MCID: OVR002
MIFTS: 29

Ovarian Serous Cystadenofibroma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Serous Cystadenofibroma

MalaCards integrated aliases for Ovarian Serous Cystadenofibroma:

Name: Ovarian Serous Cystadenofibroma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7320
NCIt 50 C40032
UMLS 70 C0877572

Summaries for Ovarian Serous Cystadenofibroma

Disease Ontology : 12 An ovarian serous adenofibroma that is characterized by the presence of cysts or cystic spaces.

MalaCards based summary : Ovarian Serous Cystadenofibroma is related to cystadenofibroma and papillary carcinoma, and has symptoms including abdominal pain An important gene associated with Ovarian Serous Cystadenofibroma is CALB2 (Calbindin 2), and among its related pathways/superpathways are DNA Damage Induced 14-3-3Sigma Signaling and Thyroxine (Thyroid Hormone) Production. Affiliated tissues include lung, breast and thyroid, and related phenotypes are endocrine/exocrine gland and limbs/digits/tail

Related Diseases for Ovarian Serous Cystadenofibroma

Diseases related to Ovarian Serous Cystadenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 244)
# Related Disease Score Top Affiliating Genes
1 cystadenofibroma 30.2 TP53 MUC1 KRT7 INHA CALB2
2 papillary carcinoma 29.8 TG MUC1 KRT7 CALB2
3 clear cell adenofibroma 10.6
4 spindle cell thymoma 10.4 MUC1 CALB2
5 lung sarcomatoid carcinoma 10.4 MUC1 CALB2
6 rete testis adenoma 10.4 NCAM1 CALB2
7 adult type testicular granulosa cell tumor 10.4 NCAM1 CALB2
8 pericardial mesothelioma 10.4 MUC1 CALB2
9 infected hydrocele 10.3 NCAM1 CALB2
10 esophageal neuroendocrine tumor 10.3 NCAM1 MUC1
11 fallopian tube adenocarcinoma 10.3 CALB2 BRCA1
12 chordoid meningioma 10.3 NCAM1 MUC1
13 transitional meningioma 10.3 NCAM1 MUC1
14 ovarian gonadoblastoma 10.3 WNT4 CALB2
15 ovarian small cell carcinoma 10.3 MUC1 INHA CALB2
16 microcystic adenoma 10.3 MUC1 INHA
17 rete testis neoplasm 10.2 KRT7 CALB2
18 rete testis adenocarcinoma 10.2 KRT7 CALB2
19 bartholin's gland disease 10.2 KRT7 CALB2
20 scrotum paget's disease 10.2 MUC1 KRT7
21 dermoid cyst of ovary 10.2 CALB2 AMH
22 gallbladder signet ring cell adenocarcinoma 10.2 MUC1 KRT7
23 epididymal neoplasm 10.2 KRT7 CALB2
24 urinary bladder villous adenoma 10.2 MUC1 KRT7
25 wolffian duct adenocarcinoma 10.2 KRT7 CALB2
26 pericardium cancer 10.2 KRT7 CALB2
27 mucinous intrahepatic cholangiocarcinoma 10.2 MUC1 KRT7
28 middle ear adenoma 10.2 MUC1 KRT7
29 uterus perivascular epithelioid cell tumor 10.2 KRT7 CALB2
30 bile duct cystadenocarcinoma 10.2 MUC1 KRT7
31 colonic lymphangioma 10.2 MUC1 KRT7
32 nephrogenic adenoma of the urethra 10.2 KRT7 CALB2
33 mucinous stomach adenocarcinoma 10.2 KRT7 CALB2
34 biliary papillomatosis 10.2 MUC1 KRT7
35 bile duct mucoepidermoid carcinoma 10.2 MUC1 KRT7
36 lipoadenoma 10.2 MUC1 KRT7
37 parachordoma 10.2 MUC1 KRT7
38 nephrogenic adenoma 10.2 MUC1 KRT7
39 thymus clear cell carcinoma 10.2 KRT7 CALB2
40 pancreatic serous cystadenocarcinoma 10.2 NCAM1 KRT7
41 liver leiomyosarcoma 10.2 KRT7 CALB2
42 lung leiomyosarcoma 10.2 KRT7 CALB2
43 gallbladder small cell carcinoma 10.2 NCAM1 KRT7
44 mucinous tubular and spindle renal cell carcinoma 10.2 MUC1 KRT7
45 ureter small cell carcinoma 10.2 NCAM1 KRT7
46 ovarian sex-cord stromal tumor 10.2 KRT7 CALB2
47 urinary bladder small cell neuroendocrine carcinoma 10.2 NCAM1 KRT7
48 sensory organ benign neoplasm 10.2 NCAM1 KRT7
49 epididymis adenocarcinoma 10.2 KRT7 CALB2
50 epididymis cancer 10.2 KRT7 CALB2

