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Pain Agnosia

Categories: Mental diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Pain Agnosia

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MalaCards integrated aliases for Pain Agnosia:

Name: Pain Agnosia 12 15
Analgesia 12 15

Classifications:

MalaCards categories:
Anatomical: Mental diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:0060145
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Summaries for Pain Agnosia

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Disease Ontology : 12 An agnosia that is a loss of the ability to perceive and process pain.

MalaCards based summary : Pain Agnosia, also known as analgesia, is related to anxiety and constipation. An important gene associated with Pain Agnosia is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Signaling by GPCR and Peptide ligand-binding receptors. The drugs Dexmedetomidine and Dezocine have been mentioned in the context of this disorder. Affiliated tissues include lung, brain and bone, and related phenotypes are behavior/neurological and adipose tissue

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Related Diseases for Pain Agnosia

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Diseases related to Pain Agnosia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 366)
# Related Disease Score Top Affiliating Genes
1 anxiety 30.4 CNR1 OPRL1 OXT
2 constipation 30.2 CCK OPRM1 TAC1
3 morphine dependence 30.1 CCK OPRM1 TRPV1
4 bone cancer 30.0 CNR1 PDYN TRPV1
5 opioid addiction 30.0 CCK OPRM1 PNOC
6 opiate dependence 29.7 OPRM1 PDYN POMC
7 withdrawal disorder 29.7 CNR1 HTR7 OPRM1 PDYN POMC
8 migraine with or without aura 1 29.7 CNR1 HTR7 IER3IP1 TAC1 TRPV1
9 amnestic disorder 29.6 CNR1 HTR7 PDYN
10 opioid abuse 29.6 CCK OPRL1 OPRM1 PDYN
11 irritable bowel syndrome 29.5 CCK HTR7 TAC1 TRPV1
12 drug dependence 29.5 CNR1 OPRL1 OPRM1 PDYN POMC
13 agnosia 27.6 AP1M2 AP2M1 CCK CNR1 HTR7 IER3IP1
14 increased analgesia from kappa-opioid receptor agonist, female-specific 12.2
15 chronic pain requiring intraspinal analgesia 12.0
16 neuropathy, hereditary sensory and autonomic, type v 11.6
17 marsili syndrome 11.2
18 indifference to pain, congenital, autosomal recessive 11.2
19 congenital insensitivity to pain with hyperhidrosis 11.0
20 congenital insensitivity to pain with severe intellectual disability 11.0
21 leiomyoma cutis 10.3 TAC1 TRPV1
22 cyclic vomiting syndrome 10.3 CNR1 OPRM1
23 myofascial pain syndrome 10.3 POMC TAC1
24 autoimmune encephalitis 10.3 CNR1 TRPV1
25 retrograde amnesia 10.3 PDYN POMC
26 sick building syndrome 10.2 POMC TRPV1
27 somatoform disorder 10.2 OPRM1 TAC1 TRPV1
28 postmenopausal atrophic vaginitis 10.2 OXT POMC
29 cocaine dependence 10.2 OPRM1 PDYN POMC
30 stereotypic movement disorder 10.2 CCK TAC1
31 epicondylitis 10.2 LIPN TAC1
32 trigeminal nerve disease 10.2 LIPN TAC1 TRPV1
33 bronchial disease 10.2 IER3IP1 TAC1 TRPV1
34 pancreas disease 10.2 CCK POMC TRPV1
35 shipyard eye 10.2 PDYN PSENEN
36 glucose metabolism disease 10.2 IER3IP1 POMC TRPV1
37 horner's syndrome 10.2
38 overnutrition 10.2 CNR1 POMC TRPV1
39 nasal cavity adenocarcinoma 10.2 CCK PDYN
40 acquired metabolic disease 10.2 IER3IP1 POMC TRPV1
41 functional gastric disease 10.2 CCK HTR7 TRPV1
42 substance dependence 10.2 CNR1 OPRM1 POMC
43 anismus 10.2 OXT TAC1
44 epidural abscess 10.2
45 diverticulitis of colon 10.2 CNR1 TRPV1
46 cutaneous solitary mastocytoma 10.2 PDYN POMC
47 eating disorder 10.2 CCK CNR1 POMC
48 separation anxiety disorder 10.2 HTR7 OPRM1 OXT
49 premenstrual tension 10.2 LIPN OXT POMC
50 pectus excavatum 10.2

