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MCID: OVR017
MIFTS: 29

Ovarian Cystic Teratoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Ovarian Cystic Teratoma

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MalaCards integrated aliases for Ovarian Cystic Teratoma:

Name: Ovarian Cystic Teratoma 12 15 71

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases Reproductive diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5118
NCIt 50 C7283
UMLS 71 C1335155
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Summaries for Ovarian Cystic Teratoma

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Disease Ontology : 12 A cystic teratoma that is located in the ovary.

MalaCards based summary : Ovarian Cystic Teratoma is related to ovarian germ cell teratoma and benign teratoma. An important gene associated with Ovarian Cystic Teratoma is SIGLEC5 (Sialic Acid Binding Ig Like Lectin 5), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Cell adhesion molecules. Affiliated tissues include ovary, thyroid and thymus.

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Related Diseases for Ovarian Cystic Teratoma

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Diseases related to Ovarian Cystic Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 ovarian germ cell teratoma 30.4 SIGLEC5 NKX2-1 AFP
2 benign teratoma 30.2 NKX2-1 AFP
3 ovarian germ cell cancer 29.9 NKX2-1 AFP
4 cystic teratoma 10.9
5 teratoma 10.9
6 mature teratoma 10.5
7 melanoma 10.4
8 teratoma, ovarian 10.4
9 ovarian cyst 10.3
10 ovarian melanoma 10.2
11 adult type testicular granulosa cell tumor 10.2 MLANA AFP
12 hepatic angiomyolipoma 10.1 MLANA AFP
13 diffuse large b-cell lymphoma 10.1
14 lymphoma 10.1
15 echinococcosis 10.1
16 b-cell lymphoma 10.1
17 peritonitis 10.1
18 germ cells tumors 10.1
19 mucinous stomach adenocarcinoma 10.1 NKX2-1 MLANA
20 lymphangitis 10.1 SIGLEC5 NKX2-1
21 thymus clear cell carcinoma 10.0 NKX2-1 MLANA
22 sarcomatous intrahepatic cholangiocarcinoma 10.0 NKX2-1 AFP
23 uterus leiomyosarcoma 10.0 NKX2-1 MLANA
24 melanomatosis 10.0 PVR MLANA
25 uterine corpus sarcoma 10.0 NKX2-1 MLANA
26 mediastinal cancer 10.0 NKX2-1 AFP
27 bladder diverticulum 10.0
28 thyroid cancer, nonmedullary, 1 10.0
29 endometrial cancer 10.0
30 ovarian benign neoplasm 10.0
31 scoliosis 10.0
32 pneumothorax 10.0
33 adenocarcinoma 10.0
34 pituitary adenoma 10.0
35 carcinosarcoma 10.0
36 sebaceous adenocarcinoma 10.0
37 dermoid cyst of ovary 10.0
38 malignant syringoma 10.0
39 adenoma 10.0
40 neuroblastoma 10.0
41 intestinal obstruction 10.0
42 pulmonary embolism 10.0
43 hansen's disease 10.0
44 ovarian epithelial cancer 10.0
45 tièche-jadassohn nevus 10.0
46 rare tumor 10.0
47 thyroid carcinoma 10.0
48 perivascular epithelioid cell tumor 10.0 NKX2-1 MLANA
49 adenomatoid tumor 10.0 NKX2-1 AFP
50 respiratory system benign neoplasm 9.9 NKX2-1 MLANA

Graphical network of the top 20 diseases related to Ovarian Cystic Teratoma:



Diseases related to Ovarian Cystic Teratoma
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Symptoms & Phenotypes for Ovarian Cystic Teratoma

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Drugs & Therapeutics for Ovarian Cystic Teratoma

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Search Clinical Trials , NIH Clinical Center for Ovarian Cystic Teratoma

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Genetic Tests for Ovarian Cystic Teratoma

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Anatomical Context for Ovarian Cystic Teratoma

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The Foundational Model of Anatomy Ontology organs/tissues related to Ovarian Cystic Teratoma:

19
Ovary

MalaCards organs/tissues related to Ovarian Cystic Teratoma:

40
Ovary, Thyroid, Thymus, Small Intestine, Pituitary
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Publications for Ovarian Cystic Teratoma

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Articles related to Ovarian Cystic Teratoma:

(show top 50) (show all 118)
# Title Authors PMID Year
1
The Poké Ball sign in mature ovarian cystic teratoma. 61
32500238 2021
2
Oily Ascites Revealing a Spontaneous Rupture of a Mature Ovarian Cystic Teratoma. 61
32964191 2020
3
Mature Ovarian Cystic Teratoma Mimicking a Bladder Diverticulum in a 16-year-old Female. 61
32916187 2020
4
Mature ovarian cystic teratoma with "sack of marbles" appearance on magnetic resonance imaging: A case report. 61
31374057 2019
5
Utility of the "floating ball sign" in diagnosis of ovarian cystic teratoma. 61
31360586 2019
6
Chemical peritonitis resulting from spontaneous rupture of a mature ovarian cystic teratoma: a case report. 61
32355460 2019
7
Live birth following laparoscopic fertility-sparing surgery for papillary thyroid carcinoma arising from mature ovarian cystic teratoma: A case report. 61
30546889 2018
8
Immune checkpoint inhibitors of CTLA4 and PD-1 for malignant melanoma arising in ovarian cystic teratoma: A case report. 61
30412106 2018
9
Superinfection of mature ovarian cystic teratoma in a child: An unusual presentation. 61
30197369 2018
10
Mature ovarian cystic teratoma with disseminated nodular lesions in the pleural and peritoneal cavities: A case report. 61
30042811 2018
11
A rare melanoma feature with primary ovarian origin: a case report and the literature review. 61
29564322 2018
12
Ovarian teratoma: yet another cause of immune thrombocytopenia. 61
30323687 2018
13
A Rare Malignant Transformation of an Ovarian Cystic Teratoma: A Case Report. 61
30112238 2018
14
Primary malignant melanoma arising in an ovarian cystic teratoma. 61
29016386 2017
15
Unusual presentation of plasmablastic lymphoma involving ovarian mature cystic teratoma: a case report. 61
29187222 2017
16
Melanoma arising in an ovarian cystic teratoma: a systematic review of presentation, treatment, and outcomes. 61
28643027 2017
17
'Sack of marbles' in mature cystic ovarian teratoma. 61
28138731 2017
18
Treatment and follow-up in an asymptomatic malignant struma ovarii: A case report. 61
28982046 2017
19
Mature ovarian cystic teratoma containing well-differentiated cerebellar tissue. 61
29949297 2017
20
[Transarterial Chemoembolization for Liver Metastasis of Ovarian Malignant Melanoma Resulting in Long-Term Survival]. 61
28133122 2016
21
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. 61
26980033 2016
22
HDLive ultrasound images of ovarian dermoid cysts: diagnostic accuracy. 61
27048012 2016
23
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in an Ovarian Cystic Teratoma. 61
24715550 2015
24
Diffuse large B-cell lymphoma occurring in an ovarian cystic teratoma: expanding the spectrum of large B-cell lymphoma associated with chronic inflammation. 61
25439346 2014
25
Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma. 61
24584638 2014
26
Spontaneous discharging umbilical sinus secondary to infected cystic teratoma ovary: an atypical presentation. 61
24959477 2014
27
A floating ball: a pathognomonic sign of ovarian cystic teratoma. 61
23764514 2014
28
Sclerosing peritonitis occurring in association with juvenile granulosa cell tumour - a cause of concern. 61
24783102 2014
29
Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis. 61
24575020 2014
30
Huge Benign Ovarian Cystic Teratoma in a Patient with a History of Hansen's Disease. 61
25210635 2014
31
Primary malignant melanoma arising in a cystic teratoma. 61
24328003 2013
32
Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome. 61
21684182 2012
33
Mature ovarian cystic teratoma (dermoid cyst). 61
22902841 2012
34
[Prostatic tissue in a mature cystic teratoma of the ovary: report of one case]. 61
22552562 2012
35
Conservative surgery in the management of a benign ovarian cystic teratoma presenting as a rectal mass: a case report. 61
21943447 2011
36
Intestinal obstruction due to bilateral ovarian cystic teratoma in a pregnant woman: report of a case. 61
21987947 2011
37
Ovarian cystic teratoma torsion in pregnancy. 61
20810465 2010
38
An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report. 61
20544870 2010
39
Warm antibody autoimmune haemolytic anaemia associated with ovarian teratoma. 61
22750920 2010
40
Spontaneous rupture of benign ovarian cystic teratoma in a premenarcheal girl. 61
19576813 2009
41
Images in clinical urology. Floating balls appearance in testicular cystic teratoma. 61
19362339 2009
42
Oligodendroglioma arising in an ovarian mature cystic teratoma. 61
19483626 2009
43
A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. 61
19521124 2009
44
Primary malignant melanoma arising in an ovarian cystic teratoma. 61
19317266 2009
45
Ovarian cystic teratoma with a pathognomonic appearance of multiple floating balls: a case report and investigation of common characteristics of the cases in the literature. 61
18304549 2008
46
Ruptured ovarian cystic teratoma in pregnancy with diffuse peritoneal reaction mimicking advanced ovarian malignancy: a case report. 61
18549490 2008
47
Unusual presentation of acute ovarian torsion in an adolescent. 61
18410839 2008
48
Giant mature ovarian cystic teratoma including more than 300 teeth. 61
18280952 2008
49
Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. 61
18581775 2008
50
A case of concomitant occurrence of struma ovarii and malignant transformation of cystic teratoma. 61
17652549 2007
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Variations for Ovarian Cystic Teratoma

