MCID: PNC034
MIFTS: 49

Pancreas Disease

Categories: Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreas Disease

Summaries for Pancreas Disease

Disease Ontology : 12 An endocrine system disease that is located in the pancreas.

MalaCards based summary : Pancreas Disease, also known as abnormality of the pancreas, is related to non-alcoholic fatty liver disease and pancreatic cancer, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Pancreas Disease is MIR21 (MicroRNA 21), and among its related pathways/superpathways are MicroRNAs in cancer and Cell Differentiation - Index. The drugs Propofol and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include pancreas, liver and spleen.

Wikipedia : 73 The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is... more...

Related Diseases for Pancreas Disease

Diseases related to Pancreas Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 294)
# Related Disease Score Top Affiliating Genes
1 non-alcoholic fatty liver disease 31.2 MIR34A MIR31 MIR30A MIR21 MIR199A1 MIR17
2 pancreatic cancer 30.8 SERPINA3 MIR483 MIR34A MIR31 MIR30A MIR221
3 disease by infectious agent 30.4 SERPINA3 MIR9-1 MIR34A MIR30A MIR221 MIR21
4 alcohol use disorder 30.2 MIR199A1 H2AC18 CCR6
5 endocrine pancreas disease 11.1
6 pancreas, annular 10.9
7 pancreatic agenesis 10.9
8 bacterial infectious disease 10.6 SERPINA3 MIR155 H2AC18 CCR6
9 coronavirus infectious disease 10.6 SERPINA3 MIR17 H2AC18 CCR6
10 intestinal benign neoplasm 10.6 SERPINA3 MIR21 MIR199A1 MIR196A1 MIR17 MIR145
11 mature t-cell and nk-cell lymphoma 10.6 MIR199A1 MIR17 MIR126 H2AC18 CCR6
12 pleural disease 10.6 MIR199A1 MIR17 MIR125A H2AC18 CCR6
13 parasitic helminthiasis infectious disease 10.6 SERPINA3 MIR21 H2AC18 CCR6
14 extrinsic cardiomyopathy 10.6 SERPINA3 MIR21 MIR199A1 MIR142 H2AC18 CCR6
15 esophagus adenocarcinoma 10.6 MIR21 MIR199A1 MIR196A1 MIR145
16 pre-malignant neoplasm 10.6 SERPINA3 MIR17 MIR142 H2AC18 CCR6
17 b-cell lymphoma 10.6 MIR34A MIR21 MIR17 MIR155 MIR142
18 retinal vascular disease 10.6 MIR30A MIR21 MIR199A1 MIR17 MIR126 H2AC18
19 blood protein disease 10.6 MIR17 MIR126 H2AC18 CCR6
