MCID: PNC002
MIFTS: 32

Pancreatic Mucinous Cystadenoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreatic Mucinous Cystadenoma

MalaCards integrated aliases for Pancreatic Mucinous Cystadenoma:

Name: Pancreatic Mucinous Cystadenoma 12 15 70
Pancreatic Mucinous Cystic Neoplasm 12
Pancreatic Mucinous-Cystic Neoplasm 70

Classifications:



External Ids:

Disease Ontology 12 DOID:7235
NCIt 50 C41247
UMLS 70 C1335309 C1518872

Summaries for Pancreatic Mucinous Cystadenoma

MalaCards based summary : Pancreatic Mucinous Cystadenoma, also known as pancreatic mucinous cystic neoplasm, is related to adenoma and mucinous cystadenocarcinoma. An important gene associated with Pancreatic Mucinous Cystadenoma is MUC5AC (Mucin 5AC, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are CLEC7A (Dectin-1) signaling and O-linked glycosylation. The drugs Paclitaxel and Albumin-Bound Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include breast, pancreas and kidney.

Related Diseases for Pancreatic Mucinous Cystadenoma

Diseases related to Pancreatic Mucinous Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 411)
# Related Disease Score Top Affiliating Genes
1 adenoma 29.9 MUC5AC MUC1 KRT7 KRT20
2 mucinous cystadenocarcinoma 29.6 MUC1 KRT7 KRT20 CEACAM5
3 polycystic liver disease 1 with or without kidney cysts 29.3 MUC1 KRT7 KRT20 CEACAM5 CALB2
4 cystadenoma 29.1 PGR MUC5AC MUC1 MME KRT7 KRT20
5 cystadenocarcinoma 28.8 PGR MUC5AC MUC2 MUC1 KRT7 CEACAM5
6 colloid carcinoma of the pancreas 10.3 MUC5AC MUC1
7 bladder lymphoma 10.3 MME KRT20
8 pancreatic signet ring cell adenocarcinoma 10.3 MUC5AC MUC1
9 intrahepatic biliary papillomatosis 10.3 MUC5AC MUC1
10 chronic ethmoiditis 10.3 MUC5AC MUC1
11 bile duct mucinous adenocarcinoma 10.3 MUC5AC MUC1
12 anal gland adenocarcinoma 10.3 MUC5AC KRT7
13 anus adenocarcinoma 10.3 MUC5AC KRT7
14 filamentary keratitis 10.2 MUC5AC MUC1
15 subareolar duct papillomatosis 10.2 MME KRT7
16 cervical mucinous adenocarcinoma 10.2 MME KRT7
17 nipple benign neoplasm 10.2 MME KRT7
18 wolffian duct adenoma 10.2 MME KRT7
19 limbal stem cell deficiency 10.2 MUC5AC MUC1
20 nephrogenic adenoma 10.2 MUC1 KRT7
21 spiradenoma 10.2 MUC1 KRT7
22 mixed epithelial stromal tumour 10.2 MME KRT7
23 colorectal cancer, hereditary nonpolyposis, type 8 10.2 MUC5AC MUC1
24 bladder benign neoplasm 10.2 KRT7 KRT20
25 clear cell papillary renal cell carcinoma 10.2 MME KRT7
26 chromophil adenoma of the kidney 10.2 MME KRT7
27 cap polyposis 10.2 MUC5AC MUC2
28 atrophic vulva 10.2 KRT7 KRT20
29 orbital cellulitis 10.2 MME KRT7
30 balloon cell malignant melanoma 10.2 MME KRT7
31 cystitis cystica 10.2 KRT7 KRT20
32 pulmonary artery leiomyosarcoma 10.2 MME KRT7
33 endobronchial lipoma 10.2 MUC5AC KRT7
34 scrotum paget's disease 10.2 MUC1 KRT7
35 urinary bladder small cell neuroendocrine carcinoma 10.2 KRT7 KRT20
36 eyelid carcinoma 10.2 KRT7 KRT20
37 jejunal neoplasm 10.2 KRT7 KRT20
38 jejunal cancer 10.2 KRT7 KRT20
39 gallbladder signet ring cell adenocarcinoma 10.2 MUC1 KRT7
40 intratubular embryonal carcinoma 10.2 KRT7 KRT20
41 ovarian large-cell neuroendocrine carcinoma 10.2 KRT7 KRT20
42 papillary transitional carcinoma 10.2 KRT7 KRT20
43 appendix adenocarcinoma 10.2 KRT7 KRT20
44 supine hypotensive syndrome 10.2 KRT7 KRT20
45 mucinous bronchioloalveolar adenocarcinoma 10.2 KRT7 KRT20
46 acute pancreatitis 10.2
47 pancreatitis 10.2
48 jejunal adenocarcinoma 10.2 KRT7 KRT20
49 meibomian cyst 10.2 KRT7 KRT20
50 renal adenoma 10.2 MME KRT7

