MCID: PNC039
MIFTS: 25

Pancreatic Cystadenoma

Categories: Cancer diseases, Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Cystadenoma

MalaCards integrated aliases for Pancreatic Cystadenoma:

Name: Pancreatic Cystadenoma 12 15
Cystadenoma of Pancreas 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3918
NCIt 50 C4374
SNOMED-CT 68 235967003
UMLS 73 C0341486

Summaries for Pancreatic Cystadenoma

MalaCards based summary : Pancreatic Cystadenoma, also known as cystadenoma of pancreas, is related to cystadenoma and pancreatitis. An important gene associated with Pancreatic Cystadenoma is AKR7A2 (Aldo-Keto Reductase Family 7 Member A2), and among its related pathways/superpathways is Notch-mediated HES/HEY network. The drugs Ethanol and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include pancreas and spleen, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pancreatic Cystadenoma

Diseases related to Pancreatic Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 cystadenoma 10.5
2 pancreatitis 10.5
3 cystadenocarcinoma 10.0
4 cholangiocarcinoma 9.7
5 nephrotic syndrome 9.7
6 cholestasis 9.7
7 obstructive jaundice 9.7
8 pancreatic cystadenocarcinoma 9.7
9 biliary tract disease 9.7
10 splenomegaly 9.7
11 cytomegalovirus infection 9.7

Graphical network of the top 20 diseases related to Pancreatic Cystadenoma:



Diseases related to Pancreatic Cystadenoma

Symptoms & Phenotypes for Pancreatic Cystadenoma

GenomeRNAi Phenotypes related to Pancreatic Cystadenoma according to GeneCards Suite gene sharing:

26 (show all 19)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.64 SPEN
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.64 ALDOA
3 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.64 SPEN
4 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.64 ALDOA
5 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.64 ALDOA
6 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.64 ALDOA
7 Increased shRNA abundance (Z-score > 2) GR00366-A-137 9.64 ALDOA
8 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.64 AKR7A2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.64 SPEN
10 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.64 ALDOA
11 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.64 SPEN
12 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.64 ALDOA
13 Increased shRNA abundance (Z-score > 2) GR00366-A-195 9.64 SPEN
14 Increased shRNA abundance (Z-score > 2) GR00366-A-21 9.64 ALDOA
15 Increased shRNA abundance (Z-score > 2) GR00366-A-23 9.64 AKR7A2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.64 ALDOA
17 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.64 AKR7A2
18 Increased shRNA abundance (Z-score > 2) GR00366-A-82 9.64 AKR7A2
19 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.64 SPEN AKR7A2 ALDOA

Drugs & Therapeutics for Pancreatic Cystadenoma

Drugs for Pancreatic Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 2, Phase 3,Phase 1 64-17-5 702
2 Anti-Infective Agents Phase 2, Phase 3,Phase 1
3 Anti-Infective Agents, Local Phase 2, Phase 3,Phase 1
4 Central Nervous System Depressants Phase 2, Phase 3,Phase 1
5
Pancrelipase Approved, Investigational Phase 1 53608-75-6
6
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
7 Hemostatics Phase 1
8 pancreatin Phase 1
9 Albumin-Bound Paclitaxel Phase 1
10 Anti-Bacterial Agents Phase 1
11 Antibiotics, Antitubercular Phase 1
12 Antimitotic Agents Phase 1
13 Antineoplastic Agents, Phytogenic Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 EUS-Guided Pancreatic Injection of Cyst (EPIC) Trial Completed NCT00233038 Phase 2, Phase 3
2 Laser Tissue Welding - Distal Pancreatectomy Sealing Study Recruiting NCT03147768 Phase 1
3 Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm Terminated NCT01525706 Phase 1 Ethanol and Paclitaxel Injection

Search NIH Clinical Center for Pancreatic Cystadenoma

Genetic Tests for Pancreatic Cystadenoma

Anatomical Context for Pancreatic Cystadenoma

MalaCards organs/tissues related to Pancreatic Cystadenoma:

41
Pancreas, Spleen

Publications for Pancreatic Cystadenoma

Articles related to Pancreatic Cystadenoma:

(show all 32)
# Title Authors Year
1
Serous Pancreatic Cystadenoma with Compression of Wirsung's Duct. ( 29736662 )
2018
2
A rare complex association of pancreatic cystadenoma. ( 20182314 )
2010
3
Role of cystic fluid in diagnosis of the pancreatic cystadenoma and cystadenocarcinoma. ( 18251127 )
2007
4
Macrocystic pancreatic cystadenoma: The role of EUS and cyst fluid analysis in distinguishing mucinous and serous lesions. ( 15173795 )
2004
5
Surgical images: soft tissue. MA1llerian cyst of the upper abdomen: a lesion mimicking pancreatic cystadenoma. ( 15540691 )
2004
6
Stenosis of the common bile duct caused by synchronous pancreatic cystadenoma and cholangiocarcinoma. ( 12872115 )
2003
7
Macrocystic form of serous pancreatic cystadenoma. ( 12385440 )
2002
8
Hand-assisted laparoscopic distal pancreatectomy with minilaparotomy for distal pancreatic cystadenoma. ( 11330382 )
2001
9
Stricture of the main pancreatic duct due to focal pancreatitis coexistent with pancreatic cystadenoma. ( 10438172 )
1999
10
Hand-assisted laparoscopic distal pancreatectomy for pancreatic cystadenoma. ( 9649039 )
1998
11
Pancreatic tuberculosis: a rare condition mimicking pancreatic cystadenoma. ( 9788548 )
1998
12
Pancreatic cystadenoma and cystadenocarcinoma: diagnostic value of preoperative morphological investigations. ( 7727604 )
1995
13
Pancreatic cystadenoma associated with von Recklinghausen's disease. ( 1748501 )
1991
14
Two cases of pancreatic cystadenocarcinoma with elevated CA 19-9 levels in the cystic fluid in comparison with two cases of pancreatic cystadenoma. ( 2693299 )
1989
15
Pancreatic cystadenoma. A clinicopathologic study. ( 2818178 )
1989
16
Pancreatic cystadenoma in an infant: ultrastructural study. ( 3227008 )
1988
17
Neonatal cytomegalovirus infection with pancreatic cystadenoma and nephrotic syndrome. ( 3035523 )
1986
18
Pancreatic cystadenoma. Angiographic and histologic findings illustrated by two cases. ( 6463235 )
1984
19
Pancreatic cystadenoma with obstructive jaundice. ( 6719173 )
1984
20
Pancreatic cystadenoma and cystadenocarcinoma. ( 6722483 )
1984
21
Pancreatic cystadenoma in Von Hippel-Lindau disease: an unusual cause of pancreatic and common bile duct obstruction. ( 7161467 )
1982
22
Pancreatic cystadenoma. ( 7288697 )
1981
23
Benign pancreatic cystadenoma. ( 6973071 )
1981
24
A pancreatic cystadenoma complicated by varices: case report. ( 7362948 )
1980
25
Pancreatic cystadenoma of the spleen. ( 453461 )
1979
26
Pancreatic cystadenoma. A clinicopathologic study of 45 cases. ( 637722 )
1978
27
Haemobilia from pancreatic cystadenoma. ( 1080997 )
1975
28
Pancreatic cystadenoma and biliary tract disease. ( 5504218 )
1970
29
Pancreatic cystadenoma in childhood. Report of a case. ( 5803827 )
1969
30
Pancreatic cystadenoma: report of a case. ( 5638131 )
1968
31
PANCREATIC CYSTADENOMA WITH INTESTINAL HEMORRHAGE. ( 14068407 )
1963
32
Congestive splenomegaly due to pancreatic cystadenoma. ( 14935391 )
1952

Variations for Pancreatic Cystadenoma

Expression for Pancreatic Cystadenoma

Search GEO for disease gene expression data for Pancreatic Cystadenoma.

Pathways for Pancreatic Cystadenoma

Pathways related to Pancreatic Cystadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.3 PTF1A SPEN

GO Terms for Pancreatic Cystadenoma

Sources for Pancreatic Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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