MCID: OVR011
MIFTS: 35

Ovarian Mucinous Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Mucinous Adenocarcinoma

MalaCards integrated aliases for Ovarian Mucinous Adenocarcinoma:

Name: Ovarian Mucinous Adenocarcinoma 12 15 17 71
Mucinous Carcinoma of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3606
NCIt 49 C5243
UMLS 71 C1335167

Summaries for Ovarian Mucinous Adenocarcinoma

Disease Ontology : 12 An ovary adenocarcinoma that is characterized by the presence of mucin.

MalaCards based summary : Ovarian Mucinous Adenocarcinoma, also known as mucinous carcinoma of ovary, is related to appendix adenocarcinoma and teratoma. An important gene associated with Ovarian Mucinous Adenocarcinoma is CDX2 (Caudal Type Homeobox 2). The drugs Antibodies, Monoclonal and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include ovary, colon and appendix.

Related Diseases for Ovarian Mucinous Adenocarcinoma

Diseases related to Ovarian Mucinous Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 210)
# Related Disease Score Top Affiliating Genes
1 appendix adenocarcinoma 31.0 KRT7 KRT20 CDX2
2 teratoma 30.2 KRT7 KRT20 CDX2
3 adenoma 30.2 MUC5AC KRT7 CDX2
4 benign teratoma 30.2 KRT7 KRT20 CDX2
5 mucinous adenocarcinoma 30.1 MUC5AC KRT7 KRT20 CDX2 AMACR
6 colorectal adenocarcinoma 30.1 KRT7 KRT20 CDX2
7 ovarian mucinous neoplasm 30.0 MUC5AC KRT7 KRT20 CDX2
8 cystic teratoma 29.8 MUC5AC KRT7 KRT20 CDX2
9 cystadenoma 29.4 SERPINA3 MUC5AC KRT7 KRT20
10 pseudomyxoma peritonei 29.2 MUC5AC MUC2 KRT7 KRT20 CDX2
11 mucinous adenocarcinoma of ovary 11.9
12 adenocarcinoma 10.5
13 bladder signet ring cell adenocarcinoma 10.4 KRT7 CDX2
14 ovary neuroendocrine neoplasm 10.4 KRT7 CDX2
15 anal canal paget's disease 10.4 KRT7 CDX2
16 anal paget's disease 10.4 KRT7 CDX2
17 ureter adenocarcinoma 10.4 KRT7 CDX2
18 pancreatic foamy gland adenocarcinoma 10.4 KRT7 CDX2
19 adenosquamous colon carcinoma 10.4 KRT7 CDX2
20 nasal cavity adenocarcinoma 10.4 KRT7 CDX2
21 anus adenocarcinoma 10.4 KRT7 CDX2
22 mucinous adenofibroma 10.4 KRT7 CDX2
23 rectum neuroendocrine neoplasm 10.4 KRT7 CDX2
24 ovarian seromucinous carcinoma 10.4 KRT7 CDX2
25 appendiceal neoplasm 10.4 KRT7 CDX2
26 urethral villous adenoma 10.4 KRT7 KRT20
27 thymus adenocarcinoma 10.4 KRT20 CDX2
28 pancreatic serous cystadenocarcinoma 10.4 KRT7 KRT20
29 intrahepatic bile duct adenoma 10.4 KRT7 KRT20
30 bile duct adenoma 10.4 KRT7 KRT20
31 seminal vesicle adenocarcinoma 10.4 KRT7 KRT20
32 ovarian large-cell neuroendocrine carcinoma 10.4 KRT7 KRT20
33 esophageal adenosquamous carcinoma 10.4 KRT7 CDX2
34 atrophic vulva 10.4 KRT7 KRT20
35 small cell carcinoma of the bladder 10.4 KRT7 KRT20
36 aortic malignant tumor 10.4 KRT7 KRT20
37 urinary bladder small cell neuroendocrine carcinoma 10.4 KRT7 KRT20
38 colonic lymphangioma 10.4 KRT7 KRT20
39 vulvar apocrine adenocarcinoma 10.4 KRT7 KRT20
40 nasal cavity olfactory neuroblastoma 10.4 KRT7 CDX2
41 eyelid carcinoma 10.4 KRT7 KRT20
42 transverse colon cancer 10.4 KRT7 KRT20
43 nephrogenic adenoma 10.4 KRT7 AMACR
44 intratubular embryonal carcinoma 10.4 KRT7 KRT20
45 malignant syringoma 10.4 KRT7 KRT20
46 jejunal neoplasm 10.4 KRT7 KRT20
47 papillary transitional carcinoma 10.4 KRT7 KRT20
48 ovarian brenner tumor 10.4 KRT7 KRT20
49 eccrine sweat gland cancer 10.4 KRT7 KRT20
50 sweat gland cancer 10.4 KRT7 KRT20

