MCID: PNC028
MIFTS: 31

Pancreatic Steatorrhea

Categories: Endocrine diseases, Gastrointestinal diseases

Aliases & Classifications for Pancreatic Steatorrhea

MalaCards integrated aliases for Pancreatic Steatorrhea:

Name: Pancreatic Steatorrhea 12 15 73
Pancreatic Steatorrhoea 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10610
ICD10 33 K90.3
ICD9CM 35 579.4
SNOMED-CT 68 54576000
UMLS 73 C0152166

Summaries for Pancreatic Steatorrhea

MalaCards based summary : Pancreatic Steatorrhea, also known as pancreatic steatorrhoea, is related to steatorrhea and pancreatitis. An important gene associated with Pancreatic Steatorrhea is GFPT2 (Glutamine-Fructose-6-Phosphate Transaminase 2), and among its related pathways/superpathways are Pancreatic secretion and Alanine, aspartate and glutamate metabolism. Affiliated tissues include testes, pancreas and skin.

Related Diseases for Pancreatic Steatorrhea

Diseases related to Pancreatic Steatorrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 92)
# Related Disease Score Top Affiliating Genes
1 steatorrhea 30.8 SCT PNLIP CELA1 CCK
2 pancreatitis 30.1 SCT PRSS1 PNLIP CTSB CCK
3 pancreatic lipase deficiency 10.3
4 sulfonamide allergy 10.3 GFPT2 GFPT1
5 angular cheilitis 10.3 GFPT2 GFPT1
6 cystic fibrosis 10.3
7 pancreatic agenesis 1 10.3 SCT PNLIP
8 lipodystrophy, familial partial, type 2 10.2 GFPT2 GFPT1
9 recurrent acute pancreatitis 10.2 SCT PRSS1
10 biliary dyskinesia 10.2 SCT CCK
11 duodenogastric reflux 10.2 SCT CCK
12 pancreatic cholera 10.2 SCT CCK
13 duodenal gastrinoma 10.2 SCT CCK
14 fungal esophagitis 10.2 ATP4A ATP12A
15 diclofenac allergy 10.2 ATP4A ATP12A
16 neonatal candidiasis 10.2 ATP4A ATP12A
17 squamous papillomatosis 10.2 ATP4A ATP12A
18 photoallergic dermatitis 10.2 ATP4A ATP12A
19 aspiration pneumonitis 10.2 ATP4A ATP12A
20 toxic megacolon 10.2 ATP4A ATP12A
21 gastric antral vascular ectasia 10.2 ATP4A ATP12A
22 acute laryngitis 10.2 ATP4A ATP12A
23 laryngitis 10.2 ATP4A ATP12A
24 esophageal candidiasis 10.2 ATP4A ATP12A
25 duodenitis 10.2 ATP4A ATP12A
26 active peptic ulcer disease 10.2 ATP4A ATP12A
27 rumination disorder 10.2 ATP4A ATP12A
28 dyskinesia of esophagus 10.2 ATP4A ATP12A
29 peptic esophagitis 10.2 ATP4A ATP12A
30 capillary disease 10.2 ATP4A ATP12A
31 ischemic neuropathy 10.2 ATP4A ATP12A
32 bladder calculus 10.2 ATP4A ATP12A
33 congenital disorder of deglycosylation 10.2 ATP4A ATP12A
34 hernia, hiatus 10.2 ATP4A ATP12A
35 postsurgical hypothyroidism 10.2 ATP4A ATP12A
36 esophageal atresia/tracheoesophageal fistula 10.2 ATP4A ATP12A
37 lymphocytic colitis 10.2 ATP4A ATP12A
38 clostridium difficile colitis 10.2 ATP4A ATP12A
39 diarrhea 1, secretory chloride, congenital 10.2 ATP4A ATP12A
40 laryngeal tuberculosis 10.1 ATP4A ATP12A
41 microscopic colitis 10.1 ATP4A ATP12A
42 tropical calcific pancreatitis 10.1 PRSS1 CTSB
43 chronic intestinal vascular insufficiency 10.1 ATP4A ATP12A
44 esophagus adenocarcinoma 10.1 ATP4A ATP12A
45 eosinophilic gastritis 10.1 ATP4A ATP12A
46 chronic laryngitis 10.1 ATP4A ATP12A
47 exocrine pancreatic insufficiency 10.1 SCT PNLIP CCK
48 diphyllobothriasis 10.1 SCT CBLIF
49 superior mesenteric artery syndrome 10.1 ATP4A ATP12A
50 alcoholic pancreatitis 10.1 SCT PRSS1 CCK

