MCID: OVR017
MIFTS: 31

Ovarian Cystic Teratoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystic Teratoma

MalaCards integrated aliases for Ovarian Cystic Teratoma:

Name: Ovarian Cystic Teratoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5118
NCIt 50 C7283
UMLS 73 C1335155

Summaries for Ovarian Cystic Teratoma

MalaCards based summary : Ovarian Cystic Teratoma is related to cystic teratoma and malignant syringoma. An important gene associated with Ovarian Cystic Teratoma is NECTIN2 (Nectin Cell Adhesion Molecule 2), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. Affiliated tissues include b cells, pituitary and colon.

Related Diseases for Ovarian Cystic Teratoma

Diseases related to Ovarian Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 125)
# Related Disease Score Top Affiliating Genes
1 cystic teratoma 32.0 KRT20 KRT7 NKX2-1
2 malignant syringoma 31.0 KRT20 KRT7
3 athyreosis 10.9 NKX2-1 TG
4 cystic basal cell carcinoma 10.9 KRT20 KRT7
5 vaginal benign neoplasm 10.9 KRT20 KRT7
6 seminal vesicle adenocarcinoma 10.9 KRT20 KRT7
7 transverse colon cancer 10.9 KRT20 KRT7
8 appendix adenocarcinoma 10.9 KRT20 KRT7
9 solid adenocarcinoma with mucin production 10.9 KRT7 NKX2-1
10 ovarian large-cell neuroendocrine carcinoma 10.9 KRT20 KRT7
11 vaginal adenoma 10.9 KRT20 KRT7
12 vaginal tubulovillous adenoma 10.9 KRT20 KRT7
13 struma ovarii 10.9 NKX2-1 TG
14 eyelid neoplasm 10.8 KRT20 KRT7
15 glandular cystitis 10.8 KRT20 KRT7
16 krukenberg carcinoma 10.8 KRT20 KRT7
17 malignant teratoma 10.8 NKX2-1 TG
18 large intestine adenocarcinoma 10.8 KRT20 KRT7
19 linitis plastica 10.8 KRT20 KRT7
20 adenoid squamous cell carcinoma 10.8 KRT20 KRT7
21 eccrine sweat gland neoplasm 10.8 KRT20 KRT7
22 transient neonatal neutropenia 10.8 FCGR3A FCGR3B
23 vulval paget's disease 10.8 KRT20 KRT7
24 bile duct cystadenocarcinoma 10.8 KRT20 KRT7
25 intratubular embryonal carcinoma 10.8 KRT20 KRT7
26 papillary adenoma 10.8 KRT7 NKX2-1
27 malignant struma ovarii 10.8 NKX2-1 TG
28 ovarian mucinous adenocarcinoma 10.8 KRT20 KRT7
29 thymus adenocarcinoma 10.8 KRT20 KRT7
30 rete testis adenocarcinoma 10.8 KRT20 NKX2-1
31 gastric diffuse adenocarcinoma 10.7 KRT20 KRT7
32 meibomian cyst 10.7 KRT20 KRT7
33 bronchiolo-alveolar adenocarcinoma 10.7 KRT7 NKX2-1
34 bladder lymphoma 10.7 KRT20 KRT7
35 teratoma 10.7
36 mucoepidermoid thyroid carcinoma 10.7 CALCA TG
37 bladder adenocarcinoma 10.7 KRT20 KRT7
38 spastic paraplegia 32, autosomal recessive 10.7 FCGR3A FCGR3B
39 basilar artery insufficiency 10.7 CALCA PVR
40 suppurative thyroiditis 10.7 CALCA TG
41 thyroid sarcoma 10.7 CALCA TG
42 jejunal adenocarcinoma 10.7 KRT20 KRT7
43 hypothyroidism, congenital, nongoitrous, 2 10.7 NKX2-1 TG
44 chronic cystitis 10.6 KRT20 KRT7
45 atypical follicular adenoma 10.6 CALCA TG
46 lung acinar adenocarcinoma 10.6 KRT20 KRT7 NKX2-1
47 small cell carcinoma of the bladder 10.6 KRT20 KRT7 NKX2-1
48 cystadenofibroma 10.6 KRT20 KRT7 TG
49 mucinous bronchioloalveolar adenocarcinoma 10.6 KRT20 KRT7 NKX2-1
50 papillary serous adenocarcinoma 10.6 KRT20 KRT7 NKX2-1

