Ovarian Serous Cystadenofibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Ovarian Serous Cystadenofibroma

MalaCards integrated aliases for Ovarian Serous Cystadenofibroma:

Name: Ovarian Serous Cystadenofibroma ¹² ¹⁵ ⁷⁰

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7320

NCIt ⁵⁰ C40032

UMLS ⁷⁰ C0877572

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Summaries for Ovarian Serous Cystadenofibroma

Disease Ontology : ¹² An ovarian serous adenofibroma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary : Ovarian Serous Cystadenofibroma is related to cystadenofibroma and papillary carcinoma, and has symptoms including abdominal pain An important gene associated with Ovarian Serous Cystadenofibroma is CALB2 (Calbindin 2), and among its related pathways/superpathways are DNA Damage Induced 14-3-3Sigma Signaling and Thyroxine (Thyroid Hormone) Production. Affiliated tissues include lung, breast and thyroid, and related phenotypes are endocrine/exocrine gland and limbs/digits/tail

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Related Diseases for Ovarian Serous Cystadenofibroma

Diseases related to Ovarian Serous Cystadenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 244)

#	Related Disease	Score	Top Affiliating Genes
1	cystadenofibroma	30.2	TP53 MUC1 KRT7 INHA CALB2
2	papillary carcinoma	29.8	TG MUC1 KRT7 CALB2
3	clear cell adenofibroma	10.6
4	spindle cell thymoma	10.4	MUC1 CALB2
5	lung sarcomatoid carcinoma	10.4	MUC1 CALB2
6	rete testis adenoma	10.4	NCAM1 CALB2
7	adult type testicular granulosa cell tumor	10.4	NCAM1 CALB2
8	pericardial mesothelioma	10.4	MUC1 CALB2
9	infected hydrocele	10.3	NCAM1 CALB2
10	esophageal neuroendocrine tumor	10.3	NCAM1 MUC1
11	fallopian tube adenocarcinoma	10.3	CALB2 BRCA1
12	chordoid meningioma	10.3	NCAM1 MUC1
13	transitional meningioma	10.3	NCAM1 MUC1
14	ovarian gonadoblastoma	10.3	WNT4 CALB2
15	ovarian small cell carcinoma	10.3	MUC1 INHA CALB2
16	microcystic adenoma	10.3	MUC1 INHA
17	rete testis neoplasm	10.2	KRT7 CALB2
18	rete testis adenocarcinoma	10.2	KRT7 CALB2
19	bartholin's gland disease	10.2	KRT7 CALB2
20	scrotum paget's disease	10.2	MUC1 KRT7
21	dermoid cyst of ovary	10.2	CALB2 AMH
22	gallbladder signet ring cell adenocarcinoma	10.2	MUC1 KRT7
23	epididymal neoplasm	10.2	KRT7 CALB2
24	urinary bladder villous adenoma	10.2	MUC1 KRT7
25	wolffian duct adenocarcinoma	10.2	KRT7 CALB2
26	pericardium cancer	10.2	KRT7 CALB2
27	mucinous intrahepatic cholangiocarcinoma	10.2	MUC1 KRT7
28	middle ear adenoma	10.2	MUC1 KRT7
29	uterus perivascular epithelioid cell tumor	10.2	KRT7 CALB2
30	bile duct cystadenocarcinoma	10.2	MUC1 KRT7
31	colonic lymphangioma	10.2	MUC1 KRT7
32	nephrogenic adenoma of the urethra	10.2	KRT7 CALB2
33	mucinous stomach adenocarcinoma	10.2	KRT7 CALB2
34	biliary papillomatosis	10.2	MUC1 KRT7
35	bile duct mucoepidermoid carcinoma	10.2	MUC1 KRT7
36	lipoadenoma	10.2	MUC1 KRT7
37	parachordoma	10.2	MUC1 KRT7
38	nephrogenic adenoma	10.2	MUC1 KRT7
39	thymus clear cell carcinoma	10.2	KRT7 CALB2
40	pancreatic serous cystadenocarcinoma	10.2	NCAM1 KRT7
41	liver leiomyosarcoma	10.2	KRT7 CALB2
42	lung leiomyosarcoma	10.2	KRT7 CALB2
43	gallbladder small cell carcinoma	10.2	NCAM1 KRT7
44	mucinous tubular and spindle renal cell carcinoma	10.2	MUC1 KRT7
45	ureter small cell carcinoma	10.2	NCAM1 KRT7
46	ovarian sex-cord stromal tumor	10.2	KRT7 CALB2
47	urinary bladder small cell neuroendocrine carcinoma	10.2	NCAM1 KRT7
48	sensory organ benign neoplasm	10.2	NCAM1 KRT7
49	epididymis adenocarcinoma	10.2	KRT7 CALB2
50	epididymis cancer	10.2	KRT7 CALB2

Graphical network of the top 20 diseases related to Ovarian Serous Cystadenofibroma:

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Symptoms & Phenotypes for Ovarian Serous Cystadenofibroma

UMLS symptoms related to Ovarian Serous Cystadenofibroma:

abdominal pain

MGI Mouse Phenotypes related to Ovarian Serous Cystadenofibroma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.96	AMH BRCA1 HOXA7 HOXA9 HOXD9 INHA
2	limbs/digits/tail	MP:0005371	9.63	BRCA1 HOXA9 HOXD9 TG TP53 WNT4
3	reproductive system	MP:0005389	9.56	AMH BRCA1 HOXA9 HOXD9 INHA TG
4	skeleton	MP:0005390	9.28	BRCA1 HOXA7 HOXA9 HOXD9 INHA SLC5A5

