MCID: PNC002
MIFTS: 37

Pancreatic Mucinous Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreatic Mucinous Cystadenoma

MalaCards integrated aliases for Pancreatic Mucinous Cystadenoma:

Name: Pancreatic Mucinous Cystadenoma 12 15 74
Pancreatic Mucinous Cystic Neoplasm 12
Pancreatic Mucinous-Cystic Neoplasm 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7235
NCIt 51 C41247

Summaries for Pancreatic Mucinous Cystadenoma

MalaCards based summary : Pancreatic Mucinous Cystadenoma, also known as pancreatic mucinous cystic neoplasm, is related to cystadenoma and kidney benign neoplasm. An important gene associated with Pancreatic Mucinous Cystadenoma is MME (Membrane Metalloendopeptidase), and among its related pathways/superpathways are Gastric cancer and O-linked glycosylation. The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include kidney, pancreas and thymus.

Related Diseases for Pancreatic Mucinous Cystadenoma

Diseases related to Pancreatic Mucinous Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 244)
# Related Disease Score Top Affiliating Genes
1 cystadenoma 30.7 KRT20 KRT7 MME MUC1 MUC2 PGR
2 kidney benign neoplasm 10.5 KRT7 MME
3 cervical mucinous adenocarcinoma 10.5 KRT7 MME
4 chronic orbital inflammation 10.5 MME MUC1
5 clear cell papillary renal cell carcinoma 10.5 KRT7 MME
6 parachordoma 10.5 KRT7 MUC1
7 spindle cell sarcoma 10.5 KRT7 MUC1
8 secretory meningioma 10.5 KRT7 MUC1
9 large intestine adenocarcinoma 10.5 KRT20 KRT7
10 jejunal adenocarcinoma 10.5 KRT20 KRT7
11 endocervical adenocarcinoma 10.5 KRT20 KRT7
12 middle ear adenoma 10.5 KRT7 MUC1
13 lipoadenoma 10.5 KRT7 MUC1
14 chronic cystitis 10.5 KRT20 KRT7
15 monophasic synovial sarcoma 10.5 KRT7 MUC1
16 thymus lipoma 10.5 KRT20 KRT7
17 linitis plastica 10.5 KRT20 KRT7
18 villous adenoma 10.5 KRT20 MUC1
19 medulloepithelioma 10.5 KRT20 KRT7
20 well-differentiated liposarcoma 10.5 KRT7 MUC1
21 renal pelvis carcinoma 10.5 KRT20 KRT7
22 duodenum adenocarcinoma 10.5 KRT7 MUC2
23 adenoid squamous cell carcinoma 10.5 KRT20 KRT7
24 gastric diffuse adenocarcinoma 10.5 KRT20 KRT7
25 lung acinar adenocarcinoma 10.5 KRT20 KRT7
26 intratubular embryonal carcinoma 10.5 KRT20 KRT7
27 small cell carcinoma of the bladder 10.5 KRT20 KRT7
28 tn polyagglutination syndrome 10.5 MUC1 MUC2
29 limbal stem cell deficiency 10.5 MUC1 MUC5AC
30 hidradenoma 10.4 KRT7 MUC1
31 filamentary keratitis 10.4 MUC1 MUC5AC
32 complete androgen insensitivity syndrome 10.4 MUC1 MUC5AC
33 polyposis, skin pigmentation, alopecia, and fingernail changes 10.4 MUC2 MUC5AC
34 superior mesenteric artery syndrome 10.4 MUC2 MUC5AC
35 cryptogenic organizing pneumonia 10.4 MUC1 MUC5B
36 lipid pneumonia 10.4 MUC1 MUC5B
37 breast benign neoplasm 10.4 MME PGR
38 thoracic benign neoplasm 10.4 MME PGR
39 endometrial stromal nodule 10.4 MME PGR
40 benign breast phyllodes tumor 10.4 MME PGR
41 adenosarcoma 10.4 MME PGR
42 cystic nephroma 10.4 MME PGR
43 cervical carcinosarcoma 10.4 MME PGR
44 corneal abscess 10.4 KRT7 PGR
45 endometrial stromal tumor 10.4 MME PGR
46 myxoid leiomyosarcoma 10.4 MME PGR
47 female reproductive endometrioid cancer 10.4 KRT7 PGR
48 papillary hidradenoma 10.4 MME PGR
49 breast secretory carcinoma 10.4 KRT7 PGR
50 balloon cell malignant melanoma 10.4 KRT7 MME

