MCID: PNC038
MIFTS: 26

Pancreatic Cystadenocarcinoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Cystadenocarcinoma

MalaCards integrated aliases for Pancreatic Cystadenocarcinoma:

Name: Pancreatic Cystadenocarcinoma 12 15
Cystadenocarcinoma of Pancreas 12 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4073
NCIt 50 C3874
SNOMED-CT 67 235966007
UMLS 71 C0238337

Summaries for Pancreatic Cystadenocarcinoma

MalaCards based summary : Pancreatic Cystadenocarcinoma, also known as cystadenocarcinoma of pancreas, is related to pancreatic serous cystadenocarcinoma and cystadenocarcinoma, and has symptoms including abdominal pain, pruritus and icterus. An important gene associated with Pancreatic Cystadenocarcinoma is CEACAM5 (CEA Cell Adhesion Molecule 5), and among its related pathways/superpathways are MAPK Signaling: Oxidative Stress Pathway and Synthesis and interconversion of nucleotide di- and triphosphates. Affiliated tissues include pancreas, lymph node and spleen, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pancreatic Cystadenocarcinoma

Diseases related to Pancreatic Cystadenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 pancreatic serous cystadenocarcinoma 11.4
2 cystadenocarcinoma 10.6
3 mucinous cystadenocarcinoma 10.1
4 cystadenoma 10.0
5 mucinous cystadenocarcinoma of the pancreas 10.0
6 cervix carcinoma 10.0 MIR518A1 CEACAM5
7 serous cystadenocarcinoma 10.0
8 mucinous ovarian cystadenoma 10.0
9 crohn's disease 10.0
10 signet ring basal cell carcinoma 9.9 KRAS CEACAM5
11 immature teratoma of ovary 9.9 KRAS CEACAM5
12 mature teratoma 9.9 KRAS CEACAM5
13 teratoma 9.9 KRAS CEACAM5
14 urachal adenocarcinoma 9.9 KRAS CEACAM5
15 descending colon cancer 9.9 KRAS CEACAM5
16 rectosigmoid junction neoplasm 9.9 KRAS CEACAM5
17 transverse colon cancer 9.9 KRAS CEACAM5
18 sigmoid neoplasm 9.9 KRAS CEACAM5
19 appendiceal neoplasm 9.9 KRAS CEACAM5
20 appendix adenocarcinoma 9.9 KRAS CEACAM5
21 bile acid synthesis defect, congenital, 5 9.9 KRAS CEACAM5
22 ascending colon cancer 9.9 KRAS CEACAM5
23 biliary tract benign neoplasm 9.9 KRAS CEACAM5
24 ovarian mucinous neoplasm 9.9 KRAS CEACAM5
25 malignant exocrine pancreas neoplasm 9.9 KRAS CEACAM5
26 appendix disease 9.9 KRAS CEACAM5
27 bile duct cysts 9.9 KRAS CEACAM5
28 papillary adenoma 9.9 KRAS CEACAM5
29 appendix cancer 9.9 KRAS CEACAM5
30 duodenum adenocarcinoma 9.9 KRAS CEACAM5
31 eccrine papillary adenoma 9.9 KRAS CEACAM5
32 rectosigmoid cancer 9.9 KRAS CEACAM5
33 seminal vesicle adenocarcinoma 9.9 KRAS CEACAM5
34 anus cancer 9.9 KRAS CEACAM5
35 duodenum cancer 9.9 KRAS CEACAM5
36 duodenum disease 9.9 KRAS CEACAM5
37 papillary serous adenocarcinoma 9.9 KRAS CEACAM5
38 cecum carcinoma 9.9 KRAS CEACAM5
39 pseudomyxoma peritonei 9.9 KRAS CEACAM5
40 villous adenoma 9.9 KRAS CEACAM5
41 mixed cell type cancer 9.9 KRAS CEACAM5
42 leukemia, chronic lymphocytic 9.9
43 peutz-jeghers syndrome 9.9
44 pancreatic cancer 9.9
45 zollinger-ellison syndrome 9.9
46 polycystic kidney disease 9.9
47 constipation 9.9
48 thrombocytosis 9.9
49 splenic infarction 9.9
50 acute pancreatitis 9.9