20 autoimmune disease of gastrointestinal tract 10.6 SERPINA3 MIR199A1 MIR196A1 MIR142 H2AC18 CCR6
21 bone resorption disease 10.6 SERPINA3 MIR199A1 MIR196A1 MIR142 H2AC18 CCR6
22 thyroid gland disease 10.6 SERPINA3 MIR9-1 MIR221 MIR199A1 MIR17 MIR142
23 microcystic adenoma 10.6 SERPINA3 MIR21 MIR126
24 heart valve disease 10.6 SERPINA3 MIR486-1 MIR21 MIR199A1 MIR17 MIR126
25 x-linked recessive disease 10.6 SERPINA3 MIR196A1 MIR142 H2AC18 CCR6
26 bone remodeling disease 10.6 SERPINA3 MIR199A1 MIR142 H2AC18 CCR6
27 testicular disease 10.6 SERPINA3 MIR199A1 H2AC18 CCR6
28 gastrointestinal system benign neoplasm 10.6 SERPINA3 MIR483 MIR30A MIR21 MIR199A1 MIR196A1
29 miyoshi muscular dystrophy 1 10.6 MIR34A MIR30A MIR221 MIR21 MIR155
30 ovary adenocarcinoma 10.6 SERPINA3 MIR30A MIR17 H2AC18
31 in situ carcinoma 10.6 SERPINA3 MIR17 MIR142 MIR126 H2AC18
32 hypersensitivity reaction type iv disease 10.6 SERPINA3 MIR155 H2AC18 CCR6
33 autoimmune disease of endocrine system 10.6 MIR142 MIR125A H2AC18 CCR6
34 cerebral arterial disease 10.6 SERPINA3 MIR199A1 MIR145 MIR125A
35 inclusion body myositis 10.6 SERPINA3 MIR34A MIR221 MIR21 MIR155
36 primary bacterial infectious disease 10.6 SERPINA3 MIR21 MIR155 MIR142 MIR125A H2AC18
37 muscle cancer 10.6 SERPINA3 MIR9-1 MIR199A1 MIR196A1 MIR142 H2AC18
38 lysosomal storage disease 10.6 SERPINA3 MIR21 MIR199A1 H2AC18 CCR6
39 aortic disease 10.6 SERPINA3 MIR21 MIR199A1 MIR17 MIR145 MIR126
40 bone sarcoma 10.6 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17 MIR142
41 ovarian serous carcinoma 10.6 MIR21 MIR199A1 MIR145 MIR125A MIR10B
42 muscular disease 10.6 SERPINA3 MIR9-1 MIR221 MIR21 MIR199A1 MIR196A1
43 progressive relapsing multiple sclerosis 10.6 SERPINA3 H2AC18 CCR6
44 lipid storage disease 10.6 SERPINA3 MIR21 MIR199A1 MIR155 MIR142 H2AC18
45 infratentorial cancer 10.6 MIR9-1 MIR199A1 MIR196A1 MIR17 MIR142 H2AC18
46 substance abuse 10.6 SERPINA3 MIR199A1 H2AC18 CCR6
47 uveal disease 10.6 SERPINA3 MIR9-1 MIR199A1 MIR142 MIR125A H2AC18
48 oropharynx cancer 10.6 SERPINA3 MIR9-1 MIR199A1 H2AC18
49 dermatomyositis 10.6 MIR34A MIR30A MIR221 MIR21 MIR155
50 aortic valve disease 2 10.6 SERPINA3 MIR486-1 MIR34A MIR21 MIR199A1 MIR17