Graphical network of the top 20 diseases related to Pain Agnosia:



Diseases related to Pain Agnosia
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Symptoms & Phenotypes for Pain Agnosia

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MGI Mouse Phenotypes related to Pain Agnosia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.7 CCK CNR1 HTR7 OPRL1 OPRM1 OXT
2 adipose tissue MP:0005375 9.63 CNR1 OPRM1 OXT PDYN POMC TRPV1
3 integument MP:0010771 9.32 CNR1 HTR7 OPRL1 OPRM1 OXT PDYN
Sources

Drugs & Therapeutics for Pain Agnosia

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Drugs for Pain Agnosia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 714)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 113775-47-6 68602 5311068
2
Dezocine Approved, Investigational Phase 4,Not Applicable 53648-55-8 3033053 40841
3
Flurbiprofen Approved, Investigational Phase 4,Not Applicable 5104-49-4 3394
4
Ropivacaine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 84057-95-4 175805 71273
5
Levobupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 27262-47-1 92253
6
Bupivacaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
7
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 437-38-7 3345
8
Nalbuphine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 20594-83-6 5311304 5360630
9
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 6740-88-1 3821
10
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
11
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1177-87-3
12
Tramadol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 27203-92-5 33741
13
Ketorolac Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 66635-83-4, 74103-06-3 3826
14
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 57-27-2 5288826
15 Nefopam Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 13669-70-0
16
Sufentanil Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 56030-54-7 41693
17
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
18
Clonidine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 4205-90-7 2803
19
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 329-65-7 838
20
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 51-43-4 5816
21
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Not Applicable 2921-57-5
22
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
23
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
24
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 302-25-0
25
Pentazocine Approved, Vet_approved Phase 4 359-83-1 441278
26
Palonosetron Approved, Investigational Phase 4,Not Applicable 119904-90-4, 135729-61-2, 135729-56-5 148211
27
Cisatracurium Approved Phase 4,Early Phase 1,Not Applicable 96946-41-7
28
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59467-70-8 4192
29
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 2078-54-8 4943
30
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
31
Remifentanil Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 132875-61-7 60815
32 tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
33
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
34
Hydromorphone Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 466-99-9 5284570
35
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 76-42-6 5284603
36
Sevoflurane Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable,Early Phase 1 28523-86-6 5206
37
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 7487-88-9 24083
38
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 60142-96-3 3446
39
Prilocaine Approved Phase 4,Phase 2,Phase 3,Not Applicable 721-50-6 4906
40
Mineral oil Approved, Vet_approved Phase 4,Phase 3 8042-47-5
41
Benzoic Acid Approved, Investigational Phase 4 65-85-0 243
42
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 169590-42-5 2662
43
Dextromethorphan Approved Phase 4,Phase 2,Not Applicable 125-71-3 5360696 5362449
44
Pantoprazole Approved Phase 4 102625-70-7 4679
45
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 93-14-1 3516
46
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 148553-50-8 5486971
47
Codeine Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 76-57-3 5284371
48
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 22204-53-1 1302 156391
49
Chloroprocaine Approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 133-16-4 8612
50
Procaine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 59-46-1 4914

Interventional clinical trials:

(show top 50) (show all 4179)
# Name Status NCT ID Phase Drugs
1 Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia Unknown status NCT03014713 Phase 4 Dezocine;Flubiprofen;Dexmedetomidine
2 Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine Unknown status NCT01158586 Phase 4 Levobupivacaine
3 Ketamine and Postoperative Analgesia in Children Unknown status NCT00200564 Phase 4 ketamine
4 Effects of Transverse Abdominis Plane Block Guided by Ultrasound on the Postoperative Analgesia and Quality of Lives Among the Patients Undergo Inguinal Hernia Repair Unknown status NCT02292095 Phase 4
5 Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic Unknown status NCT01543165 Phase 4 Ketorolac and nefopam balanced analgesia;Balanced analgesia using ketorolac and morphine;Pain control with single analgesics (ketorolac)
6 Epidural Analgesia for Pancreatitis (Epipan Study) Unknown status NCT02126332 Phase 4
7 Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty Unknown status NCT02603900 Phase 4 ropivacaine;bupivacaine
8 Continuous Femoral Nerve Block Versus Local-wound Infiltration Analgesia For Patients Receiving Total Knee Arthroplasty --- A Randomized Controlled Trial Unknown status NCT02284620 Phase 4
9 Analgesia After Total Knee Arthroplasty Unknown status NCT00869037 Phase 4 Periarticular Injection;CFNB + Posterior Capsular Injection
10 Comparison of Three Kinds of Postoperative Analgesia After Total Knee Arthroplasty Unknown status NCT02094339 Phase 4 ropivacaine;ropivacaine;opioid
11 The Efficacy and Optimal Dose of Sufentanil in Patient Controlled Analgesia After Moderate Surgery Unknown status NCT02503826 Phase 4 Sufentanil;Sufentanil;Sufentanil;Midazolam;propofol;cisatracurium
12 Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean Section Unknown status NCT01465191 Phase 4 Morphine
13 Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery Unknown status NCT02552459 Phase 4 Sufentanil;dexmedetomidine 1;dexmedetomidine 2;dexmedetomidine 3
14 Dexamethasone or Clonidine as Adjuncts to Ropivacaine for Caudal Analgesia on Analgesia Duration in Children Unknown status NCT02773602 Phase 4 Dexamethasone;Clonidine;Normal Saline
15 Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery Unknown status NCT00532662 Phase 4 S(+)-ketamine
16 Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy Unknown status NCT02523846 Phase 4 morphine
17 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
18 Interest of a Bi-truncal Nerve Block (Femoral + Sciatic) Extended, Systematically Associated With General Anesthesia, in the Femoropopliteal Bypass: Study of Post-operative Analgesia and Peripheral Circulation Downstream Unknown status NCT01785693 Phase 4 levobupivacaine, clonidine
19 Comparison of Two Kinds of Postoperative Analgesia After Amputation Unknown status NCT02114463 Phase 4 ropivacaine;flurbiprofen
20 Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA) Unknown status NCT01281891 Phase 4 LIA;I/T morphine
21 Home Infusors for Analgesia After Foot Surgery Unknown status NCT00600899 Phase 4
22 Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy Unknown status NCT01698203 Phase 4 ropivacaine 0.75% - device : wound catheter Silverâ„¢ 19 cm and Easypumpâ„¢ 400 mL (BBraun);Placebo;ropivacaine 0.2% - device : wound catheter Silverâ„¢ 19 cm and Easypumpâ„¢ 400 mL (BBraun)
23 Comparison of Efficacy and Safety of the Postoperative Analgesia Methods Unknown status NCT02929147 Phase 4 Morphine;Dexketoprofen;Placebo
24 VPIA Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration Unknown status NCT02733835 Phase 4 Remifentanil
25 the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation Unknown status NCT02635802 Phase 4 Remifentanil;Lidocaine;Remifentanil+Lidocaine;Midazolam
26 Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section Unknown status NCT02279628 Phase 4 Ropivacaine;Morphine