Graphical network of the top 20 diseases related to Ovarian Serous Cystadenofibroma:



Diseases related to Ovarian Serous Cystadenofibroma

Symptoms & Phenotypes for Ovarian Serous Cystadenofibroma

UMLS symptoms related to Ovarian Serous Cystadenofibroma:


abdominal pain

MGI Mouse Phenotypes related to Ovarian Serous Cystadenofibroma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.96 AMH BRCA1 HOXA7 HOXA9 HOXD9 INHA
2 limbs/digits/tail MP:0005371 9.63 BRCA1 HOXA9 HOXD9 TG TP53 WNT4
3 reproductive system MP:0005389 9.56 AMH BRCA1 HOXA9 HOXD9 INHA TG
4 skeleton MP:0005390 9.28 BRCA1 HOXA7 HOXA9 HOXD9 INHA SLC5A5

Drugs & Therapeutics for Ovarian Serous Cystadenofibroma

Search Clinical Trials , NIH Clinical Center for Ovarian Serous Cystadenofibroma

Genetic Tests for Ovarian Serous Cystadenofibroma

Anatomical Context for Ovarian Serous Cystadenofibroma

MalaCards organs/tissues related to Ovarian Serous Cystadenofibroma:

40
Lung, Breast, Thyroid, Ovary, Testis, Kidney, Liver

Publications for Ovarian Serous Cystadenofibroma

Articles related to Ovarian Serous Cystadenofibroma:

(show all 13)
# Title Authors PMID Year
1
Low-grade serous carcinoma with extensive osseous metaplasia arising from ovarian serous cystadenofibroma. 61
33553558 2021
2
Coexistence of genital tuberculosis and ovarian serous cystadenofibroma in a young female patient: a case report. 61
33045892 2020
3
Psammoma bodies in Papanicolaou tests and associated factors to predict an underlying malignancy: a clinicopathological analysis of 10 cases. 61
32376242 2020
4
Serous Tubal Intraepithelial Carcinoma (STIC)-like Lesions Arising in Ovarian Serous Cystadenofibroma: Report of 2 Cases. 61
26107558 2015
5
An unusual case of a borderline Brenner tumor associated with bilateral serous cystadenoma and endometrial carcinoma. 61
24791367 2014
6
False-positive I-131 uptake by an ovarian serous cystadenofibroma. 61
22228346 2012
7
Ovarian serous cystadenofibroma with signet ring-stromal cells: report of 2 cases. 61
20736763 2010
8
Extensive pelvic calcification in association with ovarian serous cystadenofibroma. 61
18840187 2008
9
Ovarian serous cystadenofibroma with stromal sex cord elements: report of a unique case. 61
16990708 2006
10
Eosinophilic hyperplasia of fallopian tube mucosa. 61
9798416 1998
11
Longstanding ovarian serous cystadenofibroma sonographically mimicking a urachal cyst. 61
8822669 1996
12
Ovarian serous cystadenofibroma of borderline malignancy: report of two cases. 61
7372194 1980
13
The ovarian serous cystadenofibroma; a report of 25 cases. 61
13649808 1959

Variations for Ovarian Serous Cystadenofibroma

Expression for Ovarian Serous Cystadenofibroma

Search GEO for disease gene expression data for Ovarian Serous Cystadenofibroma.

Pathways for Ovarian Serous Cystadenofibroma

Pathways related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.23 TP53 BRCA1
2 9.4 TG SLC5A5

GO Terms for Ovarian Serous Cystadenofibroma

Biological processes related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 male gonad development GO:0008584 9.54 WNT4 INHA HOXA9
2 anterior/posterior pattern specification GO:0009952 9.5 HOXD9 HOXA9 HOXA7
3 negative regulation of reactive oxygen species metabolic process GO:2000378 9.43 TP53 BRCA1
4 thyroid hormone generation GO:0006590 9.4 TG SLC5A5
5 embryonic skeletal system morphogenesis GO:0048704 9.33 HOXD9 HOXA9 HOXA7
6 positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003 9.26 TP53 MUC1
7 iodide transport GO:0015705 8.96 TG SLC5A5
8 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.8 TP53 MUC1 BRCA1

Molecular functions related to Ovarian Serous Cystadenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 TG INHA AMH

Sources for Ovarian Serous Cystadenofibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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