Graphical network of the top 20 diseases related to Pancreas Disease:



Diseases related to Pancreas Disease

Symptoms & Phenotypes for Pancreas Disease

UMLS symptoms related to Pancreas Disease:


nausea and vomiting; constipation; abdominal pain; diarrhea; dyspepsia; icterus; heartburn; gastrointestinal gas; digestive system symptom

Drugs & Therapeutics for Pancreas Disease

Drugs for Pancreas Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 90)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
3
Acetaminophen Approved Phase 4 103-90-2 1983
4
Alfentanil Approved, Illicit Phase 4 71195-58-9 51263
5
Remifentanil Approved Phase 4 132875-61-7 60815
6 Analgesics Phase 4
7 Analgesics, Non-Narcotic Phase 4
8 Narcotics Phase 4
9 Analgesics, Opioid Phase 4
10 Hypnotics and Sedatives Phase 4
11 Anesthetics, General Phase 4
12 Anesthetics, Intravenous Phase 4
13 Antipyretics Phase 4
14
Secretin Approved Phase 3 108153-74-8
15
Scopolamine Approved, Investigational Phase 3 51-34-3, 6533-68-2 5184
16
Sufentanil Approved, Investigational Phase 2, Phase 3 56030-54-7 41693
17
Sevoflurane Approved, Vet_approved Phase 2, Phase 3 28523-86-6 5206
18
Ropivacaine Approved Phase 2, Phase 3 84057-95-4 71273 175805
19
Bupivacaine Approved, Investigational Phase 2, Phase 3 2180-92-9, 38396-39-3 2474
20
Cefoxitin Approved Phase 3 35607-66-0 441199
21
Cefotaxime Approved Phase 3 63527-52-6 456256 5742673
22
Tazobactam Approved Phase 3 89786-04-9 123630
23
Piperacillin Approved Phase 3 66258-76-2 43672
24
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
25
Gemcitabine Approved Phase 3 95058-81-4 60750
26
Somatostatin Approved, Investigational Phase 2, Phase 3 38916-34-6, 51110-01-1 53481605
27 Liver Extracts Phase 3
28 Gastrointestinal Agents Phase 3
29 Vasodilator Agents Phase 3
30 Parasympatholytics Phase 3
31 Antiemetics Phase 3
32 Cholinergic Agents Phase 3
33 Mydriatics Phase 3
34 Drotaverin Phase 3
35 Muscarinic Antagonists Phase 3
36 Bromides Phase 3
37 Butylscopolammonium Bromide Phase 3
38 Cholinergic Antagonists Phase 3
39 Pharmaceutical Solutions Phase 2, Phase 3
40 Anesthetics Phase 3
41 Anesthetics, Local Phase 2, Phase 3
42 Piperacillin, Tazobactam Drug Combination Phase 3
43 beta-Lactamase Inhibitors Phase 3
44 Tubulin Modulators Phase 3
45 Antimitotic Agents Phase 3
46 Albumin-Bound Paclitaxel Phase 3
47 Immunologic Factors Phase 3
48 Immunosuppressive Agents Phase 3
49 Antiviral Agents Phase 3
50 Antimetabolites Phase 3

Interventional clinical trials:

(show top 50) (show all 98)
# Name Status NCT ID Phase Drugs
1 Prevention for Surgical Site Infection After Pancreatic Resection Unknown status NCT00661648 Phase 4
2 Role of Scheduled Intravenous Acetaminophen for Postoperative Pain Management in an Enhanced Recovery After Surgery (ERAS) Population: A Prospective, Randomized, Double-Blind and Placebo-Controlled Clinical Trial Completed NCT03198871 Phase 4 Acetaminophen Injectable Product;Sodium Chloride 0.9%, Intravenous
3 Alfentanil vs Remifentanil in Patient-controlled Sedation During ERCP.A Randomized Double-blind Study Completed NCT01350037 Phase 4 alfentanil;remifentanil
4 A Prospective Multi-center Randomized Study of the Difference in Diagnostic Yield Between EUSFNA Needles With and Without a Side Port in Pancreatic Masses Completed NCT02092519 Phase 4
5 Randomized Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
6 A Placebo Controlled, Double-Blind, Parallel, Multicenter Study of Synthetic Human Secretin (ChiRhoStim®) Administered Intravenously to Stimulate Exocrine Pancreas Fluid Secretion for Collection Via Endoscope and Laboratory Analysis of DNA Markers Completed NCT01087801 Phase 3 ChiRhoStim;Placebo
7 Phase III Study of Efficacy of Remote Ischemic Preconditioning in Improving Outcomes in Organ Transplantation Completed NCT00975702 Phase 3
8 Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During ERCP: a Prospective, Multicenter Randomized Controlled Trial Completed NCT00731198 Phase 3 Drotaverine hydrochloride;Hyoscine-N-butylbromide
9 The Impact of an Epidural Anesthetic on the Consumption of Sevoflurane in Major Abdominal Surgery Recruiting NCT04021264 Phase 2, Phase 3 Ropivacaine-Sufentanil;Dextrose 5
10 A Phase III Multicenter, Open Label Randomized Controlled Trial of Cefoxitin Versus Piperacillin-Tazobactam as Surgical Antibiotic Prophylaxis in Patients Undergoing Pancreatoduodenectomy Recruiting NCT03269994 Phase 3 Cefoxitin;Piperacillin-tazobactam
11 A Phase 3, Multicenter, Open-label, Randomized Study of Nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Subjects With Surgically Resected Pancreatic Adenocarcinoma Active, not recruiting NCT01964430 Phase 3 nab-Paclitaxel;Gemcitabine
12 Randomized Control Trial Comparing Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics Enrolling by invitation NCT04329039 Phase 2, Phase 3 Somatostatin analog
13 A Trial Evaluating Escalating Doses and the Safety of Intracystic Injection of NanoPac® in Subjects With Mucinous Cystic Pancreatic Neoplasms Completed NCT03188991 Phase 2 NanoPac®
14 A Global, Multi-center, Open-label, Phase 2 Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer Completed NCT00902291 Phase 2
15 A Single-arm Phase II Trial of Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy Completed NCT03410914 Phase 2
16 An Open-Label Phase 2 Study of AGS-1C4D4 in Pancreatic Cancer Subjects Previously Treated in Protocol 2008002 Completed NCT01608711 Phase 2
17 Phase IIa Trial Evaluating the Safety of Intratumoral Injection of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma Recruiting NCT03077685 Phase 2 NanoPac®
18 A Phase I/II Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan (GAX-CI) in Combination in Metastatic Pancreatic Cancer Recruiting NCT03535727 Phase 1, Phase 2 Nab-paclitaxel;Gemcitabine;Capecitabine;Cisplatin;Irinotecan;Nab-paclitaxel;Gemcitabine;Capecitabine;Cisplatin;Irinotecan
19 Evaluation of the Effect of Ocoxin-Viusid® Nutritional Supplement in the Life Quality in Patients Diagnosed With Advanced Pancreatic Adenocarcinoma. Phase II Recruiting NCT03717298 Phase 2
20 Safety and Efficacy Study of IL-10 (Tenovil TM) in the Prevention of Post-ERCP Acute Pancreatitis (Study P02580)(TERMINATED) Terminated NCT00040131 Phase 2 IL-10
21 89Zr-MMOT0530A PET Imaging in Patients With Unresectable Pancreatic or Platinum-resistant Ovarian Cancer Before Treatment With DMOT4039A. A Separate Study to the Phase I Study Protocol DMO4993g Completed NCT01832116 Phase 1 89Zr-MMOT0530A
22 Zhujiang Hospital of the Southern Medical University Unknown status NCT03074708
23 Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases Trial " EASYSPY " Unknown status NCT03190343
24 Effectiveness of Metal Protheses Covered in "Diabolo" in Treatment of Necrosis of Origin Pancreatic: Trial "DIABOLOPIG" Unknown status NCT02739074
