MCID: OVR048
MIFTS: 34

Ovarian Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystadenoma

MalaCards integrated aliases for Ovarian Cystadenoma:

Name: Ovarian Cystadenoma 12 55 15 73
Simple Cystoma of the Ovary 12
Cystoma Serosum Simplex 12
Simple Cystoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3269
NCIt 50 C4060
UMLS 73 C0346169

Summaries for Ovarian Cystadenoma

Disease Ontology : 12 An ovarian benign neoplasm that has material basis in glandular epithelial tissue in which cystic accumulations of retained secretions are formed.

MalaCards based summary : Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to mucinous ovarian cystadenoma and ovarian papillary cystadenoma. An important gene associated with Ovarian Cystadenoma is BRCA1 (BRCA1, DNA Repair Associated), and among its related pathways/superpathways are Validated targets of C-MYC transcriptional repression and ATF-2 transcription factor network. The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include ovary and bone, and related phenotypes are Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation and cardiovascular system

Wikipedia : 76 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and... more...

Related Diseases for Ovarian Cystadenoma

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to Ovarian Cystadenoma

Symptoms & Phenotypes for Ovarian Cystadenoma

GenomeRNAi Phenotypes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation GR00016-A 8.8 BRCA1 FH LMNA

MGI Mouse Phenotypes related to Ovarian Cystadenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.65 BRCA1 CLU LMNA SELE ZMPSTE24
2 homeostasis/metabolism MP:0005376 9.63 BRCA1 CLU FH LMNA SELE ZMPSTE24
3 muscle MP:0005369 9.26 BRCA1 CLU LMNA ZMPSTE24
4 renal/urinary system MP:0005367 9.02 BRCA1 CLU FH LMNA ZMPSTE24

Drugs & Therapeutics for Ovarian Cystadenoma

Drugs for Ovarian Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved 33069-62-4 36314
2 Albumin-Bound Paclitaxel

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ovarian Clear Cell Adenocarcinoma Review Completed NCT02129036

Search NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

Anatomical Context for Ovarian Cystadenoma

MalaCards organs/tissues related to Ovarian Cystadenoma:

41
Ovary, Bone

Publications for Ovarian Cystadenoma

Articles related to Ovarian Cystadenoma:

(show all 32)
# Title Authors Year
1
Ruptured benign serous ovarian cystadenoma mimicking ovarian malignancy with peritoneal carcinomatosis. ( 27421673 )
2016
2
An unexpected death due to massive ascites and a giant mucinous ovarian cystadenoma. ( 27890095 )
2016
3
Ovarian Cystadenoma in a Trafficked Patient. ( 27244785 )
2016
4
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. ( 25404834 )
2014
5
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). ( 25000708 )
2014
6
Perioperative management for the removal of a massive ovarian cystadenoma. ( 25612086 )
2013
7
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. ( 21792894 )
2012
8
Abnormal A^A^A^I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. ( 22310273 )
2012
9
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. ( 21921381 )
2011
10
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. ( 24396716 )
2011
11
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. ( 20819672 )
2010
12
Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. ( 17179812 )
2007
13
Rapidly growing bilateral ovarian cystadenoma in a 6-year-old girl: case report and literature review. ( 16472727 )
2006
14
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. ( 15131356 )
2004
15
Tuberculous peritonitis with sonographic features of an ovarian cystadenoma. ( 14510274 )
2003
16
Massive ovarian cystadenoma detected solely on the blood-pool phase of a bone scan. ( 12045453 )
2002
17
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. ( 9563228 )
1998
18
Extremely high levels of CA19-9 and CA125 antigen in benign mucinous ovarian cystadenoma. ( 7508878 )
1994
19
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. ( 1382586 )
1992
20
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). ( 1867577 )
1991
21
"Pseudoascites" secondary to an amylase-producing serous ovarian cystadenoma. A case study. ( 2479672 )
1989
22
Borderline ovarian cystadenoma. Spontaneous rupture and reaccumulation documented by ultrasound. ( 3286886 )
1988
23
Ovarian cystadenoma with stromal cell hyperplasia and postmenopausal virilization: a case report. ( 3169360 )
1988
24
A plasminogen activator from benign ovarian cystadenoma: partial purification and characterization. ( 3961743 )
1986
25
Cystic parametrial fibroids mimicking ovarian cystadenoma. ( 6726872 )
1984
26
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. ( 7365959 )
1980
27
A benign serous ovarian cystadenoma studied by chromosome and quantitative DNA analysis. ( 274883 )
1977
28
Virilization in pregnancy associated with an ovarian cystadenoma. ( 4416869 )
1974
29
Acute abdominal symptoms due to torsion of an ovarian cystadenoma in a centenarian. ( 5053461 )
1972
30
Chromosomal aberrations in an ovarian cystadenoma. ( 4185609 )
1969
31
Free and conjugated estrogens of an ovarian cystadenoma and granulosa cell tumor. ( 4284085 )
1965
32
PSEUDOMYXOMA PERITONAEI SECONDARY TO OVARIAN CYSTADENOMA. ( 20317773 )
1930

Variations for Ovarian Cystadenoma

Expression for Ovarian Cystadenoma

Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for Ovarian Cystadenoma

Pathways related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.74 BRCA1 CLU
2 10.36 BRCA1 SELE

GO Terms for Ovarian Cystadenoma

Biological processes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus organization GO:0006997 9.32 LMNA ZMPSTE24
2 negative regulation of release of cytochrome c from mitochondria GO:0090201 9.26 CLU LMNA
3 nuclear envelope organization GO:0006998 9.16 LMNA ZMPSTE24
4 regulation of DNA methylation GO:0044030 8.96 BRCA1 ZMPSTE24
5 positive regulation of gene expression GO:0010628 8.92 BRCA1 CLU LMNA ZMPSTE24

Sources for Ovarian Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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