Categories: Metabolic diseases

Aliases & Classifications for Overnutrition

MalaCards integrated aliases for Overnutrition:

Name: Overnutrition 12 43 15 71


External Ids:

Disease Ontology 12 DOID:654
MeSH 43 D044343
SNOMED-CT 67 302872003
UMLS 71 C1257763

Summaries for Overnutrition

Disease Ontology : 12 A nutrition disease that is characterized by an excess of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content.

MalaCards based summary : Overnutrition is related to nutritional deficiency disease and body mass index quantitative trait locus 11. An important gene associated with Overnutrition is INS (Insulin), and among its related pathways/superpathways are AMP-activated Protein Kinase (AMPK) Signaling and Circadian rythm related genes. The drugs Clotrimazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and brain, and related phenotypes are adipose tissue and liver/biliary system

Wikipedia : 74 Overnutrition is a form of malnutrition in which the intake of nutrients is oversupplied. The amount of... more...

Related Diseases for Overnutrition

Diseases related to Overnutrition via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 265)
# Related Disease Score Top Affiliating Genes
1 nutritional deficiency disease 33.6 SERPINA3 LEP H2AC18 CCR6 ADIPOQ
2 body mass index quantitative trait locus 11 33.5 SOCS3 SERPINA3 PPARG MIR378A MIR21 MIR199A1
3 hyperinsulinism 31.9 PPARG LEP INS ADIPOQ
4 fatty liver disease 31.9 PPARG MIR21 MIR155 MIR122 LEP INS
5 fatty liver disease, nonalcoholic 1 31.8 LEP INS ADIPOQ
6 glucose intolerance 31.8 PPARG LEP INS ADIPOQ
7 hyperglycemia 31.8 PPARG MIR126 LEP INS ADIPOQ
8 gestational diabetes 31.7 PPARG LEP INS FTO ADIPOQ
9 lipid metabolism disorder 31.7 PPARG MIR21 MIR126 MIR122 LEP INS
10 non-alcoholic fatty liver disease 31.5 SOCS3 PPARG MIR378A MIR21 MIR199A1 MIR155
11 liver disease 31.5 SERPINA3 MIR122 LEP INS ADIPOQ
12 atherosclerosis susceptibility 31.5 PPARG LEP INS ADIPOQ
13 non-alcoholic steatohepatitis 31.4 PPARG MIR21 MIR122 INS ADIPOQ
14 mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome 31.2 LEP INS ADIPOQ
15 acanthosis nigricans 31.2 PPARG LEP INS ADIPOQ
16 kidney cancer 31.2 MIR378A MIR21 MIR199A1 MIR126 MIR122 INS
17 lymphoma, non-hodgkin, familial 31.2 SERPINA3 MIR21 MIR199A1 MIR155 MIR126 H2AC18
18 myeloma, multiple 31.1 SERPINA3 MIR21 MIR199A1 MIR126 H2AC18 CCR6
19 hypervitaminosis a 11.5
20 hypervitaminosis d 11.2
21 lipodystrophy, congenital generalized, type 1 10.9 PPARG LEP INS ADIPOQ
22 abdominal obesity-metabolic syndrome quantitative trait locus 2 10.9 PPARG LEP INS ADIPOQ
23 complete generalized lipodystrophy 10.9 PPARG LEP INS ADIPOQ
24 adult syndrome 10.9 PPARG LEP INS H2AC18 ADIPOQ
25 leptin deficiency or dysfunction 10.9 SOCS3 PPARG LEP INS FTO AGRP
26 maturity-onset diabetes of the young, type 1 10.9 PPARG LEP INS ADIPOQ
27 prediabetes syndrome 10.9 SERPINA3 PPARG MIR126 LEP INS ADIPOQ
28 maturity-onset diabetes of the young 10.9 PPARG LEP INS H2AC18 FTO
29 bone remodeling disease 10.8 SERPINA3 MIR199A1 MIR122 LEP INS H2AC18
30 gastrointestinal system benign neoplasm 10.8 SERPINA3 MIR21 MIR199A1 INS H2AC18 CCR6
31 thyroid gland disease 10.8 SERPINA3 PPARG MIR199A1 LEP INS H2AC18
32 heart conduction disease 10.8 SERPINA3 MIR21 MIR199A1 MIR126 INS H2AC18
33 abdominal obesity-metabolic syndrome 1 10.8 PPARG MIR122 LEP INS ADIPOQ
34 extrinsic cardiomyopathy 10.8 SERPINA3 MIR21 MIR199A1 H2AC18 CCR6
35 retinal vascular disease 10.8 MIR21 MIR199A1 MIR126 INS H2AC18
36 placenta disease 10.8 SERPINA3 MIR199A1 INS H2AC18 ADIPOQ
37 lipodystrophy, familial partial, type 2 10.8 PPARG LEP INS ADIPOQ
38 diabetes mellitus 10.8 SOCS3 PPARG MIR155 MIR126 LEP INS
39 specific developmental disorder 10.8 SERPINA3 LEP INS H2AC18 CCR6
40 peripheral nervous system disease 10.8 SERPINA3 MIR21 MIR126 LEP INS H2AC18
41 substance abuse 10.8 SERPINA3 MIR199A1 INS H2AC18 CCR6
42 bacterial infectious disease 10.8 SERPINA3 MIR155 H2AC18 CCR6
43 intestinal benign neoplasm 10.8 SERPINA3 MIR21 MIR199A1 H2AC18 CCR6
44 acute cystitis 10.8 SERPINA3 INS H2AC18 CCR6
45 cell type benign neoplasm 10.8 SERPINA3 MIR21 MIR199A1 MIR126 INS H2AC18
46 familial partial lipodystrophy 10.8 PPARG LEP INS ADIPOQ
47 skin tag 10.8 SERPINA3 LEP INS
48 familial hyperlipidemia 10.8 PPARG LEP INS H2AC18 ADIPOQ
49 bile duct adenocarcinoma 10.8 SERPINA3 MIR21 MIR199A1 H2AC18 CCR6
50 cerebrovascular disease 10.8 SERPINA3 MIR21 MIR199A1 LEP INS ADIPOQ

