MCID: OVR048
MIFTS: 31

Ovarian Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystadenoma

MalaCards integrated aliases for Ovarian Cystadenoma:

Name: Ovarian Cystadenoma 12 56 15 74
Simple Cystoma of the Ovary 12
Cystoma Serosum Simplex 12
Simple Cystoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3269
NCIt 51 C4060
UMLS 74 C0346169

Summaries for Ovarian Cystadenoma

Disease Ontology : 12 An ovarian benign neoplasm that has material basis in glandular epithelial tissue in which cystic accumulations of retained secretions are formed.

MalaCards based summary : Ovarian Cystadenoma, also known as simple cystoma of the ovary, is related to mucinous ovarian cystadenoma and ovarian papillary cystadenoma. An important gene associated with Ovarian Cystadenoma is BRCA1 (BRCA1 DNA Repair Associated), and among its related pathways/superpathways are Validated targets of C-MYC transcriptional repression and ATF-2 transcription factor network. The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include ovary, bone and pancreas, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 77 Ovarian cystadenoma is a cystic benign tumor of the ovary. Two types are recognized: serous and... more...

Related Diseases for Ovarian Cystadenoma

Graphical network of the top 20 diseases related to Ovarian Cystadenoma:



Diseases related to Ovarian Cystadenoma

Symptoms & Phenotypes for Ovarian Cystadenoma

GenomeRNAi Phenotypes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

27 (show all 18)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-122 10.21 ZNF217
2 Increased shRNA abundance (Z-score > 2) GR00366-A-127 10.21 ZNF217
3 Increased shRNA abundance (Z-score > 2) GR00366-A-131 10.21 LMNA ZNF217
4 Increased shRNA abundance (Z-score > 2) GR00366-A-147 10.21 ZNF217
5 Increased shRNA abundance (Z-score > 2) GR00366-A-151 10.21 LMNA ZNF217 SELE
6 Increased shRNA abundance (Z-score > 2) GR00366-A-159 10.21 ZNF217
7 Increased shRNA abundance (Z-score > 2) GR00366-A-161 10.21 ZNF217
8 Increased shRNA abundance (Z-score > 2) GR00366-A-186 10.21 ZNF217
9 Increased shRNA abundance (Z-score > 2) GR00366-A-189 10.21 SELE
10 Increased shRNA abundance (Z-score > 2) GR00366-A-19 10.21 SELE
11 Increased shRNA abundance (Z-score > 2) GR00366-A-25 10.21 ZNF217
12 Increased shRNA abundance (Z-score > 2) GR00366-A-39 10.21 SELE
13 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.21 ZNF217
14 Increased shRNA abundance (Z-score > 2) GR00366-A-67 10.21 ZNF217
15 Increased shRNA abundance (Z-score > 2) GR00366-A-83 10.21 ZNF217
16 Increased shRNA abundance (Z-score > 2) GR00366-A-90 10.21 LMNA
17 Increased shRNA abundance (Z-score > 2) GR00366-A-99 10.21 ZNF217
18 Upregulation of Wnt/beta-catenin pathway after WNT3A stimulation GR00016-A 8.8 BRCA1 FH LMNA

MGI Mouse Phenotypes related to Ovarian Cystadenoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 BRCA1 CLU FH LMNA

Drugs & Therapeutics for Ovarian Cystadenoma

Drugs for Ovarian Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved 33069-62-4 36314
2 Albumin-Bound Paclitaxel

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Ovarian Clear Cell Adenocarcinoma Review Completed NCT02129036

Search NIH Clinical Center for Ovarian Cystadenoma

Genetic Tests for Ovarian Cystadenoma

Anatomical Context for Ovarian Cystadenoma

MalaCards organs/tissues related to Ovarian Cystadenoma:

42
Ovary, Bone, Pancreas

Publications for Ovarian Cystadenoma

Articles related to Ovarian Cystadenoma:

(show all 32)
# Title Authors Year
1
Ovarian Cystadenoma in a Trafficked Patient. ( 27244785 )
2016
2
Ruptured benign serous ovarian cystadenoma mimicking ovarian malignancy with peritoneal carcinomatosis. ( 27421673 )
2016
3
An unexpected death due to massive ascites and a giant mucinous ovarian cystadenoma. ( 27890095 )
2016
4
Presacral epidermoid cyst in an elderly female, mistaken for ovarian cystadenoma. ( 25404834 )
2014
5
Bilateral ovarian cystadenoma in a geriatric African elephant (Loxodonta africana). ( 25000708 )
2014
6
Perioperative management for the removal of a massive ovarian cystadenoma. ( 25612086 )
2013
7
Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells. ( 21792894 )
2012
8
Abnormal ¹³¹I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. ( 22310273 )
2012
9
A woman with salt-wasting congenital adrenal hyperplasia presenting with a mucinous ovarian cystadenoma during pregnancy. ( 21921381 )
2011
10
Cutaneous and uterine leiomyomatosis and ovarian cystadenoma associated with deficiency of fumarate hydratase. ( 24396716 )
2011
11
Lamin C protein deficiency in the primary fibroblasts from a new laminopathy case with ovarian cystadenoma. ( 20819672 )
2010
12
Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. ( 17179812 )
2007
13
Rapidly growing bilateral ovarian cystadenoma in a 6-year-old girl: case report and literature review. ( 16472727 )
2006
14
Ovarian cystadenoma as a characteristic feature of families with hereditary ovarian cancers unassociated with BRCA1 and BRCA2 mutations. ( 15131356 )
2004
15
Tuberculous peritonitis with sonographic features of an ovarian cystadenoma. ( 14510274 )
2003
16
Massive ovarian cystadenoma detected solely on the blood-pool phase of a bone scan. ( 12045453 )
2002
17
Periampullary carcinoma with bilateral ovarian cystadenoma in pregnancy. ( 9563228 )
1998
18
Extremely high levels of CA19-9 and CA125 antigen in benign mucinous ovarian cystadenoma. ( 7508878 )
1994
19
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein. ( 1382586 )
1992
20
Clinicostatistical study of low potential malignancy ovarian cystadenoma (borderline cases). ( 1867577 )
1991
21
"Pseudoascites" secondary to an amylase-producing serous ovarian cystadenoma. A case study. ( 2479672 )
1989
22
Ovarian cystadenoma with stromal cell hyperplasia and postmenopausal virilization: a case report. ( 3169360 )
1988
23
Borderline ovarian cystadenoma. Spontaneous rupture and reaccumulation documented by ultrasound. ( 3286886 )
1988
24
A plasminogen activator from benign ovarian cystadenoma: partial purification and characterization. ( 3961743 )
1986
25
Cystic parametrial fibroids mimicking ovarian cystadenoma. ( 6726872 )
1984
26
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. ( 7365959 )
1980
27
A benign serous ovarian cystadenoma studied by chromosome and quantitative DNA analysis. ( 274883 )
1977
28
Virilization in pregnancy associated with an ovarian cystadenoma. ( 4416869 )
1974
29
Acute abdominal symptoms due to torsion of an ovarian cystadenoma in a centenarian. ( 5053461 )
1972
30
Chromosomal aberrations in an ovarian cystadenoma. ( 4185609 )
1969
31
Free and conjugated estrogens of an ovarian cystadenoma and granulosa cell tumor. ( 4284085 )
1965
32
PSEUDOMYXOMA PERITONAEI SECONDARY TO OVARIAN CYSTADENOMA. ( 20317773 )
1930

Variations for Ovarian Cystadenoma

Expression for Ovarian Cystadenoma

Search GEO for disease gene expression data for Ovarian Cystadenoma.

Pathways for Ovarian Cystadenoma

Pathways related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.74 BRCA1 CLU
2 10.36 BRCA1 SELE

GO Terms for Ovarian Cystadenoma

Biological processes related to Ovarian Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.13 BRCA1 CLU LMNA
2 negative regulation of release of cytochrome c from mitochondria GO:0090201 8.62 CLU LMNA

Sources for Ovarian Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....