MCID: OVR048
MIFTS: 32

Ovarian Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
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Aliases & Classifications for Ovarian Cystadenoma

MalaCards integrated aliases for Ovarian Cystadenoma:

Name: Ovarian Cystadenoma 11 53 14 71 75
Simple Cystoma of the Ovary 11
Cystoma Serosum Simplex 11
Simple Cystoma of Ovary 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3269
NCIt 49 C4060
SNOMED-CT 68 198297004
UMLS 71 C0346169

Summaries for Ovarian Cystadenoma

Disease Ontology: 11 An ovarian benign neoplasm that has material basis in glandular epithelial tissue in which cystic accumulations of retained secretions are formed.

MalaCards based summary: Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to mucinous ovarian cystadenoma and cystadenoma. An important gene associated with Ovarian Cystadenoma is CLDN4 (Claudin 4), and among its related pathways/superpathways are Malignant pleural mesothelioma and miRNA regulation of DNA damage response. Affiliated tissues include ovary, uterus and cervix, and related phenotype is homeostasis/metabolism.

Wikipedia: 75 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and... more...

Related Diseases for Ovarian Cystadenoma

Diseases related to Ovarian Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 339)
# Related Disease Score Top Affiliating Genes
1 mucinous ovarian cystadenoma 32.2 WFDC2 KRT7 CEACAM5 AFP
2 cystadenoma 30.9 MUC16 KRT7 CEACAM5 BRCA1 AFP
3 ovarian serous cystadenocarcinoma 30.3 TP53 MUC16 CEACAM5 BRCA1
4 dermoid cyst of ovary 30.2 CEACAM5 AFP
5 tuberculous peritonitis 30.1 MUC16 CEACAM5 AFP
6 appendix adenocarcinoma 30.1 TP53 KRT7 CEACAM5
7 ovarian cyst 30.0 WFDC2 MUC16 CEACAM5 BRCA1 AFP
8 ovarian cystadenocarcinoma 29.7 TP53 MUC16 CEACAM5 BRCA1
9 pseudomyxoma peritonei 29.7 TP53 MUC16 KRT7 CEACAM5
10 benign teratoma 29.6 TP53 KRT7 CEACAM5 AFP
11 cystadenocarcinoma 29.5 TP53 MUC16 KRT7 CEACAM5 BRCA1 AREG
12 cowden syndrome 29.5 TP53 CHEK2 BRCA1
13 ovarian cancer 27.9 WFDC2 TP53 MUC16 KRT7 CLU CLDN4
14 ovarian papillary cystadenoma 11.1
15 ovarian endometrioid cystadenoma 11.1
16 lymphohistiocytoid mesothelioma 10.3 CLDN4 CEACAM5
17 squamous blepharitis 10.3 SELE AREG
18 corpus luteum cyst 10.3 MUC16 AFP
19 ovarian fetiform teratoma 10.3 CEACAM5 AFP
20 spiradenoma 10.3 KRT7 CEACAM5
21 immature teratoma of ovary 10.3 CEACAM5 AFP
22 parovarian cyst 10.3 CEACAM5 AFP
23 rectum signet ring adenocarcinoma 10.3 CEACAM5 AFP
24 leukoplakia of penis 10.3 KRT7 CEACAM5
25 subserous uterine fibroid 10.3 CEACAM5 AFP
26 liver lymphoma 10.3 CEACAM5 AFP
27 esophagus lymphoma 10.3 CEACAM5 AFP
28 urethral villous adenoma 10.3 KRT7 CEACAM5
29 pancreatic serous cystadenocarcinoma 10.3 KRT7 CEACAM5
30 aggressive digital papillary adenocarcinoma 10.3 KRT7 CEACAM5
31 ureter adenocarcinoma 10.3 KRT7 CEACAM5
32 ovarian brenner tumor 10.3 MUC16 KRT7
33 cutaneous mucoepidermoid carcinoma 10.3 KRT7 CEACAM5
34 malignant epithelial mesothelioma 10.3 KRT7 CEACAM5
35 vaginal tubulovillous adenoma 10.3 KRT7 CEACAM5
36 adenosquamous bile duct carcinoma 10.3 KRT7 CEACAM5
37 ovarian mixed germ cell neoplasm 10.3 CEACAM5 AFP
38 ureter squamous cell carcinoma 10.3 KRT7 CEACAM5
39 urinary bladder villous adenoma 10.3 KRT7 CEACAM5
40 apocrine adenoma 10.3 KRT7 CEACAM5
41 vulva adenocarcinoma 10.3 KRT7 CEACAM5
42 hepatic tuberculosis 10.3 CEACAM5 AFP
43 vulval paget's disease 10.3 KRT7 CEACAM5
44 liver lipoma 10.3 CEACAM5 AFP
45 aortic malignant tumor 10.3 KRT7 CEACAM5
46 malignant biphasic mesothelioma 10.3 KRT7 CEACAM5
47 adenoid basal cell carcinoma 10.3 KRT7 CEACAM5
48 liver leiomyoma 10.3 CEACAM5 AFP
49 nodular hidradenoma 10.3 KRT7 CEACAM5
50 hidradenoma 10.3 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to Ovarian Cystadenoma