Graphical network of the top 20 diseases related to Overnutrition:

Diseases related to Overnutrition

Symptoms & Phenotypes for Overnutrition

MGI Mouse Phenotypes related to Overnutrition:

# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.5 ADIPOQ AGRP FTO INS LEP PPARG
2 liver/biliary system MP:0005370 9.17 ADIPOQ AGRP FTO INS LEP PPARG

Drugs & Therapeutics for Overnutrition

Drugs for Overnutrition (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Clotrimazole Approved, Vet_approved Phase 4 23593-75-1 2812
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
Micafungin Approved, Investigational Phase 4 235114-32-6 477468 3081921
4 Antifungal Agents Phase 4
5 Anti-Infective Agents Phase 4
Naltrexone Approved, Investigational, Vet_approved Phase 3 16590-41-3 5360515
7 Nutmeg Approved Phase 3
Bupropion Approved Phase 3 34911-55-2, 34841-39-9 444
9 Anti-Obesity Agents Phase 3
10 Narcotics Phase 3
11 Mace Phase 3
12 Narcotic Antagonists Phase 3
13 Bupropion hydrochloride, naltrexone hydrochoride drug combination Phase 3
14 Pancreatic Polypeptide Investigational Phase 1, Phase 2 59763-91-6
15 Liver Extracts Phase 2
16 Anti-Allergic Agents Phase 2
17 Hormones Phase 1, Phase 2
18 Hormone Antagonists Phase 1, Phase 2
19 Gastrointestinal Agents Phase 1, Phase 2
Histamine Approved, Investigational Phase 1 51-45-6 774
Betahistine Approved, Investigational Phase 1 5638-76-6 2366
Morphine Approved, Investigational Phase 1 57-27-2 5288826
23 Vasodilator Agents Phase 1
Histamine Phosphate Phase 1 51-74-1 65513
25 Neurotransmitter Agents Phase 1
Glucagon Approved 16941-32-5
Orlistat Approved, Investigational 96829-58-2 3034010
Iron Approved, Experimental 15438-31-0, 7439-89-6 27284 23925
Zinc Approved, Investigational 7440-66-6 32051
Sulfamethazine Approved, Investigational, Vet_approved 57-68-1 5327
31 Coconut Approved Early Phase 1
32 Strawberry Approved Early Phase 1
Ethanol Approved Early Phase 1 64-17-5 702
Silicon Approved, Investigational Early Phase 1 7440-21-3 4082203
tannic acid Approved 1401-55-4
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
gastric inhibitory polypeptide Investigational 100040-31-1
Rosemary Experimental Early Phase 1
39 Whey Protein
40 Lipid Regulating Agents
41 Secretagogues
42 Olive
43 Incretins
44 Anti-Retroviral Agents
45 Hypoglycemic Agents
46 Trace Elements
47 Micronutrients
48 Vitamins
49 Omega 3 Fatty Acid
50 Soy Bean Early Phase 1