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Drugs & Therapeutics for Ovarian Serous Cystadenofibroma

Search Clinical Trials , NIH Clinical Center for Ovarian Serous Cystadenofibroma

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Genetic Tests for Ovarian Serous Cystadenofibroma

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Anatomical Context for Ovarian Serous Cystadenofibroma

MalaCards organs/tissues related to Ovarian Serous Cystadenofibroma:

⁴⁰

Lung, Breast, Thyroid, Ovary, Testis, Kidney, Liver

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Publications for Ovarian Serous Cystadenofibroma

Articles related to Ovarian Serous Cystadenofibroma:

(show all 13)

#	Title	Authors	PMID	Year
1	Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma. ⁶¹	Ribeiro E Ribeiro R...Quddus MR	33553558	2021
2	Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report. ⁶¹	Yang S...Yang L	33045892	2020
3	Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases. ⁶¹	Ersoy E...Kashikar RM	32376242	2020
4	Serous Tubal Intraepithelial Carcinoma (STIC)-like Lesions Arising in Ovarian Serous Cystadenofibroma: Report of 2 Cases. ⁶¹	Craig E...McCluggage WG	26107558	2015
5	An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. ⁶¹	Cruz-Galarza D...Gutierrez-Rivera S	24791367	2014
6	False-positive I-131 uptake by an ovarian serous cystadenofibroma. ⁶¹	Flug J...Yung E	22228346	2012
7	Ovarian serous cystadenofibroma with signet ring-stromal cells: report of 2 cases. ⁶¹	Shah R...McCluggage WG	20736763	2010
8	Extensive pelvic calcification in association with ovarian serous cystadenofibroma. ⁶¹	Hayes SJ...Wilson G	18840187	2008
9	Ovarian serous cystadenofibroma with stromal sex cord elements: report of a unique case. ⁶¹	Dillon K...McCluggage WG	16990708	2006
10	Eosinophilic hyperplasia of fallopian tube mucosa. ⁶¹	Rabczynski J...Ratajczak S	9798416	1998
11	Longstanding ovarian serous cystadenofibroma sonographically mimicking a urachal cyst. ⁶¹	Abulafia O...Sherer D	8822669	1996
12	Ovarian serous cystadenofibroma of borderline malignancy: report of two cases. ⁶¹	Honore LH	7372194	1980
13	The ovarian serous cystadenofibroma; a report of 25 cases. ⁶¹	McNULTY JR	13649808	1959

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Genes for Ovarian Serous Cystadenofibroma

Genes related to Ovarian Serous Cystadenofibroma (0 elite genes):

(show all 14)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CALB2	Calbindin 2	Protein Coding	13.28	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	INHA	Inhibin Subunit Alpha	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
3	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	7.13	GeneCards inferred via : Publications (show sections)
4	HOXD9	Homeobox D9	Protein Coding	5.33	DISEASES inferred ¹⁵
5	HOXA7	Homeobox A7	Protein Coding	4.81	DISEASES inferred ¹⁵
6	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	4.55	DISEASES inferred ¹⁵
7	SLC5A5	Solute Carrier Family 5 Member 5	Protein Coding	4.51	DISEASES inferred ¹⁵
8	WNT4	Wnt Family Member 4	Protein Coding	4.24	DISEASES inferred ¹⁵
9	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	4.23	DISEASES inferred ¹⁵
10	HOXA9	Homeobox A9	Protein Coding	4.2	DISEASES inferred ¹⁵
11	AMH	Anti-Mullerian Hormone	Protein Coding	3.97	DISEASES inferred ¹⁵
12	TG	Thyroglobulin	Protein Coding	3.51	DISEASES inferred ¹⁵
13	TP53	Tumor Protein P53	Protein Coding	3.49	DISEASES inferred ¹⁵
14	KRT7	Keratin 7	Protein Coding	3.48	DISEASES inferred ¹⁵

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Variations for Ovarian Serous Cystadenofibroma

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Expression for Ovarian Serous Cystadenofibroma

Search GEO for disease gene expression data for Ovarian Serous Cystadenofibroma.

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Pathways for Ovarian Serous Cystadenofibroma

Pathways related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	DNA Damage Induced 14-3-3Sigma Signaling ⁶³	10.23	TP53 BRCA1
2	Thyroxine (Thyroid Hormone) Production ¹	9.4	TG SLC5A5

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GO Terms for Ovarian Serous Cystadenofibroma

Biological processes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	male gonad development	GO:0008584	9.54	WNT4 INHA HOXA9
2	anterior/posterior pattern specification	GO:0009952	9.5	HOXD9 HOXA9 HOXA7
3	negative regulation of reactive oxygen species metabolic process	GO:2000378	9.43	TP53 BRCA1
4	thyroid hormone generation	GO:0006590	9.4	TG SLC5A5
5	embryonic skeletal system morphogenesis	GO:0048704	9.33	HOXD9 HOXA9 HOXA7
6	positive regulation of transcription from RNA polymerase II promoter in response to stress	GO:0036003	9.26	TP53 MUC1
7	iodide transport	GO:0015705	8.96	TG SLC5A5
8	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	GO:0006978	8.8	TP53 MUC1 BRCA1

Molecular functions related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	8.8	TG INHA AMH

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