Comorbidity relations with Pancreatic Steatorrhea via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pancreatic Steatorrhea:



Diseases related to Pancreatic Steatorrhea

Symptoms & Phenotypes for Pancreatic Steatorrhea

Drugs & Therapeutics for Pancreatic Steatorrhea

Search Clinical Trials , NIH Clinical Center for Pancreatic Steatorrhea

Genetic Tests for Pancreatic Steatorrhea

Anatomical Context for Pancreatic Steatorrhea

MalaCards organs/tissues related to Pancreatic Steatorrhea:

41
Testes, Pancreas, Skin

Publications for Pancreatic Steatorrhea

Articles related to Pancreatic Steatorrhea:

(show all 28)
# Title Authors Year
1
Are minimicrosphere pancrelipase capsules effective enough for the treatment of pancreatic steatorrhea? ( 11374718 )
2001
2
Determination of fecal fat concentration by near infrared spectrometry for the screening of pancreatic steatorrhea. ( 9520087 )
1998
3
Can pancreatic steatorrhea be diagnosed without chemical analysis? ( 9387033 )
1997
4
Pancreatic steatorrhea, malabsorption, and nutrition biochemistry: a comparison of Japanese, European, and American patients with chronic pancreatitis. ( 9163777 )
1997
5
New enteric-coated high-lipase pancreatic extract in the treatment of pancreatic steatorrhea. ( 8113582 )
1994
6
Increased intragastric acid-resistant lipase activity and lipolysis in pancreatic steatorrhoea due to cystic fibrosis. ( 1594551 )
1992
7
Therapeutic potential and clinical efficacy of acid-resistant fungal lipase in the treatment of pancreatic steatorrhoea due to cystic fibrosis. ( 1594552 )
1992
8
Determination of faecal chymotrypsin concentration and 72-hour faecal chymotrypsin output in the detection of pancreatic steatorrhoea. ( 1775936 )
1991
9
Fecal fat concentrations and pancreatic steatorrhea. ( 3337054 )
1988
10
Pancreatic steatorrhea and pulmonary tuberculosis. ( 3361162 )
1988
11
Detection of pancreatic steatorrhea by oral pancreatic function tests. ( 3262493 )
1988
12
Serum cathodic trypsin-like immunoreactivity, pancreatic lipase, and pancreatic isoamylase as diagnostic tests of chronic pancreatitis or pancreatic steatorrhea. ( 3291084 )
1988
13
Raised fecal fat concentration is not a valid indicator of pancreatic steatorrhea. ( 3646827 )
1987
14
Pancreatic steatorrhea: action of a total lyophilized pancreas preparation: an "in vitro" and "in vivo" study. ( 3435264 )
1986
15
Effect of cimetidine in pancreatic steatorrhoea. ( 18668874 )
1986
16
Effect of intrajejunal acidity on aqueous phase bile acid and lipid concentrations in pancreatic steatorrhoea due to cystic fibrosis. ( 6714794 )
1984
17
Decrease in pancreatic steatorrhoea by positioned-release enzyme capsules. ( 6814569 )
1982
18
Pancreatic Society of Great Britain and Ireland: Annual Meeting, 1980: Role of pH-dependent bile acid precipitation in fat maldigestion due to pancreatic steatorrhoea. Preliminary communication. ( 19310778 )
1982
19
Double-blind cross-over trial of an enzyme preparation in pancreatic steatorrhoea. ( 6912244 )
1981
20
Small bowel structure and function in pancreatic steatorrhea. ( 1082072 )
1975
21
Increase in urinary indican excretion in pancreatic steatorrhoea following replacement therapy. ( 1153945 )
1975
22
Pancreatic scanning in the assessment of pancreatic function: experiences with 14 cases of pancreatic steatorrhoea. ( 4568024 )
1972
23
Pancreatic steatorrhea. ( 5681601 )
1968
24
A case of pancreatic steatorrhoea. ( 6043129 )
1967
25
Maintenance therapy of pancreatic steatorrhoea with concentrated pancreatic extract. ( 5323324 )
1965
26
PANCREATIC REPLACEMENT THERAPY IN THE TREATMENT OF PANCREATIC STEATORRHOEA. ( 14058262 )
1963
27
Thyroxine metabolism in untreated and treated pancreatic steatorrhea. ( 13907777 )
1962
28
Chronic relapsing pancreatitis apparently initiated by trauma: report of a case with eventual development of pancreatic calcification, diabetes mellitus, pancreatic steatorrhea, and duodenal ulcer with hematemesis and melena. ( 13826234 )
1959

