCA2
4 cystadenoma 30.8 SERPINA3 GNAS CEACAM5 BRCA1
5 ovarian cyst 30.8 GNAS CEACAM5 BRCA1
6 ovarian cystadenoma 30.7 TP53 CEACAM5 BRCA1
7 mucinous cystadenocarcinoma 30.7 SERPINA3 KRAS HRAS CEACAM5
8 bladder urachal carcinoma 30.7 KRAS HRAS
9 serous cystadenocarcinoma 30.6 TP53 MIR30A KRAS HRAS BRCA2 BRCA1
10 adenocarcinoma 30.6 TP53 KRAS HRAS CEACAM5 BRCA2
11 cervical adenocarcinoma 30.6 TP53 KRAS CEACAM5
12 ovarian cancer 30.5 TP53 MIR30A MIR196A1 MIR17 KRAS ICOSLG
13 colonic benign neoplasm 30.5 TP53 SERPINA3 RNF43 KRAS HRAS CEACAM5
14 papillary adenocarcinoma 30.5 TP53 MIR30A KRAS HRAS CEACAM5 BRCA1
15 appendiceal neoplasm 30.5 KRAS HRAS GNAS CEACAM5
16 pseudomyxoma peritonei 30.5 TP53 KRAS GNAS CEACAM5
17 mucinous adenocarcinoma 30.3 U2AF1 TP53 KRAS HRAS GNAS CEACAM5
18 rectum adenocarcinoma 30.3 U2AF1 TP53 SLC25A16 KRAS HRAS CEACAM5
19 endocervical adenocarcinoma 30.3 U2AF1 TP53 SLC25A16 ICOSLG HRAS CEACAM5
20 endometrial cancer 30.2 TP53 MIR30A KRAS HRAS CEACAM5 BRCA2
21 breast adenocarcinoma 30.1 U2AF1 TP53 SERPINA3 KRAS HRAS CEACAM5
22 leiomyosarcoma 30.1 TP53 SERPINA3 BRCA1
23 breast cancer 29.8 TP53 SERPINA3 MIR30A MIR22 MIR196A1 MIR17
24 ovarian serous cystadenocarcinoma 29.6 U2AF1 TP53 SLC25A16 SERPINA3 RNF43 MIR744
25 colorectal cancer 29.6 U2AF1 TP53 SERPINA3 RNF43 MIR483 MIR30A
26 ovary adenocarcinoma 29.1 U2AF1 TP53 SLC25A16 SERPINA3 RNF43 MIR744
27 ovarian clear cell cystadenocarcinoma 11.1
28 mucoepidermoid esophageal carcinoma 10.5 TP53 CEACAM5
29 signet ring basal cell carcinoma 10.5 KRAS CEACAM5
30 blastoma 10.5 TP53 KRAS HRAS
31 carcinosarcoma 10.5 TP53 KRAS HRAS
32 immature teratoma of ovary 10.5 KRAS CEACAM5
33 trachea carcinoma in situ 10.5 KRAS HRAS
34 endometrial mucinous adenocarcinoma 10.5 KRAS GNAS
35 pancreatic foamy gland adenocarcinoma 10.5 TP53 CEACAM5
36 apocrine adenocarcinoma 10.5 TP53 SERPINA3 CEACAM5
37 cholangitis 10.5 TP53 MIR483 CEACAM5
38 syringocystadenoma papilliferum 10.5 SERPINA3 HRAS CEACAM5
39 vaginal carcinosarcoma 10.5 TP53 KRAS HRAS
40 hepatic flexure cancer 10.5 KRAS HRAS CEACAM5
41 descending colon cancer 10.5 KRAS HRAS CEACAM5
42 common bile duct neoplasm 10.5 KRAS HRAS GNAS
43 mucinous intrahepatic cholangiocarcinoma 10.5 KRAS HRAS CEACAM5
44 sigmoid neoplasm 10.5 KRAS HRAS CEACAM5
45 liver angiosarcoma 10.5 TP53 KRAS HRAS
46 malignant spindle cell melanoma 10.5 TP53 SERPINA3 HRAS
47 transverse colon cancer 10.5 KRAS HRAS CEACAM5
48 cystadenofibroma 10.5 TP53 KRAS HRAS
49 malignant spiradenoma 10.5 TP53 CEACAM5
50 ascending colon cancer 10.5 KRAS HRAS CEACAM5

Graphical network of the top 20 diseases related to Ovarian Cystadenocarcinoma:



Diseases related to Ovarian Cystadenocarcinoma

Symptoms & Phenotypes for Ovarian Cystadenocarcinoma

MGI Mouse Phenotypes related to Ovarian Cystadenocarcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.96 BRCA1 BRCA2 CEACAM5 ERCC6 GNAS HRAS
2 muscle MP:0005369 9.76 BRCA1 CEACAM5 ERCC6 GNAS HRAS KRAS
3 digestive/alimentary MP:0005381 9.56 BRCA1 BRCA2 CEACAM5 GNAS HRAS KRAS
4 integument MP:0010771 9.28 BRCA1 BRCA2 ERCC6 GNAS HRAS KRAS

Drugs & Therapeutics for Ovarian Cystadenocarcinoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Non-invasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis by Quantitative Real Time MEMO-PCR Unknown status NCT02130648

Search NIH Clinical Center for Ovarian Cystadenocarcinoma

Genetic Tests for Ovarian Cystadenocarcinoma

Anatomical Context for Ovarian Cystadenocarcinoma

Organs/tissues related to Ovarian Cystadenocarcinoma:

MalaCards : Ovary, Lymph Node, Spinal Cord, Appendix, Breast, Small Intestine, Cervix

Publications for Ovarian Cystadenocarcinoma

Articles related to Ovarian Cystadenocarcinoma:

(show top 50) (show all 307)
# Title Authors PMID Year
1
A Rare Case of Low-Grade Serous Cystadenocarcinoma of the Ovary in a Seventeen-Year-Old Woman. 62
36128000 2022
2
Giant Mucinous Cystadenocarcinoma of the Ovary with Cavitary Metastases to Lungs in a Postmenopausal Woman: A Rare Presentation. 62
35746916 2022
3
Choroidal mass secondary to mucinous cystadenocarcinoma of ovary in a young woman: a life-threatening metastasis. 62
34179588 2021
4
A Fatal and Rare Case of Hydatid Cyst in the Pouch of Douglas. 62
34149232 2021
5
Primary malignant pericardial tumour in Lynch syndrome. 62
32143595 2020
6
Incidental detection of microfilaria in cyst fluid of Mucinous cystadenocarcinoma of ovary: A rare case report. 62
32416487 2020
7
Early Onset Immune-Related Adverse Event to Identify Pseudo-Progression in a Patient With Ovarian Cancer Treated With Nivolumab: A Case Report and Review of the Literature. 62
32850889 2020
8
Proceedings of the 2019 National Toxicology Program Satellite Symposium. 62
31645210 2019
9
Giant ovarian cystadenocarcinoma in an adult patient, a rare finding in modern times. 62
31308929 2019
10
[The morphological and molecular genetic characteristics of nephroblastomas in immature ovarian teratoma in adult patients]. 62
31626209 2019
11
The diagnostic challenge of ovarian carcinoma in normal-sized ovaries: a report of two cases. 62
30098285 2018
12
[Mucinous cystadenocarcinoma of ovary associated with neuroendocrine carcinoma (Primary ovarian pulmonary-type small cell carcinoma): report of a case]. 62
29783809 2018
13
A computational framework for complex disease stratification from multiple large-scale datasets. 62
29843806 2018
14
Mucinous cystadenocarcinoma of the breast: the challenge of diagnosing a rare entity. 62
29081926 2017
15
Mucinous cystadenocarcinoma of ovary with metastasis in 14-year-old girl. 62
28344967 2017
16
False Positive Diagnosis of Hepatocellular Carcinoma in Liver Resection Patients. 62
28049244 2017
17
Cells redox environment modulates BRCA1 expression and DNA homologous recombination repair. 62
27771433 2016
18
IL-27 suppresses SKOV3 cells proliferation by enhancing STAT3 and inhibiting the Akt signal pathway. 62
27639718 2016
19
Association mining of mutated cancer genes in different clinical stages across 11 cancer types. 62
27556693 2016
20
Ovarian carcinoma presenting as cutaneous nasal metastasis. 62
28300910 2016
21
Giant mucinous cystadenocarcinoma of ovary: A case report and review of literature. 62
27134482 2016
22
Pathology in Practice. Concurrent metastatic mammary adenocarcinoma and ovarian cystadenocarcinoma in a jaguar. 62
26517614 2015
23
"Sea anemone-like ciliated tumor cells" in a case of serous cystadenocarcinoma of the ovary. 62
26811576 2015
24
Spontaneous rupture of ovarian cystadenocarcinoma: pre- and post-rupture computed tomography evaluation. 62
26543286 2015
25
Extragenital malignant mixed Mullerian tumor in the incisional hernia - primary carcinosarcoma in the abdominal wall: case report. 62
26012132 2015
26
Krukenberg carcinoma metastasized from stomach resembling mucinous cystadenocarcinoma of the ovary. 62
26259386 2015
27
A weeping umbilical hernia: bilateral ovarian mucinous cystadenoma with disseminated peritoneal adenomucinosis. 62
24855082 2014
28
A 57-year-old Brazilian woman with a giant mucinous cystadenocarcinoma of the ovary: a case report. 62
24594205 2014
29
Metastatic ovarian papillary cystadenocarcinoma to the small intestine serous surface: report of a case of high-grade histopathologic malignancy. 62
24636424 2014
30
Mediastinal recurrence from ovarian cystadenocarcinoma presenting as pleuro-pericardial cyst. 62
25070811 2014
31
A case of Krukenberg carcinoma metastasized from colon cancer resembling mucinous cystadenocarcinoma of the ovary. 62
24427362 2014
32
Evaluation of clinico: pathologic findings of breast carcinoma in a general hospital in Southern India. 62
24369200 2013
33
Calcitriol-mediated hypercalcemia: causes and course in 101 patients. 62
23979953 2013
34
Contribution of the PALB2 c.2323C>T [p.Q775X] founder mutation in well-defined breast and/or ovarian cancer families and unselected ovarian cancer cases of French Canadian descent. 62
23302520 2013
35
Synchronous papillary cystadenocarcinoma of ovary and squamous cell carcinoma of lower vagina: first report of an unusual chance occurrence. 62
23314878 2013
36
IL-17A is elevated in sera of patients with poorly differentiated ovarian papillary serous cystadenocarcinoma. 62
24595078 2013
37
A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy. 62
22505474 2012
38
Human telomerase reverse transcriptase expression in ovarian tumors. 62
22771641 2012
39
Papillary cystadenocarcinoma of ovary presenting as obstructive jaundice: a rare presentation. 62
22496943 2012
40
Involvement of ARLTS1 in chemotherapy and apoptosis in ovarian cancer cell line. 62
21153650 2011
41
Testicular papillary serous cystadenocarcinoma: a rare case report and review of the literature. 62
22355499 2011
42
Hemoperitoneum due to spontaneous rupture of ovarian adenocarcinoma. 62
21221696 2011
43
Consequences of abdominal adenocarcinoma in post-menopausal woman in relation to surgical and non-surgical management. 62
21863621 2011
44
Malignant mixed Mullerian tumor of broad ligament with synchronous ovarian and endometrial carcinoma: a rare association. 62
21546752 2011
45
Peritoneal Malignant Psammomatous Mesothelioma. 62
29147203 2010
46
Ovarian cystadenocarcinoma and pseudomyxoma peritonei. 62
22753161 2010
47
Coexistent intramedullary spinal cord and choroidal metastases in ovarian cancer. 62
20178552 2010
48
Histopathologically proven mucinous cystadenocarcinoma metastatic to the choroid. 62
25390397 2010
49
Serous ovarian cystadenocarcinoma incidentally discovered in a 29-year-old patient: case report. 62
21077487 2010
50
Combined chemotherapy with paclitaxel and carboplatin for mucinous cystadenocarcinoma of the ovary during pregnancy. 62
19205713 2009

