MCID: OVR096
MIFTS: 20

Overlap Myositis

Categories: Neuronal diseases, Bone diseases, Rare diseases

Aliases & Classifications for Overlap Myositis

MalaCards integrated aliases for Overlap Myositis:

Name: Overlap Myositis 59
Adult-Onset Overlap Myositis 59
Non-Specific Myositis 59
Myositis 73

Characteristics:

Orphanet epidemiological data:

59
overlap myositis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:



External Ids:

Orphanet 59 ORPHA206572

Summaries for Overlap Myositis

MalaCards based summary : Overlap Myositis, also known as adult-onset overlap myositis, is related to juvenile overlap myositis and myositis, and has symptoms including back pain, muscle cramp and muscle rigidity. The drugs Abatacept and Immunosuppressive Agents have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Overlap Myositis

Diseases in the Overlap Myositis family:

Juvenile Overlap Myositis

Diseases related to Overlap Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 juvenile overlap myositis 12.3
2 myositis 10.0
3 dermatomyositis 9.8
4 polymyositis 9.8
5 scleroderma, familial progressive 9.6
6 tetrasomy 9p 9.6

Graphical network of the top 20 diseases related to Overlap Myositis:



Diseases related to Overlap Myositis

Symptoms & Phenotypes for Overlap Myositis

UMLS symptoms related to Overlap Myositis:


back pain, muscle cramp, muscle rigidity, muscle spasticity, myoclonus, sciatica, torticollis, muscle weakness, myalgia

Drugs & Therapeutics for Overlap Myositis

Drugs for Overlap Myositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abatacept Approved Phase 3 332348-12-6 10237
2 Immunosuppressive Agents Phase 3
3 Antirheumatic Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy Recruiting NCT02971683 Phase 3 Abatacept subcutaneous;Placebo

Search NIH Clinical Center for Overlap Myositis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Overlap Myositis

Anatomical Context for Overlap Myositis

MalaCards organs/tissues related to Overlap Myositis:

41
Bone

Publications for Overlap Myositis

Articles related to Overlap Myositis:

# Title Authors Year
1
Mosaic Tetrasomy 9p: A Mendelian Condition Associated With Pediatric-Onset Overlap Myositis. ( 26216333 )
2015
2
Redefining dermatomyositis: a description of new diagnostic criteria that differentiate pure dermatomyositis from overlap myositis with dermatomyositis features. ( 25500701 )
2014
3
Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku. ( 22453528 )
2013
4
Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis. ( 21376512 )
2011
5
Cardiac involvement in juvenile overlap-myositis detected by cardiac magnetic resonance imaging. ( 20971516 )
2011
6
Myositis-specific and myositis-associated antibodies in overlap myositis in comparison to primary dermatopolymyositis: Relevance for clinical classification: retrospective study of 169 patients. ( 20188618 )
2010

Variations for Overlap Myositis

Expression for Overlap Myositis

Search GEO for disease gene expression data for Overlap Myositis.

Pathways for Overlap Myositis

GO Terms for Overlap Myositis

Sources for Overlap Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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