Ovarian Serous Cystadenofibroma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Ovarian Serous Cystadenofibroma

MalaCards integrated aliases for Ovarian Serous Cystadenofibroma:

Name: Ovarian Serous Cystadenofibroma ¹¹ ¹⁴ ⁷¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:7320

NCIt ⁴⁹ C40032

UMLS ⁷¹ C0877572

Sources

Summaries for Ovarian Serous Cystadenofibroma

Disease Ontology: ¹¹ An ovarian serous adenofibroma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary: Ovarian Serous Cystadenofibroma is related to ovarian serous cystadenocarcinoma and cystadenofibroma, and has symptoms including abdominal pain An important gene associated with Ovarian Serous Cystadenofibroma is CALB2 (Calbindin 2), and among its related pathways/superpathways are Breast cancer pathway and Thyroid hormones production and peripheral downstream signaling effects. Related phenotypes are Decreased viability in pancreas lineage and normal

Sources

Related Diseases for Ovarian Serous Cystadenofibroma

Diseases related to Ovarian Serous Cystadenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 364)

#	Related Disease	Score	Top Affiliating Genes
1	ovarian serous cystadenocarcinoma	30.2	TP53 PAX8 BRCA1
2	cystadenofibroma	30.1	WT1 TP53 PAX8 KRT7 CALB2
3	cystadenoma	29.9	PGR KRT7 CALB2 BRCA1
4	papillary carcinoma	29.7	TG PAX8 KRT7 CALB2
5	serous cystadenocarcinoma	28.7	WT1 TP53 PGR PAX8 KRT7 CALB2
6	neurohypophysis granular cell tumor	10.3	NCAM1 CALB2
7	infected hydrocele	10.3	NCAM1 CALB2
8	clear cell cystadenofibroma	10.3	TP53 CALB2
9	wolffian duct adenocarcinoma	10.3	PAX8 CALB2
10	large cell carcinoma with rhabdoid phenotype	10.3	TP53 CALB2
11	lymphohistiocytoid mesothelioma	10.2	PAX8 CALB2
12	tuberculous epididymitis	10.2	CALB2 AMH
13	fallopian tube endometrioid adenocarcinoma	10.2	PAX8 CALB2
14	malignant epithelial mesothelioma	10.2	KRT7 CALB2
15	thyroid dyshormonogenesis 1	10.2	SLC5A5 PAX8
16	peritoneal benign neoplasm	10.2	PGR CALB2
17	ovarian mucinous cystadenofibroma	10.2	NCAM1 KRT7
18	ovarian mucinous adenofibroma	10.2	NCAM1 KRT7
19	mucinous adenofibroma	10.2	NCAM1 KRT7
20	liver leiomyoma	10.2	PGR CALB2
21	pancreatic mucinous cystadenoma	10.2	PGR CALB2
22	prostatic urethral cancer	10.2	NCAM1 KRT7
23	middle ear adenoma	10.2	NCAM1 KRT7
24	auditory system benign neoplasm	10.2	NCAM1 KRT7
25	urinary bladder small cell neuroendocrine carcinoma	10.2	NCAM1 KRT7
26	luteoma	10.2	CALB2 AMH
27	ureter small cell carcinoma	10.2	NCAM1 KRT7
28	bilateral hypoactive labyrinth	10.2	NCAM1 KRT7
29	biphasic synovial sarcoma	10.2	KRT7 CALB2
30	sensory organ benign neoplasm	10.2	NCAM1 KRT7
31	cholangiolocellular carcinoma	10.2	NCAM1 KRT7
32	medullary colon carcinoma	10.2	KRT7 CALB2
33	middle ear carcinoma	10.2	TG CALB2
34	sinonasal undifferentiated carcinoma	10.2	NCAM1 KRT7
35	transitional meningioma	10.2	PGR NCAM1
36	mullerian aplasia and hyperandrogenism	10.2	WNT4 HOXA7
37	prostate stromal sarcoma	10.2	PGR NCAM1
38	bartholin's gland adenoma	10.2	TP53 PGR
39	bartholin's gland benign neoplasm	10.2	TP53 PGR
40	vestibular gland benign neoplasm	10.2	TP53 PGR
41	vulvar leiomyoma	10.2	PGR NCAM1
42	adenosquamous breast carcinoma	10.2	TP53 PGR
43	nephrogenic adenoma	10.2	PAX8 KRT7
44	keratinizing squamous cell carcinoma	10.2	TP53 KRT7
45	prostate neuroendocrine neoplasm	10.2	NCAM1 KRT7
46	solid adenocarcinoma with mucin production	10.2	NCAM1 KRT7
47	pancreatic foamy gland adenocarcinoma	10.1	TP53 KRT7
48	periampullary adenocarcinoma	10.1	NCAM1 KRT7
49	chronic salpingitis	10.1	PAX8 AMH
50	malignant spiradenoma	10.1	TP53 KRT7