25 Cell-free DNA Promoter Hypermethylation in Plasma From Patients With Pancreatic Adenocarcinoma, Compared to Patients With Pancreatitis and Pancreatitis and Patients Screened for, But Not Having Pancreatic Adenocarcinoma." Unknown status NCT02079363
26 The Effect of Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide on the Complications After Pancreatectomy. A Prospective, Multicenter Clinical Trial Unknown status NCT03398941 Preoperative Long Period Octreotide Combined With Postoperative Short Period Octreotide
27 The Effect of Doctor-nurse-patient Cooperative Analgesic Linkage Program on Movement Evoked Pain After Laparotomy for Patients With Hepatobiliary and Pancreatic Disease Unknown status NCT03823846 Routine Dezocine injection;Adjusted Dezocine injection;Routine Dynastat or Flurbiprofen Axetil jinjection;Adjusted Dynastat or Flurbiprofen Axetil jinjection;normal analgesia pump administration;adjusted analgesia pump administration
28 Benefit of Tight Glycemic Control in Surgical Patients: Prospective Randomized Clinical Trial Unknown status NCT00735228
29 A Prospective, Multicentric, Randomized Trial Comparing Early Enteral Nutrition Versus Parenteral Nutrition After Pancreaticoduodenectomy Unknown status NCT01580527
30 Enhanced Recovery After Surgery for Hepatobiliary-Pancreatic Surgery Unknown status NCT03772392
31 Endoscopic Retrograde Cholangiopancreatography, Endoscopic Ultrasound and Interventional Endoscopy in Pancreatico-biliary, Gastrointestinal and Esophageal Disorders Unknown status NCT01438385
32 Comparison Between Continuous Infusion and Intermittent Bolus Injection of Propofol for Deep Sedation During Endoscopic Retrograde Cholangiopancreatography: a Prospective Randomized Controlled Study Unknown status NCT01900938 Midazolam;Propofol
33 A Prospective Study to Evaluate the Outcome of Liver, Pancreas and Thyroid Function in Severely Burned Patients Unknown status NCT03598283
34 Remote Ischemic Conditioning (RIC) to Decrease Post-Operative Complications After Major Abdominal Surgery - A Phase IIa Trial Unknown status NCT03234543
35 Indications and Outcomes of Gastrointestinal Endoscopic Ultrasound in Tanta-Egypt: Initial Experience. Unknown status NCT03267355
36 Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis Unknown status NCT01427712
37 Evaluation of Combined Endoscopic Ultrasound Ductal Evaluation Before & After Secretin Stimulation in One EUS Session for the Diagnosis of Exocrine Pancreas Disease Completed NCT01997476
38 The Impact of Non-Alcoholic Fatty Pancreas Disease on Outcome of Acute Pancreatitis Completed NCT03394378
39 A Network on the Quality of ERCP, on the Organization of the Endoscopic Units and on the Training of the Endoscopists in Italy Completed NCT02971579
40 Safety and Efficacy of the New 20 mm Lumen Apposing Metal Stent (Lams) for Endoscopic Treatment of Pancreatic and Peripancreatic Fluid Collections: a Large, International, Multicenter Study Completed NCT03578770
41 A Prospective, Single Arm Study to Evaluate the Feasibility of the Archimedes Biodegradable Biliary and Pancreatic Stents Placement Completed NCT03767166
42 Use of Serum Proteome on the Early Diagnosis of Malignant Biliary-Pancreatic Disease Completed NCT00559598
43 Magnetic Resonance Cholangio-pancreatography (MRCP) for Suspected Bilio-pancreatic Disease: Should the Endoscopist Take a Second Look? Completed NCT01538368
44 Early (4 Days) Versus Standard Drainage Removal of the Abdominal Cavity After Pancreaticoduodenectomy- - A Randomized Multicenter Study Completed NCT01368094
45 A Pilot Study Evaluating Health-related Quality of Life Endpoints in Patients Undergoing Minimally Invasive Versus Open Pancreaticoduodenectomy Completed NCT02638818
46 Influence of the Endoscopist Case Volumen on Endoscopic Retrograde CholangioPanceratography Outcomes Completed NCT04705740
47 Comparison of Confocal Laser Endomicroscopic IN Vivo Diagnosis and EX Vivo Examination (INDEX Study) Against Surgical Histopathology of Cystic Pancreatic Lesions Completed NCT02516488
48 Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography in Intensive Care Patients Undergoing Epigastric Surgery Completed NCT02337673
49 Single-operator Wire-guided ERCP Cannulation Technique: a Single-center Randomized Controlled Study Completed NCT01598142
50 Biospecimens for the Early Detection, Prevention, Diagnosis and Treatment of Diseases of the Pancreas. Completed NCT01392027