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Expression for Ovarian Cystic Teratoma

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Search GEO for disease gene expression data for Ovarian Cystic Teratoma.
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Pathways for Ovarian Cystic Teratoma

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Pathways related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Class I MHC mediated antigen processing and presentation 65
Show member pathways
 12.61 SLAMF6 SIGLEC5 SIGLEC11 PVR NECTIN2 CD226
2
Cell adhesion molecules 36
11.51 PVR NECTIN2 CD226
3
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 65
11.23 SLAMF6 SIGLEC5 SIGLEC11 PVR NECTIN2 CD226
4
FOXA2 and FOXA3 transcription factor networks 1
10.97 NKX2-1 AFP
5
Nectin adhesion pathway 1
10.65 PVR NECTIN2
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GO Terms for Ovarian Cystic Teratoma

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Cellular components related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.23 UPK2 SLAMF6 SIGLEC5 SIGLEC11 PVR NECTIN2

Biological processes related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.83 SIGLEC5 SIGLEC11 PVR NECTIN2 CD226
2 regulation of immune response GO:0050776 9.67 SLAMF6 PVR NECTIN2 CD226
3 positive regulation of interferon-gamma production GO:0032729 9.49 SLAMF6 CD226
4 adherens junction organization GO:0034332 9.48 PVR NECTIN2
5 positive regulation of T cell receptor signaling pathway GO:0050862 9.46 NECTIN2 CD226
6 positive regulation of mast cell activation GO:0033005 9.4 NECTIN2 CD226
7 susceptibility to natural killer cell mediated cytotoxicity GO:0042271 9.32 PVR NECTIN2
8 positive regulation of immunoglobulin mediated immune response GO:0002891 9.26 NECTIN2 CD226
9 susceptibility to T cell mediated cytotoxicity GO:0060370 9.16 PVR NECTIN2
10 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 9.13 PVR NECTIN2 CD226
11 positive regulation of natural killer cell mediated cytotoxicity GO:0045954 8.92 SLAMF6 PVR NECTIN2 CD226

Molecular functions related to Ovarian Cystic Teratoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 9.16 PVR NECTIN2
2 sialic acid binding GO:0033691 8.96 SIGLEC5 SIGLEC11
3 cell adhesion molecule binding GO:0050839 8.8 PVR NECTIN2 CD226
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Sources for Ovarian Cystic Teratoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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