Graphical network of the top 20 diseases related to Ovarian Serous Cystadenofibroma:

Sources

Symptoms & Phenotypes for Ovarian Serous Cystadenofibroma

UMLS symptoms related to Ovarian Serous Cystadenofibroma:

abdominal pain

GenomeRNAi Phenotypes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

²⁵

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased viability in pancreas lineage	GR00235-A	8.92	AMH KRT7 PGR TP53

MGI Mouse Phenotypes related to Ovarian Serous Cystadenofibroma:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	normal	MP:0002873	10.03	BRCA1 CALB2 HOXA7 PAX8 PGR TP53
2	endocrine/exocrine gland	MP:0005379	10.03	AMH BRCA1 HOXA7 HOXA9 HOXD9 PAX8
3	renal/urinary system	MP:0005367	9.97	BRCA1 HOXD9 KRT7 PAX8 SLC5A5 TP53
4	limbs/digits/tail	MP:0005371	9.92	BRCA1 HOXA9 HOXD9 PAX8 PGR TG
5	no phenotypic analysis	MP:0003012	9.88	AMH PAX8 PGR TP53 WNT4 WT1
6	cellular	MP:0005384	9.85	BRCA1 HOXD9 KRT7 NCAM1 PAX8 PGR
7	reproductive system	MP:0005389	9.65	AMH BRCA1 HOXA9 HOXD9 PAX8 PGR
8	skeleton	MP:0005390	9.32	BRCA1 HOXA7 HOXA9 HOXD9 PAX8 PGR

Sources

Drugs & Therapeutics for Ovarian Serous Cystadenofibroma

Search Clinical Trials, NIH Clinical Center for Ovarian Serous Cystadenofibroma

Sources

Genetic Tests for Ovarian Serous Cystadenofibroma

Sources

Anatomical Context for Ovarian Serous Cystadenofibroma

Sources

Publications for Ovarian Serous Cystadenofibroma

Articles related to Ovarian Serous Cystadenofibroma:

(show all 16)

#	Title	Authors	PMID	Year
1	Ovarian remnant syndrome with paraintestinal ovarian serous cystadenofibroma arose 30 years after bilateral salpingo-oophorectomy: A case report. ⁶²	Tien CT...Ding DC	36343074	2022
2	A case of ovarian serous cystadenofibroma with scattered lesions in pelvic cavity, like malignant disseminations. ⁶²	Fujita K...Shibata K	34490687	2021
3	A ruptured ovarian cystadenofibroma presenting with life-threatening sepsis and an incidental synchronous endometrial stromal sarcoma. ⁶²	Boyd A...Aziz M	34844964	2021
4	Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma. ⁶²	Ribeiro E Ribeiro R...Quddus MR	33553558	2021
5	Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report. ⁶²	Yang S...Yang L	33045892	2020
6	Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases. ⁶²	Ersoy E...Kashikar RM	32376242	2020
7	Serous Tubal Intraepithelial Carcinoma (STIC)-like Lesions Arising in Ovarian Serous Cystadenofibroma: Report of 2 Cases. ⁶²	Craig E...McCluggage WG	26107558	2015
8	An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. ⁶²	Cruz-Galarza D...Gutierrez-Rivera S	24791367	2014
9	False-positive I-131 uptake by an ovarian serous cystadenofibroma. ⁶²	Flug J...Yung E	22228346	2012
10	Ovarian serous cystadenofibroma with signet ring-stromal cells: report of 2 cases. ⁶²	Shah R...McCluggage WG	20736763	2010
11	Extensive pelvic calcification in association with ovarian serous cystadenofibroma. ⁶²	Hayes SJ...Wilson G	18840187	2008
12	Ovarian serous cystadenofibroma with stromal sex cord elements: report of a unique case. ⁶²	Dillon K...McCluggage WG	16990708	2006
13	Eosinophilic hyperplasia of fallopian tube mucosa. ⁶²	Rabczynski J...Ratajczak S	9798416	1998
14	Longstanding ovarian serous cystadenofibroma sonographically mimicking a urachal cyst. ⁶²	Abulafia O...Sherer D	8822669	1996
15	Ovarian serous cystadenofibroma of borderline malignancy: report of two cases. ⁶²	Honore LH	7372194	1980
16	The ovarian serous cystadenofibroma; a report of 25 cases. ⁶²	McNULTY JR	13649808	1959

Sources

Genes for Ovarian Serous Cystadenofibroma

Genes related to Ovarian Serous Cystadenofibroma (0 elite genes):