Interventional clinical trials:

(show all 43)
# Name Status NCT ID Phase Drugs
1 Pharmacokinetic Analysis of Micafungin in Overweight, Obese, and Extremely Obese Volunteers Completed NCT01090141 Phase 4 Micafungin;Micafungin
2 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Assessing the Occurrence of Major Adverse Cardiovascular Events (MACE) in Overweight and Obese Subjects With Cardiovascular Risk Factors Receiving Naltrexone SR/Bupropion SR Terminated NCT01601704 Phase 3 NB32;PBO
3 Effects of Stress Reduction on Eating, Fat Distribution, and Cell Aging Among Overweight Women Completed NCT01250509 Phase 2
4 Clinical Protocol to Investigate the Efficacy of Amlexanox vs. Placebo for Treatment of Glucose and Lipid Abnormalities in Obese Type 2 Diabetics Completed NCT01975935 Phase 2 Amlexanox;Placebo
5 A Double-Blind, Randomised, Placebo-Controlled Dose Escalation Study to Assess the Safety, Tolerability and Efficacy of Single and Multiple Doses of PP 1420 in Healthy Subjects. Terminated NCT02221765 Phase 1, Phase 2 PP1420;Placebo
6 Evaluation of the BALANCE System in Type 2 Diabetic Patients Completed NCT00872846 Phase 1
7 Pilot Study of the Metabolic Effects of Betahistine Hydrochloride in Overweight Women Completed NCT00459992 Phase 1 Betahistine Hydrochloride
8 Effects of Nutritional Preconditioning on the Nutritional Status of Patients Undergoing Major General Surgeries and Subsequent Operative Outcomes Not yet recruiting NCT03692507 Phase 1
9 The Effect of Different Macronutrients on Gastrointestinal Hormone Secretion After Gastric Bypass Operation Unknown status NCT02372526
10 How Quickly Can the Effects of Excessive Caloric Intake on Insulin Resistance be Reversed? Unknown status NCT02505958
11 Association of Early Life Nutritional Related Exposures and Long-term Health and Cognitive Development Outcomes in Adolescents in Northeast, Thailand Unknown status NCT01979770
12 Energy Expenditure and Sleep in Response to Protein/Carbohydrate and Fat Ratio Unknown status NCT01551238
13 Baby-STOPP: Targeted Obesity Prevention Directed to Overweight Parents With Young Children Unknown status NCT02409875
14 The Influence of Obesity on Oocyte Functioning and Fertilization, Cumulus and Granulosa Functioning and Metabolic Factors. Unknown status NCT01945671
15 Non-alcoholic Fatty Liver Disease (NAFLD) in Overweight and Obese People Under Nutritional and Lifestyle Follow-up: a Randomized Controlled Trial Unknown status NCT03183193
16 Adaptation of Lipid and Energy Metabolism During a Lipid Overnutrition in Constitutional Thinness Completed NCT01224561
17 ChildObesity180 - Social Marketing Campaign to Encourage Healthful Eating in Restaurants for Children Completed NCT03422926
18 Acute Effects of Glucose Dependent Insulinotropic Polypeptide (GIP) on Subcutaneous Adipose Tissue Completed NCT00774488
19 Effect of Metabolic Variations Upon the Activity of the Neuroendocrine Reproductive Axis in Normal Female Volunteers Completed NCT02233283
