MCID: OVR054
MIFTS: 36

Ovarian Mucinous Neoplasm

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Mucinous Neoplasm

MalaCards integrated aliases for Ovarian Mucinous Neoplasm:

Name: Ovarian Mucinous Neoplasm 12 15
Ovarian Mucinous Tumor 12 74
Malignant Ovarian Mucinous Neoplasm 12
Malignant Ovarian Mucinous Tumor 74
Mucinous Tumor of Ovary 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6067
NCIt 51 C40033 C5242

Summaries for Ovarian Mucinous Neoplasm

Disease Ontology : 12 An ovary epithelial cancer that is characterized by the presence of mucin.

MalaCards based summary : Ovarian Mucinous Neoplasm, also known as ovarian mucinous tumor, is related to appendix adenocarcinoma and small cell carcinoma. An important gene associated with Ovarian Mucinous Neoplasm is CDX2 (Caudal Type Homeobox 2). The drugs Bevacizumab and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include ovary, kidney and appendix.

Related Diseases for Ovarian Mucinous Neoplasm

Diseases related to Ovarian Mucinous Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 214)
# Related Disease Score Top Affiliating Genes
1 appendix adenocarcinoma 30.4 CDX2 KRT20 KRT7
2 small cell carcinoma 30.4 ENO2 KRT20 KRT7 SYP
3 ovarian mucinous adenocarcinoma 30.4 CDX2 KRT20 KRT7
4 mucinous adenocarcinoma 30.4 CDX2 KRT20 KRT7
5 krukenberg carcinoma 30.2 KRT20 KRT7
6 cystadenoma 30.1 KRT20 KRT7 MUC6 SYP
7 pseudomyxoma peritonei 30.1 CDX2 KRT20 KRT7 MUC5AC MUC6
8 teratoma 30.1 CDX2 ENO2 KRT7 SYP
9 cystic teratoma 29.7 CDX2 ENO2 KRT20 KRT7 MUC6 SYP
10 ovarian mucinous malignant adenofibroma 11.3
11 nasal cavity cancer 10.6 CDX2 KRT7
12 nasal cavity adenocarcinoma 10.5 CDX2 KRT7
13 bladder lymphoma 10.5 KRT20 KRT7
14 papillary serous adenocarcinoma 10.5 KRT20 KRT7
15 linitis plastica 10.5 KRT20 KRT7
16 adenomyoma 10.5 KRT7 MUC6
17 bile duct adenoma 10.5 KRT20 KRT7
18 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
19 lung acinar adenocarcinoma 10.5 KRT20 KRT7
20 intratubular embryonal carcinoma 10.5 KRT20 KRT7
21 endocervical carcinoma 10.5 KRT7 MUC6
22 large cell acanthoma 10.5 KRT17 KRT7
23 morpheaform basal cell carcinoma 10.5 KRT17 KRT20
24 bowen's disease 10.5 KRT17 KRT7
25 endosalpingiosis 10.5 KRT7 WT1
26 renal adenoma 10.5 KRT7 WT1
27 female reproductive endometrioid cancer 10.5 KRT7 WT1
28 metanephric adenoma 10.5 KRT7 WT1
29 adenomatoid tumor 10.5 KRT7 WT1
30 seminal vesicle tumor 10.5 KRT7 SYP
31 pulmonary sclerosing hemangioma 10.5 KRT7 SYP
32 microcystic adenoma 10.5 ENO2 MUC6
33 goblet cell carcinoid 10.5 ENO2 KRT20
34 male reproductive organ benign neoplasm 10.5 SYP WT1
35 venous hemangioma 10.4 SYP WT1
36 ovarian small cell carcinoma 10.4 SYP WT1
37 kidney rhabdoid cancer 10.4 ENO2 WT1
38 epithelioid cell melanoma 10.4 ENO2 WT1
39 central nervous system primitive neuroectodermal neoplasm 10.4 ENO2 SYP
40 autonomic nervous system benign neoplasm 10.4 ENO2 SYP
41 melanotic neuroectodermal tumor 10.4 ENO2 SYP
42 vaginal benign neoplasm 10.4 CDX2 KRT20
43 extrahepatic bile duct adenocarcinoma 10.4 ENO2 SYP
44 cerebral ventricle cancer 10.4 ENO2 SYP
45 olfactory nerve neoplasm 10.4 ENO2 SYP
46 orbital cancer 10.4 ENO2 SYP
47 cerebral neuroblastoma 10.4 ENO2 SYP
48 cerebellum cancer 10.4 ENO2 SYP
49 extraosseous chondrosarcoma 10.4 ENO2 SYP
50 subependymal glioma 10.4 ENO2 SYP

Graphical network of the top 20 diseases related to Ovarian Mucinous Neoplasm:



Diseases related to Ovarian Mucinous Neoplasm

Symptoms & Phenotypes for Ovarian Mucinous Neoplasm

Drugs & Therapeutics for Ovarian Mucinous Neoplasm

Drugs for Ovarian Mucinous Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bevacizumab Approved, Investigational Phase 3 216974-75-3
2
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
3
Capecitabine Approved, Investigational Phase 3 154361-50-9 60953
4
Carboplatin Approved Phase 3 41575-94-4 10339178 38904 498142
5
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 43805 6857599 5310940 9887054
6 Antimetabolites Phase 3
7 Immunoglobulins Phase 3
8 Angiogenesis Modulating Agents Phase 3
9 Endothelial Growth Factors Phase 3
10 Antibodies, Monoclonal Phase 3
11 Antimitotic Agents Phase 3
12 Mitogens Phase 3
13 Immunoglobulin G Phase 3
14 Albumin-Bound Paclitaxel Phase 3
15 Antibodies Phase 3
16 Immunologic Factors Phase 3
17 Antineoplastic Agents, Phytogenic Phase 3
18 Angiogenesis Inhibitors Phase 3
19 Antineoplastic Agents, Immunological Phase 3
20 Antimetabolites, Antineoplastic Phase 3
21 CHI3L1 protein, human

