Aliases & Classifications for Pancytopenia

MalaCards integrated aliases for Pancytopenia:

Name: Pancytopenia 12 29 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:12450
ICD10 33 D61.81
ICD9CM 35 284.1
MeSH 44 D010198
UMLS 73 C0030312

Summaries for Pancytopenia

Disease Ontology : 12 An anemia that is characterized by a reduction in the number of red blood cells, white blood cells, and platelets.

MalaCards based summary : Pancytopenia is related to fanconi anemia, complementation group a and dyskeratosis congenita. An important gene associated with Pancytopenia is SAMD9L (Sterile Alpha Motif Domain Containing 9 Like), and among its related pathways/superpathways are PI3K-Akt signaling pathway and JAK-STAT signaling pathway (KEGG). The drugs Benzocaine and tannic acid have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and liver, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 76 Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood... more...

Related Diseases for Pancytopenia

Diseases related to Pancytopenia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 379)
# Related Disease Score Top Affiliating Genes
1 fanconi anemia, complementation group a 32.5 DHFR DKC1 IL3 LIG4 THPO
2 dyskeratosis congenita 32.2 CSF2 CSF3 DKC1 LIG4 TERT
3 amegakaryocytic thrombocytopenia, congenital 31.9 IL3 MPL THPO
4 diamond-blackfan anemia 30.7 CSF2 EPO IL3 MPL THPO
5 aplastic anemia 30.3 CD55 CSF1 CSF2 CSF3 DKC1 EPO
6 hypersplenism 30.0 CSF2 EPO THPO
7 thrombocytopenia 29.9 CSF3 MPL THPO
8 neutropenia 29.6 CSF2 CSF3 IL3 TPMT
9 myeloma, multiple 29.6 CSF2 CSF3 EPO LIG4
10 myelofibrosis 29.6 CSF3 EPO IL3 MPL THPO
11 malaria 29.4 CD55 CSF2 CSF3 DHFR EPO TCN2
12 granulocytopenia 29.2 CSF2 CSF3 IL3
13 cyclic neutropenia 29.2 CSF2 CSF3 IL3
14 deficiency anemia 29.2 CSF3 EPO IL3 THPO
15 refractory anemia 29.2 EPO IL3 MPL
16 severe congenital neutropenia 29.2 CSF2 CSF3 IL3
17 leukemia, acute myeloid 28.9 CSF2 CSF3 IL3 MPL SAMD9L TERT
18 polycythemia 28.9 EPO IL3 MPL THPO
19 polycythemia vera 28.9 EPO IL3 MPL THPO
20 myelodysplastic syndrome 28.7 CD55 CSF1 CSF2 CSF3 EPO IL3
21 thrombocytosis 28.7 CSF2 EPO IL3 MPL THPO
22 leukemia, chronic myeloid 28.5 CSF2 CSF3 EPO IL3 MPL THPO
23 ataxia-pancytopenia syndrome 12.5
24 samd9l-related ataxia-pancytopenia syndrome 12.2
25 pancytopenia and occlusive vascular disease 12.0
26 dyskeratosis congenita, x-linked 11.5
27 sackey sakati aur syndrome 11.5
28 fanconi anemia, complementation group c 11.3
29 fanconi anemia, complementation group d2 11.3
30 fanconi anemia, complementation group b 11.3
31 hemophagocytic lymphohistiocytosis 11.2
32 fanconi-like syndrome 11.2
33 radioulnar synostosis with amegakaryocytic thrombocytopenia 2 11.0
34 bone marrow failure syndrome 3 11.0
35 cerebroretinal microangiopathy with calcifications and cysts 2 11.0
36 bone marrow failure syndrome 2 11.0
37 immunodeficiency, common variable, 13 11.0
38 evans' syndrome 11.0
39 osteopetrosis, autosomal dominant 2 10.9
40 gaucher disease, type iii 10.9
41 methylmalonyl-coa epimerase deficiency 10.9
42 osteopetrosis, autosomal recessive 1 10.9
43 osteopetrosis, autosomal recessive 2 10.9
44 osteopetrosis, autosomal recessive 5 10.9
45 osteopetrosis, autosomal recessive 3 10.9
46 transcobalamin ii deficiency 10.9
47 lymphoproliferative syndrome, x-linked, 2 10.9
48 lymphoproliferative syndrome, x-linked, 1 10.9
49 hemophagocytic lymphohistiocytosis, familial, 2 10.9
50 radioulnar synostosis with amegakaryocytic thrombocytopenia 1 10.9

Graphical network of the top 20 diseases related to Pancytopenia:



Diseases related to Pancytopenia

Symptoms & Phenotypes for Pancytopenia

MGI Mouse Phenotypes related to Pancytopenia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.21 CD55 CSF1 CSF2 CSF3 DHFR DKC1
2 homeostasis/metabolism MP:0005376 10.13 CSF1 CSF2 DHFR DKC1 EPO LIG4
3 immune system MP:0005387 10.07 CD55 CSF1 CSF2 CSF3 DHFR DKC1
4 integument MP:0010771 9.7 CSF1 CSF2 CSF3 DHFR DKC1 EPO
5 mortality/aging MP:0010768 9.7 CSF1 CSF2 DHFR DKC1 EPO LIG4
6 neoplasm MP:0002006 9.1 CSF2 DKC1 LIG4 MGMT SAMD9L TERT

Drugs & Therapeutics for Pancytopenia

Drugs for Pancytopenia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 226)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Phase 2,Not Applicable 94-09-7, 1994-09-7 2337
2 tannic acid Approved Phase 4,Phase 2,Not Applicable
3
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 135968-09-1
4
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 1 53-03-2 5865
5
Busulfan Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable 55-98-1 2478
6
Fludarabine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 75607-67-9, 21679-14-1 30751
7
Oprelvekin Approved, Investigational Phase 4 145941-26-0
8
Peginterferon alfa-2a Approved, Investigational Phase 4 198153-51-4 5360545
9
Ribavirin Approved Phase 4 36791-04-5 37542
10
Pantoprazole Approved Phase 4 102625-70-7 4679
11
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
12
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
13
Ticlopidine Approved Phase 4 55142-85-3 5472
14
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
15
Haloperidol Approved Phase 4 52-86-8 3559
16
Treosulfan Investigational Phase 4,Phase 2 299-75-2 9296
17 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
18 Cyclosporins Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19 Antiviral Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
20 Immunologic Factors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
21 Antimetabolites Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
22 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
23 Antilymphocyte Serum Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Protective Agents Phase 4,Phase 2,Phase 1
25 Antineoplastic Agents, Alkylating Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
26 Alkylating Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1
27 decanoic acid Phase 4,Phase 1,Phase 2
28 Interferon-alpha Phase 4
29 interferons Phase 4
30 Anti-Ulcer Agents Phase 4
31 Antacids Phase 4
32 Gastrointestinal Agents Phase 4,Phase 2,Phase 1,Not Applicable
33 Proton Pump Inhibitors Phase 4
34 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Not Applicable
35 Neuroprotective Agents Phase 4,Phase 2,Phase 1
36 Autonomic Agents Phase 4,Phase 2,Phase 1
37 Antiemetics Phase 4,Phase 2,Phase 1
38 Fibrinolytic Agents Phase 4
39 Cytochrome P-450 CYP2C19 Inhibitors Phase 4
40 Phosphodiesterase Inhibitors Phase 4
41 Vasodilator Agents Phase 4
42 Anti-Asthmatic Agents Phase 4
43 Phosphodiesterase 3 Inhibitors Phase 4
44 Platelet Aggregation Inhibitors Phase 4
45 Respiratory System Agents Phase 4
46 Bronchodilator Agents Phase 4
47 Purinergic P2Y Receptor Antagonists Phase 4
48 Neurotransmitter Agents Phase 4
49 Purinergic P2 Receptor Antagonists Phase 4
50 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 1

Interventional clinical trials:

(show top 50) (show all 183)
# Name Status NCT ID Phase Drugs
1 Different Doses of Anti-thymocyte Globin to Treat Child Severe Aplastic Anemia Unknown status NCT01997372 Phase 4 ATG
2 Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL Completed NCT02314273 Phase 4 rhIL-11
3 A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Genotype 1 and Human Immunodeficiency Virus-1 (HIV-1) Co-infection Completed NCT00353418 Phase 4 Peginterferon alfa-2a;Ribavirin;Ribavirin
4 Stress Ulcer Prophylaxis in the Intensive Care Unit Completed NCT02467621 Phase 4 Pantoprazole
5 Eltrombopag in Children With Idiopathic Aplastic Anemia Recruiting NCT03243656 Phase 4 Eltrombopag
6 Diabetic Artery Obstruction: is it Possible to Reduce Ischemic Events With Cilostazol? Recruiting NCT02983214 Phase 4 Clopidogrel;Cilostazol
7 ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) Recruiting NCT02670564 Phase 4
8 Agents Intervening Against Delirium in Intensive Care Unit Recruiting NCT03392376 Phase 4 Haloperidol Injection
9 The Impact of Red Cell Age on Product Utilization in the Chronically Transfused Outpatient Population Unknown status NCT02393508 Phase 3
10 Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases Unknown status NCT01019876 Phase 2, Phase 3 Fludarabine;Cyclophosphamide;Cyclophosphamide 40;Cyclophosphamide 30
11 Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS) Unknown status NCT00234143 Phase 2, Phase 3 Darbepoetin
12 Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia Unknown status NCT01145976 Phase 3 Cy-ATG;Flu-ATG
13 Stem Cell Transplant for Bone Marrow Failure Syndromes Completed NCT00176878 Phase 2, Phase 3 Fludarabine monophosphate;Busulfan
14 Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT Completed NCT00774527 Phase 3 Cyclophosphamide-fludarabine-anti thymocyte globulin
15 Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder Completed NCT00755040 Phase 3 cyclosporine ophthalmic emulsion
16 Multi-Center Trial of Anti-Thymocyte Globulin in Treatment of Aplastic Anemia and Other Hematologic Disorders Completed NCT00000597 Phase 3 antilymphocyte serum;nandrolone
17 Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria Completed NCT00098280 Phase 3 Eculizumab
18 Maribavir Versus Oral Ganciclovir For The Prevention of Cytomegalovirus (CMV) Disease in Liver Transplant Recipients Completed NCT00497796 Phase 3 maribavir;ganciclovir
19 A Study of MK-3415, MK-6072, and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-001) Completed NCT01241552 Phase 3 SOC
20 A Study of MK-6072 and MK-3415A in Participants Receiving Antibiotic Therapy for Clostridium Difficile Infection (MK-3415A-002) Completed NCT01513239 Phase 3 SOC
21 Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients Not yet recruiting NCT03295058 Phase 2, Phase 3 Non ATG Conditioning regimen;GVHD Prophylaxis;ATG conditioning regimen
22 A Study Evaluating Epoetin Alfa 40,000 IU (International Units) Every Week or 80,000 IU Every Week Compared to Placebo in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes at Risk for Transfusion Terminated NCT00695396 Phase 3 Placebo;Epoetin alfa;Placebo;Epoetin alfa
23 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013) Unknown status NCT01760096 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
24 Limiting Chemotherapy Side Effects by Using Moxa Unknown status NCT02781155 Phase 1, Phase 2
25 Nandrolone Decanoate in the Treatment of Telomeropathies Unknown status NCT02055456 Phase 1, Phase 2 Nandrolone Decanoate
26 Eltrombopag for Enhancing Platelet Engraftment in Adult Patients Undergoing Cord Blood Transplantation Unknown status NCT01757145 Phase 2 Eltrombopag
27 A Single-Arm Phase 2 Study With Optimized Standard Protocol for Severe Aplastic Anemia Unknown status NCT02203396 Phase 2 rabbit ATG, Cyclosporine, Levamisole
28 Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1 Unknown status NCT02931071 Phase 2 filgrastim;plerixafor
29 Prospective Study of Mylotarg and G-CSF in Acute Myeloid Leukemia Treatment Unknown status NCT01698879 Phase 2 Mylotarg
30 Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria Unknown status NCT01642979 Phase 2 Levamisole+cyclosporin A+Glucocorticoids;cyclosporin A+Glucocorticoids;Glucocorticoids
31 Rabbit Antithymocyte Globulin Versus Campath-1H for Treating Severe Aplastic Anemia Completed NCT00065260 Phase 2 Campath-1H;r-ATG;CsA
32 Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome Completed NCT00731328 Phase 2
33 Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes Completed NCT00004143 Phase 2 Campath, Chemo and/or TBI Allo SCT
34 Three Immunosuppressive Treatment Regimens for Severe Aplastic Anemia Completed NCT00260689 Phase 2 Cyclosporine;Alemtuzumab
35 Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia Completed NCT01193283 Phase 1, Phase 2 Cyclophosphamide;Cyclosporine
36 Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes Completed NCT00004787 Phase 2 filgrastim
37 A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia Completed NCT01187017 Phase 1, Phase 2 Cyclophosphamide;Fludarabine
38 Reduced Intensity Conditioning Using CD3+/CD19+ Depletion for Non Malignant Transplantable Diseases Completed NCT02277639 Phase 2
39 Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia Completed NCT00061360 Phase 2 cyclosporine;Rapamune;ATG
40 Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003270 Phase 2 busulfan;cyclophosphamide;cyclosporine;methylprednisolone
41 Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer Completed NCT00002809 Phase 2 cyclophosphamide;methotrexate;tacrolimus
42 Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases Completed NCT00003662 Phase 2 busulfan;cyclophosphamide;cyclosporine;melphalan;methylprednisolone
43 Bortezomib to Treat Significant Complication of HSCT Completed NCT01929980 Phase 2 Bortezomib
44 Danazol for Genetic Bone Marrow and Lung Disorders Completed NCT01441037 Phase 1, Phase 2 Danazol
45 Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 Completed NCT00479115 Phase 1, Phase 2 AMD3100
46 Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia Completed NCT00229619 Phase 2 Rituximab
47 Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia Completed NCT00052832 Phase 2
48 High-Dose Immunosuppression and Autologous Transplantation for Multiple Sclerosis (HALT MS) Study Completed NCT00288626 Phase 2 Granulocyte-colony stimulating factor (G-CSF) and prednisone;Carmustine, etoposide, cytarabine, and melphalan (BEAM)
49 Antithymocyte Globulin and Cyclosporine to Treat Myelodysplasia Completed NCT00005937 Phase 2 Antithymocyte globulin;Cyclosporine
50 Study of the Efficacy and Safety of Lenalidomide in Combination With Cyclosporine A in Patients With Myelodysplastic Syndromes Completed NCT00840827 Phase 2 lenalidomide;cyclosporine A

