MCID: PNC039
MIFTS: 33

Pancreatic Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreatic Cystadenoma

MalaCards integrated aliases for Pancreatic Cystadenoma:

Name: Pancreatic Cystadenoma 12 15
Cystadenoma of Pancreas 70

Classifications:



External Ids:

Disease Ontology 12 DOID:3918
NCIt 50 C4374
SNOMED-CT 67 235967003
UMLS 70 C0341486

Summaries for Pancreatic Cystadenoma

MalaCards based summary : Pancreatic Cystadenoma, also known as cystadenoma of pancreas, is related to insulinoma and pancreatic serous cystadenoma. An important gene associated with Pancreatic Cystadenoma is CEACAM5 (CEA Cell Adhesion Molecule 5), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Integration of energy metabolism. The drugs Ethanol and Anti-Infective Agents, Local have been mentioned in the context of this disorder. Affiliated tissues include pancreas, spleen and lymph node, and related phenotypes are endocrine/exocrine gland and homeostasis/metabolism

Related Diseases for Pancreatic Cystadenoma

Diseases related to Pancreatic Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 203)
# Related Disease Score Top Affiliating Genes
1 insulinoma 31.0 SSTR2 SST SLC2A2 PTPRN2 PTPRN MEN1
2 pancreatic serous cystadenoma 30.7 CHGA CEACAM5
3 adenoma 30.5 SSTR2 SST MEN1 CHGA
4 duodenal ulcer 30.4 SST INS GAST
5 pancreatitis 30.3 SST MIR21 INS GCG
6 microcystic adenoma 11.1
7 cystadenoma 10.8
8 liver lipoma 10.5 INS CEACAM5
9 vaginal glandular tumor 10.5 CHGA CEACAM5
10 jejunal somatostatinoma 10.5 SST PPY
11 pancreatic colloid cystadenoma 10.5 PTPRN GCG
12 vulvar eccrine porocarcinoma 10.5 CHGA CEACAM5
13 pancreatic serous cystadenocarcinoma 10.5 CHGA CEACAM5
14 adult teratoma 10.5 CHGA CEACAM5
15 autoimmune atrophic gastritis 10.5 GAST CHGA
16 vaginal tubulovillous adenoma 10.5 CHGA CEACAM5
17 cervical large cell neuroendocrine carcinoma 10.5 PTPRN CHGA
18 female urethral cancer 10.4 CHGA CEACAM5
19 pituitary infarct 10.4 SST MEN1 INS
20 ampulla of vater benign neoplasm 10.4 SST CHGA
21 acidophil adenoma 10.4 SST INS
22 papillary thymic adenocarcinoma 10.4 CHGA CEACAM5
23 mucinous ovarian cystadenoma 10.4 GAST CEACAM5
24 carotid body cancer 10.4 SST CHGA
25 auditory system benign neoplasm 10.4 PPY CHGA
26 pituitary apoplexy 10.4 SST MEN1 INS
27 rectum neuroendocrine neoplasm 10.4 SST GAST
28 gastric small cell carcinoma 10.4 CHGA CEACAM5
29 appendiceal neoplasm 10.4 CHGA CEACAM5
30 duodenal benign neoplasm 10.4 SST CHGA
31 hirata disease 10.4 SLC30A8 SLC30A10 INS
32 thyroid gland disease 10.4 SST INS CEACAM5
33 esophageal adenoid cystic carcinoma 10.4 CHGA CEACAM5
34 middle ear adenoma 10.4 PPY CHGA
35 mixed ductal-endocrine carcinoma 10.4 GAST CHGA
36 autonomic nervous system disease 10.4 PPY INS GCG
37 pancreatic somatostatinoma 10.4 SST PPY
38 laryngeal neuroendocrine tumor 10.4 SST CHGA
39 carcinoid syndrome 10.4 SST MEN1 CHGA
40 small intestine benign neoplasm 10.4 SST MEN1 CHGA
41 hypoglycemic coma 10.4 INS GCG
42 small intestine neuroendocrine neoplasm 10.4 SST MEN1
43 meckel diverticulum 10.4 SST GCG CHGA
44 nasopharyngitis 10.4 INS GLP1R GCG
45 abnormality of glucagon secretion 10.4 SST IAPP GCG
46 sensory organ benign neoplasm 10.4 PPY CHGA
47 type 1 diabetes mellitus 3 10.4 SLC30A8 SLC30A10
48 gastric hemangioma 10.4 SST CHGA
49 persistent generalized lymphadenopathy 10.4 MIR21 MEN1 CHGA
50 goblet cell carcinoid 10.4 GAST CHGA

