MCID: PNC002
MIFTS: 36

Pancreatic Mucinous Cystadenoma

Categories: Cancer diseases, Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Mucinous Cystadenoma

MalaCards integrated aliases for Pancreatic Mucinous Cystadenoma:

Name: Pancreatic Mucinous Cystadenoma 12 15 73
Pancreatic Mucinous Cystic Neoplasm 12
Pancreatic Mucinous-Cystic Neoplasm 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7235
NCIt 50 C41247
UMLS 73 C1518872

Summaries for Pancreatic Mucinous Cystadenoma

MalaCards based summary : Pancreatic Mucinous Cystadenoma, also known as pancreatic mucinous cystic neoplasm, is related to cystadenoma and balloon cell malignant melanoma. An important gene associated with Pancreatic Mucinous Cystadenoma is MUC2 (Mucin 2, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are Gastric cancer and O-linked glycosylation. The drugs Paclitaxel and Ethanol have been mentioned in the context of this disorder. Affiliated tissues include kidney, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Pancreatic Mucinous Cystadenoma

Diseases related to Pancreatic Mucinous Cystadenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 261)
# Related Disease Score Top Affiliating Genes
1 cystadenoma 30.3 KRT20 KRT7 MME MUC1 MUC2 PGR
2 balloon cell malignant melanoma 11.0 KRT7 MME
3 solid adenocarcinoma with mucin production 10.9 KRT7 MUC1
4 pancreatic intraductal papillary-mucinous neoplasm 10.9 MUC1 MUC2
5 cervical adenoma malignum 10.9 KRT7 MME
6 tumor of exocrine pancreas 10.9 MUC1 MUC2
7 mucinous intrahepatic cholangiocarcinoma 10.9 MUC2 MUC5AC
8 cystic basal cell carcinoma 10.9 KRT20 KRT7
9 cap polyposis 10.9 MUC2 MUC5AC
10 vaginal benign neoplasm 10.9 KRT20 KRT7
11 seminal vesicle adenocarcinoma 10.9 KRT20 KRT7
12 transverse colon cancer 10.9 KRT20 KRT7
13 appendix adenocarcinoma 10.9 KRT20 KRT7
14 ovarian large-cell neuroendocrine carcinoma 10.9 KRT20 KRT7
15 vaginal adenoma 10.9 KRT20 KRT7
16 vaginal tubulovillous adenoma 10.9 KRT20 KRT7
17 cervical mucinous adenocarcinoma 10.9 KRT7 MME
18 eyelid neoplasm 10.9 KRT20 KRT7
19 glandular cystitis 10.9 KRT20 KRT7
20 malignant syringoma 10.9 KRT20 KRT7
21 clear cell papillary renal cell carcinoma 10.9 KRT7 MME
22 parachordoma 10.9 KRT7 MUC1
23 krukenberg carcinoma 10.9 KRT20 KRT7
24 middle ear adenoma 10.9 KRT7 MUC1
25 large intestine adenocarcinoma 10.9 KRT20 KRT7
26 linitis plastica 10.9 KRT20 KRT7
27 lung acinar adenocarcinoma 10.9 KRT20 KRT7
28 small cell carcinoma of the bladder 10.9 KRT20 KRT7
29 adenoid squamous cell carcinoma 10.8 KRT20 KRT7
30 eccrine sweat gland neoplasm 10.8 KRT20 KRT7
31 intratubular embryonal carcinoma 10.8 KRT20 KRT7
32 monophasic synovial sarcoma 10.8 KRT7 MUC1
33 nephrogenic adenoma 10.8 KRT7 MUC1
34 encapsulated thymoma 10.8 MME MUC5B
35 gastric diffuse adenocarcinoma 10.8 KRT20 KRT7
36 female reproductive endometrioid cancer 10.7 KRT7 PGR
37 benign breast phyllodes tumor 10.7 MME PGR
38 spiradenoma 10.7 KRT7 MUC1
39 adenomyoma 10.7 KRT7 MME MUC1
40 ovarian mucinous adenocarcinoma 10.7 KRT20 KRT7 MUC2
41 benign metastasizing leiomyoma 10.7 KRT7 PGR
42 clear cell meningioma 10.7 MUC1 PGR
43 bladder lymphoma 10.7 KRT20 KRT7 MME
44 cystic teratoma 10.7 KRT20 KRT7 MUC2
45 jejunal adenocarcinoma 10.7 KRT20 KRT7
46 small intestine cancer 10.7 KRT20 KRT7 MUC2
47 oncocytoma 10.7 KRT7 MME MUC1
48 chronic cystitis 10.7 KRT20 KRT7
49 gastrointestinal carcinoma 10.7 KRT20 MUC1 MUC2
50 paget disease, extramammary 10.6 KRT20 KRT7 MUC1

Graphical network of the top 20 diseases related to Pancreatic Mucinous Cystadenoma:



Diseases related to Pancreatic Mucinous Cystadenoma

Symptoms & Phenotypes for Pancreatic Mucinous Cystadenoma

MGI Mouse Phenotypes related to Pancreatic Mucinous Cystadenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 ESR1 EZH2 HRAS KRT7 MME MUC2
2 immune system MP:0005387 9.61 ESR1 EZH2 MME MUC2 MUC5AC MUC5B
3 neoplasm MP:0002006 9.1 EZH2 HRAS MUC2 PGR PTF1A ESR1