Graphical network of the top 20 diseases related to Pancreatic Cystadenocarcinoma:



Diseases related to Pancreatic Cystadenocarcinoma

Symptoms & Phenotypes for Pancreatic Cystadenocarcinoma

UMLS symptoms related to Pancreatic Cystadenocarcinoma:


abdominal pain, pruritus, icterus

GenomeRNAi Phenotypes related to Pancreatic Cystadenocarcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-120 8.92 KRAS
2 Increased shRNA abundance (Z-score > 2) GR00366-A-204 8.92 TXN
3 Increased shRNA abundance (Z-score > 2) GR00366-A-22 8.92 KRAS
4 Increased shRNA abundance (Z-score > 2) GR00366-A-63 8.92 KRAS

Drugs & Therapeutics for Pancreatic Cystadenocarcinoma

Search Clinical Trials , NIH Clinical Center for Pancreatic Cystadenocarcinoma

Genetic Tests for Pancreatic Cystadenocarcinoma

Anatomical Context for Pancreatic Cystadenocarcinoma

MalaCards organs/tissues related to Pancreatic Cystadenocarcinoma:

40
Pancreas, Lymph Node, Spleen, Kidney, Thyroid, Ovary

Publications for Pancreatic Cystadenocarcinoma

Articles related to Pancreatic Cystadenocarcinoma:

(show top 50) (show all 69)
# Title Authors PMID Year
1
[Establishment and clinical testing of pancreatic cancer Faster R-CNN AI system based on fast regional convolutional neural network]. 61
32610422 2020
2
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in a patient with peritoneal carcinomatosis from a pancreatic cystadenocarcinoma: A case report. 61
31563663 2019
3
Pancreatic pseudocyst or mucinous cystadenocarcinoma of pancreas? A diagnostic dilemma. 61
28396777 2017
4
Diabetic ketoacidosis as the presenting manifestation of pancreatic adenocarcinoma with cystic features. 61
28345065 2017
5
Serous Microcystic Adenocarcinoma of Pancreas Infiltrating Into Spleen: A Case Report. 61
26500911 2015
6
[Value of intraoperative fine needle aspiration cytology in the diagnosis of pancreatic cancer]. 61
26463029 2015
7
Laparoscopic pancreaticoduodenectomy via a reverse-''V'' approach with four ports: initial experience and perioperative outcomes. 61
25663778 2015
8
Serous cystadenocarcinoma of pancreas. 61
23763806 2013
9
The application value of contrast-enhanced ultrasound in the differential diagnosis of pancreatic solid-cystic lesions. 61
21477957 2012
10
Preoperative gemcitabine and oxaliplatin in a patient with ovarian metastasis from pancreatic cystadenocarcinoma. 61
22949893 2012
11
[Mucinous cystadenocarcinoma of pancreas]. 61
21138674 2009
12
Laparoscopic pancreaticoduodenectomy: technique and outcomes. 61
17660068 2007
13
Mucinous cystadenocarcinoma of the pancreas diagnosed in postpartum. 61
17530280 2007
14
An extremely rare cause of acute abdomen in pregnancy: ruptured pancreatic mucinous cystadenocarcinoma. 61
17446849 2007
15
[A ninety-eight-year-old woman with ruptured pancreatic anaplastic mucinous cystadenocarcinoma]. 61
16683661 2006
16
Is there a role for chemoradiation in the management of cystadenocarcinoma of the pancreas? 61
15968257 2005
17
Metastatic lymph node impostor in pancreatic cystadenocarcinoma. 61
15767737 2005
18
[Pancreatic cystadenocarcinoma revealed by an acute pancreatitis and exploratory surgery. A rare case report]. 61
14608744 2003
19
Solitary pancreatic tuberculous abscess mimicking prancreatic cystadenocarcinoma: a case report. 61
12521381 2003
20
Endoscopic ultrasonography to study the causes of extragastric compression mimicking gastric submucosal tumor. 61
11802535 2001
21
C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET. 61
11494127 2001
22
Simultaneous mucinous cystadenoma of ovary and mucinous cystadenocarcinoma of pancreas. 61
11185714 2000
23
[Cerebrovascular accident as the form of presentation of a pancreatic cystadenocarcinoma: an unusual form of presentation in a rare tumor]. 61
10804692 2000
24
Expression of thioredoxin and glutaredoxin, redox-regulating proteins, in pancreatic cancer. 61
10757123 2000
25
Pancreatitis associated with Crohn's disease: a premalignant state for cystadenocarcinoma of pancreas? 61
10445570 1999
26
Analysis of K-ras gene mutations in rare pancreatic and ampullary tumours. 61
9895049 1998
27
Ductectatic mucinous cystadenocarcinoma of the pancreas: a rare variant. 61
9951933 1998
28
Lesser sac endoscopy and laparoscopy in pancreatic carcinoma definitive diagnosis, staging and palliation. 61
9731805 1998
29
Pancreatic cystadenocarcinoma in Peutz-Jeghers syndrome. 61
9412957 1997
30
Association between pancreatic cystadenocarcinoma, malignant liver cysts, and polycystic disease of the kidney. 61
9178704 1997
31
[Cystadenocarcinoma of the pancreas. Case report and review of the literature]. 61
9303632 1997
32
Cystic neoplasm mistaken for pancreatic pseudocyst. 61
8884322 1996
33
[Hemorrhagic pancreatic cystadenocarcinoma with colonic fistula. An unusual mode of manifestation]. 61
8761146 1996
34
Comparison between a newly established pancreatic cystadenocarcinoma cell-line, ocup-1 and cells derived from pancreatic ductal carcinoma. 61
21567058 1994
35
An alpha-fetoprotein producing pancreatic cystadenocarcinoma. 61
7522067 1994
36
Pylorus-preserving pancreatoduodenectomy. Is it an adequate cancer operation. 61
7908796 1994
37
Needle aspiration cytology in the diagnosis of mucinous cystadenocarcinoma of pancreas. A study of five cases with an emphasis on utility and differential diagnosis. 61
7520925 1994
38
Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas. 61
7902444 1993
39
Immunohistochemical study of pancreatic cystadenocarcinoma. 61
1728123 1992
40
[Giant cystadenocarcinoma of pancreatic origin and supra-mesocolic topography]. 61
1746873 1991
41
[A mucinous cystadenocarcinoma of the pancreas. A clinical and histopathological contribution]. 61
1866040 1991
42
[Serous cystadenoma and mucinous cystadenoma/cystadenocarcinoma of the pancreas. Clinical manifestation, diagnostic procedure and therapeutic concept]. 61
2204772 1990
43
Pancreatic cystadenocarcinoma and pregnancy: a case report. 61
2368178 1990
44
Cystadenocarcinoma of the pancreas: neo-adjuvant therapy and CEA monitoring. 61
2296199 1990
45
Two cases of pancreatic cystadenocarcinoma with elevated CA 19-9 levels in the cystic fluid in comparison with two cases of pancreatic cystadenoma. 61
2693299 1989
46
[Presentation of 6 cases of cystadenocarcinoma of the pancreas]. 61
2799037 1989
47
Unique appearance of the duodenal papilla in pancreatic cystadenocarcinoma. 61
2539985 1989
48
[Radiologic appearance of pancreatic cystadenocarcinoma]. 61
3070088 1988
49
[Endoscopic cystoduodenostomy of cystadenocarcinoma of pancreas]. 61
3582875 1987
50
[An autopsy performed on a pancreatic cystadenocarcinoma patient who received total pancreatectomy ten years ago]. 61
4057661 1985

Variations for Pancreatic Cystadenocarcinoma

Expression for Pancreatic Cystadenocarcinoma

Search GEO for disease gene expression data for Pancreatic Cystadenocarcinoma.

Pathways for Pancreatic Cystadenocarcinoma

Pathways related to Pancreatic Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.85 TXN KRAS
2 10.02 TXN GLRX

GO Terms for Pancreatic Cystadenocarcinoma

Biological processes related to Pancreatic Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell redox homeostasis GO:0045454 8.62 TXN GLRX

Molecular functions related to Pancreatic Cystadenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein disulfide oxidoreductase activity GO:0015035 8.62 TXN GLRX

Sources for Pancreatic Cystadenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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