Graphical network of the top 20 diseases related to Pancreatic Cystadenoma:



Diseases related to Pancreatic Cystadenoma

Symptoms & Phenotypes for Pancreatic Cystadenoma

MGI Mouse Phenotypes related to Pancreatic Cystadenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.7 CHGA GAD2 GAST GLP1R INS MEN1
2 homeostasis/metabolism MP:0005376 9.5 CHGA GAD2 GAST GLP1R IAPP INS

Drugs & Therapeutics for Pancreatic Cystadenoma

Drugs for Pancreatic Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 2, Phase 3 64-17-5 702
2 Anti-Infective Agents, Local Phase 2, Phase 3
3 Anti-Infective Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 EUS-Guided Pancreatic Injection of Cyst (EPIC) Trial Completed NCT00233038 Phase 2, Phase 3

Search NIH Clinical Center for Pancreatic Cystadenoma

Genetic Tests for Pancreatic Cystadenoma

Anatomical Context for Pancreatic Cystadenoma

MalaCards organs/tissues related to Pancreatic Cystadenoma:

40
Pancreas, Spleen, Lymph Node, Colon, Pancreatic Islet

Publications for Pancreatic Cystadenoma

Articles related to Pancreatic Cystadenoma:

(show top 50) (show all 137)
# Title Authors PMID Year
1
A case of multiple serous cystadenoma of pancreas. 61
33299562 2020
2
Laparoscopic Central Pancreatectomy with Pancreato-Gastric Anastomosis for Pancreatic Cystadenoma. 61
32876026 2020
3
[Establishment and clinical testing of pancreatic cancer Faster R-CNN AI system based on fast regional convolutional neural network]. 61
32610422 2020
4
Pancreatic schwannoma mimicking pancreatic cystadenoma: A case report and literature review of the imaging features. 61
31192973 2019
5
Serous Pancreatic Cystadenoma with Compression of Wirsung's Duct. 61
29736662 2019
6
Circulating microRNA-99 family as liquid biopsy marker in pancreatic adenocarcinoma. 61
30225540 2018
7
[Diagnosis and treatment experience of 161 cases of pancreatic serous cystic neoplasm in single center and analysis of cause of preoperation misjudgement]. 61
30107701 2018
8
Mucinous cystadenoma of pancreas with honeycombing appearance: Radiological-Pathological correlation. 61
30319210 2018
9
Anatomical segmentectomy of the pancreatic head along the embryological fusion plane: A case series and a literature review. 61
29718872 2018
10
Serous cystadenoma of pancreas: A clinicopathologic experience of 23 cases from a major tertiary care center. 61
30542522 2018
11
[Macrocystic serous cystadenoma of the pancreas, about a case]. 61
28525201 2017
12
Central pancreatectomy for pancreatic schwannoma: A case report and literature review. 61
27729750 2016
13
Serous cystadenoma of pancreas: imaging diagnosis. 61
26591957 2015
14
The application value of contrast-enhanced ultrasound in the differential diagnosis of pancreatic solid-cystic lesions. 61
21477957 2012
15
Laparoscopic resection of pancreatic cystadenomas. 61
23411805 2012
16
Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancer. 61
21719059 2011
17
Pancreatic and peri-pancreatic lesions mimic pancreatic islet cell tumor in multidetector computed tomography. 61
21740785 2011
18
Solid pseudopapillary epithelial neoplasm--a rare but curable pancreatic tumour in young women. 61
21614977 2011
19
[Middle segment pancreatectomy for the benign tumors of the neck and body of the pancreas (report of 15 cases)]. 61
21092576 2010
20
[Interventional radiology treatment for delayed pancreaticoduodenectomy hemorrhage]. 61
20979912 2010
21
CCL20/CCR6 expression profile in pancreatic cancer. 61
20459729 2010
22
[Microcystic serous pancreatic cystadenoma]. 61
20517831 2010
23
A rare complex association of pancreatic cystadenoma. 61
20182314 2010
24
Laparoscopic resection of a pancreatic serous cystadenoma preserving the integrity of main pancreatic duct: a case report. 61
19830064 2009
25
Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma. 61
19077459 2009
26
