MCID: OVR026
MIFTS: 21

Ovary Transitional Cell Carcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovary Transitional Cell Carcinoma

MalaCards integrated aliases for Ovary Transitional Cell Carcinoma:

Name: Ovary Transitional Cell Carcinoma 12 15
Malignant Ovarian Transitional Cell Neoplasm 12
Malignant Ovarian Transitional Cell Tumor 72
Transitional Cell Carcinoma of Ovary 12
Ovarian Transitional Cell Carcinoma 17
Ovarian Transitional Cell Neoplasm 12
Ovarian Transitional Cell Cancer 12
Ovarian Transitional Cell Tumor 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4000
UMLS 72 C1335184 C1335185 C1518237

Summaries for Ovary Transitional Cell Carcinoma

Disease Ontology : 12 An ovarian epithelial cancer that derives from epithelial transitional cells.

MalaCards based summary : Ovary Transitional Cell Carcinoma, also known as malignant ovarian transitional cell neoplasm, is related to transitional cell carcinoma and hydronephrosis. An important gene associated with Ovary Transitional Cell Carcinoma is HNF1B (HNF1 Homeobox B). Affiliated tissues include ovary.

Related Diseases for Ovary Transitional Cell Carcinoma

Diseases related to Ovary Transitional Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 transitional cell carcinoma 10.1
2 hydronephrosis 9.9
3 signet ring cell adenocarcinoma 9.9
4 breast cancer 9.9
5 dermatomyositis 9.9
6 adenocarcinoma 9.9
7 serous cystadenocarcinoma 9.9
8 bladder urothelial carcinoma 9.9
9 ovarian cancer 9.5 HNF1B ERBB3

Graphical network of the top 20 diseases related to Ovary Transitional Cell Carcinoma:



Diseases related to Ovary Transitional Cell Carcinoma

Symptoms & Phenotypes for Ovary Transitional Cell Carcinoma

Drugs & Therapeutics for Ovary Transitional Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Ovary Transitional Cell Carcinoma

Genetic Tests for Ovary Transitional Cell Carcinoma

Anatomical Context for Ovary Transitional Cell Carcinoma

MalaCards organs/tissues related to Ovary Transitional Cell Carcinoma:

41
Ovary

Publications for Ovary Transitional Cell Carcinoma

Articles related to Ovary Transitional Cell Carcinoma:

# Title Authors PMID Year
1
Primary ovary transitional cell carcinoma after renal transplantation. 38
21550011 2011
2
[Transitional cell carcinoma of the ovary: one kind of uncommon type of ovarian epithelial carcinoma]. 38
12622917 2002
3
[Overexpression of C-erbB3 in transitional cell carcinoma of the ovary]. 38
8745489 1995

Variations for Ovary Transitional Cell Carcinoma

Cosmic variations for Ovary Transitional Cell Carcinoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM11450 TP53 ovary,NS,carcinoma,transitional cell carcinoma c.644G>T p.S215I 17:7674887-7674887 9
2 COSM10648 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.524G>A p.R175H 17:7675088-7675088 9
3 COSM10733 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.574C>T p.Q192* 17:7674957-7674957 9
4 COSM10660 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 9
5 COSM11552 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.775G>T p.D259Y 17:7674188-7674188 9
6 COSM44877 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.584T>A p.I195N 17:7674947-7674947 9
7 COSM45672 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.376-2A>G p.? 17:7675238-7675238 9
8 COSM13584 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.919+1G>T p.? 17:7673700-7673700 9
9 COSM96412 CREBBP ovary,NS,carcinoma,transitional cell carcinoma c.1399G>A p.A467T 16:3782858-3782858 9

Expression for Ovary Transitional Cell Carcinoma

Search GEO for disease gene expression data for Ovary Transitional Cell Carcinoma.

Pathways for Ovary Transitional Cell Carcinoma

GO Terms for Ovary Transitional Cell Carcinoma

Biological processes related to Ovary Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 8.65 HNF1B
2 positive regulation of gene expression GO:0010628 8.62 HNF1B ERBB3

Molecular functions related to Ovary Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.96 HNF1B ERBB3
2 protein heterodimerization activity GO:0046982 8.62 HNF1B ERBB3

Sources for Ovary Transitional Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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