Drugs & Therapeutics for Pancreatic Mucinous Cystadenoma

Drugs for Pancreatic Mucinous Cystadenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
2
Ethanol Approved Phase 1 64-17-5 702
3 Central Nervous System Depressants Phase 1
4 Albumin-Bound Paclitaxel Phase 1
5 Anti-Bacterial Agents Phase 1
6 Antibiotics, Antitubercular Phase 1
7 Anti-Infective Agents Phase 1
8 Anti-Infective Agents, Local Phase 1
9 Antimitotic Agents Phase 1
10 Antineoplastic Agents, Phytogenic Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm Terminated NCT01525706 Phase 1 Ethanol and Paclitaxel Injection

Search NIH Clinical Center for Pancreatic Mucinous Cystadenoma

Genetic Tests for Pancreatic Mucinous Cystadenoma

Anatomical Context for Pancreatic Mucinous Cystadenoma

MalaCards organs/tissues related to Pancreatic Mucinous Cystadenoma:

41
Kidney

Publications for Pancreatic Mucinous Cystadenoma

Articles related to Pancreatic Mucinous Cystadenoma:

(show all 19)
# Title Authors Year
1
Pancreatic mucinous cystadenoma of borderline malignancy associated with Clonorchis sinensis. ( 25995671 )
2015
2
Pancreatic mucinous cystadenoma with serum CA 19-9 over 1,000,000 U/mL: a case report and review of the literature. ( 25888888 )
2015
3
Resection of the main trunk of the superior mesenteric vein without reconstruction during surgery for giant pancreatic mucinous cystadenoma: A case report. ( 26140011 )
2015
4
Gastrointestinal: Segmental portal hypertension caused by pancreatic mucinous cystadenoma. ( 25318380 )
2014
5
Voluminous pancreatic mucinous cystadenoma in a non-pregnant woman with rheumatoid arthritis. ( 22737534 )
2011
6
Pancreatic mucinous cystadenoma in an adult with cystic fibrosis. ( 21856266 )
2011
7
Metachronous malignant composite phaeochromocytoma and pancreatic mucinous cystadenoma in a patient with neurofibromatosis type 1. ( 21233684 )
2011
8
Education and imaging. Hepatobiliary and pancreatic: Mucinous cystadenoma of the biliary tree. ( 20594267 )
2010
9
Pancreatic mucinous cystadenoma at ultrasound acoustic radiation force impulse (ARFI) imaging. ( 20562580 )
2010
10
Pancreatic mucinous cystadenoma communicating with the main pancreatic duct on MRI. ( 19934064 )
2009
11
Pancreatic mucinous cystadenoma. ( 18416355 )
2007
12
Human pancreatic mucinous cystadenoma is characterized by distinct mucin, cytokeratin and CD10 expression compared with intraductal papillary-mucinous adenoma. ( 16722930 )
2006
13
Contrast-enhanced ultrasonography in the characterization of pancreatic mucinous cystadenoma. ( 15284474 )
2004
14
Mucinous cystadenoma with mesenchymal over-growth: a new variant among pancreatic mucinous cystadenomas? ( 15221374 )
2004
15
Pancreatic mucinous cystadenoma associated with celiac disease and polycystic kidneys. Case report and short review of the literature. ( 12143249 )
2002
16
Pathologic quiz case: Female with episodic abdominal pain. Pathologic diagnosis: pancreatic mucinous cystadenoma. ( 11079039 )
2000
17
Laparoscopic resection of a pancreatic mucinous cystadenoma using laparosonic coagulating shears. ( 9918625 )
1999
18
A pancreatic mucinous cystadenoma in a man with mesenchymal stroma, expressing oestrogen and progesterone receptors. ( 9504865 )
1998
19
A case report of pancreatic mucinous cystadenoma in a patient receiving chronic hemodialysis. ( 9151203 )
1996

Variations for Pancreatic Mucinous Cystadenoma

Expression for Pancreatic Mucinous Cystadenoma

Search GEO for disease gene expression data for Pancreatic Mucinous Cystadenoma.

Pathways for Pancreatic Mucinous Cystadenoma

GO Terms for Pancreatic Mucinous Cystadenoma

Cellular components related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.73 CALB2 ESR1 EZH2 HRAS KRT20 KRT7
2 Golgi lumen GO:0005796 9.02 MUC1 MUC2 MUC5AC MUC5B WNT1

Biological processes related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.46 ESR1 EZH2 HRAS PGR
2 protein localization to chromatin GO:0071168 9.26 ESR1 EZH2
3 O-glycan processing GO:0016266 9.26 MUC1 MUC2 MUC5AC MUC5B
4 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.02 HRAS MUC1 MUC2 MUC5AC MUC5B

Molecular functions related to Pancreatic Mucinous Cystadenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 8.92 ESR1 EZH2 MUC1 PGR

Sources for Pancreatic Mucinous Cystadenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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