27 PIB Versus CI Through a Popliteal Sciatic Nerve Catheter for Analgesia Following Major Ankle Surgery Unknown status NCT02707874 Phase 4 CI 0.2% ropivacaine;PIB 0.2% ropivacaine
28 Controlled Release of Oxycodone 10 mg In Pre-Medication For The Post Operative Analgesia In Elective Laparoscopic Bilateral Inguinal Hernia And Elective Laparoscopic Cholecystectomy Unknown status NCT00480142 Phase 4 Oxycodone 10 mg
29 The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip Replacement Unknown status NCT01312077 Phase 4 Levobupivacaine;Intrathecal morphine
30 A Comparison of Two Anaesthetic Methods of Protecting Heart Tissue During Cardiac Surgery Unknown status NCT00244283 Phase 4 Sevoflurane
31 Effect of Intraperitoneal Nebulisation of Magnesium Sulphate for Analgesia Following Laparoscopic Cholecystectomy Unknown status NCT01542697 Phase 4 intraperitoneal nebulisation of magnesium sulphate
32 Optimal Multimodal Analgesia in Abdominal Hysterectomy Unknown status NCT00209872 Phase 4 Gabapentin;Lidocaine;S-ketamine
33 Minimum Effective Dose (MED) & Epidural Bupivacaine Unknown status NCT02116842 Phase 4 0.1% bupivacaine;0.075% bupivacaine;40 µg fentanyl
34 Quadratus Lumborum Block for Postoperative Analgesia After Colostomy Closure Unknown status NCT02691403 Phase 4 levo-bupivacaine;normal saline
35 Fast-release Orodispersible Tramadol as Analgesia in Termination of Pregnancy by Vacuum Aspiration. Unknown status NCT02416141 Phase 4 fast release oro dispersible tramadol 50 mg
36 Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty Unknown status NCT02713490 Phase 4 EXPAREL;Bupivacaine
37 Suprascapular Nerve Block as Postoperative Analgesia After Artroscopic Shoulder Surgery Unknown status NCT02576223 Phase 4 Ropivacaine hydrochloride;Isotonic Saline
38 Ultrasound Guided Pectoral Nerve I and II Blocks in Multimodal Analgesia for Breast Surgery Unknown status NCT02672813 Phase 4
39 Obturator and Femoral Nerve Block in Patients With Hip Fracture Unknown status NCT02540837 Phase 4 Bupivacaine;Saline
40 The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Unknown status NCT02535273 Phase 4 Dexmedetomidine;Lidocaine;Low-dose Dexmedetomidine;Moderate-dose Dexmedetomidine;High-dose Dexmedetomidine;normal saline
41 Adductor Canal Block Versus Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction Arthroscopically Unknown status NCT02355093 Phase 4 ropivacaine
42 A Multicenter Study: Dexmedetomidine Combined With Sufentanil for Patient Controlled Intravenous Analgesia After Caesarean Section Unknown status NCT02741219 Phase 4 Normal saline;Dexmedetomidine;Sufentanil;Sufentanil and dexmedetomidine
43 Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice Unknown status NCT01303614 Phase 4 Lidocaine-Prilocaine cream;placebo
44 Perioperative Analgesia After Knee Arthroplasty Unknown status NCT01225484 Phase 4
45 The Effect of Analgesia Based Sedation Protocol on Brain Function of Critical Care Patients Unknown status NCT02078583 Phase 4 Fentanyl;Remifentanil;Normal saline
46 Local Infiltration Analgesia With Ropivacaine Versus Placebo in Bilateral Hip Arthroplasty Unknown status NCT00864409 Phase 4 ropivacaine 0,2%;saline.9%
47 Dexamethasone and Block Duration in Upper Extremity Unknown status NCT01756573 Phase 4 Dexamthsone;Bupivacaine
48 Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty Unknown status NCT02987920 Phase 4 Dextromethorphan;Placebo - Concentrate;Acetaminophen;Oxycodone;Celecoxib;Pantoprazole;Ketorolac;Gabapentin;Hydromorphone
49 Preventing Pain After Heart Surgery Unknown status NCT01480765 Phase 4 Pregabalin;Ketamine infusion;Placebo capsules;Placebo infusion
50 Transversus Abdominis Plane Block (TAP) for Laparoscopic Cholecystectomy Surgery Unknown status NCT02185716 Phase 4 Levobupivacaine 0.25 %;Levobupivacaine 0.5%