Graphical network of the top 20 diseases related to Pancreatic Mucinous Cystadenoma:



Diseases related to Pancreatic Mucinous Cystadenoma

Symptoms & Phenotypes for Pancreatic Mucinous Cystadenoma

Drugs & Therapeutics for Pancreatic Mucinous Cystadenoma

Drugs for Pancreatic Mucinous Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2,Phase 1 33069-62-4 36314
2 Albumin-Bound Paclitaxel Phase 2,Phase 1
3
Ethanol Approved Phase 1 64-17-5 702
4
Pancrelipase Approved, Investigational Phase 1 53608-75-6
5 pancreatin Phase 1
6 Anti-Infective Agents Phase 1
7 Central Nervous System Depressants Phase 1
8 Anti-Infective Agents, Local Phase 1
9 Antineoplastic Agents, Phytogenic Phase 1
10 Antibiotics, Antitubercular Phase 1
11 Antimitotic Agents Phase 1
12 Anti-Bacterial Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intracystic Injection of NanoPac® in Subjects With Mucinous Cystic Pancreatic Neoplasms Recruiting NCT03188991 Phase 2 NanoPac®
2 Endoscopic Ultrasonography-guided Double Ethanol Lavage for Pancreatic Cysts: a Prospective Cohort Study Unknown status NCT02213419 Phase 1 Endoscopic ultrasonography-guided double ethanol lavage
3 Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm Terminated NCT01525706 Phase 1 Ethanol and Paclitaxel Injection
4 Early Detection of Pancreatic Cystic Neoplasms Recruiting NCT02110498
5 Diagnosis of PCL With EUS-FNA and Cross-sectional Imaging - A Report of Accuracy Active, not recruiting NCT03884179
6 Needle-based Confocal Laser Endomicroscopy on Pancreatic Cystic Lesions Terminated NCT02494388

Search NIH Clinical Center for Pancreatic Mucinous Cystadenoma

Genetic Tests for Pancreatic Mucinous Cystadenoma

Anatomical Context for Pancreatic Mucinous Cystadenoma

MalaCards organs/tissues related to Pancreatic Mucinous Cystadenoma:

42
Kidney, Pancreas, Thymus, Appendix, Colon, Ovary, Prostate

Publications for Pancreatic Mucinous Cystadenoma

Articles related to Pancreatic Mucinous Cystadenoma:

(show all 37)
# Title Authors Year
1
Pancreatic mucinous cystadenoma doubly complicated by acute pancreatitis and retroperitoneal rupture. ( 30197176 )
2019
2
An osteoclast-like giant cell tumor embedded in the mural nodule of a pancreatic mucinous cystic neoplasm: A case report and literature review. ( 31008959 )
2019
3
Pancreatic Mucinous Cystadenoma Mimicking Intraductal Papillary Mucinous Neoplasm. ( 29998168 )
2018
4
The diagnosis of pancreatic mucinous cystic neoplasm and associated adenocarcinoma in males: An eight-institution study of 349 patients over 15 years. ( 28211072 )
2017
5
Patients with a resected pancreatic mucinous cystic neoplasm have a better prognosis than patients with an intraductal papillary mucinous neoplasm: A large single institution series. ( 28416122 )
2017
6
Pancreatic Mucinous Cystic Neoplasm Communicating with Main Pancreatic Duct: An Unrecognized Presentation of Pancreatic Mucinous Neoplasm? ( 29187489 )
2017
7
Pancreatic mucinous cystic neoplasm masquerading as pseudocyst. ( 30019020 )
2017
8
Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature. ( 27681503 )
2016
9
Pancreatic mucinous cystadenoma with serum CA 19-9 over 1,000,000 U/mL: a case report and review of the literature. ( 25888888 )
2015
10
Pancreatic mucinous cystadenoma of borderline malignancy associated with Clonorchis sinensis. ( 25995671 )
2015
11
Resection of the main trunk of the superior mesenteric vein without reconstruction during surgery for giant pancreatic mucinous cystadenoma: A case report. ( 26140011 )
2015
12
A critique on the article describing pancreatic mucinous cystic neoplasm size using CT volumetry, spherical and ellipsoid formulas: validation study. ( 25640795 )
2015
13
Pancreatic mucinous cystic neoplasm in a transgender patient. ( 26104783 )
2015
14
Education and Imaging: gastrointestinal: segmental portal hypertension caused by pancreatic mucinous cystadenoma. ( 25318380 )
2014
15
Pancreatic mucinous cystic neoplasm size using CT volumetry, spherical and ellipsoid formulas: validation study. ( 24413780 )
2014
16
Large pancreatic mucinous cystic neoplasm during pregnancy: what should be done?. ( 23343567 )
2013
17
Pancreatic mucinous cystic neoplasm with sarcomatous stroma metastasizing to liver: a case report and review of literature. ( 23688355 )
2013
18
Pancreatic mucinous cystic neoplasm in a male patient. ( 23183402 )
2012
19
Voluminous pancreatic mucinous cystadenoma in a non-pregnant woman with rheumatoid arthritis. ( 22737534 )
2011
20
Metachronous malignant composite phaeochromocytoma and pancreatic mucinous cystadenoma in a patient with neurofibromatosis type 1. ( 21233684 )
2011
21
Pancreatic mucinous cystadenoma in an adult with cystic fibrosis. ( 21856266 )
2011
22
Pancreatic mucinous cystic neoplasm of the main pancreatic duct. ( 21284448 )
2011
23
Education and imaging. Hepatobiliary and pancreatic: Mucinous cystadenoma of the biliary tree. ( 20594267 )
2010
24
Pancreatic mucinous cystadenoma at ultrasound acoustic radiation force impulse (ARFI) imaging. ( 20562580 )
2010
25
Pancreatic mucinous cystadenoma communicating with the main pancreatic duct on MRI. ( 19934064 )
2009
26
Epidermoid accessory splenic cyst masquerading as a pancreatic mucinous cystic neoplasm. ( 18633876 )
2008
27
Pancreatic mucinous cystadenoma. ( 18416355 )
2007
28
Human pancreatic mucinous cystadenoma is characterized by distinct mucin, cytokeratin and CD10 expression compared with intraductal papillary-mucinous adenoma. ( 16722930 )
2006
29
Contrast-enhanced ultrasonography in the characterization of pancreatic mucinous cystadenoma. ( 15284474 )
2004
30
Pancreatic mucinous cystic neoplasm defined by ovarian stroma: demographics, clinical features, and prevalence of cancer. ( 15551256 )
2004
31
Pancreatic mucinous cystadenoma associated with celiac disease and polycystic kidneys. Case report and short review of the literature. ( 12143249 )
2002
32
Pathologic quiz case: Female with episodic abdominal pain. Pathologic diagnosis: pancreatic mucinous cystadenoma. ( 11079039 )
2000
33
Laparoscopic resection of a pancreatic mucinous cystadenoma using laparosonic coagulating shears. ( 9918625 )
1999
34
A pancreatic mucinous cystadenoma in a man with mesenchymal stroma, expressing oestrogen and progesterone receptors. ( 9504865 )
1998
35
Pancreatic mucinous cystic neoplasm with sarcomatous stroma: a report of three cases. ( 8990143 )
1997
36
A case report of pancreatic mucinous cystadenoma in a patient receiving chronic hemodialysis. ( 9151203 )
1996
37
Variability in cyst fluid carcinoembryonic antigen level, fluid viscosity, amylase content, and cytologic findings among multiple loculi of a pancreatic mucinous cystic neoplasm. ( 7692722 )
1993

Variations for Pancreatic Mucinous Cystadenoma

Expression for Pancreatic Mucinous Cystadenoma

Search GEO for disease gene expression data for Pancreatic Mucinous Cystadenoma.

Pathways for Pancreatic Mucinous Cystadenoma

Pathways related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.29 HRAS MUC2 PGR WNT1
2
Show member pathways
11.82 MUC1 MUC2 MUC5AC MUC5B
3
Show member pathways
11.7 HRAS MUC2 MUC5AC MUC5B
4
Show member pathways
11.43 HRAS MUC1 MUC2 MUC5AC MUC5B
5
Show member pathways
11.42 MUC1 MUC2 MUC5AC MUC5B

GO Terms for Pancreatic Mucinous Cystadenoma

Cellular components related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.7 CEACAM5 KRT7 MME MUC1 MUC5AC MUC5B
2 cytoplasm GO:0005737 9.7 CALB2 EZH2 HRAS KRT20 KRT7 MME
3 Golgi lumen GO:0005796 9.02 MUC1 MUC2 MUC5AC MUC5B WNT1

Biological processes related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 O-glycan processing GO:0016266 9.26 MUC1 MUC2 MUC5AC MUC5B
2 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.02 HRAS MUC1 MUC2 MUC5AC MUC5B

Sources for Pancreatic Mucinous Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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