MCID: PNC028
MIFTS: 30

Pancreatic Steatorrhea

Categories: Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Pancreatic Steatorrhea

MalaCards integrated aliases for Pancreatic Steatorrhea:

Name: Pancreatic Steatorrhea 12 15 73
Pancreatic Steatorrhoea 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10610
ICD10 33 K90.3
ICD9CM 35 579.4
UMLS 73 C0152166

Summaries for Pancreatic Steatorrhea

MalaCards based summary : Pancreatic Steatorrhea, also known as pancreatic steatorrhoea, is related to steatorrhea and duodenitis. An important gene associated with Pancreatic Steatorrhea is GFPT2 (Glutamine-Fructose-6-Phosphate Transaminase 2), and among its related pathways/superpathways are Pancreatic secretion and Alanine, aspartate and glutamate metabolism. Affiliated tissues include testes and pancreas.

Related Diseases for Pancreatic Steatorrhea

Diseases related to Pancreatic Steatorrhea via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
# Related Disease Score Top Affiliating Genes
1 steatorrhea 30.7 CCK CELA1 PNLIP SCT
2 duodenitis 30.3 ATP12A ATP4A
3 pancreatitis 29.8 CCK CTSB PNLIP PRSS1 SCT
4 angular cheilitis 10.9 GFPT1 GFPT2
5 lipodystrophy, familial partial, type 2 10.9 GFPT1 GFPT2
6 pancreatic agenesis 1 10.8 PNLIP SCT
7 biliary dyskinesia 10.7 CCK SCT
8 recurrent acute pancreatitis 10.7 PRSS1 SCT
9 duodenogastric reflux 10.6 CCK SCT
10 pancreatic cholera 10.6 CCK SCT
11 duodenal gastrinoma 10.6 CCK SCT
12 fungal esophagitis 10.5 ATP12A ATP4A
13 bladder calculus 10.5 ATP12A ATP4A
14 gastrointestinal neuroendocrine benign tumor 10.5 ATP12A ATP4A
15 neonatal candidiasis 10.5 ATP12A ATP4A
16 photoallergic dermatitis 10.5 ATP12A ATP4A
17 squamous papillomatosis 10.5 ATP12A ATP4A
18 acute laryngitis 10.5 ATP12A ATP4A
19 gastric neuroendocrine neoplasm 10.5 ATP12A ATP4A
20 toxic megacolon 10.5 ATP12A ATP4A
21 aspiration pneumonitis 10.5 ATP12A ATP4A
22 postsurgical hypothyroidism 10.4 ATP12A ATP4A
23 exocrine pancreatic insufficiency 10.4 CCK PNLIP SCT
24 gastric antral vascular ectasia 10.4 ATP12A ATP4A
25 diphyllobothriasis 10.4 GIF SCT
26 esophageal candidiasis 10.4 ATP12A ATP4A
27 rumination disorder 10.4 ATP12A ATP4A
28 active peptic ulcer disease 10.4 ATP12A ATP4A
29 laryngeal disease 10.4 ATP12A ATP4A
30 ischemic neuropathy 10.4 ATP12A ATP4A
31 capillary disease 10.4 ATP12A ATP4A
32 peptic esophagitis 10.4 ATP12A ATP4A
33 dyskinesia of esophagus 10.4 ATP12A ATP4A
34 alcoholic pancreatitis 10.4 CCK PRSS1 SCT
35 hernia, hiatus 10.4 ATP12A ATP4A
36 congenital disorder of deglycosylation 10.4 ATP12A ATP4A
37 esophageal atresia/tracheoesophageal fistula 10.4 ATP12A ATP4A
38 laryngitis 10.4 ATP12A ATP4A
39 laryngeal tuberculosis 10.4 ATP12A ATP4A
40 lymphocytic colitis 10.4 ATP12A ATP4A
41 tropical calcific pancreatitis 10.4 CTSB PRSS1
42 clostridium difficile colitis 10.4 ATP12A ATP4A
43 lower urinary tract calculus 10.4 ATP12A ATP4A
44 diarrhea 1, secretory chloride, congenital 10.4 ATP12A ATP4A
45 chronic laryngitis 10.3 ATP12A ATP4A
46 chronic intestinal vascular insufficiency 10.3 ATP12A ATP4A
47 eosinophilic gastritis 10.3 ATP12A ATP4A
48 polyposis, skin pigmentation, alopecia, and fingernail changes 10.3 ATP12A ATP4A
49 esophageal varix 10.3 ATP12A ATP4A
50 esophagus adenocarcinoma 10.3 ATP12A ATP4A

Comorbidity relations with Pancreatic Steatorrhea via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pancreatic Steatorrhea:



Diseases related to Pancreatic Steatorrhea

Symptoms & Phenotypes for Pancreatic Steatorrhea

Drugs & Therapeutics for Pancreatic Steatorrhea

Search Clinical Trials , NIH Clinical Center for Pancreatic Steatorrhea

Genetic Tests for Pancreatic Steatorrhea

Anatomical Context for Pancreatic Steatorrhea

MalaCards organs/tissues related to Pancreatic Steatorrhea:

41
Testes, Pancreas

Publications for Pancreatic Steatorrhea

Articles related to Pancreatic Steatorrhea:

(show all 15)
# Title Authors Year
1
Are minimicrosphere pancrelipase capsules effective enough for the treatment of pancreatic steatorrhea? ( 11374718 )
2001
2
Determination of fecal fat concentration by near infrared spectrometry for the screening of pancreatic steatorrhea. ( 9520087 )
1998
3
Can pancreatic steatorrhea be diagnosed without chemical analysis? ( 9387033 )
1997
4
Pancreatic steatorrhea, malabsorption, and nutrition biochemistry: a comparison of Japanese, European, and American patients with chronic pancreatitis. ( 9163777 )
1997
5
New enteric-coated high-lipase pancreatic extract in the treatment of pancreatic steatorrhea. ( 8113582 )
1994
6
Fecal fat concentrations and pancreatic steatorrhea. ( 3337054 )
1988
7
Pancreatic steatorrhea and pulmonary tuberculosis. ( 3361162 )
1988
8
Detection of pancreatic steatorrhea by oral pancreatic function tests. ( 3262493 )
1988
9
Serum cathodic trypsin-like immunoreactivity, pancreatic lipase, and pancreatic isoamylase as diagnostic tests of chronic pancreatitis or pancreatic steatorrhea. ( 3291084 )
1988
10
Raised fecal fat concentration is not a valid indicator of pancreatic steatorrhea. ( 3646827 )
1987
11
Pancreatic steatorrhea: action of a total lyophilized pancreas preparation: an "in vitro" and "in vivo" study. ( 3435264 )
1986
12
Small bowel structure and function in pancreatic steatorrhea. ( 1082072 )
1975
13
Pancreatic steatorrhea. ( 5681601 )
1968
14
Thyroxine metabolism in untreated and treated pancreatic steatorrhea. ( 13907777 )
1962
15
Chronic relapsing pancreatitis apparently initiated by trauma: report of a case with eventual development of pancreatic calcification, diabetes mellitus, pancreatic steatorrhea, and duodenal ulcer with hematemesis and melena. ( 13826234 )
1959

Variations for Pancreatic Steatorrhea

Expression for Pancreatic Steatorrhea

Search GEO for disease gene expression data for Pancreatic Steatorrhea.

Pathways for Pancreatic Steatorrhea

Pathways related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.11 CELA3B PNLIP PRSS1
2 10.87 GFPT1 GFPT2
3 10.64 GIF PNLIP
4 10.48 GIF PRSS1
5 9.64 CCK GIF SCT

GO Terms for Pancreatic Steatorrhea

Cellular components related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CCK CELA1 CTSB GHRL GIF PNLIP
2 extracellular space GO:0005615 9.36 ATP4A CCK CELA1 CELA3B CTSB GHRL

Biological processes related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 potassium ion import GO:0010107 9.55 ATP12A ATP4A
2 ATP hydrolysis coupled proton transport GO:0015991 9.54 ATP12A ATP4A
3 decidualization GO:0046697 9.52 CTSB GHRL
4 glutamine metabolic process GO:0006541 9.51 GFPT1 GFPT2
5 cobalamin metabolic process GO:0009235 9.49 GIF PRSS1
6 cellular sodium ion homeostasis GO:0006883 9.48 ATP12A ATP4A
7 cellular potassium ion homeostasis GO:0030007 9.46 ATP12A ATP4A
8 energy reserve metabolic process GO:0006112 9.43 GFPT1 GFPT2
9 sodium ion export across plasma membrane GO:0036376 9.4 ATP12A ATP4A
10 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.37 ATP12A ATP4A
11 UDP-N-acetylglucosamine biosynthetic process GO:0006048 9.32 GFPT1 GFPT2
12 fructose 6-phosphate metabolic process GO:0006002 9.26 GFPT1 GFPT2
13 UDP-N-acetylglucosamine metabolic process GO:0006047 9.16 GFPT1 GFPT2
14 carbohydrate derivative metabolic process GO:1901135 8.96 GFPT1 GFPT2
15 carbohydrate derivative biosynthetic process GO:1901137 8.62 GFPT1 GFPT2

Molecular functions related to Pancreatic Steatorrhea according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.87 ATP12A ATP4A CELA1 CELA3B CTSB PNLIP
2 peptidase activity GO:0008233 9.78 CELA1 CELA3B CTSB PRSS1
3 serine-type peptidase activity GO:0008236 9.63 CELA1 CELA3B PRSS1
4 hormone activity GO:0005179 9.58 CCK GHRL SCT
5 serine-type endopeptidase activity GO:0004252 9.56 CELA1 CELA3B CTSB PRSS1
6 transaminase activity GO:0008483 9.43 GFPT1 GFPT2
7 sodium:potassium-exchanging ATPase activity GO:0005391 9.37 ATP12A ATP4A
8 potassium:proton exchanging ATPase activity GO:0008900 9.16 ATP12A ATP4A
9 carbohydrate derivative binding GO:0097367 8.96 GFPT1 GFPT2
10 glutamine-fructose-6-phosphate transaminase (isomerizing) activity GO:0004360 8.62 GFPT1 GFPT2

Sources for Pancreatic Steatorrhea

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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