Search NIH Clinical Center for Pain Agnosia

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Genetic Tests for Pain Agnosia

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Anatomical Context for Pain Agnosia

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MalaCards organs/tissues related to Pain Agnosia:

41
Lung, Brain, Bone, Heart, Spinal Cord, Liver, Eye
Sources

Publications for Pain Agnosia

About this section

Articles related to Pain Agnosia:

(show top 50) (show all 978)
# Title Authors Year
1
Modification of Descending Analgesia in Aging: Critical Role of the Prefrontal Cortex. ( 30222616 )
2019
2
Withholding Urinary Catheters in Children Receiving Patient-Controlled Analgesia for Appendicitis. ( 30502234 )
2019
3
Response to McLaughlin et al regarding: "Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study". ( 30551784 )
2019
4
Bidirectional selection for high and low stress-induced analgesia affects G-protein activity. ( 30326238 )
2019
5
The impact of emergency department patient-controlled analgesia (PCA) on the incidence of chronic pain following trauma and non-traumatic abdominal pain. ( 30367688 )
2019
6
Predicting Procedure-specific Morphine Consumption of Intravenous Patient-controlled Analgesia With Random-effect Model Approach. ( 30148721 )
2019
7
Reply to Tulgar and Ercan Serifsoy: "Transversalis fascia plane block provides effective postoperative analgesia for cesarean section: New indication for known block." J Clin Anesth 2018;48:13-14. ( 30153536 )
2019
8
Continuous Erector Spinae Block at lumbar level (L4) for prolonged postoperative analgesia after hip surgery. ( 30153539 )
2019
9
Ultrasound guided rhomboid intercostal block provides effective analgesia for excision of elastofibroma extending to the subscapular space: The first report of use in anesthesia practice. ( 30172021 )
2019
10
Ultrasound-guided posterior ramus of spinal nerve block for anesthesia and analgesia in lumbar spinal surgery. ( 30176503 )
2019
11
Effects of the OPRM1 A118G Polymorphism (rs1799971) on Opioid Analgesia in Cancer Pain: A Systematic Review and Meta-Analysis. ( 30028366 )
2019
12
Subcutaneous or intravenous opioid administration by patient-controlled analgesia in cancer pain: a systematic literature review. ( 30056529 )
2019
13
Shared decision-making for postoperative analgesia: A semistructured qualitative study. ( 30063536 )
2019
14
Thoracic Epidural Analgesia and Mortality in Acute Pancreatitis: A Multicenter Propensity Analysis. ( 29194144 )
2018
15
Comparison of effectiveness of epidural analgesia and monitored anesthesia care for high-intensity focused ultrasound treatment of adenomyosis. ( 30303419 )
2018
16
Effects of thoracic epidural analgesia on exercise-induced myocardial ischaemia in refractory angina pectoris. ( 30374950 )
2018
17
Influence of preoperative information support on anxiety, pain and satisfaction with postoperative analgesia in children and adolescents after thoracic surgery: a randomized double blind study. ( 30305761 )
2018
18
Epidural Analgesia in Open Thoraco-abdominal Aortic Aneurysm Repair. ( 30385186 )
2018
19
Intraoperative insertion of paravertebral catheter for postoperative analgesia in retroperitoneal aortic aneurysm repair. ( 29579473 )
2018
20
Foley catheters are not routinely necessary in children treated with patient-controlled analgesia following perforated appendicitis. ( 29983187 )
2018
21
Effect of patient and nurse ethnicity on emergency department analgesia for children with appendicitis in israeli government hospitals. ( 29883525 )
2018
22
Two-Level Continuous Thoracic Paravertebral Nerve Blocks Providing Opioid-Free Postoperative Analgesia After Latissimus Dorsi Flap Breast Reconstruction: A Case Report. ( 29634527 )
2018
23
Continuous erector spinae plane block provides effective perioperative analgesia for breast reconstruction using tissue expanders: A report of two cases. ( 29065334 )
2018
24
Oral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain. ( 30147355 )
2018
25
Pain Management for Nonsyndromic Craniosynostosis: Adequate Analgesia in a Pediatric Cohort? ( 29489571 )
2018
26
