MCID: OVR039
MIFTS: 22

Ovarian Mesodermal Adenosarcoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Mesodermal Adenosarcoma

MalaCards integrated aliases for Ovarian Mesodermal Adenosarcoma:

Name: Ovarian Mesodermal Adenosarcoma 12 15
Ovarian Mullerian Adenosarcoma 12
Ovarian Adenosarcoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4115
NCIt 49 C7317
UMLS 71 C1335169

Summaries for Ovarian Mesodermal Adenosarcoma

Disease Ontology : 12 An ovarian carcinosarcoma that derives from simultaneously or consecutively in mesodermal tissue and glandular epithelium.

MalaCards based summary : Ovarian Mesodermal Adenosarcoma, also known as ovarian mullerian adenosarcoma, is related to adenosarcoma and endometriosis. An important gene associated with Ovarian Mesodermal Adenosarcoma is PAX8 (Paired Box 8), and among its related pathways/superpathways is Regulation of Telomerase. Related phenotypes are cellular and embryo

Related Diseases for Ovarian Mesodermal Adenosarcoma

Diseases related to Ovarian Mesodermal Adenosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 adenosarcoma 10.2
2 endometriosis 10.2
3 overgrowth syndrome 10.2
4 fallopian tube endometrioid adenocarcinoma 10.1 PAX8 MYOG
5 vagina leiomyosarcoma 10.1 MYOG ESR1
6 vagina sarcoma 10.1 MYOG ESR1
7 hobnail hemangioma 10.0 WT1 MYOG
8 wilms tumor 5 10.0 WT1 PAX8
9 rhabdoid cancer 9.9 WT1 MYOG
10 sex development disorder 9.9 WT1 ESR1
11 ovarian serous carcinoma 9.9 WT1 PAX8
12 nephrogenic adenoma of urinary bladder 9.9 PAX8 KRT7
13 nephrogenic adenoma 9.9 PAX8 KRT7
14 wolffian duct adenoma 9.9 PAX8 KRT7
15 rete testis neoplasm 9.9 PAX8 KRT7
16 rete testis adenocarcinoma 9.9 PAX8 KRT7
17 peritoneal mesothelioma 9.9 WT1 ESR1
18 renal pelvis adenocarcinoma 9.9 PAX8 KRT7
19 urethral diverticulum 9.9 PAX8 KRT7
20 clear cell hidradenoma 9.9 PAX8 KRT7
21 nephrogenic adenoma of the urethra 9.9 PAX8 KRT7
22 urethral benign neoplasm 9.9 PAX8 KRT7
23 ovarian mucinous neoplasm 9.9 PAX8 KRT7
24 thymus clear cell carcinoma 9.9 PAX8 KRT7
25 thyroid angiosarcoma 9.9 PAX8 KRT7
26 nasal cavity olfactory neuroblastoma 9.9 PAX8 KRT7
27 urethra clear cell adenocarcinoma 9.9 PAX8 KRT7
28 cervical adenocarcinoma 9.9 KRT7 ESR1
29 bartholin's gland adenoid cystic carcinoma 9.9 KRT7 ESR1
30 mucinous adenofibroma 9.9 KRT7 ESR1
31 atrophic vulva 9.9 KRT7 ESR1
32 oncocytic breast carcinoma 9.9 KRT7 ESR1
33 bladder benign neoplasm 9.9 PAX8 KRT7
34 serous cystadenocarcinoma 9.9 WT1 PAX8
35 kidney benign neoplasm 9.9 PAX8 KRT7
36 leiomyomatosis 9.9 WT1 ESR1
37 breast metaplastic carcinoma 9.8 KRT7 ESR1
38 liver sarcoma 9.8 MYOG KRT7
39 skeletal muscle cancer 9.8 WT1 MYOG
40 renal hypodysplasia/aplasia 1 9.8 WT1 PAX8
41 endometrial clear cell adenocarcinoma 9.8 KRT7 ESR1
42 angiosarcoma 9.8 MYOG KRT7
43 muscle cancer 9.8 WT1 MYOG
44 apocrine adenocarcinoma 9.8 KRT7 ESR1
45 cervical mucinous adenocarcinoma 9.8 KRT7 ESR1
46 mucinous adenocarcinoma 9.8 KRT7 ESR1
47 adenomyoma 9.8 KRT7 ESR1
48 cribriform carcinoma 9.8 KRT7 ESR1
49 uterus leiomyosarcoma 9.8 MYOG KRT7
50 clear cell basal cell carcinoma 9.8 MYOG KRT7

