MCID: OVR002
MIFTS: 29

Ovarian Serous Cystadenofibroma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases
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Aliases & Classifications for Ovarian Serous Cystadenofibroma

MalaCards integrated aliases for Ovarian Serous Cystadenofibroma:

Name: Ovarian Serous Cystadenofibroma 11 14 71

Classifications:



External Ids:

Disease Ontology 11 DOID:7320
NCIt 49 C40032
UMLS 71 C0877572

Summaries for Ovarian Serous Cystadenofibroma

Disease Ontology: 11 An ovarian serous adenofibroma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary: Ovarian Serous Cystadenofibroma is related to ovarian serous cystadenocarcinoma and cystadenofibroma, and has symptoms including abdominal pain An important gene associated with Ovarian Serous Cystadenofibroma is CALB2 (Calbindin 2), and among its related pathways/superpathways are Breast cancer pathway and Thyroid hormones production and peripheral downstream signaling effects. Related phenotypes are Decreased viability in pancreas lineage and normal

Related Diseases for Ovarian Serous Cystadenofibroma

Diseases related to Ovarian Serous Cystadenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 364)
# Related Disease Score Top Affiliating Genes
1 ovarian serous cystadenocarcinoma 30.2 TP53 PAX8 BRCA1
2 cystadenofibroma 30.1 WT1 TP53 PAX8 KRT7 CALB2
3 cystadenoma 29.9 PGR KRT7 CALB2 BRCA1
4 papillary carcinoma 29.7 TG PAX8 KRT7 CALB2
5 serous cystadenocarcinoma 28.7 WT1 TP53 PGR PAX8 KRT7 CALB2
6 neurohypophysis granular cell tumor 10.3 NCAM1 CALB2
7 infected hydrocele 10.3 NCAM1 CALB2
8 clear cell cystadenofibroma 10.3 TP53 CALB2
9 wolffian duct adenocarcinoma 10.3 PAX8 CALB2
10 large cell carcinoma with rhabdoid phenotype 10.3 TP53 CALB2
11 lymphohistiocytoid mesothelioma 10.2 PAX8 CALB2
12 tuberculous epididymitis 10.2 CALB2 AMH
13 fallopian tube endometrioid adenocarcinoma 10.2 PAX8 CALB2
14 malignant epithelial mesothelioma 10.2 KRT7 CALB2
15 thyroid dyshormonogenesis 1 10.2 SLC5A5 PAX8
16 peritoneal benign neoplasm 10.2 PGR CALB2
17 ovarian mucinous cystadenofibroma 10.2 NCAM1 KRT7
18 ovarian mucinous adenofibroma 10.2 NCAM1 KRT7
19 mucinous adenofibroma 10.2 NCAM1 KRT7
20 liver leiomyoma 10.2 PGR CALB2
21 pancreatic mucinous cystadenoma 10.2 PGR CALB2
22 prostatic urethral cancer 10.2 NCAM1 KRT7
23 middle ear adenoma 10.2 NCAM1 KRT7
24 auditory system benign neoplasm 10.2 NCAM1 KRT7
25 urinary bladder small cell neuroendocrine carcinoma 10.2 NCAM1 KRT7
26 luteoma 10.2 CALB2 AMH
27 ureter small cell carcinoma 10.2 NCAM1 KRT7
28 bilateral hypoactive labyrinth 10.2 NCAM1 KRT7
29 biphasic synovial sarcoma 10.2 KRT7 CALB2
30 sensory organ benign neoplasm 10.2 NCAM1 KRT7
31 cholangiolocellular carcinoma 10.2 NCAM1 KRT7
32 medullary colon carcinoma 10.2 KRT7 CALB2
33 middle ear carcinoma 10.2 TG CALB2
34 sinonasal undifferentiated carcinoma 10.2 NCAM1 KRT7
35 transitional meningioma 10.2 PGR NCAM1
36 mullerian aplasia and hyperandrogenism 10.2 WNT4 HOXA7
37 prostate stromal sarcoma 10.2 PGR NCAM1
38 bartholin's gland adenoma 10.2 TP53 PGR
39 bartholin's gland benign neoplasm 10.2 TP53 PGR
40 vestibular gland benign neoplasm 10.2 TP53 PGR
41 vulvar leiomyoma 10.2 PGR NCAM1
42 adenosquamous breast carcinoma 10.2 TP53 PGR
43 nephrogenic adenoma 10.2 PAX8 KRT7
44 keratinizing squamous cell carcinoma 10.2 TP53 KRT7
45 prostate neuroendocrine neoplasm 10.2 NCAM1 KRT7
46 solid adenocarcinoma with mucin production 10.2 NCAM1 KRT7
47 pancreatic foamy gland adenocarcinoma 10.1 TP53 KRT7
48 periampullary adenocarcinoma 10.1 NCAM1 KRT7
49 chronic salpingitis 10.1 PAX8 AMH
50 malignant spiradenoma 10.1 TP53 KRT7

Graphical network of the top 20 diseases related to Ovarian Serous Cystadenofibroma:



Diseases related to Ovarian Serous Cystadenofibroma

Symptoms & Phenotypes for Ovarian Serous Cystadenofibroma

UMLS symptoms related to Ovarian Serous Cystadenofibroma:


abdominal pain

GenomeRNAi Phenotypes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in pancreas lineage GR00235-A 8.92 AMH KRT7 PGR TP53

MGI Mouse Phenotypes related to Ovarian Serous Cystadenofibroma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 10.03 BRCA1 CALB2 HOXA7 PAX8 PGR TP53
2 endocrine/exocrine gland MP:0005379 10.03 AMH BRCA1 HOXA7 HOXA9 HOXD9 PAX8
3 renal/urinary system MP:0005367 9.97 BRCA1 HOXD9 KRT7 PAX8 SLC5A5 TP53
4 limbs/digits/tail MP:0005371 9.92 BRCA1 HOXA9 HOXD9 PAX8 PGR TG
5 no phenotypic analysis MP:0003012 9.88 AMH PAX8 PGR TP53 WNT4 WT1
6 cellular MP:0005384 9.85 BRCA1 HOXD9 KRT7 NCAM1 PAX8 PGR
7 reproductive system MP:0005389 9.65 AMH BRCA1 HOXA9 HOXD9 PAX8 PGR
8 skeleton MP:0005390 9.32 BRCA1 HOXA7 HOXA9 HOXD9 PAX8 PGR

Drugs & Therapeutics for Ovarian Serous Cystadenofibroma

Search Clinical Trials, NIH Clinical Center for Ovarian Serous Cystadenofibroma

Genetic Tests for Ovarian Serous Cystadenofibroma

Anatomical Context for Ovarian Serous Cystadenofibroma

Publications for Ovarian Serous Cystadenofibroma

Articles related to Ovarian Serous Cystadenofibroma:

(show all 16)
# Title Authors PMID Year
1
Ovarian remnant syndrome with paraintestinal ovarian serous cystadenofibroma arose 30 years after bilateral salpingo-oophorectomy: A case report. 62
36343074 2022
2
A case of ovarian serous cystadenofibroma with scattered lesions in pelvic cavity, like malignant disseminations. 62
34490687 2021
3
A ruptured ovarian cystadenofibroma presenting with life-threatening sepsis and an incidental synchronous endometrial stromal sarcoma. 62
34844964 2021
4
Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma. 62
33553558 2021
5
Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report. 62
33045892 2020
6
Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases. 62
32376242 2020
7
Serous Tubal Intraepithelial Carcinoma (STIC)-like Lesions Arising in Ovarian Serous Cystadenofibroma: Report of 2 Cases. 62
26107558 2015
8
An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. 62
24791367 2014
9
False-positive I-131 uptake by an ovarian serous cystadenofibroma. 62
22228346 2012
10
Ovarian serous cystadenofibroma with signet ring-stromal cells: report of 2 cases. 62
20736763 2010
11
Extensive pelvic calcification in association with ovarian serous cystadenofibroma. 62
18840187 2008
12
Ovarian serous cystadenofibroma with stromal sex cord elements: report of a unique case. 62
16990708 2006
13
Eosinophilic hyperplasia of fallopian tube mucosa. 62
9798416 1998
14
Longstanding ovarian serous cystadenofibroma sonographically mimicking a urachal cyst. 62
8822669 1996
15
Ovarian serous cystadenofibroma of borderline malignancy: report of two cases. 62
7372194 1980
16
The ovarian serous cystadenofibroma; a report of 25 cases. 62
13649808 1959

Variations for Ovarian Serous Cystadenofibroma

Expression for Ovarian Serous Cystadenofibroma

Search GEO for disease gene expression data for Ovarian Serous Cystadenofibroma.

Pathways for Ovarian Serous Cystadenofibroma

GO Terms for Ovarian Serous Cystadenofibroma

Biological processes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 regulation of DNA-templated transcription GO:0006355 10.16 WT1 TP53 PGR PAX8 HOXD9 HOXA9
2 positive regulation of transcription by RNA polymerase II GO:0045944 10.16 WT1 TP53 PGR PAX8 HOXD9 HOXA9
3 embryonic skeletal system morphogenesis GO:0048704 9.95 HOXD9 HOXA9 HOXA7
4 branching involved in ureteric bud morphogenesis GO:0001658 9.85 PAX8 WNT4 WT1
5 mesenchymal to epithelial transition GO:0060231 9.83 WT1 WNT4
6 sex determination GO:0007530 9.8 WT1 AMH
7 metanephric S-shaped body morphogenesis GO:0072284 9.76 WT1 PAX8
8 metanephric epithelium development GO:0072207 9.73 WT1 PAX8
9 iodide transport GO:0015705 9.71 TG SLC5A5
10 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 9.46 WNT4 PGR
11 mammary gland development GO:0030879 9.35 PGR HOXD9 HOXA9
12 mesonephric tubule development GO:0072164 9.32 WNT4 PAX8
13 cellular response to gonadotropin stimulus GO:0071371 9.1 WT1 SLC5A5 PAX8

Molecular functions related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 9.73 WT1 TP53 PGR PAX8 HOXA9 HOXA7
2 DNA-binding transcription factor activity GO:0003700 9.4 WT1 TP53 PGR PAX8 HOXD9 HOXA9

Sources for Ovarian Serous Cystadenofibroma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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