Symptoms & Phenotypes for Ovarian Cystadenoma

MGI Mouse Phenotypes related to Ovarian Cystadenoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.4 AFP AREG BRCA1 CEACAM5 CHEK2 CLDN3

Drugs & Therapeutics for Ovarian Cystadenoma

Search Clinical Trials, NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

Anatomical Context for Ovarian Cystadenoma

Organs/tissues related to Ovarian Cystadenoma:

MalaCards : Ovary, Uterus, Cervix, Skin, Bone

Publications for Ovarian Cystadenoma

Articles related to Ovarian Cystadenoma:

(show top 50) (show all 133)
# Title Authors PMID Year
1
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. 53 62
15131356 2004
2
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. 53 62
12855632 2003
3
Synthesis of a potential tetrasaccharide ligand for E-selectin. 53 62
11909595 2002
4
Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin. 53 62
7507478 1994
5
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. 53 62
1382586 1992
6
Incidental discovery of a giant ovarian cystadenoma. 62
36268316 2022
7
Two-Port Laparoscopic Removal of Large Ovarian Cystadenoma. 62
33631322 2022
8
Identification of novel candidate genes and small molecule drugs in ovarian cancer by bioinformatics strategy. 62
35836518 2022
9
Histopathological discrepancy and variation of surgical management in mucinous ovarian cystadenoma and pseudomyxoma peritonei. 62
35658307 2022
10
[Neonatal bilateral ovarian cystadenoma: Conservative or surgical treatment?] 62
35735305 2022
11
A Giant Ovarian Cystadenoma in A 20-Year-Old Nulliparous Woman: A Case Report. 62
35599793 2022
12
Giant ovarian cystadenoma in association with Cowden syndrome. 62
35971940 2022
13
Postmenopausal virilization secondary to a large ovarian cystadenoma with stromal hyperthecosis. 62
34584697 2021
14
Permanent neurological deficit caused by misdiagnosis of a giant intrapelvic sciatic schwannoma: A case report. 62
34159689 2021
15
Pfannenstiel incision for surgical excision of a huge pelvi-abdominal cystadenoma: a case report. 62
34321988 2021
16
Unplanned adnexectomy for ovarian cystadenoma with undiagnosed autoamputation of the contralateral ovary, lessons learned from medical mistakes. 62
34184850 2021
17
Intra-splenic ovarian cystadenoma. 62
33927854 2021
18
Determining the significance of psammoma bodies in pelvic washings: A 10-year retrospective review. 62
32931128 2021
19
Expression and Clinical Significance of the NCAPH, AGGF1, and FOXC2 Proteins in Serous Ovarian Cancer. 62
34584452 2021
20
An association of circulating Tregs and Th17 cells producing IL-21 and IL-22 with the ROMA in ovarian cancer patients. 62
32707423 2020
21
Rare Case Report of an Endometrial Adenocarcinoma Arising in a Complete Septate Uterus With a Double Cervix and Vagina. 62
33062503 2020
22
A young woman from an Echinococcus-endemic area with progressive abdominal distension: a case report. 62
32507106 2020
23
A Nomogram Combined Radiomic and Semantic Features as Imaging Biomarker for Classification of Ovarian Cystadenomas. 62
32547958 2020
24
Detection of human cytomegalovirus in patients with epithelial ovarian cancer and its impacts on survival. 62
32322296 2020
25
A Collision between Fibroma and Serous Ovarian Cystadenoma Mimicking Carcinoma. 62
32337883 2019
26
Haemodynamic and respiratory changes following surgical resection of a giant ovarian cystadenoma. 62
