MCID: PNC127
MIFTS: 24

Pancreatic Adenosquamous Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Adenosquamous Carcinoma

MalaCards integrated aliases for Pancreatic Adenosquamous Carcinoma:

Name: Pancreatic Adenosquamous Carcinoma 12 15
Adenosquamous Carcinoma of the Pancreas 12
Adenosquamous Carcinoma of Pancreas 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5637
NCIt 50 C5721
UMLS 73 C1335299

Summaries for Pancreatic Adenosquamous Carcinoma

Disease Ontology : 12 A pancreatic ductal carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Pancreatic Adenosquamous Carcinoma, also known as adenosquamous carcinoma of the pancreas, is related to adenosquamous carcinoma and pancreatic ductal adenocarcinoma. An important gene associated with Pancreatic Adenosquamous Carcinoma is UPF1 (UPF1, RNA Helicase And ATPase), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Hepatitis C. Affiliated tissues include pancreas, salivary gland and lung, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Pancreatic Adenosquamous Carcinoma

Diseases related to Pancreatic Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 30.7 KRAS PTHLH
2 pancreatic ductal adenocarcinoma 10.0
3 adenocarcinoma 10.0
4 splenic abscess 10.0
5 mucoepidermoid carcinoma 10.0
6 splenomegaly 10.0
7 lung squamous cell carcinoma 9.8 KRAS PTHLH

Graphical network of the top 20 diseases related to Pancreatic Adenosquamous Carcinoma:



Diseases related to Pancreatic Adenosquamous Carcinoma

Symptoms & Phenotypes for Pancreatic Adenosquamous Carcinoma

GenomeRNAi Phenotypes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.9 KRAS
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.9 IFNA17
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.9 KRAS
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.9 IFNA17
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.9 KRAS
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 9.9 IFNA17 KRAS
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.9 IFNA17
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.9 IFNA17
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.9 KRAS
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.9 KRAS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.9 KRAS
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.9 KRAS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.9 IFNA17
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.9 KRAS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.9 IFNA17
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.9 IFNA17 KRAS
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.9 IFNA17

Drugs & Therapeutics for Pancreatic Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Pancreatic Adenosquamous Carcinoma

Genetic Tests for Pancreatic Adenosquamous Carcinoma

Anatomical Context for Pancreatic Adenosquamous Carcinoma

MalaCards organs/tissues related to Pancreatic Adenosquamous Carcinoma:

41
Pancreas, Salivary Gland, Lung

Publications for Pancreatic Adenosquamous Carcinoma

Articles related to Pancreatic Adenosquamous Carcinoma:

(show all 25)
# Title Authors Year
1
A retroperitoneal mass confirmed as a pancreatic adenosquamous carcinoma by endoscopic ultrasound-guided fine-needle aspiration. ( 29069702 )
2018
2
Pancreatic adenosquamous carcinoma masquerading as a locally invading splenic abscess. ( 29740918 )
2018
3
"Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features. ( 30138216 )
2018
4
PD-L1 expression in pancreatic adenosquamous carcinoma: PD-L1 expression is limited to the squamous component. ( 30477643 )
2018
5
Genomic signatures of pancreatic adenosquamous carcinoma (PASC). ( 28722109 )
2017
6
Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a<i>CDKN2A</i>germline mutation carrier. ( 28979722 )
2017
7
A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet. ( 26863381 )
2016
8
Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report. ( 25674740 )
2015
9
The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. ( 24859531 )
2014
10
Clinical characteristics of adenosquamous carcinoma of the pancreas: a matched case-control study. ( 24518509 )
2014
11
Pancreatic adenosquamous carcinoma with 7-year survival: a case report and literature review. ( 23176255 )
2013
12
Splenomegaly as the first manifestation of pancreatic adenosquamous carcinoma: a case report. ( 23864460 )
2012
13
Successful treatment with GEMOX in patient with metastatic pancreatic adenosquamous carcinoma. ( 21617724 )
2011
14
Pancreatic adenosquamous carcinoma presenting as splenic rupture: report of a case. ( 21626340 )
2011
15
Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patients. ( 19801164 )
2010
16
Granulocyte-colony stimulating factor-producing pancreatic adenosquamous carcinoma showing aggressive clinical course. ( 19420814 )
2009
17
Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma. ( 18764955 )
2008
18
Complete response of a pancreatic adenosquamous carcinoma to chemoradiotherapy. ( 18307024 )
2008
19
Education of imaging. Hepatobiliary and pancreatic: adenosquamous carcinoma of the pancreas. ( 18410615 )
2008
20
Adenosquamous carcinoma of the pancreas. ( 10597404 )
1999
21
FNAC guided by computed tomography in the diagnosis of primary pancreatic adenosquamous carcinoma. A report of three cases. ( 9850660 )
1998
22
Adenosquamous carcinoma of the pancreas: report of two cases. ( 9672355 )
1998
23
Intraoperative cytodiagnosis of pancreatic adenosquamous carcinoma: a case report. ( 3522134 )
1986
24
&amp;quot;COLO 357,&amp;quot; a human pancreatic adenosquamous carcinoma: growth in artificial capillary culture and in nude mice. ( 6640542 )
1983
25
Adenosquamous carcinoma of the pancreas. ( 6879736 )
1983

Variations for Pancreatic Adenosquamous Carcinoma

Expression for Pancreatic Adenosquamous Carcinoma

Search GEO for disease gene expression data for Pancreatic Adenosquamous Carcinoma.

Pathways for Pancreatic Adenosquamous Carcinoma

Pathways related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.64 IFNA17 KRAS MAML2
2 11.27 IFNA17 KRAS
3 10.9 IFNA17 KRAS

GO Terms for Pancreatic Adenosquamous Carcinoma

Biological processes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 8.62 KRAS PTHLH

Sources for Pancreatic Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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