MCID: PNC019
MIFTS: 34

Pancreatoblastoma

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Pancreatoblastoma

MalaCards integrated aliases for Pancreatoblastoma:

Name: Pancreatoblastoma 12 75 53 59 44 15 17 72

Characteristics:

Orphanet epidemiological data:

59
pancreatoblastoma
Inheritance: Not applicable; Prevalence: <1/1000000 (Europe),<1/1000000 (Worldwide); Age of onset: Adult,Childhood; Age of death: adult,early childhood,late childhood;

Classifications:



External Ids:

Disease Ontology 12 DOID:6823
MeSH 44 C537162
NCIt 50 C4265
SNOMED-CT 68 53618008
MESH via Orphanet 45 C537162
ICD10 via Orphanet 34 C25.1
UMLS via Orphanet 73 C0334489
Orphanet 59 ORPHA677
UMLS 72 C0334489

Summaries for Pancreatoblastoma

MalaCards based summary : Pancreatoblastoma is related to acinar cell carcinoma and pancreatic acinar cell adenocarcinoma, and has symptoms including abdominal pain, pruritus and icterus. An important gene associated with Pancreatoblastoma is AFP (Alpha Fetoprotein). Affiliated tissues include pancreas, liver and lymph node, and related phenotypes are vomiting and abdominal pain

Wikipedia : 75 Pancreatoblastoma is a rare type of pancreatic cancer.It occurs mainly in childhood and has a relatively... more...

Related Diseases for Pancreatoblastoma

Diseases related to Pancreatoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 acinar cell carcinoma 30.9 SERPINA1 CHGA AFP
2 pancreatic acinar cell adenocarcinoma 30.7 CHGA AFP
3 ectopic cushing syndrome 30.3 SYP SST
4 rare tumor 10.6
5 mucinous cystadenofibroma 10.6 SERPINA1 AFP
6 cystadenofibroma 10.6 SERPINA1 AFP
7 polyembryoma 10.6 SERPINA1 AFP
8 teratoma 10.5 SYP AFP
9 malignant sertoli cell tumor 10.5 SYP AFP
10 rare tumor of pancreas 10.5
11 beckwith-wiedemann syndrome 10.5
12 endometrial small cell carcinoma 10.5 SYP AFP
13 malignant teratoma 10.5 SYP AFP
14 adult teratoma 10.5 CHGA AFP
15 ovarian endodermal sinus tumor 10.5 SERPINA1 AFP
16 mediastinal cancer 10.5 SYP AFP
17 sclerosing hepatic carcinoma 10.5 CHGA AFP
18 male reproductive organ benign neoplasm 10.5 SYP AFP
19 seminal vesicle tumor 10.5 SYP AFP
20 ovarian primitive germ cell tumor 10.5 SERPINA1 AFP
21 liver sarcoma 10.4 CHGA AFP
22 pineoblastoma 10.4 SYP AFP
23 ureter small cell carcinoma 10.4 SYP CHGA
24 small cell carcinoma 10.4 SYP CHGA
25 pancreatic cancer 10.4
26 esophageal neuroendocrine tumor 10.4 SYP CHGA
27 urinary bladder small cell neuroendocrine carcinoma 10.4 SYP CHGA
28 embryoma 10.4 KRT14 AFP
29 ovarian large-cell neuroendocrine carcinoma 10.4 SYP CHGA
30 auditory system cancer 10.4 SYP CHGA
31 primary hepatic neuroendocrine carcinoma 10.4 SYP CHGA
32 cellular ependymoma 10.4 SYP CHGA
33 peritoneal serous adenocarcinoma 10.4 SYP CHGA
34 small cell carcinoma of the bladder 10.4 SYP CHGA
35 chordoid meningioma 10.4 SYP CHGA
36 mixed cell type cancer 10.4 SYP AFP
37 atypical follicular adenoma 10.4 SYP CHGA
38 gallbladder small cell carcinoma 10.4 SYP CHGA
39 pulmonary large cell neuroendocrine carcinoma 10.4 SYP CHGA
40 large cell neuroendocrine carcinoma 10.4 SYP CHGA
41 olfactory groove meningioma 10.4 SYP CHGA
42 cauda equina neoplasm 10.4 SYP CHGA
43 conventional angiosarcoma 10.4 SYP CHGA
44 pancreatic serous cystadenoma 10.4 SYP CHGA
45 cystadenoma 10.4 SYP CHGA
46 olfactory nerve neoplasm 10.4 SYP CHGA
47 nodular ganglioneuroblastoma 10.4 SYP CHGA
48 autonomic nervous system benign neoplasm 10.4 SYP CHGA
49 pineocytoma 10.4 SYP CHGA
50 pulmonary sclerosing hemangioma 10.4 SYP CHGA

