MCID: OVR048
MIFTS: 30

Ovarian Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystadenoma

MalaCards integrated aliases for Ovarian Cystadenoma:

Name: Ovarian Cystadenoma 12 54 15 70
Simple Cystoma of the Ovary 12
Cystoma Serosum Simplex 12
Simple Cystoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3269
NCIt 50 C4060
SNOMED-CT 67 198297004
UMLS 70 C0346169

Summaries for Ovarian Cystadenoma

Disease Ontology : 12 An ovarian benign neoplasm that has material basis in glandular epithelial tissue in which cystic accumulations of retained secretions are formed.

MalaCards based summary : Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to mucinous ovarian cystadenoma and cystadenoma. An important gene associated with Ovarian Cystadenoma is BRCA1 (BRCA1 DNA Repair Associated), and among its related pathways/superpathways is Cell adhesion molecules. Affiliated tissues include ovary, bone and skin.

Wikipedia : 73 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and... more...

Related Diseases for Ovarian Cystadenoma

Diseases related to Ovarian Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 160)
# Related Disease Score Top Affiliating Genes
1 mucinous ovarian cystadenoma 31.6 KRT7 GAST CEACAM5
2 cystadenoma 30.6 MUC16 KRT7 CEACAM5 BRCA1
3 tuberculous peritonitis 30.1 MUC16 CEACAM5
4 ovarian cystadenocarcinoma 29.6 MUC16 ESS2 CEACAM5 BRCA1
5 cystadenocarcinoma 29.3 MUC16 KRT7 CEACAM5 BRCA1 AREG
6 ovarian papillary cystadenoma 11.1
7 ovarian endometrioid cystadenoma 11.1
8 senile ectropion 10.3 MUC16 LMNA
9 squamous blepharitis 10.3 SELE AREG
10 primary peritoneal carcinoma 10.3 MUC16 BRCA1
11 intracystic papillary adenoma 10.2 CEACAM5 BRCA1
12 endometrial serous adenocarcinoma 10.2 CLDN3 BRCA1
13 serous cystadenocarcinoma 10.1 MUC16 ESS2 BRCA1
14 ovarian serous cystadenocarcinoma 10.1
15 lactase deficiency, congenital 10.1 CLDN4 CLDN3
16 adenofibroma 10.1 MUC16 KRT7
17 ovarian serous adenofibroma 10.0 KRT7 BRCA1
18 ovarian serous cystadenofibroma 10.0 KRT7 BRCA1
19 endosalpingiosis 10.0 KRT7 BRCA1
20 fibroma 10.0
21 cervical adenoma malignum 10.0 KRT7 BRCA1
22 cystadenofibroma 10.0 MUC16 KRT7
23 peritoneal serous adenocarcinoma 10.0 KRT7 CLDN4
24 papillary cystadenocarcinoma 10.0 MUC16 KRT7
25 colon neuroendocrine neoplasm 10.0 GAST CEACAM5
26 corneal dystrophy, posterior polymorphous, 4 9.9 KRT7 CLDN4
27 leukoplakia of penis 9.9 KRT7 CEACAM5
28 gastric fundus cancer 9.9 GAST CEACAM5
29 urethral villous adenoma 9.9 KRT7 CEACAM5
30 ureter adenocarcinoma 9.9 KRT7 CEACAM5
31 mucinous adenofibroma 9.9 KRT7 CEACAM5
32 pancreatic foamy gland adenocarcinoma 9.9 KRT7 CEACAM5
33 malignant acrospiroma 9.9 KRT7 CEACAM5
34 anal paget's disease 9.9 KRT7 CEACAM5
35 pancreatic serous cystadenocarcinoma 9.9 KRT7 CEACAM5
36 urinary bladder villous adenoma 9.9 KRT7 CEACAM5
37 cutaneous mucoepidermoid carcinoma 9.9 KRT7 CEACAM5
38 external ear carcinoma 9.9 KRT7 CEACAM5
39 vulva adenocarcinoma 9.9 KRT7 CEACAM5
40 vulval paget's disease 9.9 KRT7 CEACAM5
41 vaginal tubulovillous adenoma 9.9 KRT7 CEACAM5
42 female urethral cancer 9.9 KRT7 CEACAM5
43 eccrine adenocarcinoma 9.9 KRT7 CEACAM5
44 renal pelvis adenocarcinoma 9.9 KRT7 CEACAM5
45 bile duct cystadenocarcinoma 9.9 KRT7 CEACAM5
46 rectosigmoid junction neoplasm 9.9 KRT7 CEACAM5
47 transverse colon cancer 9.9 KRT7 CEACAM5
48 sigmoid neoplasm 9.9 KRT7 CEACAM5
49 krukenberg carcinoma 9.9 KRT7 CEACAM5
50 vulvar apocrine adenocarcinoma 9.9 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to Ovarian Cystadenoma

