MCID: OVR096
MIFTS: 21

Overlap Myositis

Categories: Bone diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Overlap Myositis

MalaCards integrated aliases for Overlap Myositis:

Name: Overlap Myositis 60
Adult-Onset Overlap Myositis 60
Non-Specific Myositis 60
Myositis 74

Characteristics:

Orphanet epidemiological data:

60
overlap myositis
Inheritance: Not applicable; Age of onset: Adult;

Classifications:



External Ids:

Orphanet 60 ORPHA206572
UMLS 74 C0027121

Summaries for Overlap Myositis

MalaCards based summary : Overlap Myositis, also known as adult-onset overlap myositis, is related to juvenile overlap myositis and myositis, and has symptoms including muscle weakness, myoclonus and back pain. The drugs Abatacept and Immunosuppressive Agents have been mentioned in the context of this disorder. Affiliated tissues include bone.

Related Diseases for Overlap Myositis

Diseases in the Overlap Myositis family:

Juvenile Overlap Myositis

Diseases related to Overlap Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 juvenile overlap myositis 12.5
2 myositis 10.2
3 dermatomyositis 9.9
4 polymyositis 9.9
5 scleroderma, familial progressive 9.8
6 tetrasomy 9p 9.8

Graphical network of the top 20 diseases related to Overlap Myositis:



Diseases related to Overlap Myositis

Symptoms & Phenotypes for Overlap Myositis

UMLS symptoms related to Overlap Myositis:


muscle weakness, myoclonus, back pain, myalgia, torticollis, sciatica, muscle cramp, muscle rigidity, muscle spasticity

Drugs & Therapeutics for Overlap Myositis

Drugs for Overlap Myositis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Abatacept Approved Phase 3 332348-12-6 10237
2 Immunosuppressive Agents Phase 3
3 Antirheumatic Agents Phase 3
4 Immunologic Factors Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy Recruiting NCT02971683 Phase 3 Abatacept subcutaneous;Placebo

Search NIH Clinical Center for Overlap Myositis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Genetic Tests for Overlap Myositis

Anatomical Context for Overlap Myositis

MalaCards organs/tissues related to Overlap Myositis:

42
Bone

Publications for Overlap Myositis

Articles related to Overlap Myositis:

# Title Authors Year
1
Overlap myositis, a distinct entity beyond primary inflammatory myositis: A retrospective analysis of a large cohort from the REMICAM registry. ( 30968571 )
2019
2
The clinico-serological spectrum of overlap myositis. ( 30074509 )
2018
3
Mosaic Tetrasomy 9p: A Mendelian Condition Associated With Pediatric-Onset Overlap Myositis. ( 26216333 )
2015
4
Redefining dermatomyositis: a description of new diagnostic criteria that differentiate pure dermatomyositis from overlap myositis with dermatomyositis features. ( 25500701 )
2014
5
Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku. ( 22453528 )
2013
6
Pathogenic aspects of dermatomyositis, polymyositis and overlap myositis. ( 21376512 )
2011
7
Cardiac involvement in juvenile overlap-myositis detected by cardiac magnetic resonance imaging. ( 20971516 )
2011
8
Myositis-specific and myositis-associated antibodies in overlap myositis in comparison to primary dermatopolymyositis: Relevance for clinical classification: retrospective study of 169 patients. ( 20188618 )
2010

Variations for Overlap Myositis

Expression for Overlap Myositis

Search GEO for disease gene expression data for Overlap Myositis.

Pathways for Overlap Myositis

GO Terms for Overlap Myositis

Sources for Overlap Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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