Variations for Ovarian Cystadenocarcinoma

Expression for Ovarian Cystadenocarcinoma

Search GEO for disease gene expression data for Ovarian Cystadenocarcinoma.

Pathways for Ovarian Cystadenocarcinoma

GO Terms for Ovarian Cystadenocarcinoma

Cellular components related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RISC complex GO:0016442 9.73 MIR744 MIR30A MIR22 MIR196A1 MIR17 MIR101-1
2 nuclear ubiquitin ligase complex GO:0000152 9.46 BRCA2 BRCA1
3 extracellular vesicle GO:1903561 8.92 MIR30A MIR22 MIR17 MIR101-1

Biological processes related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 miRNA-mediated gene silencing GO:0035195 9.93 MIR101-1 MIR17 MIR196A1 MIR22 MIR30A MIR483
2 cellular response to ionizing radiation GO:0071479 9.85 TP53 BRCA2 BRCA1
3 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.83 ERCC6 BRCA2 BRCA1
4 response to gamma radiation GO:0010332 9.73 TP53 ERCC6 BRCA2
5 positive regulation of gene expression GO:0010628 9.65 TP53 MIR17 MIR101-1 KRAS HRAS ERCC6
6 chordate embryonic development GO:0043009 9.58 BRCA2 BRCA1
7 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.5 MIR483 MIR22 MIR196A1
8 response to X-ray GO:0010165 9.1 TP53 ERCC6 BRCA2

Molecular functions related to Ovarian Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.43 TP53 MIR483 MIR30A MIR17 MIR101-1
2 mRNA base-pairing translational repressor activity GO:1903231 9.1 MIR483 MIR30A MIR22 MIR196A1 MIR17 MIR101-1

Sources for Ovarian Cystadenocarcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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