MCID: PNC127
MIFTS: 26

Pancreatic Adenosquamous Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Adenosquamous Carcinoma

MalaCards integrated aliases for Pancreatic Adenosquamous Carcinoma:

Name: Pancreatic Adenosquamous Carcinoma 12 15 17
Adenosquamous Carcinoma of the Pancreas 12
Adenosquamous Carcinoma of Pancreas 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5637
NCIt 51 C5721
UMLS 74 C1335299

Summaries for Pancreatic Adenosquamous Carcinoma

Disease Ontology : 12 A pancreatic ductal carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Pancreatic Adenosquamous Carcinoma, also known as adenosquamous carcinoma of the pancreas, is related to adenosquamous carcinoma and mucoepidermoid carcinoma. An important gene associated with Pancreatic Adenosquamous Carcinoma is UPF1 (UPF1 RNA Helicase And ATPase), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Jak-Stat Signaling Pathway (sino). Affiliated tissues include pancreas and salivary gland, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Pancreatic Adenosquamous Carcinoma

Diseases related to Pancreatic Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 30.3 KRAS PTHLH
2 mucoepidermoid carcinoma 10.1
3 pancreatic ductal adenocarcinoma 10.0
4 gastrointestinal stromal tumor 10.0
5 adenocarcinoma 10.0
6 splenic abscess 10.0
7 splenomegaly 10.0

Graphical network of the top 20 diseases related to Pancreatic Adenosquamous Carcinoma:



Diseases related to Pancreatic Adenosquamous Carcinoma

Symptoms & Phenotypes for Pancreatic Adenosquamous Carcinoma

GenomeRNAi Phenotypes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

27 (show all 16)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.88 KRAS
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.88 IFNA17
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.88 KRAS
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.88 IFNA17
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.88 KRAS
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 9.88 IFNA17 KRAS
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.88 IFNA17
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.88 IFNA17
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.88 KRAS
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.88 KRAS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.88 KRAS
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.88 KRAS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.88 IFNA17
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.88 KRAS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.88 IFNA17 KRAS
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.88 IFNA17

Drugs & Therapeutics for Pancreatic Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Pancreatic Adenosquamous Carcinoma

Genetic Tests for Pancreatic Adenosquamous Carcinoma

Anatomical Context for Pancreatic Adenosquamous Carcinoma

MalaCards organs/tissues related to Pancreatic Adenosquamous Carcinoma:

42
Pancreas, Salivary Gland

Publications for Pancreatic Adenosquamous Carcinoma

Articles related to Pancreatic Adenosquamous Carcinoma:

(show top 50) (show all 72)
# Title Authors Year
1
Long-term outcomes after an aggressive resection of adenosquamous carcinoma of the pancreas. ( 30980180 )
2019
2
"Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features: Erratum. ( 30985334 )
2019
3
A retroperitoneal mass confirmed as a pancreatic adenosquamous carcinoma by endoscopic ultrasound-guided fine-needle aspiration. ( 29069702 )
2018
4
Pancreatic adenosquamous carcinoma masquerading as a locally invading splenic abscess. ( 29740918 )
2018
5
Comparative outcomes of adenosquamous carcinoma of the pancreas: An analysis of the National Cancer Database. ( 29878370 )
2018
6
"Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features. ( 30138216 )
2018
7
PD-L1 expression in pancreatic adenosquamous carcinoma: PD-L1 expression is limited to the squamous component. ( 30477643 )
2018
8
Adenosquamous Carcinoma of the Pancreas Demonstrated on 18F-FDG PET/CT Imaging. ( 28098663 )
2017
9
Genomic signatures of pancreatic adenosquamous carcinoma (PASC). ( 28722109 )
2017
10
Clinical implications of the proliferative ability of the squamous component regarding tumor progression of adenosquamous carcinoma of the pancreas: A preliminary report. ( 28784574 )
2017
11
Recent advances in genomic profiling of adenosquamous carcinoma of the pancreas. ( 28816351 )
2017
12
Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a CDKN2A germline mutation carrier. ( 28979722 )
2017
13
A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet. ( 26863381 )
2016
14
Clinicopathological features and surgical outcomes of adenosquamous carcinoma of the pancreas: a retrospective analysis of patients with resectable stage tumors. ( 24973941 )
2015
15
Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report. ( 25674740 )
2015
16
Efficacy of platinum chemotherapy agents in the adjuvant setting for adenosquamous carcinoma of the pancreas. ( 25830031 )
2015
17
Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review. ( 26380056 )
2015
18
Adenosquamous Carcinoma of the Pancreas in a Patient with BRCA2 Mutation: A Case Report. ( 30631805 )
2015
19
Clinical characteristics of adenosquamous carcinoma of the pancreas: a matched case-control study. ( 24518509 )
2014
20
Ring-enhancement pattern on contrast-enhanced CT predicts adenosquamous carcinoma of the pancreas: a matched case-control study. ( 24854619 )
2014
21
The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. ( 24859531 )
2014
22
A huge adenosquamous carcinoma of the pancreas with sarcomatoid change: an unusual case report. ( 25473201 )
2014
23
Adenosquamous carcinoma of the pancreas: multidetector-row computed tomographic manifestations and tumor characteristics. ( 23493198 )
2013
24
Characteristics and outcomes of adenosquamous carcinoma of the pancreas. ( 23936547 )
2013
25
Contrast-enhanced multiphasic CT and MRI findings of adenosquamous carcinoma of the pancreas. ( 24035524 )
2013
26
Pancreatic adenosquamous carcinoma with 7-year survival: a case report and literature review. ( 23176255 )
2013
27
Splenomegaly as the first manifestation of pancreatic adenosquamous carcinoma: a case report. ( 23864460 )
2012
28
415 patients with adenosquamous carcinoma of the pancreas: a population-based analysis of prognosis and survival. ( 21816433 )
2012
29
Successful treatment with GEMOX in patient with metastatic pancreatic adenosquamous carcinoma. ( 21617724 )
2011
30
Pancreatic adenosquamous carcinoma presenting as splenic rupture: report of a case. ( 21626340 )
2011
31
Massive upper gastrointestinal hemorrhage due to adenosquamous carcinoma of the pancreas: Case report and literature review. ( 22811837 )
2011
32
Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patients. ( 19801164 )
2010
33
Electronic image of the month. Adenosquamous carcinoma of the pancreas. ( 20005983 )
2010
34
Adenosquamous carcinoma of the pancreas: a case report. ( 20205828 )
2010
35
Adenosquamous carcinoma of the pancreas: a distinct clinicopathologic entity. ( 20697320 )
2010
36
Adenosquamous carcinoma of the pancreas harbors KRAS2, DPC4 and TP53 molecular alterations similar to pancreatic ductal adenocarcinoma. ( 19270646 )
2009
37
Granulocyte-colony stimulating factor-producing pancreatic adenosquamous carcinoma showing aggressive clinical course. ( 19420814 )
2009
38
Adenosquamous carcinoma of the pancreas, a rare tumor entity: a case report. ( 20062646 )
2009
39
Complete response of a pancreatic adenosquamous carcinoma to chemoradiotherapy. ( 18307024 )
2008
40
Education of imaging. Hepatobiliary and pancreatic: adenosquamous carcinoma of the pancreas. ( 18410615 )
2008
41
Adenosquamous carcinoma of the pancreas: a single-institution experience comparing resection and palliative care. ( 18722942 )
2008
42
Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma. ( 18764955 )
2008
43
Adenosquamous carcinoma of the pancreas associated with humoral hypercalcemia of malignancy (HHM). ( 18836809 )
2008
44
Surgical outcome of adenosquamous carcinoma of the pancreas. ( 19058301 )
2008
45
Adenosquamous carcinoma of the pancreas with clear cell and rhabdoid components. A case report. ( 17495363 )
2007
46
Adenosquamous carcinoma of the pancreas with an acantholytic pattern together with osteoclast-like and pleomorphic giant cells. ( 16126885 )
2005
47
Adenosquamous carcinoma of the pancreas. ( 16172546 )
2005
48
Adenosquamous carcinoma of the pancreas: cytologic features in 14 cases. ( 14681946 )
2003
49
Adenosquamous carcinoma of the pancreas: preoperative diagnosis and molecular alterations. ( 14714256 )
2003
50
Adenosquamous carcinoma of the pancreas: a clinicopathologic series of 25 cases. ( 11353055 )
2001

Variations for Pancreatic Adenosquamous Carcinoma

Expression for Pancreatic Adenosquamous Carcinoma

Search GEO for disease gene expression data for Pancreatic Adenosquamous Carcinoma.

Pathways for Pancreatic Adenosquamous Carcinoma

Pathways related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.97 IFNA17 KRAS MAML2
2 10.57 IFNA17 KRAS

GO Terms for Pancreatic Adenosquamous Carcinoma

Biological processes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 8.96 KRAS PTHLH
2 positive regulation of cell proliferation GO:0008284 8.8 KRAS PTHLH SERPINB3

Sources for Pancreatic Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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