Graphical network of the top 20 diseases related to Ovarian Cystic Teratoma:



Diseases related to Ovarian Cystic Teratoma

Symptoms & Phenotypes for Ovarian Cystic Teratoma

Drugs & Therapeutics for Ovarian Cystic Teratoma

Search Clinical Trials , NIH Clinical Center for Ovarian Cystic Teratoma

Genetic Tests for Ovarian Cystic Teratoma

Anatomical Context for Ovarian Cystic Teratoma

MalaCards organs/tissues related to Ovarian Cystic Teratoma:

41
B Cells, Pituitary, Colon, Thymus

Publications for Ovarian Cystic Teratoma

Articles related to Ovarian Cystic Teratoma:

(show top 50) (show all 66)
# Title Authors Year
1
Mature ovarian cystic teratoma containing well-differentiated cerebellar tissue. ( 29949297 )
2017
2
Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. ( 28643027 )
2017
3
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 29016386 )
2017
4
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. ( 26980033 )
2016
5
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma. ( 24715550 )
2014
6
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. ( 25439346 )
2014
7
Huge Benign Ovarian Cystic Teratoma in a Patient with a History of Hansen's Disease. ( 25210635 )
2014
8
Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis. ( 24575020 )
2014
9
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma. ( 24584638 )
2014
10
A floating ball: a pathognomonic sign of ovarian cystic teratoma. ( 23764514 )
2013
11
Mature ovarian cystic teratoma (dermoid cyst). ( 22902841 )
2012
12
Conservative surgery in the management of a benign ovarian cystic teratoma presenting as a rectal mass: a case report. ( 21943447 )
2011
13
Intestinal obstruction due to bilateral ovarian cystic teratoma in a pregnant woman: report of a case. ( 21987947 )
2011
14
An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report. ( 20544870 )
2010
15
Ovarian cystic teratoma torsion in pregnancy. ( 20810465 )
2010
16
Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl. ( 19576813 )
2009
17
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 19317266 )
2009
18
A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. ( 19521124 )
2009
19
Ovarian cystic teratoma with a pathognomonic appearance of multiple floating balls: a case report and investigation of common characteristics of the cases in the literature. ( 18304549 )
2008
20
Ruptured ovarian cystic teratoma in pregnancy with diffuse peritoneal reaction mimicking advanced ovarian malignancy: a case report. ( 18549490 )
2008
21
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. ( 18581775 )
2008
22
Giant mature ovarian cystic teratoma including more than 300 teeth. ( 18280952 )
2008
23
Ruptured ovarian cystic teratoma secondary to blunt abdominal trauma: a very unusual case. ( 17308491 )
2007
24
Pathogenesis of balls in mature ovarian cystic teratoma. Report of 3 cases and review of literature. ( 16990711 )
2006
25
Floating ball appearance in ovarian cystic teratoma. ( 16972218 )
2006
26
Are they spherules of ovarian cystic teratoma or daughter cysts of echinococcosis? ( 17146747 )
2006
27
Unusual fast-growing ovarian cystic teratoma during pregnancy presenting with intracystic fat "floating balls" appearance. ( 17067585 )
2006
28
Ovarian cystic teratoma with primary epithelial cell melanoma. ( 15755005 )
2005
29
Metastatic malignant melanoma arising in a mature ovarian cystic teratoma: a case report and literature review. ( 16343199 )
2005
30
Monolateral mature ovarian cystic teratoma. ( 15746800 )
2005
31
MR and ultrasound imaging of floating globules in mature ovarian cystic teratoma. ( 15205564 )
2004
32
Mature ovarian cystic teratoma with a highly differentiated homunculus: a case report. ( 14745894 )
2004
33
Adenocarcinoma arising from respiratory ciliated epithelium in mature ovarian cystic teratoma. ( 12439559 )
2002
34
Ovarian cystic teratoma: determined phenotypic response of keratocytes and uncommon intracystic floating balls appearance on sonography and computed tomography. ( 12054308 )
2002
35
Small bowel perforation with minor trauma: a rare complication of an ovarian cystic teratoma. ( 12435956 )
2002
36
Primary malignant melanoma in ovarian cystic teratoma. ( 11531299 )
2001
37
Unusual "floating balls" appearance of an ovarian cystic teratoma: sonographic and CT findings. ( 11180183 )
2001
38
Amelanotic malignant melanoma arising in an ovarian cystic teratoma: a case report. ( 11575655 )
2001
39
Analysis of 20 mature ovarian cystic teratoma cases in postmenopausal women. ( 11780192 )
2001
40
Radiology case of the month. Abdominal mass. Bilateral ovarian cystic teratoma. ( 10851824 )
2000
41
Thymus tissue in ovarian cystic teratoma: possible clues to its histogenesis. ( 11186178 )
2000
42
Conservative management of ovarian cystic teratoma during pregnancy and labor. ( 10739498 )
2000
43
Primary malignant melanoma arising in an ovarian cystic teratoma. ( 9743462 )
1998
44
Mature ovarian cystic teratoma with combined squamous cell carcinoma and malignant melanoma. ( 9808441 )
1998
45
Malignant melanoma arising in mature ovarian cystic teratoma (dermoid cyst). Report of two cases and literature analysis. ( 8886884 )
1996
46
Residents' corner. Answer to case of the month #41. Mature ovarian cystic teratoma. ( 8857976 )
1996
47
p53 mutation in carcinomas arising in ovarian cystic teratomas. ( 8548037 )
1995
48
Small-cell epidermoid carcinoma with melanocyte colonization arising in a mature ovarian cystic teratoma. ( 7605174 )
1995
49
Radiology rounds. Ovarian cystic teratoma (ovarian dermoid). ( 7950466 )
1994
50
Combined microcystic adnexal carcinoma and squamous cell carcinoma arising in the ovarian cystic teratoma--a brief case report. ( 7702793 )
1994