(show all 15)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CALB2	Calbindin 2	Protein Coding	5.58	DISEASES inferred ¹⁴
2	HOXD9	Homeobox D9	Protein Coding	4.64	DISEASES inferred ¹⁴
3	HOXA7	Homeobox A7	Protein Coding	4.16	DISEASES inferred ¹⁴
4	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	3.88	DISEASES inferred ¹⁴
5	SLC5A5	Solute Carrier Family 5 Member 5	Protein Coding	3.87	DISEASES inferred ¹⁴
6	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	3.58	DISEASES inferred ¹⁴
7	WNT4	Wnt Family Member 4	Protein Coding	3.56	DISEASES inferred ¹⁴
8	HOXA9	Homeobox A9	Protein Coding	3.52	DISEASES inferred ¹⁴
9	TP53	Tumor Protein P53	Protein Coding	3.45	DISEASES inferred ¹⁴
10	PAX8	Paired Box 8	Protein Coding	3.29	DISEASES inferred ¹⁴
11	AMH	Anti-Mullerian Hormone	Protein Coding	3.24	DISEASES inferred ¹⁴
12	PGR	Progesterone Receptor	Protein Coding	3.22	DISEASES inferred ¹⁴
13	TG	Thyroglobulin	Protein Coding	2.87	DISEASES inferred ¹⁴
14	WT1	WT1 Transcription Factor	Protein Coding	2.82	DISEASES inferred ¹⁴
15	KRT7	Keratin 7	Protein Coding	2.8	DISEASES inferred ¹⁴

Sources

Variations for Ovarian Serous Cystadenofibroma

Sources

Expression for Ovarian Serous Cystadenofibroma

Search GEO for disease gene expression data for Ovarian Serous Cystadenofibroma.

Sources

Pathways for Ovarian Serous Cystadenofibroma

Pathways related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Breast cancer pathway ⁷⁴ Show member pathways Embryonic stem cell pluripotency pathways ⁷⁴	11.69	WNT4 TP53 PGR BRCA1
2	Thyroid hormones production and peripheral downstream signaling effects ⁷⁴	11.25	WNT4 TP53 SLC5A5
3	Thyroxine (thyroid hormone) production ⁷⁴	10.62	TG SLC5A5
4	DNA Damage Induced 14-3-3Sigma Signaling ⁶⁴	10.54	TP53 BRCA1
5	Mammalian disorder of sexual development ⁷⁴ Show member pathways Somatic sex determination ⁷⁴ Transcriptional regulation of testis differentiation ⁶⁶	10.49	WT1 WNT4 AMH

Sources

GO Terms for Ovarian Serous Cystadenofibroma

Biological processes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

(show all 13)

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of DNA-templated transcription	GO:0006355	10.16	WT1 TP53 PGR PAX8 HOXD9 HOXA9
2	positive regulation of transcription by RNA polymerase II	GO:0045944	10.16	WT1 TP53 PGR PAX8 HOXD9 HOXA9
3	embryonic skeletal system morphogenesis	GO:0048704	9.95	HOXD9 HOXA9 HOXA7
4	branching involved in ureteric bud morphogenesis	GO:0001658	9.85	PAX8 WNT4 WT1
5	mesenchymal to epithelial transition	GO:0060231	9.83	WT1 WNT4
6	sex determination	GO:0007530	9.8	WT1 AMH
7	metanephric S-shaped body morphogenesis	GO:0072284	9.76	WT1 PAX8
8	metanephric epithelium development	GO:0072207	9.73	WT1 PAX8
9	iodide transport	GO:0015705	9.71	TG SLC5A5
10	tertiary branching involved in mammary gland duct morphogenesis	GO:0060748	9.46	WNT4 PGR
11	mammary gland development	GO:0030879	9.35	PGR HOXD9 HOXA9
12	mesonephric tubule development	GO:0072164	9.32	WNT4 PAX8
13	cellular response to gonadotropin stimulus	GO:0071371	9.1	WT1 SLC5A5 PAX8

Molecular functions related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA-binding transcription activator activity, RNA polymerase II-specific	GO:0001228	9.73	WT1 TP53 PGR PAX8 HOXA9 HOXA7
2	DNA-binding transcription factor activity	GO:0003700	9.4	WT1 TP53 PGR PAX8 HOXD9 HOXA9

Sources

Sources for Ovarian Serous Cystadenofibroma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: OVR002 MIFTS: 29	Ovarian Serous Cystadenofibroma Categories: Cancer diseases, Endocrine diseases, Reproductive diseases	Data Licensing For inquiries, contact: [email protected]
Genes Related diseases Publications Symptoms & Phenotypes Expand all tables