Graphical network of the top 20 diseases related to Pancreatoblastoma:



Diseases related to Pancreatoblastoma

Symptoms & Phenotypes for Pancreatoblastoma

Human phenotypes related to Pancreatoblastoma:

59 32 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 vomiting 59 32 frequent (33%) Frequent (79-30%) HP:0002013
2 abdominal pain 59 32 frequent (33%) Frequent (79-30%) HP:0002027
3 weight loss 59 32 frequent (33%) Frequent (79-30%) HP:0001824
4 diarrhea 59 32 frequent (33%) Frequent (79-30%) HP:0002014
5 abdominal distention 59 32 frequent (33%) Frequent (79-30%) HP:0003270
6 pancreatic calcification 59 32 frequent (33%) Frequent (79-30%) HP:0005213
7 elevated maternal serum alpha-fetoprotein 59 32 frequent (33%) Frequent (79-30%) HP:0005984
8 jaundice 59 32 occasional (7.5%) Occasional (29-5%) HP:0000952
9 abnormality of the lymph nodes 59 32 occasional (7.5%) Occasional (29-5%) HP:0002733

UMLS symptoms related to Pancreatoblastoma:


abdominal pain, pruritus, icterus

Drugs & Therapeutics for Pancreatoblastoma

Search Clinical Trials , NIH Clinical Center for Pancreatoblastoma

Cochrane evidence based reviews: pancreatoblastoma

Genetic Tests for Pancreatoblastoma

Anatomical Context for Pancreatoblastoma

MalaCards organs/tissues related to Pancreatoblastoma:

41
Pancreas, Liver, Lymph Node, Brain

Publications for Pancreatoblastoma

Articles related to Pancreatoblastoma:

(show top 50) (show all 243)
# Title Authors PMID Year
1
Mosaic paternal haploidy in a patient with pancreatoblastoma and Beckwith-Wiedemann spectrum. 38
31231953 2019
2
The Italian Rare Pancreatic Exocrine Cancer Initiative. 38
30967031 2019
3
Diagnosis and treatment of pancreatoblastoma in children: a retrospective study in a single pediatric center. 38
31338582 2019
4
Adult Pancreatoblastoma With Liver Metastasis Diagnosed by 18F-FDG PET/CT and 2 Years' Postoperative Follow-up. 38
31274558 2019
5
Defining and listing very rare cancers of paediatric age: consensus of the Joint Action on Rare Cancers in cooperation with the European Cooperative Study Group for Pediatric Rare Tumors. 38
30785015 2019
6
Tissue variations of mosaic genome-wide paternal uniparental disomy and phenotype of multi-syndromal congenital hyperinsulinism. 38
30797057 2019
7
FDG-PET CT in the evaluation of primary and secondary pancreatic malignancies. 38
29750397 2018
8
Pancreatoblastoma: an Atypical Presentation and a Literature Review. 38
28194556 2018
9
Adult pancreatoblastoma: A case report and clinicopathological review of the literature. 38
29753278 2018
10
Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract: 2018 Update. 38
29776636 2018
11
Pancreatoblastoma: an unusual diagnosis in an adult patient. 38
29285688 2018
12
A population-based analysis of a rare oncologic entity: Malignant pancreatic tumors in children. 38
28693851 2018
13
Pancreatectomies for pancreatic neoplasms in pediatric and adolescent age: A single institution experience. 38
29277262 2018
14
Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. 38
29535845 2018
15
Liver transplant for metastatic pancreatoblastoma: 7-year event-free survival after chemotherapy, pancreatectomy, complete hepatectomy, and liver transplant. 38
29235221 2018
16
Integrated Molecular Characterization of the Lethal Pediatric Cancer Pancreatoblastoma. 38
29233928 2018
17
Pancreatoblastoma in a paediatric patient: anatomo-pathological aspects of a case with multiple hepatic metastases. 38
30174723 2018
18
Pathologic classification of "pancreatic cancers": current concepts and challenges. 38
29307199 2017
19
Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors. 38
29259370 2017
20
[Clinicopathologic characteristics of pancreatoblastoma]. 38
29224282 2017
21
Pancreatoblastoma With Metastatic Retroperitoneal Lymph Node and PET/CT. 38
28872552 2017
22
Genetic basis of a common tumor origin in the development of pancreatic mixed acinar-neuroendocrine-ductal carcinoma: A case report. 38
29085438 2017
23
Complete Resection of Pancreatoblastoma With Portal Vein Obstruction After High-dose Chemotherapy: A Case Report. 38
28538503 2017
24
Pancreaticoduodenectomy for pediatric and adolescent pancreatic malignancy: A single-center retrospective analysis. 38
27894759 2017
25
Pancreatoblastoma Masquerading as a Retroperitoneal Germ Cell Tumor. 38
28082787 2017
26
Pancreatoblastoma, a Rare Childhood Tumor: A Case Report. 38
25110242 2017
27
Fine needle aspiration cytology diagnosis of a pancreatoblastoma in an infant: case report with a summary of prior published cases. 38
27038102 2016
28
Acinar neoplasms of the pancreas-A summary of 25 years of research. 38
27320062 2016
29
Pancreatic surgery for tumors in children and adolescents. 38
27364750 2016
30
Adult pancreatoblastoma - Case report and review of literature. 38
27761191 2016
31
Surgical and molecular pathology of pancreatic neoplasms. 38
27267993 2016
32
Pancreatoblastoma masquerading as hepatoblastoma: A diagnostic dilemma. 38
27046982 2016
33
Pancreatoblastoma an Unusual Occurrence of a Tumour in Paediatric Age Group: A Case Report. 38
27134883 2016
34
Multi-Visceral Transplantation in a 21-Year-Old Man with Prior Pancreatoblastoma. 38
27721967 2016
35
[Report of 14 cases with pancreatoblastoma]. 38
26791924 2016
36
Ectopic Cushing syndrome secondary to recurrent pancreatoblastoma in a child: Lessons learnt. 38
26881602 2015
37
Pancreatic tumours in children: diagnosis, treatment and outcome. 38
26174862 2015
38
Clinicopathological review of pancreatoblastoma in adults. 38
26312218 2015
39
Response of Relapsed Pancreatoblastoma to a Combination of Vinorelbine and Oral Cyclophosphamide. 38
26056794 2015
40
Uncommon presentations of common pancreatic neoplasms: a pictorial essay. 38
25772002 2015
41
Successful emergency combined therapy with partial splenic arterial embolization and endoscopic injection therapy against a bleeding duodenal varix in a child. 38
25851961 2015
42
Adult pancreatoblastoma: A case report and review of the literature. 38
26137059 2015
43
ACTH-secreting pancreatic neoplasms associated with Cushing syndrome: clinicopathologic study of 11 cases and review of the literature. 38
25353285 2015
44
[Other pancreatic neoplasms (pancreatoblastoma, hepatoid carcinoma and medullary carcinoma)]. 38
25857052 2015
45
Multifocal pancreatoblastoma with pseudocyst in a 2-year-old boy. 38
26591960 2015
46
A need for cautious interpretation of elevated serum germ cell tumor markers in children. Review and own experiences. 38
26329804 2015
47
Pancreatoblastoma in an adult. 38
25673604 2015
48
Pathology and genetics of pancreatic neoplasms with acinar differentiation. 38
25441307 2014
49
Imaging features of primary malignant pancreatic tumors in children. 38
25148173 2014
50
Imaging of pediatric pancreatic neoplasms with radiologic-histopathologic correlation. 38
24848833 2014

Variations for Pancreatoblastoma

Expression for Pancreatoblastoma

Search GEO for disease gene expression data for Pancreatoblastoma.

Pathways for Pancreatoblastoma

GO Terms for Pancreatoblastoma

Cellular components related to Pancreatoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.35 AFP CHGA KRT10 SERPINA1 SST
2 extracellular region GO:0005576 9.1 SST SERPINA1 NTS KRT10 CHGA AFP

Sources for Pancreatoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....