Symptoms & Phenotypes for Ovarian Cystadenoma

Drugs & Therapeutics for Ovarian Cystadenoma

Search Clinical Trials , NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

Anatomical Context for Ovarian Cystadenoma

MalaCards organs/tissues related to Ovarian Cystadenoma:

40
Ovary, Bone, Skin, Uterus, Cervix

Publications for Ovarian Cystadenoma

Articles related to Ovarian Cystadenoma:

(show top 50) (show all 121)
# Title Authors PMID Year
1
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. 54 61
15131356 2004
2
Tight junction proteins claudin-3 and claudin-4 are frequently overexpressed in ovarian cancer but not in ovarian cystadenomas. 61 54
12855632 2003
3
Synthesis of a potential tetrasaccharide ligand for E-selectin. 54 61
11909595 2002
4
Sulfated blood group Lewis(a). A superior oligosaccharide ligand for human E-selectin. 54 61
7507478 1994
5
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. 54 61
1382586 1992
6
Two Port Laparoscopic Removal of Large Ovarian Cystadenoma. 61
33631322 2021
7
Determining the significance of psammoma bodies in pelvic washings: A 10-year retrospective review. 61
32931128 2021
8
An association of circulating Tregs and Th17 cells producing IL-21 and IL-22 with the ROMA in ovarian cancer patients. 61
32707423 2020
9
Rare Case Report of an Endometrial Adenocarcinoma Arising in a Complete Septate Uterus With a Double Cervix and Vagina. 61
33062503 2020
10
A young woman from an Echinococcus-endemic area with progressive abdominal distension: a case report. 61
32507106 2020
11
Detection of human cytomegalovirus in patients with epithelial ovarian cancer and its impacts on survival. 61
32322296 2020
12
A Nomogram Combined Radiomic and Semantic Features as Imaging Biomarker for Classification of Ovarian Cystadenomas. 61
32547958 2020
13
A Collision between Fibroma and Serous Ovarian Cystadenoma Mimicking Carcinoma. 61
32337883 2019
14
Haemodynamic and respiratory changes following surgical resection of a giant ovarian cystadenoma. 61
31826906 2019
15
A 27-kg Giant Ovarian Mucinous Cystadenoma in a 72-Year-Old Postmenopausal Patient: A Case Report. 61
31672957 2019
16
Preoperative Optimization and Choreographed Physiological Evaluation for Resection of Giant Abdominal Neoplasm: A Case Report. 61
31021824 2019
17
Impact of Human Cytomegalovirus Infection and its Immune Response on Survival of Patients with Ovarian Cancer. 61
30172882 2018
18
Exosomal microRNAs as tumor markers in epithelial ovarian cancer. 61
30107086 2018
19
Extraparenchymal ovarian and testicular Leydig cells: ectopic/heterotopic or orthotopic? 61
29971558 2018
20
Ovarian serous cystadenoma with ectopic adrenal tissue in a 65-year-old patient: A case report. 61
28285211 2017
21
Ovarian Adenomatoid Tumor Coexisting with Mature Cystic Teratoma: A Rare Case Report. 61
29085685 2017
22
Ruptured benign serous ovarian cystadenoma mimicking ovarian malignancy with peritoneal carcinomatosis. 61
27421673 2016
23
An unexpected death due to massive ascites and a giant mucinous ovarian cystadenoma. 61
27890095 2016
24
Ovarian Cystadenoma in a Trafficked Patient. 61
27244785 2016
25
Redundant plantar skin folds. 61
28002528 2016
26
Endometrial stromal nodule - a case report. 61
25725687 2015
27
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. 61
25404834 2014
28
Pseudomixoma peritonei, a rare entity difficult to diagnose and treat - case report. 61