20 Nutritional Status Among naïve HIV-infected Patients and HIV-infected Patients Receiving Highly Active Antiretroviral Therapy Completed NCT01899157
21 Effect of a Low-Carbohydrate Mediterranean Diet or Low-Fat Diet in Newly-Diagnosed Type 2 Diabetic Patients Completed NCT00725257
22 The Survey About Resting Metabolic Rate and Its Related Factors in Terminal Patients Completed NCT00208013
23 Severe Insulin Resistance in Patients With Type 2 Diabetes: Mechanisms Behind Insulin Resistance. Completed NCT00654056 Actrapid (human insulin)
24 Community Translation of a Lifestyle Intervention to Improve Health in Diabetes Completed NCT01435603
25 A Psychoeducational Intervention Model in Nutrition to Improve Nutritional Status in a Pilot Low Resource Population in the City of Saltillo, Coahuila Mexico. Completed NCT02258802
26 Attenuating the Micronutrient Malnutrition of Overnutrition (AMMO) Completed NCT02239198
27 Short-term Effect of the Intake of Moderately High-protein, Low-glycemic Load Products on Anthropometrical, Glucose Metabolism and Lipid Metabolism Biomarkers, in Type-2 Diabetes Patients Completed NCT01264523
28 A Longitudinal Study to Assess if the Effectiveness of a Preschool Nutrition and Physical Activity Program is Sustained in Elementary School Completed NCT01937481
29 Clinical Investigation on the Safety of Avocado Pulp Lipids Completed NCT03898505 Early Phase 1
30 A Psychoeducational Intervention Model in Nutrition to Improve Nutritional Status in 15 Low Resource Populations Through a Network of Food Banks in Mexico. Completed NCT02914002
31 A 6-month Family-based, Intense Lifestyle Intervention Program and Carotenoid Supplementation for Children With Obesity: A Pilot Study Completed NCT02060279
32 Healthy Babies Through Infant Centered Feeding Completed NCT01816516
33 Randomized Controlled Trial of a Sugar-Sweetened Beverage Intervention in Overweight Mothers and Their Children Ages 3-5 Completed NCT02098902
34 The Role of Physical Activity During Pregnancy on Metabolic Function, Inflammation, and Maternal and Neonatal Outcomes Completed NCT03504319
35 A Pragmatic Family-Centered Approach to Childhood Obesity Treatment Recruiting NCT03843424
36 The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity Recruiting NCT00342732
37 Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care Active, not recruiting NCT03003403
38 Maternal Obesity, Breast Milk Composition, and Infant Growth Active, not recruiting NCT03301753
39 Effects of Flavanol-rich Dark Chocolate Consumption on Metabolic Profiles Among Obese Not yet recruiting NCT04347304
40 Scientific Foundations for Developing and Validating Food-based Dietary Guidelines and a Healthy Eating Index for Ethiopia Not yet recruiting NCT03394963
41 Measurement of Energy Metabolism in Infants: BabyEE Pilot Suspended NCT02683473
42 The Role of Ceramides in Skeletal Muscle Withdrawn NCT03731598
43 The Role of GLP-1 in Satiety Perception in Humans Withdrawn NCT01152333 Exendin-(9-39) Acetate;Saline 0.9%

