MCID: PNC127
MIFTS: 24

Pancreatic Adenosquamous Carcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Adenosquamous Carcinoma

MalaCards integrated aliases for Pancreatic Adenosquamous Carcinoma:

Name: Pancreatic Adenosquamous Carcinoma 12 15 17
Adenosquamous Carcinoma of the Pancreas 12
Adenosquamous Carcinoma of Pancreas 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5637
NCIt 51 C5721
UMLS 74 C1335299

Summaries for Pancreatic Adenosquamous Carcinoma

Disease Ontology : 12 A pancreatic ductal carcinoma that derives from squamous cells and gland-like cells.

MalaCards based summary : Pancreatic Adenosquamous Carcinoma, also known as adenosquamous carcinoma of the pancreas, is related to adenosquamous carcinoma and pancreatic ductal adenocarcinoma. An important gene associated with Pancreatic Adenosquamous Carcinoma is UPF1 (UPF1 RNA Helicase And ATPase), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Jak-Stat Signaling Pathway (sino). Affiliated tissues include pancreas and salivary gland, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Pancreatic Adenosquamous Carcinoma

Diseases related to Pancreatic Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 30.6 KRAS PTHLH
2 pancreatic ductal adenocarcinoma 10.0
3 adenocarcinoma 10.0
4 splenic abscess 10.0
5 mucoepidermoid carcinoma 10.0
6 splenomegaly 10.0
7 lung squamous cell carcinoma 9.6 KRAS PTHLH

Graphical network of the top 20 diseases related to Pancreatic Adenosquamous Carcinoma:



Diseases related to Pancreatic Adenosquamous Carcinoma

Symptoms & Phenotypes for Pancreatic Adenosquamous Carcinoma

GenomeRNAi Phenotypes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

27 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-117 9.85 KRAS
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.85 IFNA17
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.85 KRAS
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 9.85 IFNA17
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.85 KRAS
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-193 9.85 IFNA17 KRAS
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.85 IFNA17
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.85 IFNA17
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.85 KRAS
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.85 KRAS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.85 KRAS
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.85 IFNA17
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.85 KRAS
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-66 9.85 IFNA17 KRAS
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 9.85 IFNA17

Drugs & Therapeutics for Pancreatic Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Pancreatic Adenosquamous Carcinoma

Genetic Tests for Pancreatic Adenosquamous Carcinoma

Anatomical Context for Pancreatic Adenosquamous Carcinoma

MalaCards organs/tissues related to Pancreatic Adenosquamous Carcinoma:

42
Pancreas, Salivary Gland

Publications for Pancreatic Adenosquamous Carcinoma

Articles related to Pancreatic Adenosquamous Carcinoma:

(show all 24)
# Title Authors Year
1
A retroperitoneal mass confirmed as a pancreatic adenosquamous carcinoma by endoscopic ultrasound-guided fine-needle aspiration. ( 29069702 )
2018
2
Pancreatic adenosquamous carcinoma masquerading as a locally invading splenic abscess. ( 29740918 )
2018
3
"Pancreatic Mucoepidermoid Carcinoma" Is not a Pancreatic Counterpart of CRTC1/3-MAML2 Fusion Gene-related Mucoepidermoid Carcinoma of the Salivary Gland, and May More Appropriately be Termed Pancreatic Adenosquamous Carcinoma With Mucoepidermoid Carcinoma-like Features. ( 30138216 )
2018
4
PD-L1 expression in pancreatic adenosquamous carcinoma: PD-L1 expression is limited to the squamous component. ( 30477643 )
2018
5
Genomic signatures of pancreatic adenosquamous carcinoma (PASC). ( 28722109 )
2017
6
Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a<i>CDKN2A</i>germline mutation carrier. ( 28979722 )
2017
7
A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet. ( 26863381 )
2016
8
Salvage pancreaticoduodenectomy after complete response to chemoradiotherapy for a previously unresectable pancreatic adenosquamous carcinoma: a case report. ( 25674740 )
2015
9
Adenosquamous Carcinoma of the Pancreas in a Patient with BRCA2 Mutation: A Case Report. ( 30631805 )
2015
10
The UPF1 RNA surveillance gene is commonly mutated in pancreatic adenosquamous carcinoma. ( 24859531 )
2014
11
Clinical characteristics of adenosquamous carcinoma of the pancreas: a matched case-control study. ( 24518509 )
2014
12
Pancreatic adenosquamous carcinoma with 7-year survival: a case report and literature review. ( 23176255 )
2013
13
Splenomegaly as the first manifestation of pancreatic adenosquamous carcinoma: a case report. ( 23864460 )
2012
14
Successful treatment with GEMOX in patient with metastatic pancreatic adenosquamous carcinoma. ( 21617724 )
2011
15
Pancreatic adenosquamous carcinoma presenting as splenic rupture: report of a case. ( 21626340 )
2011
16
Resected pancreatic adenosquamous carcinoma: clinicopathologic review and evaluation of adjuvant chemotherapy and radiation in 38 patients. ( 19801164 )
2010
17
Granulocyte-colony stimulating factor-producing pancreatic adenosquamous carcinoma showing aggressive clinical course. ( 19420814 )
2009
18
Clinicopathologic features and outcomes following surgery for pancreatic adenosquamous carcinoma. ( 18764955 )
2008
19
Complete response of a pancreatic adenosquamous carcinoma to chemoradiotherapy. ( 18307024 )
2008
20
Education of imaging. Hepatobiliary and pancreatic: adenosquamous carcinoma of the pancreas. ( 18410615 )
2008
21
Adenosquamous carcinoma of the pancreas. ( 10597404 )
1999
22
FNAC guided by computed tomography in the diagnosis of primary pancreatic adenosquamous carcinoma. A report of three cases. ( 9850660 )
1998
23
Intraoperative cytodiagnosis of pancreatic adenosquamous carcinoma: a case report. ( 3522134 )
1986
24
&amp;quot;COLO 357,&amp;quot; a human pancreatic adenosquamous carcinoma: growth in artificial capillary culture and in nude mice. ( 6640542 )
1983

Variations for Pancreatic Adenosquamous Carcinoma

Expression for Pancreatic Adenosquamous Carcinoma

Search GEO for disease gene expression data for Pancreatic Adenosquamous Carcinoma.

Pathways for Pancreatic Adenosquamous Carcinoma

Pathways related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.63 IFNA17 KRAS MAML2
2 10.9 IFNA17 KRAS

GO Terms for Pancreatic Adenosquamous Carcinoma

Biological processes related to Pancreatic Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 female pregnancy GO:0007565 8.62 KRAS PTHLH

Sources for Pancreatic Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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