Graphical network of the top 20 diseases related to Pancreatic Mucinous Cystadenoma:



Diseases related to Pancreatic Mucinous Cystadenoma

Symptoms & Phenotypes for Pancreatic Mucinous Cystadenoma

Drugs & Therapeutics for Pancreatic Mucinous Cystadenoma

Drugs for Pancreatic Mucinous Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2 Albumin-Bound Paclitaxel Phase 2
3
Pancrelipase Approved, Investigational Phase 1 53608-75-6
4
Ethanol Approved Phase 1 64-17-5 702
5 pancreatin Phase 1
6 Tubulin Modulators Phase 1
7 Anti-Infective Agents, Local Phase 1
8 Antimitotic Agents Phase 1
9 Anti-Bacterial Agents Phase 1
10 Antibiotics, Antitubercular Phase 1
11 Anti-Infective Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Trial Evaluating Escalating Doses and the Safety of Intracystic Injection of NanoPac® in Subjects With Mucinous Cystic Pancreatic Neoplasms Completed NCT03188991 Phase 2 NanoPac®
2 EUS-guided Double Ethanol Lavage for Pancreatic Cysts: a Prospective Cohort Study Unknown status NCT02213419 Phase 1 Endoscopic ultrasonography-guided double ethanol lavage
3 EUS Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm Terminated NCT01525706 Phase 1 Ethanol and Paclitaxel Injection

Search NIH Clinical Center for Pancreatic Mucinous Cystadenoma

Genetic Tests for Pancreatic Mucinous Cystadenoma

Anatomical Context for Pancreatic Mucinous Cystadenoma

MalaCards organs/tissues related to Pancreatic Mucinous Cystadenoma:

40
Breast, Pancreas, Kidney, Liver, Lung, Ovary, Appendix

Publications for Pancreatic Mucinous Cystadenoma

Articles related to Pancreatic Mucinous Cystadenoma:

(show top 50) (show all 85)
# Title Authors PMID Year
1
A nomogram for predicting pancreatic mucinous cystic neoplasm and serous cystic neoplasm. 61
33748881 2021
2
Formation of a splenic artery aneurysm within a pancreatic mucinous cystic neoplasm. 61
33217145 2020
3
Pancreatic mesothelial cyst. 61
33028569 2020
4
The Utility of Endoscopic Ultrasound Fine Needle Aspiration in Pancreatic Cystic Lesions Diagnosis. 61
32707780 2020
5
Clinical diagnosis and management of pancreatic mucinous cystadenoma and cystadenocarcinoma: Single-center experience with 82 patients. 61
32699579 2020
6
Giant pancreatic mucinous cystadenoma masquerading as renal hydatid disease. 61
32565660 2020
7
A case of ruptured mucinous cystadenoma of the pancreas with recurrence-free survival for 8 years. 61
32185526 2020
8
Preoperative differentiation of pancreatic mucinous cystic neoplasm from macrocystic serous cystic adenoma using radiomics: Preliminary findings and comparison with radiological model. 61
31760275 2020
9
Gastric duplication cyst lined by pseudostratified columnar ciliated epithelium masquerading as a pancreatic mucinous cystic neoplasm: a case report and literature review. 61
32355528 2020
10
Differential diagnosis of pancreatic serous cystadenoma and mucinous cystadenoma: utility of textural features in combination with morphological characteristics. 61
31842793 2019
11
[Characteristics of pancreatic mucinous cystic neoplasm in patients treated at a National Hospital in Peru]. 61
31967260 2019
12
A pancreatic mucinous cystic neoplasm undergoing intriguing morphological changes over time and associated with recurrent pancreatitis: A case report. 61
31305468 2019
13
An osteoclast-like giant cell tumor embedded in the mural nodule of a pancreatic mucinous cystic neoplasm: A case report and literature review. 61
31008959 2019
14
Pancreatic mucinous cystadenoma doubly complicated by acute pancreatitis and retroperitoneal rupture. 61
30197176 2019
15
Discrimination of Pancreatic Serous Cystadenomas From Mucinous Cystadenomas With CT Textural Features: Based on Machine Learning. 61
31245294 2019
16
Pancreatic Mucinous Cystadenoma Mimicking Intraductal Papillary Mucinous Neoplasm. 61
29998168 2018
17
Diagnosis, morphopathological profile and treatment of mucinous cystadenoma of the pancreas - a single center experience. 61
30845296 2018
18
Pancreatic Mucinous Cystic Neoplasm Communicating with Main Pancreatic Duct: An Unrecognized Presentation of Pancreatic Mucinous Neoplasm? 61
29187489 2017
19
Pancreatic mucinous cystic neoplasm masquerading as pseudocyst. 61
30019020 2017
20
The diagnosis of pancreatic mucinous cystic neoplasm and associated adenocarcinoma in males: An eight-institution study of 349 patients over 15 years. 61
28211072 2017
21
Patients with a resected pancreatic mucinous cystic neoplasm have a better prognosis than patients with an intraductal papillary mucinous neoplasm: A large single institution series. 61
28416122 2017
22
Anaplastic Pancreatic Carcinoma Arising Within a Mucinous Cystic Neoplasm of the Pancreas: A Case Report and a Brief Review of the Literature. 61
30631840 2017
23
[Pancreatic mucinous cystadenoma doubly complicated by acute pancreatitis and retroperitoneal rupture]. 61
29610641 2017
24
Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature. 61
27681503 2016
25
Mucinous cystic neoplasm of the pancreas activated during pregnancy. 61
26943381 2015
26
An indeterminate mucin-producing cystic neoplasm containing an undifferentiated carcinoma with osteoclast-like giant cells: a case report of a rare association of pancreatic tumors. 61
26581412 2015
27
Pancreatic mucinous cystic neoplasm in a transgender patient. 61
26104783 2015
28
Resection of the main trunk of the superior mesenteric vein without reconstruction during surgery for giant pancreatic mucinous cystadenoma: A case report. 61
26140011 2015
29
Pancreatic mucinous cystadenoma of borderline malignancy associated with Clonorchis sinensis. 61
25995671 2015
30
Pancreatic mucinous cystadenoma with serum CA 19-9 over 1,000,000 U/mL: a case report and review of the literature. 61
25888888 2015
31
A critique on the article describing pancreatic mucinous cystic neoplasm size using CT volumetry, spherical and ellipsoid formulas: validation study. 61
25640795 2015
32
Education and Imaging: gastrointestinal: segmental portal hypertension caused by pancreatic mucinous cystadenoma. 61
25318380 2014
33
A case of pancreatic mucinous cystic neoplasm that enlarged during pregnancy and was resected after childbirth. 61
25195964 2014
34
Intraductal papillary neoplasms and mucinous cystic neoplasms of the hepatobiliary system: demographic differences between Asian and Western populations, and comparison with pancreatic counterparts. 61
24456415 2014
35
Laparoscopic spleen-preserving distal pancreatectomy with intraoperative vascular repair. 61
24380982 2014
36
Mucinous Cystic Neoplasms of Pancreas. 61
27785269 2014
37
Activated wnt signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms. 61
24067880 2014
38
Pancreatic mucinous cystic neoplasm size using CT volumetry, spherical and ellipsoid formulas: validation study. 61
24413780 2014
39
Mucinous cystic neoplasm in heterotopic pancreas presenting as colonic polyp. 61
24216559 2013
40
Pancreatic mucinous cystic neoplasm with sarcomatous stroma metastasizing to liver: a case report and review of literature. 61
23688355 2013
41
Cyst fluid carcinoembryonic antigen concentration and cytology by endosonography-guided fine needle aspiration in predicting malignant pancreatic mucinous cystic neoplasms. 61
23280287 2013
42
Large pancreatic mucinous cystic neoplasm during pregnancy: what should be done?. 61
23343567 2013
43
Immunohistochemical characteristics and malignant progression of hepatic cystic neoplasms in comparison with pancreatic counterparts. 61
22705005 2012
44
Pancreatic mucinous cystic neoplasm in a male patient. 61
23183402 2012
45
Pancreatic mucinous cystadenoma in an adult with cystic fibrosis. 61
21856266 2011
46
Cystic tumors of the liver: on the problems of diagnostic criteria. 61
21925800 2011
47
Voluminous pancreatic mucinous cystadenoma in a non-pregnant woman with rheumatoid arthritis. 61
22737534 2011
48
Metachronous malignant composite phaeochromocytoma and pancreatic mucinous cystadenoma in a patient with neurofibromatosis type 1. 61
21233684 2011
49
Pancreatic mucinous cystic neoplasm of the main pancreatic duct. 61
21284448 2011
50
Management of mucinous cystic neoplasms of the pancreas. 61
21128317 2010

Variations for Pancreatic Mucinous Cystadenoma

Expression for Pancreatic Mucinous Cystadenoma

Search GEO for disease gene expression data for Pancreatic Mucinous Cystadenoma.

Pathways for Pancreatic Mucinous Cystadenoma

GO Terms for Pancreatic Mucinous Cystadenoma

Cellular components related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 9.13 MUC5AC MUC2 MUC1
2 mucus layer GO:0070701 8.62 MUC5AC MUC2

Biological processes related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.13 MUC5AC MUC2 MUC1
2 O-glycan processing GO:0016266 8.8 MUC5AC MUC2 MUC1

Sources for Pancreatic Mucinous Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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