Search NIH Clinical Center for Overnutrition

Cochrane evidence based reviews: overnutrition

Genetic Tests for Overnutrition

Anatomical Context for Overnutrition

MalaCards organs/tissues related to Overnutrition:

Liver, Skeletal Muscle, Brain, Adipocyte, Breast, Heart, Thyroid

Publications for Overnutrition

Articles related to Overnutrition:

(show top 50) (show all 1425)
# Title Authors PMID Year
Concerned and Conscious, but DefenselessThe intersection of gender and generation in child malnutrition in Indonesia: a qualitative grounded theory study. 61
32370625 2020
Prolonged overnutrition with fructose or fat induces metabolic derangements in rats by disrupting the crosstalk between the hypothalamus and periphery: Possible amelioration with fenofibrate. 61
32360834 2020
Epigenetic Transgenerational Inheritance of Obesity Susceptibility. 61
32521235 2020
Oxygen therapy alleviates hepatic steatosis by inhibiting hypoxia-inducible factor-2α. 61
32369776 2020
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells. 61
32332159 2020
Short-term High-fat Overfeeding Does Not Induce NF-κB Inflammatory Signaling in Subcutaneous White Adipose Tissue. 61
32232380 2020
Maternal overnutrition impairs offspring's insulin sensitivity: A systematic review and meta-analysis. 61
32567808 2020
Exposure to low doses of Dechlorane Plus promotes adipose tissue dysfunction and glucose intolerance in male mice. 61
32556108 2020
The Co-Occurrence of Overweight and Micronutrient Deficiencies or Anemia among Women of Reproductive Age in Malawi. 61
32271925 2020
Early Nutrition eAcademy Southeast Asia e-Learning for Enhancing Knowledge on Nutrition during the First 1000 Days of Life. 61
32570814 2020
The Role of Vegetable Genetic Resources in Nutrition Security and Vegetable Breeding. 61
32545299 2020
Changes in Expression of the Genes for the Leptin Signaling in Hypothalamic-Pituitary Selected Areas and Endocrine Responses to Long-Term Manipulation in Body Weight and Resistin in Ewes. 61
32545900 2020
Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. 61
32516139 2020
The effects of dietary fatty acids in the physiological outcomes of maternal high-fat diet on offspring energy homeostasis in mice. 61
31556363 2020
Nutrition during childhood cancer treatment: current understanding and a path for future research. 61
32061318 2020
Dietary Fat and Cancer-Which Is Good, Which Is Bad, and the Body of Evidence. 61
32526973 2020
The differential effect of maternal dietary patterns on quantiles of Birthweight. 61
32571268 2020
Role of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Oxidative Stress-Associated Metabolic Diseases. 61
32077785 2020
Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice. 61
32439824 2020
The neuronal (pro)renin receptor and astrocyte inflammation in the central regulation of blood pressure and blood glucose in mice fed a high-fat diet. 61
32228320 2020
An assessment of nutritional status in children of rural, northern KwaZulu-Natal province. 61
32501037 2020
Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice. 61
32444826 2020
Impact of interventions to reduce overnutrition on healthcare costs related to obesity and type 2 diabetes: a systematic review. 61
31769843 2020
Food Insecurity and Pediatric Malnutrition Related to Under- and Overweight in the United States: An Evidence Analysis Center Systematic Review. 61
32402759 2020
An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation. 61
32437306 2020
Cellular Contributors to Hypothalamic Inflammation in Obesity. 61
32392909 2020
Dietary Fat and Sugar Differentially Affect β-Adrenergic Stimulation of Cardiac ERK and AKT Pathways in C57BL/6 Male Mice Subjected to High-Calorie Feeding. 61
31950177 2020
In the Footsteps of Wilbur Olin Atwater: The Atwater Lecture for 2019. 61
31925422 2020
An oxide transport chain essential for balanced insulin action. 61
32171979 2020
Nutrition in Patients with Idiopathic Pulmonary Fibrosis: Critical Issues Analysis and Future Research Directions. 61
32316662 2020
Milk Fat Globule-EGF Factor 8 improves Hepatic Steatosis and Inflammation. 61
32297339 2020
Examining Mid-Upper Arm Circumference Malnutrition z-Score Thresholds. 61
31175704 2020
Maternal stressors and the developmental origins of neuropsychiatric risk. 61
32084515 2020
Spatial-temporal trends and risk factors for undernutrition and obesity among children (<5 years) in South Africa, 2008-2017: findings from a nationally representative longitudinal panel survey. 61
32273314 2020
Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction. 61
32325263 2020
Are dietary intake and nutritional status influenced by gender? The pattern of dietary intake in Lao PDR: a developing country. 61
32278347 2020
Double Burden of Malnutrition in the Asia-Pacific Region-A Systematic Review and Meta-analysis. 61
32175706 2020
Social Determinants of Placental Health and Future Disease Risks for Babies. 61
32008662 2020
India: country report on children's environmental health. 61
31926103 2020
Identification of a New Chemotype of Anti-Obesity Compounds by Ensemble Screening. 61
32149264 2020
Complex epigenetic patterns in cerebellum generated after developmental exposure to trichloroethylene and/or high fat diet in autoimmune-prone mice. 61
31894794 2020
The influence of nutrition on clinical outcomes in children with cancer. 61
32134218 2020
High salt intake during puberty leads to cardiac remodelling and baroreflex impairment in lean and obese male Wistar rats. 61
31831096 2020
[Gallstone disease - interdisciplinary treatment]. 61
32120403 2020
Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis. 61
31076404 2020
Proteostasis in thermogenesis and obesity. 61
32061163 2020
"INTERGROWTH21st vs customized fetal growth curves in the assessment of the neonatal nutritional status: a retrospective cohort study of gestational diabetes". 61
32131758 2020
Tissue-specific analysis of lipid species in Drosophila during overnutrition by UHPLC-MS/MS and MALDI-MSI. 61
31900315 2020
Comprehensive physical fitness and high blood pressure in children and adolescents: A national cross-sectional survey in China. 61
32197926 2020
SIRT6 cooperates with SIRT5 to regulate bovine preadipocyte differentiation and lipid metabolism via the AMPKα signaling pathway. 61
31926163 2020

