MCID: OXR001
MIFTS: 21

Oxirane Allergy

Categories: Immune diseases

Aliases & Classifications for Oxirane Allergy

MalaCards integrated aliases for Oxirane Allergy:

Name: Oxirane Allergy 12 15
Ethylene Oxide Allergy 12
Eto Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0040082

Summaries for Oxirane Allergy

Disease Ontology : 12 A drug allergy that has allergic trigger oxirane.

MalaCards based summary : Oxirane Allergy, also known as ethylene oxide allergy, is related to hydrops, lactic acidosis, and sideroblastic anemia and apricot allergy. An important gene associated with Oxirane Allergy is RUNX1T1 (RUNX1 Partner Transcriptional Co-Repressor 1), and among its related pathways/superpathways are Pathways in cancer and Response to elevated platelet cytosolic Ca2+. Affiliated tissues include nk cells and myeloid.

Related Diseases for Oxirane Allergy

Diseases related to Oxirane Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 hydrops, lactic acidosis, and sideroblastic anemia 30.3 KNG1 ALB
2 apricot allergy 10.3 TMEM189 ENPP3
3 melon allergy 10.3 ENPP3 ALB
4 lymphocele 10.3 ERVMER34-1 ALB
5 wheat allergy 10.3 TMEM189 ENPP3
6 paralytic ileus 10.3 ERVMER34-1 ALB
7 common bile duct disease 10.3 ERVMER34-1 ALB
8 cefaclor allergy 10.3 CD63 ALB
9 rocuronium allergy 10.3 TMEM189 CD63
10 cecal disease 10.2 ERVMER34-1 ALB
11 ige responsiveness, atopic 10.2
12 eosinophilic gastroenteritis 10.1 IL3 ALB
13 intermediate coronary syndrome 10.1 PF4 ALB
14 fruit allergy 10.0 TMEM189 ENPP3 CD63
15 conjunctival disease 10.0 TMEM189 ALB
16 egg allergy 10.0 TMEM189 ENPP3 CD63
17 nut allergy 10.0 TMEM189 ENPP3 CD63
18 neural tube defects 10.0
19 exanthem 10.0
20 c1 inhibitor deficiency 10.0
21 myelomeningocele 10.0
22 osteomyelitis 10.0
23 angioedema 10.0
24 hypereosinophilic syndrome 10.0
25 nasal cavity disease 10.0 TMEM189 IL3 ALB
26 nose disease 10.0 TMEM189 IL3 ALB
27 pulmonary artery disease 10.0 PF4 ALB
28 autonomic nervous system disease 9.9 KNG1 ALB
29 hypersensitivity vasculitis 9.9 FCGR3B ALB
30 pleural disease 9.9 KNG1 ERVMER34-1 ALB
31 blood coagulation disease 9.9 PF4 IL3 ALB
32 thrombocytosis 9.8 PF4 IL3 ALB
33 drug allergy 9.8 TMEM189 ENPP3 CD63 ALB
34 blood platelet disease 9.8 PF4 IL3 ALB
35 physical urticaria 9.8 KNG1 ENPP3 CD63
36 transient neonatal neutropenia 9.8 FCGR3B FCGR3A
37 chronic nk-cell lymphocytosis 9.8 FCGR3B FCGR3A
38 megakaryocytic leukemia 9.8 PF4 IL3RA IL3
39 cd3zeta deficiency 9.8 FCGR3B FCGR3A
40 peripheral vascular disease 9.8 PF4 KNG1 ALB
41 aggressive nk-cell leukemia 9.7 FCGR3B FCGR3A
42 renal hypertension 9.7 KNG1 ALB
43 iga glomerulonephritis 9.7 PF4 ALB
44 cardiomyopathy, dilated, 1c, with or without left ventricular noncompaction 9.7 FCGR3B FCGR3A
45 essential thrombocythemia 9.7 PF4 IL3 CD63
46 coronary artery anomaly 9.6 PF4 KNG1 ALB
47 autoimmune disease of blood 9.6 FCGR3B FCGR3A
48 diphtheria 9.6 IL3RA IL3 CD63 ALB
49 poliomyelitis 9.6 FCGR3B FCGR3A
50 amoxicillin allergy 9.6 IL3RA IL3 ENPP3 CD63

Graphical network of the top 20 diseases related to Oxirane Allergy:



Diseases related to Oxirane Allergy

Symptoms & Phenotypes for Oxirane Allergy

Drugs & Therapeutics for Oxirane Allergy

Search Clinical Trials , NIH Clinical Center for Oxirane Allergy

Genetic Tests for Oxirane Allergy

Anatomical Context for Oxirane Allergy

MalaCards organs/tissues related to Oxirane Allergy:

40
Nk Cells, Myeloid

Publications for Oxirane Allergy

Articles related to Oxirane Allergy:

# Title Authors PMID Year
1
IgE against ethylene oxide-altered human serum albumin (ETO-HSA) as an etiologic agent in allergic reactions of hemodialysis patients. 61
3593052 1987
2
Mediation of hypersensitivity reactions during hemodialysis by IgE antibodies against ethylene oxide. 61
3297007 1987

Variations for Oxirane Allergy

Expression for Oxirane Allergy

Search GEO for disease gene expression data for Oxirane Allergy.

Pathways for Oxirane Allergy

Pathways related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.28 RUNX1T1 KNG1 IL3RA IL3
2
Show member pathways
12.18 PF4 KNG1 IL3RA IL3 CD63 ALB
3 11.77 RUNX1T1 IL3 ENPP3 CD63
4
Show member pathways
11.54 IL3RA IL3 ENPP3
5
Show member pathways
11.35 IL3RA IL3

GO Terms for Oxirane Allergy

Cellular components related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.63 KNG1 FCGR3B FCGR3A ENPP3 CD63 ALB
2 extracellular region GO:0005576 9.23 PF4 KNG1 IL3 FCGR3B ERVMER34-1 ENPP3
3 platelet alpha granule lumen GO:0031093 9.13 PF4 KNG1 ALB

Biological processes related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.35 PF4 IL3 FCGR3B FCGR3A ENPP3
2 platelet degranulation GO:0002576 8.92 PF4 KNG1 CD63 ALB

Molecular functions related to Oxirane Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 8.62 FCGR3B FCGR3A

Sources for Oxirane Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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