Search NIH Clinical Center for Pancreas Disease

Genetic Tests for Pancreas Disease

Anatomical Context for Pancreas Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Pancreas Disease:

19
Pancreas

MalaCards organs/tissues related to Pancreas Disease:

40
Pancreas, Liver, Spleen, Thyroid, Kidney, Heart, Skeletal Muscle

Publications for Pancreas Disease

Articles related to Pancreas Disease:

(show top 50) (show all 2647)
# Title Authors PMID Year
1
Pancreatic Cancer-Associated Diabetes is Clinically Distinguishable From Conventional Diabetes. 61
33453685 2021
2
Deoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development. 61
33811703 2021
3
Pancreas segmentation using a dual-input v-mesh network. 61
33550009 2021
4
Analysis of T-cell receptor repertoire in peripheral blood of patients with pancreatic cancer and other pancreatic diseases. 61
33682267 2021
5
Endoscopic management of pancreatic diseases in patients with surgically altered anatomy: clinical outcomes of combination of double-balloon endoscopy- and endoscopic ultrasound-guided interventions. 61
32434287 2021
6
Circulating Protein Biomarkers for Use in Pancreatic Ductal Adenocarcinoma Identification. 61
33737308 2021
7
Recent advances in prevention and management of endoscopic retrograde cholangiopancreatography-related duodenal perforation. 61
33786113 2021
8
Single-Nucleus and In Situ RNA-Sequencing Reveal Cell Topographies in the Human Pancreas. 61
33212097 2021
9
Pancreatitis, panniculitis, and polyarthritis syndrome complicated with terminal pancreatic adenocarcinoma managed with intra-articular knee aspiration, intra-articular lidocaine and corticosteroid injection, and decompression of panniculitis: A case report. 61
33717781 2021
10
[Pancreatic diseases]. 61
33592656 2021
11
The impact of the multidisciplinary tumor board (MDTB) on the management of pancreatic diseases in a tertiary referral center. 61
33399076 2021
12
GRUPUGE Perspective: Endoscopic Ultrasound-Guided Fine-Needle Tattooing and Fiducial Placement in Pancreatic Cancer. 61
33791397 2021
13
Evaluation of serum ATX and LPA as potential diagnostic biomarkers in patients with pancreatic cancer. 61
33568105 2021
14
Fatal case of pancreatic panniculitis caused by occult neuroendocrine tumor in the corresponding organ: A case report and review of the published work. 61
33073392 2021
15
Pancreatic Disorders in Patients with Inflammatory Bowel Disease. 61
33625614 2021
16
Pancreatic panniculitis in a patient with pancreatic adenosquamous carcinoma. 61
33124679 2021
17
Two-stage deep learning model for fully automated pancreas segmentation on computed tomography: Comparison with intra-reader and inter-reader reliability at full and reduced radiation dose on an external dataset. 61
33595105 2021
18
Identification and validation of a multivariable prediction model based on blood plasma and serum metabolomics for the distinction of chronic pancreatitis subjects from non-pancreas disease control subjects. 61
33541865 2021
19
Genetically modified attenuated salmonid alphavirus: A potential strategy for immunization of Atlantic salmon. 61
33591590 2021
20
LncRNA MEG3 Participates in Caerulein-Induced Inflammatory Injury in Human Pancreatic Cells via Regulating miR-195-5p/FGFR2 Axis and Inactivating NF-κB Pathway. 61
32856219 2021
21
Targeting Macrophage Migration Inhibitory Factor in Acute Pancreatitis and Pancreatic Cancer. 61
