MCID: OVR027
MIFTS: 23

Ovarian Squamous Cell Carcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovarian Squamous Cell Carcinoma

MalaCards integrated aliases for Ovarian Squamous Cell Carcinoma:

Name: Ovarian Squamous Cell Carcinoma 12 15 17 72
Ovarian Squamous Cell Tumor 72

Classifications:



External Ids:

Disease Ontology 12 DOID:5531
NCIt 50 C40093
UMLS 72 C1518739 C2019443

Summaries for Ovarian Squamous Cell Carcinoma

Disease Ontology : 12 An ovarian carcinoma that derives from squamous epithelial cells.

MalaCards based summary : Ovarian Squamous Cell Carcinoma, also known as ovarian squamous cell tumor, is related to squamous cell carcinoma and cystic teratoma. An important gene associated with Ovarian Squamous Cell Carcinoma is SLC2A1 (Solute Carrier Family 2 Member 1). The drugs Temozolomide and Hydroxyurea have been mentioned in the context of this disorder. Affiliated tissues include ovary and cervix.

Related Diseases for Ovarian Squamous Cell Carcinoma

Diseases related to Ovarian Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma 10.5
2 cystic teratoma 10.4
3 teratoma 10.4
4 dermoid cyst 10.3
5 endometriosis 10.3
6 mature teratoma 10.3
7 suppressor of tumorigenicity 3 10.1
8 ovarian brenner tumor 10.1
9 colorectal cancer 9.9
10 cervical cancer 9.9
11 endometriosis of ovary 9.9
12 squamous cell papilloma 9.9
13 papilloma 9.9
14 cervical squamous cell carcinoma 9.9
15 large cell carcinoma 9.9
16 in situ carcinoma 9.9
17 cervix uteri carcinoma in situ 9.9
18 cervical intraepithelial neoplasia 9.9

Graphical network of the top 20 diseases related to Ovarian Squamous Cell Carcinoma:



Diseases related to Ovarian Squamous Cell Carcinoma

Symptoms & Phenotypes for Ovarian Squamous Cell Carcinoma

Drugs & Therapeutics for Ovarian Squamous Cell Carcinoma

Drugs for Ovarian Squamous Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Temozolomide Approved, Investigational Phase 1 85622-93-1 5394
2
Hydroxyurea Approved Phase 1 127-07-1 3657
3
carbamide peroxide Approved Phase 1 124-43-6
4 Alkylating Agents Phase 1
5 Nucleic Acid Synthesis Inhibitors Phase 1
6 Antineoplastic Agents, Alkylating Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 International Multicenter Phase I Trial of Hydroxyurea in Combination With Dose-Intense Temozolomide in Recurrent Glioblastoma Recruiting NCT03463733 Phase 1 Hydroxyurea;Temozolomide

Search NIH Clinical Center for Ovarian Squamous Cell Carcinoma

Genetic Tests for Ovarian Squamous Cell Carcinoma

Anatomical Context for Ovarian Squamous Cell Carcinoma

MalaCards organs/tissues related to Ovarian Squamous Cell Carcinoma:

41
Ovary, Cervix

Publications for Ovarian Squamous Cell Carcinoma

Articles related to Ovarian Squamous Cell Carcinoma:

(show all 28)
# Title Authors PMID Year
1
Overexpression of CASC11 in ovarian squamous cell carcinoma mediates the development of cancer cell resistance to chemotherapy. 38
31181314 2019
2
MiR-1204 promotes ovarian squamous cell carcinoma growth by increasing glucose uptake. 38
30304996 2018
3
A case of pure-type ovarian squamous cell carcinoma producing granulocyte-colony stimulating factor. 38
29159261 2017
4
Long-term recurrence-free survival of a patient with advanced pure primary ovarian squamous cell carcinoma treated with dose-dense paclitaxel combined with carboplatin. 38
29184868 2017
5
Pure Primary Ovarian Squamous Cell Carcinoma Perforating the Rectum. 38
28316851 2017
6
Case of pure ovarian squamous cell carcinoma resistant to combination chemotherapy with paclitaxel and carboplatin but responsive to monotherapy with weekly irinotecan. 38
25511544 2015
7
Pure primary ovarian squamous cell carcinoma: A case report and review of the literature. 38
25435984 2015
8
Clinical experience in ovarian squamous cell carcinoma arising from mature cystic teratoma: A rare entity. 38
25105100 2014
9
De novo Ovarian Squamous Cell Carcinoma. A Case Report and Review of Literature. 38
24426735 2013
10
Bilateral ovarian squamous cell carcinoma with an antecedent dermoid cyst in the left ovary. 38
21518128 2011
11
Ultrasonography for leukocytosis or elevated C-reactive protein. 38
21937369 2011
12
Ovarian squamous cell carcinoma which metastasized 8 years after cervical conization for early microinvasive cervical cancer: a case report. 38
21467082 2011
13
Ovarian squamous cell carcinoma arising from mature cystic teratoma. 38
21684828 2011
14
Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: a case report with literature review. 38
20852876 2011
15
A case of squamous cell carcinoma arising from endometriosis of the ovary. 38
22053674 2011
16
Metastatic ovarian squamous cell carcinoma. 38
18465040 2008
17
De novo primary squamous cell carcinoma of the ovary: a case of a rare malignancy with an aggressive clinical course. 38
18655408 2008
18
HPV induced ovarian squamous cell carcinoma: case report and review of the literature. 38
17333225 2007
19
[Primary squamous cell carcinoma of the ovary]. 38
16324442 2005
20
A case of pure-type ovarian squamous cell carcinoma for which combination chemotherapy consisting of paclitaxel and carboplatin was not effective. 38
15790463 2005
21
A case of rapidly growing ovarian squamous cell carcinoma successfully controlled by weekly paclitaxel-carboplatin administration. 38
11104632 2000
22
Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary. 38
9610706 1998
23
Bilateral primary ovarian squamous cell carcinoma associated with human papilloma virus infection and vulvar and cervical intraepithelial neoplasia. A case report with review of the literature. 38
8651358 1996
24
Pure primary ovarian squamous cell carcinoma. 38
3276582 1988
25
[A case report of ovarian squamous cell carcinoma developing into a dermoid cyst with malignant transformation--immunohistochemical study]. 38
2447309 1987
26
Squamous cell carcinoma of the ovary. 38
3632305 1987
27
Ovarian squamous cell carcinoma derived from a dermoid cyst presenting as vaginal metastasis and the implication of its steroid receptor levels--two case reports. 38
3943751 1986
28
Squamous cell carcinoma arising from an epidermoid cyst in the ovary of a rat treated with 7,12-dimethylbenz[a]anthracene. 38
6811356 1982

Variations for Ovarian Squamous Cell Carcinoma

Expression for Ovarian Squamous Cell Carcinoma

Search GEO for disease gene expression data for Ovarian Squamous Cell Carcinoma.

Pathways for Ovarian Squamous Cell Carcinoma

GO Terms for Ovarian Squamous Cell Carcinoma

Sources for Ovarian Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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