31826906 2019
27
A 27-kg Giant Ovarian Mucinous Cystadenoma in a 72-Year-Old Postmenopausal Patient: A Case Report. 62
31672957 2019
28
Preoperative Optimization and Choreographed Physiological Evaluation for Resection of Giant Abdominal Neoplasm: A Case Report. 62
31021824 2019
29
Impact of Human Cytomegalovirus Infection and its Immune Response on Survival of Patients with Ovarian Cancer. 62
30172882 2018
30
Exosomal microRNAs as tumor markers in epithelial ovarian cancer. 62
30107086 2018
31
Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic? 62
29971558 2018
32
Ovarian Adenomatoid Tumor Coexisting with Mature Cystic Teratoma: A Rare Case Report. 62
29085685 2017
33
Ovarian serous cystadenoma with ectopic adrenal tissue in a 65-year-old patient: A case report. 62
28285211 2017
34
An unexpected death due to massive ascites and a giant mucinous ovarian cystadenoma. 62
27890095 2016
35
Ruptured benign serous ovarian cystadenoma mimicking ovarian malignancy with peritoneal carcinomatosis. 62
27421673 2016
36
Ovarian Cystadenoma in a Trafficked Patient. 62
27244785 2016
37
Redundant plantar skin folds. 62
28002528 2016
38
Endometrial stromal nodule - a case report. 62
25725687 2015
39
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. 62
25404834 2014
40
Pseudomixoma peritonei, a rare entity difficult to diagnose and treat - case report. 62
25560512 2014
41
The unique case of foot drop secondary to a large ovarian cyst. 62
24447226 2014
42
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). 62
25000708 2014
43
Perioperative management for the removal of a massive ovarian cystadenoma. 62
25612086 2013
44
Massive Hematometra due to Congenital Cervicovaginal Agenesis in an Adolescent Girl Treated by Hysterectomy: A Case Report. 62
23533866 2013
45
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. 62
21792894 2012
46
AT-rich sequence binding protein 1: Contribution to tumor progression and metastasis of human ovarian carcinoma. 62
22741008 2012
47
Abnormal ¹³¹I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. 62
22310273 2012
48
Reduced CMTM5 expression correlates with carcinogenesis in human epithelial ovarian cancer. 62
21841490 2011
49
FSH inhibits ovarian cancer cell apoptosis by up-regulating survivin and down-regulating PDCD6 and DR5. 62
20943720 2011
50
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. 62
24396716 2011

Variations for Ovarian Cystadenoma

Expression for Ovarian Cystadenoma

Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for Ovarian Cystadenoma

Pathways related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1 12.39 TP53 SELE BRCA1 AREG
2
Show member pathways
11.82 TP53 CHEK2 BRCA1
3
Show member pathways
11.6 TP53 CHEK2 BRCA1
4
Show member pathways
11.5 TP53 CHEK2 BRCA1
5
Show member pathways
11.46 TP53 CHEK2 BRCA1
6 11.41 TP53 CHEK2 BRCA1
7 11.32 TP53 SELE AFP
8 10.78 TP53 CHEK2 BRCA1
9 10.74 TP53 BRCA1
10 10.38 TP53 CHEK2 BRCA1
11 9.93 TP53 CHEK2

GO Terms for Ovarian Cystadenoma

Biological processes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 thymocyte apoptotic process GO:0070242 9.46 TP53 CHEK2
2 double-strand break repair GO:0006302 9.43 TP53 CHEK2 BRCA1
3 positive regulation of metallopeptidase activity GO:1905050 8.92 CLDN4 CLDN3

Sources for Ovarian Cystadenoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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