33776775 2021
22
Application of artificial intelligence in pancreaticobiliary diseases. 61
33644756 2021
23
Nonalcoholic Fatty Pancreas Disease: Role in Metabolic Syndrome, "Prediabetes," Diabetes and Atherosclerosis. 61
33469809 2021
24
Clinical, surgical, pathological and follow-up features of kidney cancer patients with Von Hippel-Lindau syndrome: novel insights from a large consortium. 61
33416974 2021
25
Artificial intelligence for the management of pancreatic diseases. 61
33065754 2021
26
Timing of endoscopic therapy for acute bilio-pancreatic diseases: a practical overview. 61
33654349 2021
27
Experimental Modeling of Eosinophil-Associated Diseases. 61
33486743 2021
28
Sigmoid colon perforation caused by migrated plastic biliary stents: a case report. 61
32865713 2021
29
Indirectly radioiodinated exendin-4 as an analytical tool for in vivo detection of glucagon-like peptide-1 receptor in a disease setting. 61
33067731 2021
30
Reg3β: A Potential Therapeutic Target for Tissue Injury and Inflammation-Associated Disorders. 61
33426979 2021
31
Delayed Processing of Secretin-Induced Pancreas Fluid Influences the Quality and Integrity of Proteins and Nucleic Acids. 61
33370019 2021
32
EUS and ERCP: A rationale categorization of a productive partnership. 61
33353903 2021
33
Current status of artificial intelligence analysis for endoscopic ultrasonography. 61
33098123 2021
34
[The role of endoscopic ultrasound in diagnosis and staging of pancreatic ductal adenocarcinoma.] 61
33512361 2021
35
Safety and effectiveness of linagliptin in Korean patients with type 2 diabetes: A postmarketing surveillance study. 61
33464714 2021
36
Sleep disorders related to nutrition and digestive diseases: a neglected clinical condition. 61
33437194 2021
37
Simulated twin-phase pancreatic CT generated using single portal venous phase dual-energy CT acquisition in pancreatic ductal adenocarcinoma. 61
33454806 2021
38
Probe-based confocal laser endomicroscopy for the diagnosis of pancreatic ductal structures. 61
32433791 2021
39
[Postpancreatectomy hemorrhage]. 61
33395516 2021
40
Effect of a novel DNA vaccine against pancreas disease caused by salmonid alphavirus subtype 3 in Atlantic salmon (Salmo salar). 61
33285168 2021
41
Development and evaluation of a method for concentration and detection of salmonid alphavirus from seawater. 61
33035567 2021
42
Fatty Pancreas: Disease or Finding? 61
33624707 2021
43
New advances in CT imaging of pancreas diseases: a narrative review. 61
33447580 2020
44
[A several-week history of inflammatory changes in the right foot and right hand of a 57-year-old male patient]. 61
33337524 2020
45
Outcome of interventional radiology for delayed postoperative hemorrhage in hepatobiliary and pancreatic surgery. 61
32525234 2020
46
Gut microbiome alterations in type 1 autoimmune pancreatitis after induction of remission by prednisolone. 61
32880930 2020
47
Endoscopic Ultrasound. 61
33128884 2020
48
Nanopore whole genome sequencing and partitioned phylogenetic analysis supports a new salmonid alphavirus genotype (SAV7). 61
33331288 2020
49
Paediatric pancreatic diseases. 61
33197977 2020
50
Abstinent patients with alcohol use disorders show an altered plasma cytokine profile: Identification of both interleukin 6 and interleukin 17A as potential biomarkers of consumption and comorbid liver and pancreatic diseases. 61
32536325 2020