Ultrasound-Guided Popliteal Sciatic Block Provides Adequate Analgesia During Urgent Endovascular Treatment of Critical Limb Ischemia with Resting Pain. ( 29038874 )
2018
27
Suppressing PKC-dependent membrane P2X3 receptor upregulation in dorsal root ganglia mediated electroacupuncture analgesia in rat painful diabetic neuropathy. ( 30084084 )
2018
28
Association between sedation-analgesia and neurodevelopment outcomes in neonatal hypoxic-ischemic encephalopathy. ( 29795315 )
2018
29
Lumbar epidural analgesia for labor in a parturient with a history of surgery for lumbar intradural ependymoma: Literature review and case presentation. ( 30488009 )
2018
30
Role of ASIC3, Nav1.7 and Nav1.8 in electroacupuncture-induced analgesia in a mouse model of fibromyalgia pain. ( 29343477 )
2018
31
Comparison of the Effects of Epidural Analgesia and Patient-controlled Intravenous Analgesia on Postoperative Pain Relief and Recovery After Laparoscopic Gastrectomy for Gastric Cancer. ( 30516718 )
2018
32
Effect of patient-controlled epidural analgesia versus patient-controlled intravenous analgesia on postoperative pain management and short-term outcomes after gastric cancer resection: a retrospective analysis of 3,042 consecutive patients between 2010 and 2015. ( 30233231 )
2018
33
High volume single injection lumbar erector spinae plane block provides effective analgesia for lower extremity herpes zoster. ( 30502675 )
2018
34
Erector spinae block for postoperative analgesia following axillary hidradenitis suppurativa resection: a case report. ( 30532584 )
2018
35
Horner's Syndrome and Upper Extremity Weakness After Quadratus Lumborum Block for Postcesarean Section Analgesia: A Case Report. ( 30543537 )
2018
36
Caudal Analgesia for Hypospadias in Pediatrics: Comparative Evaluation of Adjuvants Dexamethasone and Dexmedetomidine Combination versus Dexamethasone or Dexmedetomidine to Bupivacaine: A Prospective, Double-Blinded, Randomized Comparative Study. ( 30283169 )
2018
37
Low-Dose Versus High-Dose Postoperative Naloxone Infusion Combined With Patient-Controlled Analgesia for Adolescent Idiopathic Scoliosis Surgery: A Randomized Controlled Trial. ( 29886915 )
2018
38
A comparative study to evaluate ultrasound-guided transversus abdominis plane block versus ilioinguinal iliohypogastric nerve block for post-operative analgesia in adult patients undergoing inguinal hernia repair. ( 29720755 )
2018
39
Combined Selective Nerve Blockade and Local Infiltration Analgesia in a Total Shoulder Arthroplasty Patient With Chronic Pain and Severe Restrictive Lung Disease: A Case Report: Erratum. ( 29757797 )
2018
40
Obstetric anesthesia/analgesia does not affect disease course in multiple sclerosis: 10-year retrospective cohort study. ( 30047260 )
2018
41
Neutrophil-Mediated Endogenous Analgesia Contributes to Sex Differences in Oral Cancer Pain. ( 30405367 )
2018
42
Comparison of palonosetron and dexamethasone with ondansetron and dexamethasone for postoperative nausea and vomiting in postchemotherapy ovarian cancer surgeries requiring opioid-based patient-controlled analgesia: A randomised, double-blind, active controlled study. ( 30443060 )
2018
43
Looking Beyond the Pain: Can Effective Labor Analgesia Prevent the Development of Postpartum Depression? ( 29672384 )
2018
44
Labor Analgesia as a Predictor for Reduced Postpartum Depression Scores: A Retrospective Observational Study. ( 29239949 )
2018
45
Anesthesiologist preference for postoperative analgesia in major surgery patients with obstructive sleep apnea. ( 30100852 )
2018
46
Multimodal analgesia in crotalid snakebite envenomation: A novel use of femoral nerve block. ( 30224272 )
2018
47
Interspinous process decompression is associated with a reduction in opioid analgesia in patients with lumbar spinal stenosis. ( 30538533 )
2018
48
Visually induced analgesia during face or limb stimulation in healthy and migraine subjects. ( 30254484 )
2018
49
Molecular and functional PET-fMRI measures of placebo analgesia in episodic migraine: Preliminary findings. ( 29255671 )
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50
Effect of obesity on labor duration among nulliparous women with epidural analgesia. ( 30394154 )
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Sources