Graphical network of the top 20 diseases related to Ovarian Mesodermal Adenosarcoma:



Diseases related to Ovarian Mesodermal Adenosarcoma

Symptoms & Phenotypes for Ovarian Mesodermal Adenosarcoma

MGI Mouse Phenotypes related to Ovarian Mesodermal Adenosarcoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.72 ESR1 KRT7 MYOG PAX8 WT1
2 embryo MP:0005380 9.56 ESR1 MYOG PAX8 WT1
3 no phenotypic analysis MP:0003012 9.46 ESR1 MYOG PAX8 WT1
4 normal MP:0002873 9.26 ESR1 MYOG PAX8 WT1
5 renal/urinary system MP:0005367 8.92 ESR1 KRT7 PAX8 WT1

Drugs & Therapeutics for Ovarian Mesodermal Adenosarcoma

Search Clinical Trials , NIH Clinical Center for Ovarian Mesodermal Adenosarcoma

Genetic Tests for Ovarian Mesodermal Adenosarcoma

Anatomical Context for Ovarian Mesodermal Adenosarcoma

Publications for Ovarian Mesodermal Adenosarcoma

Articles related to Ovarian Mesodermal Adenosarcoma:

# Title Authors PMID Year
1
Primary extra-uterine and extra-ovarian mullerian adenosarcoma: case report and literature review. 61
29402239 2018

Variations for Ovarian Mesodermal Adenosarcoma

Expression for Ovarian Mesodermal Adenosarcoma

Search GEO for disease gene expression data for Ovarian Mesodermal Adenosarcoma.

Pathways for Ovarian Mesodermal Adenosarcoma

Pathways related to Ovarian Mesodermal Adenosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.44 WT1 ESR1

GO Terms for Ovarian Mesodermal Adenosarcoma

Biological processes related to Ovarian Mesodermal Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of transcription, DNA-templated GO:0006355 9.73 WT1 PAX8 MYOG ESR1
2 positive regulation of transcription by RNA polymerase II GO:0045944 9.62 WT1 PAX8 MYOG ESR1
3 positive regulation of transcription, DNA-templated GO:0045893 9.56 WT1 PAX8 MYOG ESR1
4 kidney development GO:0001822 9.48 WT1 PAX8
5 male gonad development GO:0008584 9.46 WT1 ESR1
6 branching involved in ureteric bud morphogenesis GO:0001658 9.4 WT1 PAX8
7 cellular response to estradiol stimulus GO:0071392 9.37 MYOG ESR1
8 cellular response to gonadotropin stimulus GO:0071371 9.16 WT1 PAX8
9 metanephric S-shaped body morphogenesis GO:0072284 8.96 WT1 PAX8
10 metanephric epithelium development GO:0072207 8.62 WT1 PAX8

Molecular functions related to Ovarian Mesodermal Adenosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 9.56 WT1 PAX8 MYOG ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.5 PAX8 MYOG ESR1
3 DNA-binding transcription factor activity GO:0003700 9.46 WT1 PAX8 MYOG ESR1
4 sequence-specific DNA binding GO:0043565 9.26 WT1 PAX8 MYOG ESR1
5 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 8.92 WT1 PAX8 MYOG ESR1

Sources for Ovarian Mesodermal Adenosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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