Variations for Overnutrition

Expression for Overnutrition

Search GEO for disease gene expression data for Overnutrition.

Pathways for Overnutrition

GO Terms for Overnutrition

Cellular components related to Overnutrition according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.44 SERPINA3 MIR378A MIR21 MIR199A1 MIR155 MIR126
2 extracellular vesicle GO:1903561 9.26 MIR21 MIR126 MIR122 MIR103A1

Biological processes related to Overnutrition according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.84 MIR21 LEP FGF1 ADIPOQ
2 positive regulation of inflammatory response GO:0050729 9.8 MIR21 MIR155 MIR126
3 circadian rhythm GO:0007623 9.8 LEP AGRP ADIPOQ
4 gene silencing by miRNA GO:0035195 9.8 MIR378A MIR21 MIR199A1 MIR155 MIR126 MIR122
5 response to nutrient GO:0007584 9.77 PPARG LEP ADIPOQ
6 response to nutrient levels GO:0031667 9.76 PPARG LEP ADIPOQ
7 glucose homeostasis GO:0042593 9.76 PPARG LEP INS ADIPOQ
8 glucose metabolic process GO:0006006 9.73 LEP INS ADIPOQ
9 positive regulation of endothelial cell migration GO:0010595 9.72 MIR21 MIR199A1 FGF1
10 cellular response to insulin stimulus GO:0032869 9.71 PPARG MIR103A1 LEP ADIPOQ
11 miRNA mediated inhibition of translation GO:0035278 9.67 MIR378A MIR21 MIR155 MIR103A1
12 activation of protein kinase B activity GO:0032148 9.65 MIR21 INS FGF1
13 positive regulation of connective tissue replacement GO:1905205 9.63 MIR199A1 MIR155
14 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.62 PPARG ADIPOQ
15 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.62 MIR21 MIR126 LEP INS
16 adult feeding behavior GO:0008343 9.61 LEP AGRP
17 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.61 MIR199A1 MIR155
18 positive regulation of sprouting angiogenesis GO:1903672 9.61 MIR155 MIR126 FGF1
19 negative regulation of cartilage development GO:0061037 9.59 MIR21 LEP
20 negative regulation of regulatory T cell differentiation GO:0045590 9.58 MIR21 MIR155
21 negative regulation of acute inflammatory response GO:0002674 9.57 PPARG INS
22 positive regulation of angiogenesis GO:0045766 9.55 MIR378A MIR21 MIR199A1 MIR126 FGF1
23 positive regulation of necroptotic process GO:0060545 9.52 MIR155 MIR103A1
24 regulation of brown fat cell differentiation GO:0090335 9.51 LEP FTO
25 positive regulation of fatty acid metabolic process GO:0045923 9.49 PPARG ADIPOQ
26 negative regulation of inflammatory response GO:0050728 9.35 SOCS3 PPARG MIR155 MIR126 ADIPOQ
27 positive regulation of protein kinase B signaling GO:0051897 9.1 MIR21 MIR199A1 MIR126 LEP INS FGF1

Molecular functions related to Overnutrition according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.1 MIR378A MIR21 MIR199A1 MIR155 MIR126 MIR103A1

Sources for Overnutrition

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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