Variations for Pancreatic Steatorrhea

Expression for Pancreatic Steatorrhea

Search GEO for disease gene expression data for Pancreatic Steatorrhea.

Pathways for Pancreatic Steatorrhea

Pathways related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.11 CELA3B PNLIP PRSS1
2 10.87 GFPT1 GFPT2
3 10.64 CBLIF PNLIP
4 10.48 CBLIF PRSS1
5 9.64 CBLIF CCK SCT

GO Terms for Pancreatic Steatorrhea

Cellular components related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CBLIF CCK CELA1 CTSB GHRL PNLIP
2 extracellular space GO:0005615 9.36 ATP4A CBLIF CCK CELA1 CELA3B CTSB

Biological processes related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.58 ATP12A ATP4A
2 protein N-linked glycosylation GO:0006487 9.57 GFPT1 GFPT2
3 potassium ion import GO:0010107 9.56 ATP12A ATP4A
4 digestion GO:0007586 9.55 CCK PRSS1
5 ATP hydrolysis coupled proton transport GO:0015991 9.54 ATP12A ATP4A
6 decidualization GO:0046697 9.52 CTSB GHRL
7 glutamine metabolic process GO:0006541 9.51 GFPT1 GFPT2
8 cobalamin metabolic process GO:0009235 9.49 CBLIF PRSS1
9 cellular sodium ion homeostasis GO:0006883 9.48 ATP12A ATP4A
10 energy reserve metabolic process GO:0006112 9.46 GFPT1 GFPT2
11 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.43 ATP12A ATP4A
12 cellular potassium ion homeostasis GO:0030007 9.4 ATP12A ATP4A
13 sodium ion export across plasma membrane GO:0036376 9.37 ATP12A ATP4A
14 UDP-N-acetylglucosamine biosynthetic process GO:0006048 9.32 GFPT1 GFPT2
15 fructose 6-phosphate metabolic process GO:0006002 9.26 GFPT1 GFPT2
16 UDP-N-acetylglucosamine metabolic process GO:0006047 9.16 GFPT1 GFPT2
17 carbohydrate derivative metabolic process GO:1901135 8.96 GFPT1 GFPT2
18 carbohydrate derivative biosynthetic process GO:1901137 8.62 GFPT1 GFPT2

Molecular functions related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.87 ATP12A ATP4A CELA1 CELA3B CTSB PNLIP
2 peptidase activity GO:0008233 9.78 CELA1 CELA3B CTSB PRSS1
3 serine-type peptidase activity GO:0008236 9.61 CELA1 CELA3B PRSS1
4 hormone activity GO:0005179 9.58 CCK GHRL SCT
5 serine-type endopeptidase activity GO:0004252 9.56 CELA1 CELA3B CTSB PRSS1
6 transaminase activity GO:0008483 9.46 GFPT1 GFPT2
7 sodium:potassium-exchanging ATPase activity GO:0005391 9.37 ATP12A ATP4A
8 carbohydrate derivative binding GO:0097367 9.16 GFPT1 GFPT2
9 potassium:proton exchanging ATPase activity GO:0008900 8.96 ATP12A ATP4A
10 glutamine-fructose-6-phosphate transaminase (isomerizing) activity GO:0004360 8.62 GFPT1 GFPT2

Sources for Pancreatic Steatorrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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