25560512 2014
29
The unique case of foot drop secondary to a large ovarian cyst. 61
24447226 2014
30
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). 61
25000708 2014
31
Perioperative management for the removal of a massive ovarian cystadenoma. 61
25612086 2013
32
Massive Hematometra due to Congenital Cervicovaginal Agenesis in an Adolescent Girl Treated by Hysterectomy: A Case Report. 61
23533866 2013
33
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. 61
21792894 2012
34
AT-rich sequence binding protein 1: Contribution to tumor progression and metastasis of human ovarian carcinoma. 61
22741008 2012
35
Abnormal ¹³¹I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. 61
22310273 2012
36
Reduced CMTM5 expression correlates with carcinogenesis in human epithelial ovarian cancer. 61
21841490 2011
37
FSH inhibits ovarian cancer cell apoptosis by up-regulating survivin and down-regulating PDCD6 and DR5. 61
20943720 2011
38
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. 61
24396716 2011
39
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. 61
21921381 2011
40
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. 61
20819672 2010
41
Expression of peptidylarginine deiminase type 4 in ovarian tumors. 61
20827398 2010
42
[Various acute phase reactants in different types of proliferative diseases of the uterine appendages]. 61
20000108 2009
43
[Ovarian cystadenoma and ectopic pregnancy. A case report]. 61
19902630 2009
44
The expression and significance of Dickkopf-1 in epithelial ovarian carcinoma. 61
19787627 2009
45
[Expression of ZNF217 in human ovarian cystadenocarcinoma and its clinical significance]. 61
19403395 2009
46
Serous and seromucinous infantile ovarian cystadenomas--a study of 42 cases. 61
18996636 2009
47
Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma. 61
18574502 2008
48
Peutz-Jegher's syndrome with ovarian serous cystadenoma: an unusual association. 61
18306547 2007
49
Increased chromosomal stability in cultures of ovarian tumours of low malignant potential compared to cystadenomas. 61
17519898 2007
50
Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. 61
17179812 2007

Variations for Ovarian Cystadenoma

Expression for Ovarian Cystadenoma

Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for Ovarian Cystadenoma

Pathways related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.97 SELE CLDN4 CLDN3

GO Terms for Ovarian Cystadenoma

Cellular components related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.17 SELE MUC16 GAST FBLN7 CMTM5 CLU
2 apicolateral plasma membrane GO:0016327 9.16 CLDN4 CLDN3
3 tight junction GO:0070160 8.96 CLDN4 CLDN3

Biological processes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell morphogenesis GO:0022604 9.4 CLDN4 CLDN3
2 positive regulation of wound healing GO:0090303 9.37 CLDN4 CLDN3
3 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 9.32 CLDN4 CLDN3
4 negative regulation of release of cytochrome c from mitochondria GO:0090201 9.26 LMNA CLU
5 epithelial cell morphogenesis GO:0003382 9.16 VSIG1 CLDN3
6 cell adhesion GO:0007155 9.1 SELE MUC16 FBLN7 CLDN4 CLDN3 CEACAM5
7 positive regulation of metallopeptidase activity GO:1905050 8.96 CLDN4 CLDN3

Sources for Ovarian Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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