Graphical network of the top 20 diseases related to Ovarian Mucinous Adenocarcinoma:



Diseases related to Ovarian Mucinous Adenocarcinoma

Symptoms & Phenotypes for Ovarian Mucinous Adenocarcinoma

Drugs & Therapeutics for Ovarian Mucinous Adenocarcinoma

Drugs for Ovarian Mucinous Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies, Monoclonal Phase 1
2 Immunoglobulins Phase 1
3 Antibodies Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 1 With Expansion Cohorts in a Study of NEO-201 in Adults With Chemo-Resistant Solid Tumors Recruiting NCT03476681 Phase 1 NEO-201

Search NIH Clinical Center for Ovarian Mucinous Adenocarcinoma

Genetic Tests for Ovarian Mucinous Adenocarcinoma

Anatomical Context for Ovarian Mucinous Adenocarcinoma

MalaCards organs/tissues related to Ovarian Mucinous Adenocarcinoma:

40
Ovary, Colon, Appendix, Kidney, Lung, Breast, Thyroid

Publications for Ovarian Mucinous Adenocarcinoma

Articles related to Ovarian Mucinous Adenocarcinoma:

(show all 40)
# Title Authors PMID Year
1
Significance of SATB2 expression in colon cancer and its differential diagnosis in digestive tract adenocarcinoma and ovarian primary and metastatic carcinoma. 61
31101576 2019
2
Response to "Novel" nomogram and algorithm do not aid in the distinction of primary vs. metastatic mucinous carcinoma of ovary: letter to the Editor. 61
31016434 2019
3
Anaplastic Carcinoma Arising From Ovarian Mucinous Adenocarcinoma With Massive Cardiopulmonary Metastasis: An Autopsy Case Report. 61
30393058 2019
4
Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy. 61
27899985 2016
5
Regulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma. 61
27060927 2016
6
Ovarian mucinous adenocarcinoma with functioning stroma in postmenopausal women: aromatase and SF-1 expressions. 61
26576867 2015
7
Ovarian mucinous tumor with malignant mural nodules: dedifferentiation or collision? 61
25473748 2015
8
Primary ovarian mucinous adenocarcinoma of intestinal type: a clinicopathologic study of 46 cases. 61
24487473 2014
9
Dual inhibition of phosphatidylinositol 3'-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach for mucinous adenocarcinoma of the ovary. 61
24552895 2014
10
Association of pancreatic adenocarcinoma up-regulated factor expression in ovarian mucinous adenocarcinoma with poor prognosis. 61
25197383 2014
11
Slow progression of calcified cerebellar metastasis from ovarian cancer: a case report and review of the literature. 61
24077275 2013
12
Pre-invasive ovarian mucinous tumors are characterized by CDKN2A and RAS pathway aberrations. 61
22891197 2012
13
A case of ovarian mucinous adenocarcinoma in a premenarcheal girl. 61
22016113 2012
14
Mucinous adenocarcinoma developed from human fallopian tube epithelial cells through defined genetic modifications. 61
22592533 2012
15
Differentiating rectal carcinoma by an immunohistological analysis of carcinomas of pelvic organs based on the NCBI Literature Survey and the Human Protein Atlas database. 61
22441574 2012
16
Prognostic significance of stromal microinvasion in the intestinal type of ovarian mucinous adenocarcinoma. 61
21556953 2011
17
Late presentation of a mucinous ovarian adenocarcinoma which was initially diagnosed as a primary pancreatic carcinoma: a case report and review of the literature. 61
20298585 2010
18
