MCID: OVR056
MIFTS: 15

Ovarian Primitive Germ Cell Tumor

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Primitive Germ Cell Tumor

MalaCards integrated aliases for Ovarian Primitive Germ Cell Tumor:

Name: Ovarian Primitive Germ Cell Tumor 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:5351
NCIt 50 C39986
UMLS 72 C1518727

Summaries for Ovarian Primitive Germ Cell Tumor

Disease Ontology : 12 A malignant ovarian germ cell neoplasm that has material basis in primitive germ cells.

MalaCards based summary : Ovarian Primitive Germ Cell Tumor is related to teratoma and ovarian endodermal sinus tumor. An important gene associated with Ovarian Primitive Germ Cell Tumor is AFP (Alpha Fetoprotein). Related phenotype is homeostasis/metabolism.

Related Diseases for Ovarian Primitive Germ Cell Tumor

Diseases related to Ovarian Primitive Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 teratoma 30.3 KRT7 AFP
2 ovarian endodermal sinus tumor 29.9 SALL4 KRT7 HLX GPC3 AFP
3 endodermal sinus tumor 29.6 SALL4 GPC3 AFP
4 testicular yolk sac tumor 29.6 SALL4 GPC3 AFP
5 ovarian mixed germ cell neoplasm 11.6
6 polyembryoma of the ovary 11.6
7 non-gestational ovarian choriocarcinoma 11.6
8 intrahepatic bile duct adenoma 10.2 KRT7 AFP
9 testicular malignant germ cell cancer 10.2 GPC3 AFP
10 renal pelvis adenocarcinoma 10.2 KRT7 AFP
11 ovarian embryonal carcinoma 10.2 GPC3 AFP
12 intratubular embryonal carcinoma 10.2 KRT7 AFP
13 bile duct cystadenocarcinoma 10.2 KRT7 AFP
14 hepatic adenomas, familial 10.1 GPC3 AFP
15 adenomatoid tumor 10.1 KRT7 AFP
16 choriocarcinoma of the testis 10.1 KRT7 AFP
17 cystadenofibroma 10.1 KRT7 AFP
18 sertoli-leydig cell tumor 10.1 KRT7 AFP
19 mixed cell type cancer 10.1 KRT7 AFP
20 acinar cell carcinoma 10.1 KRT7 AFP
21 struma ovarii 10.1
22 germ cell and embryonal cancer 10.1 KRT7 AFP
23 malignant teratoma 10.1 SALL4 AFP
24 sex cord-gonadal stromal tumor 10.0 KRT7 AFP
25 extragonadal seminoma 10.0 SALL4 AFP
26 epithelioid trophoblastic tumor 10.0 SALL4 KRT7
27 dysgerminoma 10.0 KRT7 AFP
28 bile duct disease 10.0 KRT7 AFP
29 ovarian clear cell carcinoma 10.0 KRT7 GPC3
30 biliary tract disease 10.0 KRT7 AFP
31 testicular germ cell tumor 9.9 GPC3 AFP
32 epithelioid sarcoma 9.9 SALL4 KRT7
33 ovarian brenner tumor 9.9 SALL4 KRT7
34 intrahepatic cholangiocarcinoma 9.9 KRT7 AFP
35 endocrine gland cancer 9.8 GPC3 AFP
36 beckwith-wiedemann syndrome 9.7 GPC3 AFP
37 seminal vesicle tumor 9.7 KRT7 GPC3 AFP
38 bile duct adenocarcinoma 9.7 KRT7 GPC3 AFP
39 hepatoblastoma 9.7 KRT7 GPC3 AFP
40 gastrointestinal system cancer 9.7 KRT7 GPC3 AFP
41 cholangiocarcinoma 9.7 KRT7 GPC3 AFP
42 embryoma 9.6 SALL4 GPC3 AFP
43 liver cirrhosis 9.5 GPC3 AFP
44 ovarian germ cell cancer 8.9 SALL4 KRT7 HLX AFP

Graphical network of the top 20 diseases related to Ovarian Primitive Germ Cell Tumor:



Diseases related to Ovarian Primitive Germ Cell Tumor

Symptoms & Phenotypes for Ovarian Primitive Germ Cell Tumor

MGI Mouse Phenotypes related to Ovarian Primitive Germ Cell Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.02 AFP GPC3 HLX KRT7 SALL4

Drugs & Therapeutics for Ovarian Primitive Germ Cell Tumor

Search Clinical Trials , NIH Clinical Center for Ovarian Primitive Germ Cell Tumor

Genetic Tests for Ovarian Primitive Germ Cell Tumor

Anatomical Context for Ovarian Primitive Germ Cell Tumor

Publications for Ovarian Primitive Germ Cell Tumor

Variations for Ovarian Primitive Germ Cell Tumor

Expression for Ovarian Primitive Germ Cell Tumor

Search GEO for disease gene expression data for Ovarian Primitive Germ Cell Tumor.

Pathways for Ovarian Primitive Germ Cell Tumor

GO Terms for Ovarian Primitive Germ Cell Tumor

Sources for Ovarian Primitive Germ Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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