MCID: OVR026
MIFTS: 24

Ovary Transitional Cell Carcinoma

Categories: Cancer diseases, Endocrine diseases, Reproductive diseases

Aliases & Classifications for Ovary Transitional Cell Carcinoma

MalaCards integrated aliases for Ovary Transitional Cell Carcinoma:

Name: Ovary Transitional Cell Carcinoma 12 15
Malignant Ovarian Transitional Cell Neoplasm 12
Malignant Ovarian Transitional Cell Tumor 71
Transitional Cell Carcinoma of Ovary 12
Ovarian Transitional Cell Carcinoma 17
Ovarian Transitional Cell Neoplasm 12
Ovarian Transitional Cell Cancer 12
Ovarian Transitional Cell Tumor 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4000
UMLS 71 C1335184 C1335185 C1518237

Summaries for Ovary Transitional Cell Carcinoma

Disease Ontology : 12 An ovarian epithelial cancer that derives from epithelial transitional cells.

MalaCards based summary : Ovary Transitional Cell Carcinoma, also known as malignant ovarian transitional cell neoplasm, is related to transitional cell carcinoma and ovarian cancer. An important gene associated with Ovary Transitional Cell Carcinoma is HNF1B (HNF1 Homeobox B). Affiliated tissues include ovary and breast.

Related Diseases for Ovary Transitional Cell Carcinoma

Diseases related to Ovary Transitional Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 transitional cell carcinoma 10.2
2 ovarian cancer 9.9
3 hydronephrosis 9.9
4 breast cancer 9.9
5 dermatomyositis 9.9
6 adenocarcinoma 9.9
7 serous cystadenocarcinoma 9.9
8 bladder urothelial carcinoma 9.9
9 renal cell carcinoma, nonpapillary 9.2 HNF1B ERBB3

Graphical network of the top 20 diseases related to Ovary Transitional Cell Carcinoma:



Diseases related to Ovary Transitional Cell Carcinoma

Symptoms & Phenotypes for Ovary Transitional Cell Carcinoma

Drugs & Therapeutics for Ovary Transitional Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Ovary Transitional Cell Carcinoma

Genetic Tests for Ovary Transitional Cell Carcinoma

Anatomical Context for Ovary Transitional Cell Carcinoma

MalaCards organs/tissues related to Ovary Transitional Cell Carcinoma:

40
Ovary, Breast

Publications for Ovary Transitional Cell Carcinoma

Articles related to Ovary Transitional Cell Carcinoma:

# Title Authors PMID Year
1
Primary ovary transitional cell carcinoma after renal transplantation. 61
21550011 2011
2
[Transitional cell carcinoma of the ovary: one kind of uncommon type of ovarian epithelial carcinoma]. 61
12622917 2002
3
[Overexpression of C-erbB3 in transitional cell carcinoma of the ovary]. 61
8745489 1995

Variations for Ovary Transitional Cell Carcinoma

Cosmic variations for Ovary Transitional Cell Carcinoma:

9 (show top 50) (show all 154)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM87905712 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.775G>T p.D259Y 17:7674188-7674188 9
2 COSM87929008 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.584T>A p.I195N 17:7674947-7674947 9
3 COSM87897745 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.524G>A p.R175H 17:7675088-7675088 9
4 COSM87909792 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.919+1G>T p.? 17:7673700-7673700 9
5 COSM87897711 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 9
6 COSM87912901 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.376-2A>G p.? 17:7675238-7675238 9
7 COSM87897627 TP53 ovary,NS,carcinoma,undifferentiated carcinoma c.574C>T p.Q192* 17:7674957-7674957 9
8 COSM87907717 TP53 ovary,NS,carcinoma,transitional cell carcinoma c.644G>T p.S215I 17:7674887-7674887 9
9 COSM84244848 CREBBP ovary,NS,carcinoma,transitional cell carcinoma c.1399G>A p.A467T 16:3782858-3782858 9
10 COSM93210112 ovary,NS,carcinoma,undifferentiated carcinoma c.584T>A p.I195N 17:7674947-7674947 9
11 COSM112265718 ovary,NS,carcinoma,undifferentiated carcinoma c.376-2A>G p.? 17:7675238-7675238 9
12 COSM121883757 ovary,NS,carcinoma,undifferentiated carcinoma c.379G>T p.D127Y 17:7674188-7674188 9
13 COSM144315359 ovary,NS,carcinoma,undifferentiated carcinoma c.658G>T p.D220Y 17:7674188-7674188 9
14 COSM143377204 ovary,NS,carcinoma,undifferentiated carcinoma c.658G>T p.D220Y 17:7674188-7674188 9
15 COSM121890133 ovary,NS,carcinoma,undifferentiated carcinoma c.-23A>G p.? 17:7675238-7675238 9
16 COSM112259562 ovary,NS,carcinoma,undifferentiated carcinoma c.775G>T p.D259Y 17:7674188-7674188 9
17 COSM145017220 ovary,NS,carcinoma,undifferentiated carcinoma c.457C>T p.Q153* 17:7674957-7674957 9
18 COSM144013113 ovary,NS,carcinoma,undifferentiated carcinoma c.491G>A p.R164H 17:7675088-7675088 9
19 COSM143950904 ovary,NS,carcinoma,transitional cell carcinoma c.167G>T p.S56I 17:7674887-7674887 9
20 COSM106052835 ovary,NS,carcinoma,undifferentiated carcinoma c.574C>T p.Q192* 17:7674957-7674957 9
21 COSM105628995 ovary,NS,carcinoma,transitional cell carcinoma c.644G>T p.S215I 17:7674887-7674887 9
22 COSM106065581 ovary,NS,carcinoma,undifferentiated carcinoma c.376-2A>G p.? 17:7675238-7675238 9
23 COSM142568038 ovary,NS,carcinoma,transitional cell carcinoma c.527G>T p.S176I 17:7674887-7674887 9
24 COSM143384685 ovary,NS,carcinoma,undifferentiated carcinoma c.259-2A>G p.? 17:7675238-7675238 9
25 COSM145027383 ovary,NS,carcinoma,undifferentiated carcinoma c.802+1G>T p.? 17:7673700-7673700 9
26 COSM143370507 ovary,NS,carcinoma,undifferentiated carcinoma c.457C>T p.Q153* 17:7674957-7674957 9
27 COSM122760210 ovary,NS,carcinoma,undifferentiated carcinoma c.188T>A p.I63N 17:7674947-7674947 9
28 COSM93193704 ovary,NS,carcinoma,undifferentiated carcinoma c.919+1G>T p.? 17:7673700-7673700 9
29 COSM111758217 ovary,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 9
30 COSM143381454 ovary,NS,carcinoma,undifferentiated carcinoma c.802+1G>T p.? 17:7673700-7673700 9
31 COSM143167165 ovary,NS,carcinoma,undifferentiated carcinoma c.-104A>G p.? 17:7675238-7675238 9
32 COSM145017326 ovary,NS,carcinoma,undifferentiated carcinoma c.407G>A p.R136H 17:7675088-7675088 9
33 COSM121875437 ovary,NS,carcinoma,undifferentiated carcinoma c.178C>T p.Q60* 17:7674957-7674957 9
34 COSM122271291 ovary,NS,carcinoma,undifferentiated carcinoma c.128G>A p.R43H 17:7675088-7675088 9
35 COSM144012970 ovary,NS,carcinoma,undifferentiated carcinoma c.541C>T p.Q181* 17:7674957-7674957 9
36 COSM142846634 ovary,NS,carcinoma,undifferentiated carcinoma c.376-2A>G p.? 17:7675238-7675238 9
37 COSM144650676 ovary,NS,carcinoma,undifferentiated carcinoma c.457C>T p.Q153* 17:7674957-7674957 9
38 COSM112253051 ovary,NS,carcinoma,undifferentiated carcinoma c.574C>T p.Q192* 17:7674957-7674957 9
39 COSM112253106 ovary,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 9
40 COSM143943506 ovary,NS,carcinoma,undifferentiated carcinoma c.97C>T p.Q33* 17:7674957-7674957 9
41 COSM144021629 ovary,NS,carcinoma,transitional cell carcinoma c.611G>T p.S204I 17:7674887-7674887 9
42 COSM145029876 ovary,NS,carcinoma,undifferentiated carcinoma c.259-2A>G p.? 17:7675238-7675238 9
43 COSM111758247 ovary,NS,carcinoma,undifferentiated carcinoma c.524G>A p.R175H 17:7675088-7675088 9
44 COSM143949177 ovary,NS,carcinoma,undifferentiated carcinoma c.298G>T p.D100Y 17:7674188-7674188 9
45 COSM121887348 ovary,NS,carcinoma,undifferentiated carcinoma c.523+1G>T p.? 17:7673700-7673700 9
46 COSM122740139 ovary,NS,carcinoma,undifferentiated carcinoma c.379G>T p.D127Y 17:7674188-7674188 9
47 COSM144086975 ovary,NS,carcinoma,undifferentiated carcinoma c.47G>A p.R16H 17:7675088-7675088 9
48 COSM121875575 ovary,NS,carcinoma,undifferentiated carcinoma c.128G>A p.R43H 17:7675088-7675088 9
49 COSM93183281 ovary,NS,carcinoma,undifferentiated carcinoma c.818G>A p.R273H 17:7673802-7673802 9
50 COSM122271198 ovary,NS,carcinoma,undifferentiated carcinoma c.178C>T p.Q60* 17:7674957-7674957 9

Expression for Ovary Transitional Cell Carcinoma

Search GEO for disease gene expression data for Ovary Transitional Cell Carcinoma.

Pathways for Ovary Transitional Cell Carcinoma

GO Terms for Ovary Transitional Cell Carcinoma

Biological processes related to Ovary Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 8.62 HNF1B ERBB3

Molecular functions related to Ovary Transitional Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.96 HNF1B ERBB3
2 protein heterodimerization activity GO:0046982 8.62 HNF1B ERBB3

Sources for Ovary Transitional Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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