CK7, CK20, CDX2 and MUC2 Immunohistochemical staining used to distinguish metastatic colorectal carcinoma involving ovary from primary ovarian mucinous adenocarcinoma. 61
19926591 2010
19
High expression of N-acetylglucosaminyltransferase V in mucinous tumors of the ovary. 61
19787216 2009
20
Combination chemotherapy of oxaliplatin and 5-fluorouracil may be an effective regimen for mucinous adenocarcinoma of the ovary: a potential treatment strategy. 61
19154404 2009
21
Gingival metastasis from ovarian mucinous cystadenocarcinoma as an initial manifestation (a rare case report). 61
19246966 2008
22
Ovarian mature teratomas with mucinous epithelial neoplasms: morphologic heterogeneity and association with pseudomyxoma peritonei. 61
18344868 2008
23
Advanced epithelial ovarian carcinoma during pregnancy. 61
17929120 2007
24
Mucinous carcinoma of thyroid gland. Report of a primary and a metastatic mucinous tumour from ovarian adenocarcinoma with immunohistochemical study and review of literature. 61
17704943 2007
25
Immunohistochemical expression of SMAD4, CK19, and CA19-9 in fine needle aspiration samples of pancreatic adenocarcinoma: Utility and potential role. 61
17587453 2007
26
Triple simultaneous primary gynecological malignancies in a 56-year-old patient. 61
17009998 2006
27
[Role of CDX2 immunostaining in diagnosis of gastrointestinal adenocarcinoma]. 61
16776981 2006
28
Combined positron emission tomography and computed tomography for the detection of recurrent ovarian mucinous adenocarcinoma. 61
15721446 2005
29
Metastasis of small cell carcinoma of lung into an ovarian mucinous neoplasm: immunohistochemistry as a useful ancillary technique for diagnosis and classification of rare tumors. 61
15722802 2005
30
An ovarian mucinous adenocarcinoma arising from mature cystic teratoma associated with respiratory type tissue: a case report. 61
15656343 2004
31
Abdominal wall metastasis from ovarian cancer after laparotomy. A case report. 61
12556106 2002
32
Mucinous adenocarcinoma of the ovary metastatic to the eye: report of a case with diagnosis by fine needle aspiration biopsy. 61
11575663 2001
33
[Ovarian mucinous adenocarcinoma, mucocele of the appendix and pseudomyxoma peritonei: case report with immunohistochemical analysis]. 61
10756603 2000
34
Carcinoma of the ovary with primary presentation in the choroid. 61
10634571 1999
35
Identical, unique p53 mutations in a primary ovarian mucinous adenocarcinoma and a synchronous contralateral ovarian mucinous tumor of low malignant potential suggest a common clonal origin. 61
9158713 1997
36
Clinical evaluation of radioimmunoimaging with 131I-C0C183B2 monoclonal antibody against ovarian carcinoma by intraperitoneal injection. 61
1468700 1992
37
[In vitro studies on the expression of c-myc oncogene product in gynecological cultured cancer cells]. 61
1940543 1991
38
A preliminary study of radioimmunoimaging by 131I-COC183B2 monoclonal antibody in patients with epithelial ovarian cancer. 61
1874008 1991
39
[Characterization of immunoreactive hCG beta-subunit in cultured fluids of the cell lines derived from gynecologic malignant tumors]. 61
1703201 1990
40
[Reorganization of human ovarian adenocarcinoma cells and endometrial adenocarcinoma cells cultured in double-layered floating collagen gels]. 61
3027213 1986

Variations for Ovarian Mucinous Adenocarcinoma

Cosmic variations for Ovarian Mucinous Adenocarcinoma:

9 (show top 50) (show all 1465)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM101787718 WEE2 ovary,NS,carcinoma,mucinous carcinoma c.1193G>A p.R398H 7:141724247-141724247 6
2 COSM91622098 ULK1 ovary,NS,carcinoma,mucinous carcinoma c.868G>A p.V290M 12:131910720-131910720 6
3 COSM140618045 TTN ovary,NS,carcinoma,mucinous carcinoma c.4991G>A p.R1664Q 2:178776873-178776873 6
4 COSM85727873 TSC1 ovary,NS,carcinoma,mucinous carcinoma c.1997+1G>A p.? 9:132905580-132905580 6
5 COSM94315919 TRRAP ovary,NS,carcinoma,mucinous carcinoma c.5840G>T p.R1947L 7:98955228-98955228 6
6 COSM87905773 TP53 ovary,NS,carcinoma,adenocarcinoma c.542G>A p.R181H 17:7675070-7675070 6
7 COSM87901584 TP53 ovary,NS,carcinoma,mucinous carcinoma c.379T>C p.S127P 17:7675233-7675233 6
8 COSM87898723 TP53 ovary,NS,carcinoma,mucinous carcinoma c.817C>T p.R273C 17:7673803-7673803 6
9 COSM87897745 TP53 ovary,NS,carcinoma,mucinous carcinoma c.524G>A p.R175H 17:7675088-7675088 6
10 COSM87912881 TP53 ovary,NS,carcinoma,mucinous carcinoma c.643A>T p.S215C 17:7674888-7674888 6
11 COSM87915834 TP53 ovary,NS,carcinoma,mucinous carcinoma c.700T>C p.Y234H 17:7674263-7674263 6
12 COSM87898714 TP53 ovary,NS,carcinoma,mucinous carcinoma c.844C>T p.R282W 17:7673776-7673776 6
13 COSM87899076 TP53 ovary,NS,carcinoma,mucinous carcinoma c.673-1G>A p.? 17:7674291-7674291 6
14 COSM87908196 TP53 ovary,NS,carcinoma,mucinous carcinoma c.714T>G p.C238W 17:7674249-7674249 6
15 COSM87898709 TP53 ovary,NS,carcinoma,mucinous carcinoma c.742C>T p.R248W 17:7674221-7674221 6
16 COSM87898351 TP53 ovary,NS,carcinoma,mucinous carcinoma c.743G>A p.R248Q 17:7674220-7674220 6
17 COSM87897711 TP53 ovary,NS,carcinoma,mucinous carcinoma c.818G>A p.R273H 17:7673802-7673802 6
18 COSM87898578 TP53 ovary,NS,carcinoma,mucinous carcinoma c.733G>A p.G245S 17:7674230-7674230 6
19 COSM87905617 TP53 ovary,NS,carcinoma,mucinous carcinoma c.421T>C p.C141R 17:7675191-7675191 6
20 COSM87898991 TP53 ovary,NS,carcinoma,mucinous carcinoma c.535C>T p.H179Y 17:7675077-7675077 6
21 COSM87907551 TP53 ovary,NS,carcinoma,mucinous carcinoma c.581T>G p.L194R 17:7674950-7674950 6
22 COSM87902162 TP53 ovary,NS,carcinoma,mucinous carcinoma c.783-1G>T p.? 17:7673838-7673838 6
23 COSM87897627 TP53 ovary,NS,carcinoma,mucinous carcinoma c.574C>T p.Q192* 17:7674957-7674957 6
24 COSM87897883 TP53 ovary,NS,carcinoma,mucinous carcinoma c.659A>G p.Y220C 17:7674872-7674872 6
25 COSM87899223 TP53 ovary,NS,carcinoma,adenocarcinoma c.578A>T p.H193L 17:7674953-7674953 6
26 COSM87905926 TP53 ovary,NS,carcinoma,mucinous carcinoma c.434T>C p.L145P 17:7675178-7675178 6
27 COSM88220436 TP53 ovary,NS,carcinoma,mucinous carcinoma c.922C>G p.L308V 17:7673606-7673606 6
28 COSM87904406 TP53 ovary,NS,carcinoma,mucinous carcinoma c.796G>A p.G266R 17:7673824-7673824 6
29 COSM87898818 TP53 ovary,NS,carcinoma,adenocarcinoma c.916C>T p.R306* 17:7673704-7673704 6