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer Active, not recruiting NCT01081262 Phase 3 Capecitabine;Carboplatin;Oxaliplatin;Paclitaxel
2 Physical Activity Monitored by Fitbit Charge 2 in Improving Quality of Life in Participants With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Recruiting NCT03685695 Phase 2
3 YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Receiving Chemotherapy Terminated NCT00899093

Search NIH Clinical Center for Ovarian Mucinous Neoplasm

Genetic Tests for Ovarian Mucinous Neoplasm

Anatomical Context for Ovarian Mucinous Neoplasm

MalaCards organs/tissues related to Ovarian Mucinous Neoplasm:

42
Ovary, Kidney, Appendix, Endothelial, Prostate, Testis, Thymus

Publications for Ovarian Mucinous Neoplasm

Articles related to Ovarian Mucinous Neoplasm:

(show all 16)
# Title Authors Year
1
A case report of an incidental Brenner tumor found after resection of a large ovarian mucinous neoplasm. ( 29960208 )
2018
2
Clinicopathological Characteristics of Ovarian Metastasis from Colorectal and Pancreatobiliary Carcinomas Mimicking Primary Ovarian Mucinous Tumor. ( 30194204 )
2018
3
A Pyloric Gland-Phenotype Ovarian Mucinous Tumor Resembling Lobular Endocervical Glandular Hyperplasia in a Patient with Peutz-Jeghers Syndrome. ( 27550049 )
2017
4
Angiosarcoma Arising in Ovarian Mucinous Tumor: A Challenge in Intraoperative Frozen Section Diagnosis. ( 27872782 )
2016
5
Ovarian mucinous tumor with malignant mural nodules: dedifferentiation or collision? ( 25473748 )
2015
6
Trigeminal neuralgia as the first clinical manifestation of anti-hu paraneoplastic syndrome induced by a borderline ovarian mucinous tumor. ( 24575026 )
2014
7
Increased expression of OCIA domain containing 2 during stepwise progression of ovarian mucinous tumor. ( 22726067 )
2012
8
Borderline ovarian mucinous neoplasm recurring as small cell carcinoma of hypercalcemic type: evidence for an epithelial histogenesis and relationship with ovarian mucinous tumors for this enigmatic neoplasm. ( 21623206 )
2011
9
A huge ovarian mucinous cystadenoma in a 14-year-old premenarchal girl: review on ovarian mucinous tumor in premenarchal girls. ( 18312801 )
2008
10
Ovarian mucinous tumor arising in mature cystic teratoma associated with pseudomyxoma peritonei: a case with possible respiratory epithelial differentiation. ( 18156973 )
2008
11
Nuclear morphometry and AgNOR quantification: computerized image analysis on ovarian mucinous tumor imprints. ( 18630841 )
2008
12
Metastasis of small cell carcinoma of lung into an ovarian mucinous neoplasm: immunohistochemistry as a useful ancillary technique for diagnosis and classification of rare tumors. ( 15722802 )
2005
13
Anaplastic nodules in an ovarian mucinous tumor. Case report and literature review. ( 10215434 )
1998
14
Identical, unique p53 mutations in a primary ovarian mucinous adenocarcinoma and a synchronous contralateral ovarian mucinous tumor of low malignant potential suggest a common clonal origin. ( 9158713 )
1997
15
Fibrosarcoma arising in an ovarian mucinous tumor: a case report. ( 11578409 )
1994
16
Ovarian mucinous tumor with mural nodules of anaplastic carcinoma. ( 2477315 )
1989

Variations for Ovarian Mucinous Neoplasm

Expression for Ovarian Mucinous Neoplasm

Search GEO for disease gene expression data for Ovarian Mucinous Neoplasm.

Pathways for Ovarian Mucinous Neoplasm

GO Terms for Ovarian Mucinous Neoplasm

Cellular components related to Ovarian Mucinous Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 U2AF GO:0089701 8.62 U2AF1 U2AF1L4

Biological processes related to Ovarian Mucinous Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA splicing GO:0008380 9.56 SRSF2 U2AF1 U2AF1L4 WT1
2 cornification GO:0070268 9.54 KRT17 KRT20 KRT7
3 mRNA export from nucleus GO:0006406 9.5 SRSF2 U2AF1 U2AF1L4
4 intermediate filament organization GO:0045109 9.4 KRT17 KRT20
5 positive regulation of hair follicle development GO:0051798 9.16 FST KRT17
6 mRNA 3'-end processing GO:0031124 9.13 SRSF2 U2AF1 U2AF1L4
7 RNA export from nucleus GO:0006405 8.8 SRSF2 U2AF1 U2AF1L4

Molecular functions related to Ovarian Mucinous Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 pre-mRNA 3'-splice site binding GO:0030628 8.62 U2AF1 U2AF1L4

Sources for Ovarian Mucinous Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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