Variations for Pain Agnosia

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Expression for Pain Agnosia

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Search GEO for disease gene expression data for Pain Agnosia.
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Pathways for Pain Agnosia

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Pathways related to Pain Agnosia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Signaling by GPCR 66
Show member pathways
 13.46 AP2M1 CCK CNR1 HTR7 NPFF OPRL1
2
Peptide ligand-binding receptors 66
Show member pathways
 12.67 CCK CNR1 HTR7 NPFF OPRL1 OPRM1
3
Neuroscience 4
12.16 CNR1 OPRM1 POMC PSENEN
4
Syndecan-3-mediated signaling events 1
10.49 POMC PSENEN
5
Cell-type Dependent Selectivity of CCK2R Signaling 1
10.27 CCK CNR1
Sources

GO Terms for Pain Agnosia

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Cellular components related to Pain Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 perikaryon GO:0043204 9.5 CCK NPFF OPRM1
2 neuronal cell body GO:0043025 9.35 CCK PDYN PNOC TAC1 TRPV1
3 axon terminus GO:0043679 9.33 NPFF PDYN PNOC
4 clathrin adaptor complex GO:0030131 9.26 AP1M2 AP2M1
5 dendrite GO:0030425 9.17 CCK HTR7 NPFF OPRM1 PDYN PNOC

Biological processes related to Pain Agnosia according to GeneCards Suite gene sharing:

(show all 30)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.93 CCK NPFF OXT PDYN PNOC POMC
2 G protein-coupled receptor signaling pathway GO:0007186 9.9 CCK CNR1 HTR7 NPFF OPRL1 OPRM1
3 chemical synaptic transmission GO:0007268 9.89 HTR7 NPFF PDYN PNOC TAC1
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.84 NPFF OXT TAC1 TRPV1
5 memory GO:0007613 9.78 CCK CNR1 OXT
6 excitatory postsynaptic potential GO:0060079 9.76 NPFF OPRM1 TRPV1
7 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.74 CNR1 HTR7 OPRM1
8 response to cocaine GO:0042220 9.7 CNR1 OPRM1 OXT
9 negative regulation of blood pressure GO:0045776 9.69 CNR1 OPRL1 OXT
10 response to morphine GO:0043278 9.67 CNR1 NPFF OPRM1 TAC1
11 maternal process involved in female pregnancy GO:0060135 9.65 CNR1 NPFF
12 sensory perception of pain GO:0019233 9.65 CNR1 OPRL1 OPRM1 TAC1 TRPV1
13 response to food GO:0032094 9.64 OPRM1 OXT
14 response to pain GO:0048265 9.64 TAC1 TRPV1
15 estrous cycle GO:0044849 9.63 OPRL1 OPRM1
16 positive regulation of ossification GO:0045778 9.63 OXT TAC1
17 positive regulation of renal sodium excretion GO:0035815 9.62 OXT TAC1
18 eating behavior GO:0042755 9.62 CCK OPRL1 OPRM1 OXT
19 negative regulation of heart rate GO:0010459 9.61 NPFF TAC1
20 positive regulation of blood pressure GO:0045777 9.61 CNR1 NPFF OXT
21 negative regulation of appetite GO:0032099 9.6 CCK NPFF
22 opioid receptor signaling pathway GO:0038003 9.59 OPRL1 OPRM1
23 acute inflammatory response to antigenic stimulus GO:0002438 9.58 NPFF OPRM1
24 sensory perception GO:0007600 9.58 OPRL1 OPRM1 PNOC
25 positive regulation of sensory perception of pain GO:1904058 9.56 CCK OPRL1
26 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106072 9.55 OPRL1 OPRM1
27 positive regulation of gastric acid secretion GO:0060454 9.48 OPRL1 TRPV1
28 regulation of sensory perception of pain GO:0051930 9.35 CCK NPFF OPRL1 OPRM1 OXT
29 neuropeptide signaling pathway GO:0007218 9.17 NPFF OPRL1 OPRM1 PDYN PNOC POMC
30 signal transduction GO:0007165 10.22 CCK CNR1 HTR7 OPRL1 OPRM1 OXT

Molecular functions related to Pain Agnosia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.43 CCK OXT POMC
2 neuropeptide binding GO:0042923 9.32 OPRL1 OPRM1
3 opioid receptor activity GO:0004985 9.16 OPRL1 OPRM1
4 opioid peptide activity GO:0001515 8.96 PDYN PNOC
5 neuropeptide hormone activity GO:0005184 8.92 CCK NPFF OXT PNOC
Sources

Sources for Pain Agnosia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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