Diagnosis and therapeutic management of cystic dystrophy of the duodenal wall in heterotopic pancreas. A case report and revision of the literature. 61
18981555 2008
27
Seven years experience of pancreaticoduodenectomy at Sawanpracharak Hospital. 61
18839843 2008
28
Enhanced ENA-78 and IL-8 expression in patients with malignant pancreatic diseases. 61
18765953 2008
29
Left-sided portal hypertension caused by serous cystadenoma of the pancreas: report of a case. 61
18239883 2008
30
Role of cystic fluid in diagnosis of the pancreatic cystadenoma and cystadenocarcinoma. 61
18251127 2007
31
[Surgical treatment of giant serous cystadenoma of pancreas: report of two cases]. 61
17431440 2007
32
Laparoscopic resection of the pancreatic tail with splenic preservation. 61
16860642 2006
33
Pancreatic serous oligocystic adenomas: clinicopathologic features and a comparison with serous microcystic adenomas and mucinous cystic neoplasms. 61
16773248 2006
34
[Mucinous cystic tumour of the pancreas. A case report]. 61
16845875 2006
35
A case of cystic schwannoma of the lesser sac. 61
16470274 2006
36
Hormone-producing serous cystadenoma of the pancreas. 61
17167718 2006
37
Late follow-up of patients submitted to subtotal splenectomy. 61
17462342 2006
38
Late postoperative follow-up of patients undergoing subtotal splenectomy. 61
16358137 2005
39
Giant cystic abdominal masses in children. 61
16151789 2005
40
[Giant pancreatic cystadenoma. A very rare entity]. 61
16351469 2005
41
[Pancreas pseudocyst or metastasis?]. 61
16323569 2005
42
Expression of glycodelin in human breast cancer: immunohistochemical analysis in mammary carcinoma in situ, invasive carcinomas and their lymph node metastases. 61
16033096 2005
43
Risk factors of pancreatic leakage after pancreaticoduodenectomy. 61
15832417 2005
44
Pitfall in renal cyst surgery: serous cystadenoma of pancreas mimicking renal cyst. 61
15833547 2005
45
Surgical images: soft tissue. Müllerian cyst of the upper abdomen: a lesion mimicking pancreatic cystadenoma. 61
15540691 2004
46
Macrocystic pancreatic cystadenoma: The role of EUS and cyst fluid analysis in distinguishing mucinous and serous lesions. 61
15173795 2004
47
Surgical treatment for serous cystadenoma of pancreas--segmental pancreatectomy or conventional resection? 61
15086212 2004
48
Laparoscopy-assisted spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein. 61
15619015 2004
49
[Cystadenoma of the pancreas: 4 cases in our clinical experience]. 61
14725234 2003
50
[Laparoscopic segmental pancreas resection and pancreatic cystadenoma]. 61
14605740 2003

Variations for Pancreatic Cystadenoma

Expression for Pancreatic Cystadenoma

Search GEO for disease gene expression data for Pancreatic Cystadenoma.

Pathways for Pancreatic Cystadenoma

GO Terms for Pancreatic Cystadenoma

Cellular components related to Pancreatic Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 SST PPY MIR21 INS IAPP GCG
2 endoplasmic reticulum lumen GO:0005788 9.56 PTPRN2 MEN1 INS GCG
3 transport vesicle membrane GO:0030658 9.13 SLC30A8 PTPRN2 PTPRN
4 secretory granule GO:0030141 8.92 SLC30A8 PTPRN2 PTPRN CHGA

Biological processes related to Pancreatic Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.56 SSTR2 SST PPY INS IAPP GLP1R
2 regulation of insulin secretion GO:0050796 9.5 SLC2A2 GLP1R GCG
3 insulin secretion involved in cellular response to glucose stimulus GO:0035773 9.26 PTPRN2 PTPRN
4 negative regulation of blood vessel diameter GO:0097756 9.16 INS CHGA
5 negative regulation of reactive oxygen species biosynthetic process GO:1903427 8.8 SLC30A10 MIR21 INS

Molecular functions related to Pancreatic Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.1 SST PPY INS IAPP GCG GAST

Sources for Pancreatic Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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