30 COSM87897839 TP53 ovary,NS,carcinoma,mucinous carcinoma c.701A>G p.Y234C 17:7674262-7674262 6
31 COSM87914388 TP53 ovary,NS,carcinoma,mucinous carcinoma c.358A>G p.K120E 17:7676011-7676011 6
32 COSM87898605 TP53 ovary,NS,carcinoma,mucinous carcinoma c.824G>A p.C275Y 17:7673796-7673796 6
33 COSM87954987 TP53 ovary,NS,carcinoma,mucinous carcinoma c.592G>A p.E198K 17:7674939-7674939 6
34 COSM87898758 TP53 ovary,NS,carcinoma,mucinous carcinoma c.707A>G p.Y236C 17:7674256-7674256 6
35 COSM87905366 TP53 ovary,NS,carcinoma,adenocarcinoma c.476C>T p.A159V 17:7675136-7675136 6
36 COSM87899842 TP53 ovary,NS,carcinoma,mucinous carcinoma c.584T>C p.I195T 17:7674947-7674947 6
37 COSM87932556 TP53 ovary,NS,carcinoma,mucinous carcinoma c.434T>A p.L145Q 17:7675178-7675178 6
38 COSM87898392 TP53 ovary,NS,carcinoma,mucinous carcinoma c.713G>A p.C238Y 17:7674250-7674250 6
39 COSM87905748 TP53 ovary,NS,carcinoma,mucinous carcinoma c.404G>A p.C135Y 17:7675208-7675208 6
40 COSM87967965 TP53 ovary,NS,carcinoma,mucinous carcinoma c.580C>G p.L194V 17:7674951-7674951 6
41 COSM87897914 TP53 ovary,NS,carcinoma,mucinous carcinoma c.527G>T p.C176F 17:7675085-7675085 6
42 COSM87899497 TP53 ovary,NS,carcinoma,mucinous carcinoma c.586C>T p.R196* 17:7674945-7674945 6
43 COSM87943899 TP53 ovary,NS,carcinoma,mucinous carcinoma c.796G>C p.G266R 17:7673824-7673824 6
44 COSM87937910 TP53 ovary,NS,carcinoma,mucinous carcinoma c.772G>T p.E258* 17:7674191-7674191 6
45 COSM87898527 TP53 ovary,NS,carcinoma,mucinous carcinoma c.814G>A p.V272M 17:7673806-7673806 6
46 COSM87952110 TP53 ovary,NS,carcinoma,mucinous carcinoma c.755T>C p.L252P 17:7674208-7674208 6
47 COSM87901171 TP53 ovary,NS,carcinoma,adenocarcinoma c.395A>G p.K132R 17:7675217-7675217 6
48 COSM99344559 TNK2 ovary,NS,carcinoma,mucinous carcinoma c.485G>A p.R162Q 3:195884972-195884972 6
49 COSM145422024 TNFAIP3 ovary,NS,carcinoma,adenocarcinoma c.940G>A p.V314I 6:137877210-137877210 6
50 COSM86800549 TEX14 ovary,NS,carcinoma,mucinous carcinoma c.3501G>T p.K1167N 17:58574207-58574207 6

Expression for Ovarian Mucinous Adenocarcinoma

Search GEO for disease gene expression data for Ovarian Mucinous Adenocarcinoma.

Pathways for Ovarian Mucinous Adenocarcinoma

GO Terms for Ovarian Mucinous Adenocarcinoma

Biological processes related to Ovarian Mucinous Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 maintenance of gastrointestinal epithelium GO:0030277 8.62 SERPINA3 MUC2

Sources for Ovarian Mucinous Adenocarcinoma

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
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32 ICD10
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43 MeSH
44 MESH via Orphanet
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48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
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57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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