Variations for Ovarian Cystic Teratoma

Expression for Ovarian Cystic Teratoma

Search GEO for disease gene expression data for Ovarian Cystic Teratoma.

Pathways for Ovarian Cystic Teratoma

GO Terms for Ovarian Cystic Teratoma

Cellular components related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 B2M CALCA FCGR3B GAST IFNA2 PRL
2 cell surface GO:0009986 9.55 ADAM17 B2M CD226 NECTIN2 PVR
3 cell-cell adherens junction GO:0005913 9.13 CD226 NECTIN2 PVR
4 external side of plasma membrane GO:0009897 8.92 B2M CD226 CD276 FCGR3A

Biological processes related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.88 CALCA GAST IFNA2 PRL TG
2 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 9.63 CD226 NECTIN2 PVR
3 positive regulation of T cell receptor signaling pathway GO:0050862 9.49 CD226 NECTIN2
4 positive regulation of mast cell activation GO:0033005 9.43 CD226 NECTIN2
5 cell recognition GO:0008037 9.43 CD226 NECTIN2 PVR
6 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.4 NECTIN2 PVR
7 positive regulation of immunoglobulin mediated immune response GO:0002891 9.37 CD226 NECTIN2
8 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.33 CD226 NECTIN2 PVR
9 susceptibility to T cell mediated cytotoxicity GO:0060370 9.32 NECTIN2 PVR
10 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 9.26 CD226 NECTIN2 PVR SLAMF6
11 regulation of immune response GO:0050776 9.17 B2M CD226 CD276 FCGR3A NECTIN2 PVR

Molecular functions related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.35 CALCA CD226 CD276 NECTIN2 PVR
2 cell adhesion molecule binding GO:0050839 9.33 CD226 NECTIN2 PVR
3 IgG binding GO:0019864 9.26 FCGR3A FCGR3B
4 hormone activity GO:0005179 8.92 CALCA GAST PRL TG

Sources for Ovarian Cystic Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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