Variations for Pancreas Disease

ClinVar genetic disease variations for Pancreas Disease:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 CFTR NM_000492.4(CFTR):c.224G>A (p.Arg75Gln) SNV not provided 35839 rs1800076 GRCh37: 7:117149147-117149147
GRCh38: 7:117509093-117509093

Expression for Pancreas Disease

Search GEO for disease gene expression data for Pancreas Disease.

Pathways for Pancreas Disease

Pathways related to Pancreas Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.96 MIR9-1 MIR483 MIR34A MIR31 MIR30A MIR221
2 10.71 MIR9-1 MIR221 MIR199A1
3 10.27 MIR199A1 MIR145

GO Terms for Pancreas Disease

Cellular components related to Pancreas Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.85 SERPINA3 MIR9-1 MIR34A MIR21 MIR17 MIR155
2 extracellular space GO:0005615 9.77 SERPINA3 MIR486-1 MIR31 MIR30A MIR221 MIR21
3 extracellular vesicle GO:1903561 9.17 MIR34A MIR30A MIR221 MIR21 MIR17 MIR126

Biological processes related to Pancreas Disease according to GeneCards Suite gene sharing:

(show all 38)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.99 MIR34A MIR21 MIR17 MIR155 MIR125A
2 positive regulation of protein kinase B signaling GO:0051897 9.92 MIR221 MIR21 MIR199A1 MIR126
3 positive regulation of angiogenesis GO:0045766 9.89 MIR31 MIR30A MIR21 MIR199A1 MIR126
4 negative regulation of cell migration GO:0030336 9.88 MIR9-1 MIR34A MIR21 MIR145 MIR126
5 cellular response to hypoxia GO:0071456 9.87 MIR34A MIR17 MIR155 MIR126
6 negative regulation of angiogenesis GO:0016525 9.86 MIR34A MIR21 MIR145 MIR125A
7 positive regulation of inflammatory response GO:0050729 9.83 MIR21 MIR155 MIR126
8 negative regulation of inflammatory response GO:0050728 9.8 MIR31 MIR221 MIR155 MIR145 MIR142 MIR126
9 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.79 MIR221 MIR21 MIR17
10 negative regulation of cytokine production involved in inflammatory response GO:1900016 9.78 MIR221 MIR155 MIR125A
11 negative regulation of cardiac muscle cell apoptotic process GO:0010667 9.77 MIR21 MIR199A1 MIR145
12 positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 9.76 MIR31 MIR126 MIR10B
13 negative regulation of sprouting angiogenesis GO:1903671 9.75 MIR34A MIR221 MIR17
14 positive regulation of blood vessel endothelial cell migration GO:0043536 9.73 MIR31 MIR30A MIR221 MIR126
15 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903589 9.71 MIR21 MIR126 MIR10B
16 negative regulation of vascular endothelial growth factor production GO:1904046 9.71 MIR34A MIR199A1 MIR17 MIR125A
17 negative regulation of low-density lipoprotein particle clearance GO:0010989 9.7 MIR199A1 MIR17 MIR155
18 positive regulation of connective tissue replacement GO:1905205 9.69 MIR34A MIR199A1 MIR155
19 positive regulation of cardiac muscle cell apoptotic process GO:0010666 9.68 MIR34A MIR17
20 negative regulation of cell adhesion molecule production GO:0060354 9.67 MIR221 MIR155
21 positive regulation of lipid storage GO:0010884 9.67 MIR34A MIR10B
22 negative regulation of hydrogen peroxide-induced cell death GO:1903206 9.67 MIR17 MIR155
23 positive regulation of sprouting angiogenesis GO:1903672 9.67 MIR31 MIR155 MIR126 MIR125A
24 negative regulation of cytokine-mediated signaling pathway GO:0001960 9.66 MIR21 MIR125A
25 positive regulation of microglial cell activation GO:1903980 9.65 MIR155 MIR142
26 negative regulation by host of viral genome replication GO:0044828 9.65 MIR221 MIR155
27 positive regulation of metalloendopeptidase activity GO:1904685 9.65 MIR21 MIR17
28 negative regulation of cell migration involved in sprouting angiogenesis GO:0090051 9.65 MIR483 MIR221 MIR199A1 MIR196A1 MIR155
29 negative regulation of vascular wound healing GO:0061044 9.64 MIR34A MIR155
30 negative regulation of bicellular tight junction assembly GO:1903347 9.64 MIR155 MIR142
31 negative regulation of regulatory T cell differentiation GO:0045590 9.63 MIR21 MIR155
32 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.63 MIR21 MIR17
33 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.63 MIR199A1 MIR17 MIR155
34 negative regulation of interleukin-21 production GO:0032705 9.61 MIR221 MIR21
35 miRNA mediated inhibition of translation GO:0035278 9.61 MIR9-1 MIR483 MIR31 MIR221 MIR21 MIR17
36 negative regulation of interleukin-16 production GO:0032699 9.55 MIR145 MIR125A
37 gene silencing by miRNA GO:0035195 9.55 MIR9-1 MIR486-1 MIR483 MIR34A MIR31 MIR30A
38 negative regulation of leukocyte adhesion to vascular endothelial cell GO:1904995 9.46 MIR31 MIR221 MIR155 MIR125A

Molecular functions related to Pancreas Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.7 MIR9-1 MIR34A MIR31 MIR30A MIR21 MIR17
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.53 MIR9-1 MIR483 MIR34A MIR31 MIR30A MIR221
3 RNA polymerase II complex binding GO:0000993 9.33 MIR145 MIR126 MIR125A

Sources for Pancreas Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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