MCID: OVR016
MIFTS: 23

Ovarian Endometrioid Stromal Sarcoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Endometrioid Stromal Sarcoma

MalaCards integrated aliases for Ovarian Endometrioid Stromal Sarcoma:

Name: Ovarian Endometrioid Stromal Sarcoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5169
NCIt 50 C40065
UMLS 70 C1518714 C4288544

Summaries for Ovarian Endometrioid Stromal Sarcoma

Disease Ontology : 12 An ovary sarcoma that arises from endometrial stromal tissue.

MalaCards based summary : Ovarian Endometrioid Stromal Sarcoma is related to vaginal endometrial stromal tumor and mixed endometrial stromal and smooth muscle tumor. An important gene associated with Ovarian Endometrioid Stromal Sarcoma is PHF1 (PHD Finger Protein 1). Affiliated tissues include ovary, and related phenotypes are cardiovascular system and cellular

Related Diseases for Ovarian Endometrioid Stromal Sarcoma

Diseases related to Ovarian Endometrioid Stromal Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 242)
# Related Disease Score Top Affiliating Genes
1 vaginal endometrial stromal tumor 10.3 MME CALD1
2 mixed endometrial stromal and smooth muscle tumor 10.3 MME CALD1
3 fallopian tube leiomyoma 10.3 MME CALD1
4 urethra leiomyoma 10.3 MME CALD1
5 fallopian tube benign neoplasm 10.3 MME CALD1
6 breast myofibroblastoma 10.3 MME CALD1
7 subareolar duct papillomatosis 10.3 MME CALD1
8 cervical mucinous adenocarcinoma 10.3 MME CALD1
9 nipple benign neoplasm 10.3 MME CALD1
10 adenofibroma 10.3 MME CALB2
11 atypical polypoid adenomyoma 10.3 MME CALD1
12 ovarian melanoma 10.3 CALD1 CALB2
13 cervical carcinosarcoma 10.3 MME CALB2
14 pacinian tumor 10.3 MME CALB2
15 pulmonary vein leiomyosarcoma 10.3 PGR CALD1
16 cervical adenomyoma 10.3 PGR MME
17 cervical benign neoplasm 10.3 PGR MME
18 lung leiomyoma 10.3 PGR CALD1
19 uterine corpus adenosarcoma 10.3 PGR MME
20 breast leiomyoma 10.3 PGR MME
21 fallopian tube endometriosis 10.3 PGR MME
22 mucocele of appendix 10.3 PGR MME
23 nephrogenic adenoma of the urethra 10.3 MME CALB2
24 bizarre leiomyoma 10.2 PGR CALD1
25 adult cystic nephroma 10.2 PGR MME
26 breast metaplastic carcinoma 10.2 PGR MME
27 bladder leiomyoma 10.2 CALD1 CALB2
28 breast malignant phyllodes tumor 10.2 PGR MME
29 adult type testicular granulosa cell tumor 10.2 PGR CALB2
30 bartholin's gland disease 10.2 PGR CALB2
31 cutaneous adenocystic carcinoma 10.2 PGR MME
32 intravascular angioleiomyoma 10.2 PECAM1 CALD1
33 benign breast phyllodes tumor 10.2 PGR MME
34 fallopian tube endometrioid adenocarcinoma 10.2 MME CALB2
35 uterus leiomyosarcoma 10.2 PGR CALD1
36 angiomyoma 10.2 PECAM1 CALD1
37 uterine corpus sarcoma 10.2 PGR CALD1
38 gallbladder leiomyosarcoma 10.2 PECAM1 CALD1
39 kidney sarcoma 10.2 YWHAE WT1
40 colon leiomyosarcoma 10.2 WT1 CALD1
41 intraductal breast benign neoplasm 10.2 PGR MME
42 subserous uterine fibroid 10.2 PGR CYP19A1
43 skin sarcoma 10.2 PECAM1 CALD1
44 pilar sheath acanthoma 10.2 MME CALB2
45 myxosarcoma 10.2 PECAM1 CALD1
46 intravascular fasciitis 10.2 PECAM1 CALD1
47 ovarian mixed germ cell neoplasm 10.2 WT1 MME
48 pulmonary artery leiomyosarcoma 10.2 PECAM1 MME
49 benign metastasizing leiomyoma 10.2 PGR CYP19A1
50 angiolipoma 10.2 PECAM1 CALD1

Graphical network of the top 20 diseases related to Ovarian Endometrioid Stromal Sarcoma:



Diseases related to Ovarian Endometrioid Stromal Sarcoma

Symptoms & Phenotypes for Ovarian Endometrioid Stromal Sarcoma

MGI Mouse Phenotypes related to Ovarian Endometrioid Stromal Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 AR CYP19A1 HDAC8 MME PECAM1 PGR
2 cellular MP:0005384 9.81 AR CYP19A1 HDAC8 MME PECAM1 PGR
3 muscle MP:0005369 9.43 AR CYP19A1 PECAM1 PGR WT1 YWHAE
4 normal MP:0002873 9.17 AR CALB2 CYP19A1 HDAC8 PGR SYP

Drugs & Therapeutics for Ovarian Endometrioid Stromal Sarcoma

Search Clinical Trials , NIH Clinical Center for Ovarian Endometrioid Stromal Sarcoma

Genetic Tests for Ovarian Endometrioid Stromal Sarcoma

Anatomical Context for Ovarian Endometrioid Stromal Sarcoma

MalaCards organs/tissues related to Ovarian Endometrioid Stromal Sarcoma:

40
Ovary

Publications for Ovarian Endometrioid Stromal Sarcoma

Articles related to Ovarian Endometrioid Stromal Sarcoma:

# Title Authors PMID Year
1
Removal of an endometrioid stromal sarcoma from the inferior vena cava and right atrium. 61
29488074 2019
2
Primary Ovarian Endometrioid Stromal Sarcoma Presenting with Infertility. 61
28511399 2017
3
Transformation of cultured rat ovarian surface epithelial cells by Kirsten murine sarcoma virus. 61
6263459 1981

Variations for Ovarian Endometrioid Stromal Sarcoma

Expression for Ovarian Endometrioid Stromal Sarcoma

Search GEO for disease gene expression data for Ovarian Endometrioid Stromal Sarcoma.

Pathways for Ovarian Endometrioid Stromal Sarcoma

GO Terms for Ovarian Endometrioid Stromal Sarcoma

Cellular components related to Ovarian Endometrioid Stromal Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection terminus GO:0044306 8.96 SYP MME
2 ESC/E(Z) complex GO:0035098 8.62 SUZ12 PHF1

Biological processes related to Ovarian Endometrioid Stromal Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intracellular steroid hormone receptor signaling pathway GO:0030518 8.96 PGR AR
2 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 8.62 PGR AR

Molecular functions related to Ovarian Endometrioid Stromal Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.61 WT1 SUZ12 PHF1 PGR MME HDAC8
2 RNA polymerase II transcription corepressor binding GO:0001226 9.16 SUZ12 PHF1
3 RNA polymerase II transcription coactivator binding GO:0001225 8.62 PGR AR

Sources for Ovarian Endometrioid Stromal Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....