MCID: OXR001
MIFTS: 20

Oxirane Allergy

Categories: Immune diseases

Aliases & Classifications for Oxirane Allergy

MalaCards integrated aliases for Oxirane Allergy:

Name: Oxirane Allergy 12 15
Ethylene Oxide Allergy 12
Eto Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040082

Summaries for Oxirane Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger oxirane.

MalaCards based summary : Oxirane Allergy, also known as ethylene oxide allergy, is related to cefaclor allergy and chlorhexidine allergy. An important gene associated with Oxirane Allergy is ALB (Albumin), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Immune response Role of DAP12 receptors in NK cells.

Related Diseases for Oxirane Allergy

Diseases related to Oxirane Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 100)
# Related Disease Score Top Affiliating Genes
1 cefaclor allergy 10.3 CD63 ALB
2 chlorhexidine allergy 10.3 ENPP3 CD63
3 crab allergy 10.3 ENPP3 CD63
4 dermatographia 10.2 ENPP3 CD63
5 nut allergy 10.2 ENPP3 CD63
6 capillary disease 10.2 IL3RA ALB
7 legume allergy 10.2 ENPP3 CD63
8 fruit allergy 10.2 ENPP3 CD63
9 capillary leak syndrome 10.2 IL3RA ALB
10 orthostatic proteinuria 10.2 B2M ALB
11 ige responsiveness, atopic 10.2
12 non-secretory myeloma 10.2 B2M ALB
13 hydrops, lactic acidosis, and sideroblastic anemia 10.2 KNG1 ALB
14 pyuria 10.2 B2M ALB
15 diamond-blackfan anemia 3 10.2 B2M ALB
16 alveolar periostitis 10.2 PF4 KNG1
17 immunodeficiency 43 10.2 B2M ALB
18 scalp-ear-nipple syndrome 10.2 ENPP3 CD63
19 chronic pyelonephritis 10.2 B2M ALB
20 pulmonary artery disease 10.1 PF4 ALB
21 pyelitis 10.1 B2M ALB
22 eosinophilic gastroenteritis 10.1 IL3 ALB
23 acute kidney tubular necrosis 10.1 B2M ALB
24 amyloidosis, hereditary, transthyretin-related 10.1 B2M ALB
25 danubian endemic familial nephropathy 10.1 B2M ALB
26 proteinuria, chronic benign 10.1 B2M ALB
27 renal hypertension 10.1 KNG1 ALB
28 plasma protein metabolism disease 10.1 B2M ALB
29 intermittent claudication 10.1 PF4 ALB
30 drug allergy 10.1 ENPP3 CD63 ALB
31 pain agnosia 10.1 KNG1 ALB
32 acute apical periodontitis 10.1 KNG1 IL3
33 respiratory allergy 10.1 IL3 ENPP3
34 akinetopsia 10.1 KNG1 B2M
35 agnosia 10.1 KNG1 ALB
36 phenytoin allergy 10.1 KNG1 IL3
37 hypersensitivity vasculitis 10.1 FCGR3B ALB
38 syphilis 10.1 B2M ALB
39 von willebrand's disease 10.0 PF4 CD63
40 neural tube defects 10.0
41 exanthem 10.0
42 c1 inhibitor deficiency 10.0
43 myelomeningocele 10.0
44 osteomyelitis 10.0
45 angioedema 10.0
46 hypereosinophilic syndrome 10.0
47 nasal cavity disease 10.0 IL3 ALB
48 physical urticaria 10.0 KNG1 ENPP3 CD63
49 blood protein disease 10.0 B2M ALB
50 peripheral vascular disease 10.0 PF4 KNG1 ALB

Graphical network of the top 20 diseases related to Oxirane Allergy:



Diseases related to Oxirane Allergy

Symptoms & Phenotypes for Oxirane Allergy

Drugs & Therapeutics for Oxirane Allergy

Search Clinical Trials , NIH Clinical Center for Oxirane Allergy

Genetic Tests for Oxirane Allergy

Anatomical Context for Oxirane Allergy

Publications for Oxirane Allergy

Articles related to Oxirane Allergy:

# Title Authors PMID Year
1
Mediation of hypersensitivity reactions during hemodialysis by IgE antibodies against ethylene oxide. 61
3297007 1987
2
IgE against ethylene oxide-altered human serum albumin (ETO-HSA) as an etiologic agent in allergic reactions of hemodialysis patients. 61
3593052 1987

Variations for Oxirane Allergy

Expression for Oxirane Allergy

Search GEO for disease gene expression data for Oxirane Allergy.

Pathways for Oxirane Allergy

Pathways related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.18 PF4 KNG1 IL3RA IL3 CD63 ALB
2
Show member pathways
11.97 IL3 FCGR3B FCGR3A
3 11.77 IL3 ENPP3 CD63 B2M
4
Show member pathways
11.54 IL3RA IL3 ENPP3
5
Show member pathways
11.28 IL3RA IL3

GO Terms for Oxirane Allergy

Cellular components related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 PF4 KNG1 IL3 CD63 B2M ALB
2 extracellular exosome GO:0070062 9.7 KNG1 FCGR3B FCGR3A ENPP3 CD63 B2M
3 external side of plasma membrane GO:0009897 9.56 IL3RA FCGR3A ENPP3 B2M
4 endoplasmic reticulum lumen GO:0005788 9.54 KNG1 B2M ALB
5 extracellular region GO:0005576 9.28 PF4 KNG1 IL3 FCGR3B FCGR3A ENPP3
6 platelet alpha granule lumen GO:0031093 9.13 PF4 KNG1 ALB

Biological processes related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.54 PF4 IL3RA IL3
2 cellular protein metabolic process GO:0044267 9.43 KNG1 B2M ALB
3 immune response GO:0006955 9.35 PF4 IL3 FCGR3B FCGR3A B2M
4 regulation of immune response GO:0050776 9.33 FCGR3B FCGR3A B2M
5 retina homeostasis GO:0001895 9.32 B2M ALB
6 platelet degranulation GO:0002576 8.92 PF4 KNG1 CD63 ALB

Molecular functions related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 8.62 FCGR3B FCGR3A

Sources for Oxirane Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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