MCID: OVR017
MIFTS: 28

Ovarian Cystic Teratoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Ovarian Cystic Teratoma

MalaCards integrated aliases for Ovarian Cystic Teratoma:

Name: Ovarian Cystic Teratoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5118
NCIt 49 C7283
UMLS 71 C1335155

Summaries for Ovarian Cystic Teratoma

Disease Ontology : 12 A cystic teratoma that is located in the ovary.

MalaCards based summary : Ovarian Cystic Teratoma is related to cystic teratoma and ovarian germ cell teratoma. An important gene associated with Ovarian Cystic Teratoma is SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include ovary, thyroid and b cells.

Related Diseases for Ovarian Cystic Teratoma

Diseases related to Ovarian Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Related Disease Score Top Affiliating Genes
1 cystic teratoma 31.1 NKX2-1 AFP
2 ovarian germ cell teratoma 29.9 SIGLEC5 NKX2-1 AFP
3 benign teratoma 29.9 NKX2-1 AFP
4 ovarian germ cell cancer 29.5 NKX2-1 AFP
5 teratoma 11.0
6 mature teratoma 10.5
7 melanoma, cutaneous malignant 10 10.4
8 melanoma 10.4
9 teratoma, ovarian 10.4
10 ovarian cyst 10.3
11 ovarian melanoma 10.2
12 peritonitis 10.2
13 germ cells tumors 10.2
14 adult type testicular granulosa cell tumor 10.2 MLANA AFP
15 hepatic angiomyolipoma 10.2 MLANA AFP
16 angiomyolipoma 10.1 MLANA AFP
17 ovarian cancer 10.1
18 diffuse large b-cell lymphoma 10.1
19 lymphoma 10.1
20 echinococcosis 10.1
21 b-cell lymphoma 10.1
22 thyroid cancer, nonmedullary, 1 10.0
23 myeloma, multiple 10.0
24 endometrial cancer 10.0
25 small cell carcinoma 10.0
26 ovarian benign neoplasm 10.0
27 pneumothorax 10.0
28 squamous cell carcinoma 10.0
29 struma ovarii 10.0
30 adenocarcinoma 10.0
31 germ cell cancer 10.0
32 pituitary adenoma 10.0
33 carcinosarcoma 10.0
34 mucoepidermoid carcinoma 10.0
35 sebaceous adenocarcinoma 10.0
36 dermoid cyst of ovary 10.0
37 malignant syringoma 10.0
38 adenoma 10.0
39 neuroblastoma 10.0
40 intestinal obstruction 10.0
41 in situ carcinoma 10.0
42 pulmonary embolism 10.0
43 47,xyy 10.0
44 hansen's disease 10.0
45 ovarian epithelial cancer 10.0
46 tièche-jadassohn nevus 10.0
47 rare tumor 10.0
48 thyroid carcinoma 10.0
49 thymus clear cell carcinoma 9.8 NKX2-1 MLANA
50 lymphangitis 9.8 SIGLEC5 NKX2-1

Graphical network of the top 20 diseases related to Ovarian Cystic Teratoma:



Diseases related to Ovarian Cystic Teratoma

Symptoms & Phenotypes for Ovarian Cystic Teratoma

Drugs & Therapeutics for Ovarian Cystic Teratoma

Search Clinical Trials , NIH Clinical Center for Ovarian Cystic Teratoma

Genetic Tests for Ovarian Cystic Teratoma

Anatomical Context for Ovarian Cystic Teratoma

The Foundational Model of Anatomy Ontology organs/tissues related to Ovarian Cystic Teratoma:

19
Ovary

MalaCards organs/tissues related to Ovarian Cystic Teratoma:

40
Ovary, Thyroid, B Cells, Thymus, Small Intestine, Colon, Liver

Publications for Ovarian Cystic Teratoma

Articles related to Ovarian Cystic Teratoma:

(show top 50) (show all 117)
# Title Authors PMID Year
1
The Poké Ball sign in mature ovarian cystic teratoma. 61
32500238 2020
2
Mature ovarian cystic teratoma with "sack of marbles" appearance on magnetic resonance imaging: A case report. 61
31374057 2019
3
Utility of the "floating ball sign" in diagnosis of ovarian cystic teratoma. 61
31360586 2019
4
Chemical peritonitis resulting from spontaneous rupture of a mature ovarian cystic teratoma: a case report. 61
32355460 2019
5
Live birth following laparoscopic fertility-sparing surgery for papillary thyroid carcinoma arising from mature ovarian cystic teratoma: A case report. 61
30546889 2018
6
Immune checkpoint inhibitors of CTLA4 and PD-1 for malignant melanoma arising in ovarian cystic teratoma: A case report. 61
30412106 2018
7
Superinfection of mature ovarian cystic teratoma in a child: An unusual presentation. 61
30197369 2018
8
Mature ovarian cystic teratoma with disseminated nodular lesions in the pleural and peritoneal cavities: A case report. 61
30042811 2018
9
A rare melanoma feature with primary ovarian origin: a case report and the literature review. 61
29564322 2018
10
Ovarian teratoma: yet another cause of immune thrombocytopenia. 61
30323687 2018
11
A Rare Malignant Transformation of an Ovarian Cystic Teratoma: A Case Report. 61
30112238 2018
12
Primary malignant melanoma arising in an ovarian cystic teratoma. 61
29016386 2017
13
Unusual presentation of plasmablastic lymphoma involving ovarian mature cystic teratoma: a case report. 61
29187222 2017
14
Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. 61
28643027 2017
15
'Sack of marbles' in mature cystic ovarian teratoma. 61
28138731 2017
16
Treatment and follow-up in an asymptomatic malignant struma ovarii: A case report. 61
28982046 2017
17
Mature ovarian cystic teratoma containing well-differentiated cerebellar tissue. 61
29949297 2017
18
[Transarterial Chemoembolization for Liver Metastasis of Ovarian Malignant Melanoma Resulting in Long-Term Survival]. 61
28133122 2016
19
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. 61
26980033 2016
20
HDLive ultrasound images of ovarian dermoid cysts: diagnostic accuracy. 61
27048012 2016
21
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma. 61
24715550 2015
22
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. 61
25439346 2014
23
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma. 61
24584638 2014
24
Spontaneous discharging umbilical sinus secondary to infected cystic teratoma ovary: an atypical presentation. 61
24959477 2014
25
A floating ball: a pathognomonic sign of ovarian cystic teratoma. 61
23764514 2014
26
Sclerosing peritonitis occurring in association with juvenile granulosa cell tumour - a cause of concern. 61
24783102 2014
27
Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis. 61
24575020 2014
28
Huge Benign Ovarian Cystic Teratoma in a Patient with a History of Hansen's Disease. 61
25210635 2014
29
Primary malignant melanoma arising in a cystic teratoma. 61
24328003 2013
30
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. 61
21684182 2012
31
Mature ovarian cystic teratoma (dermoid cyst). 61
22902841 2012
32
[Prostatic tissue in a mature cystic teratoma of the ovary: report of one case]. 61
22552562 2012
33
Conservative surgery in the management of a benign ovarian cystic teratoma presenting as a rectal mass: a case report. 61
21943447 2011
34
Intestinal obstruction due to bilateral ovarian cystic teratoma in a pregnant woman: report of a case. 61
21987947 2011
35
Ovarian cystic teratoma torsion in pregnancy. 61
20810465 2010
36
An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report. 61
20544870 2010
37
Warm antibody autoimmune haemolytic anaemia associated with ovarian teratoma. 61
22750920 2010
38
Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl. 61
19576813 2009
39
Images in clinical urology. Floating balls appearance in testicular cystic teratoma. 61
19362339 2009
40
Oligodendroglioma arising in an ovarian mature cystic teratoma. 61
19483626 2009
41
A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. 61
19521124 2009
42
Primary malignant melanoma arising in an ovarian cystic teratoma. 61
19317266 2009
43
Ovarian cystic teratoma with a pathognomonic appearance of multiple floating balls: a case report and investigation of common characteristics of the cases in the literature. 61
18304549 2008
44
Ruptured ovarian cystic teratoma in pregnancy with diffuse peritoneal reaction mimicking advanced ovarian malignancy: a case report. 61
18549490 2008
45
Unusual presentation of acute ovarian torsion in an adolescent. 61
18410839 2008
46
Giant mature ovarian cystic teratoma including more than 300 teeth. 61
18280952 2008
47
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. 61
18581775 2008
48
A case of concomitant occurrence of struma ovarii and malignant transformation of cystic teratoma. 61
17652549 2007
49
Ruptured ovarian cystic teratoma secondary to blunt abdominal trauma: a very unusual case. 61
17308491 2007
50
Unusual fast-growing ovarian cystic teratoma during pregnancy presenting with intracystic fat "floating balls" appearance. 61
17067585 2006

Variations for Ovarian Cystic Teratoma

Expression for Ovarian Cystic Teratoma

Search GEO for disease gene expression data for Ovarian Cystic Teratoma.

Pathways for Ovarian Cystic Teratoma

GO Terms for Ovarian Cystic Teratoma

Cellular components related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.23 UPK2 UNC5CL SLAMF6 SIGLEC5 SIGLEC11 NECTIN2

Biological processes related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.67 SIGLEC5 SIGLEC11 NECTIN2 CD226
2 regulation of immune response GO:0050776 9.58 SLAMF6 NECTIN2 CD226
3 positive regulation of interferon-gamma production GO:0032729 9.43 SLAMF6 CD226
4 positive regulation of T cell receptor signaling pathway GO:0050862 9.32 NECTIN2 CD226
5 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.26 NECTIN2 CD226
6 positive regulation of mast cell activation GO:0033005 9.16 NECTIN2 CD226
7 positive regulation of immunoglobulin mediated immune response GO:0002891 8.96 NECTIN2 CD226
8 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 8.8 SLAMF6 NECTIN2 CD226

Molecular functions related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion molecule binding GO:0050839 8.96 NECTIN2 CD226
2 sialic acid binding GO:0033691 8.62 SIGLEC5 SIGLEC11

Sources for Ovarian Cystic Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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