Search NIH Clinical Center for Pancytopenia

Cochrane evidence based reviews: pancytopenia

Genetic Tests for Pancytopenia

Genetic tests related to Pancytopenia:

# Genetic test Affiliating Genes
1 Pancytopenia 29

Anatomical Context for Pancytopenia

MalaCards organs/tissues related to Pancytopenia:

41
Bone, Bone Marrow, Liver, T Cells, Kidney, Myeloid, B Cells

Publications for Pancytopenia

Articles related to Pancytopenia:

(show top 50) (show all 1057)
# Title Authors Year
1
Fever with pancytopenia: unusual presentation of extrapulmonary tuberculosis: a case report. ( 29506574 )
2018
2
Visceral leishmaniasis presenting with pancytopenia and circulating blastlike lymphocytes. ( 29930152 )
2018
3
Ecthyma Gangrenosum: Vulvar Ulcers, Pseudomonas and Pancytopenia, A Case Report of an 18- Month-Old Female. ( 29885367 )
2018
4
Approach to pancytopenia: Diagnostic algorithm for clinical hematologists. ( 29555368 )
2018
5
Anorexia nervosa-associated pancytopenia mimicking idiopathic aplastic anemia: a case report. ( 29801443 )
2018
6
Pancytopenia in a young girl with skin lesions. ( 29380733 )
2018
7
Diagnosis of GATA2 haplo-insufficiency in a young woman prompted by pancytopenia with deficiencies of B-cell and dendritic cell development. ( 29588856 )
2018
8
Fetal Hydrops Secondary to in utero Pancytopenia. ( 29972823 )
2018
9
Nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma. ( 29656748 )
2018
10
Methotrexate-induced pancytopenia in a patient with ectopic pregnancy. ( 29593825 )
2018
11
Severe pancytopenia and splenomegaly associated with felty's syndrome, both fully responsive solely to corticosteroids. ( 29531729 )
2018
12
SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies. ( 29535429 )
2018
13
Canine pancytopenia in the Mediterranean - Authors' reply. ( 29726020 )
2018
14
CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia. ( 29353154 )
2018
15
Fatal pancytopenia due to albendazole treatment for strongyloidiasis. ( 29942764 )
2018
16
Systemic lupus erythematosus presenting to haematology with pancytopenia and features of macrophage activation syndrome. ( 29467122 )
2018
17
Pancytopenia in an adult patient with thiamine-responsive megaloblastic anaemia. ( 29903777 )
2018
18
The Simplest Explanation: Pancytopenia. ( 29649461 )
2018
19
Levetiracetam Adverse Drug Reaction: Pancytopenia. ( 29899787 )
2018
20
Corrigendum to 'CD41 immune staining of micromegakaryocytes improves the diagnosis of myelodysplastic syndrome and differentiation from pancytopenia' [leukemia research. 2018; 66: 15-19]. ( 29673488 )
2018
21
Pancytopenia and Myelodysplastic Changes in Aceruloplasminemia: A Case with a Novel Pathogenic Variant in the Ceruloplasmin Gene. ( 29434149 )
2018
22
Pancytopenia and megaloblastic erythropoiesis reveal a novel GIF mutation. ( 29368379 )
2018
23
Probable fidaxomicin-induced pancytopenia. ( 29626003 )
2018
24
Lamotrigine-induced pancytopenia in bipolar disorder. ( 30033033 )
2018
25
Newly diagnosed AIDS with neurosyphilis, Kaposi sarcoma, pancytopenia, oropharyngeal candidiasis, and pseudomonal pneumonia: We shouldn't be seeing this anymore. ( 30101071 )
2018
26
Pancytopenia: a rare complication of Graves' disease. ( 29525760 )
2018
27
Unusual cause of infant pancytopenia: granulomatous bone marrow lesion with disseminated histoplasmosis. ( 29519931 )
2018
28
A rare and serious cause of pancytopenia in a patient with systemic lupus erythematosus: haemophagocytic lymphohistiocytosis. ( 30262544 )
2018
29
Unexplained pancytopenia in acute myeloid leukemia treatment. ( 30147892 )
2018
30
Answer to Photo Quiz: Pancytopenia in a young girl with skin lesions. ( 29380734 )
2018
31
Reversible pancytopenia caused by severe copper deficiency in a patient with Wilson disease. ( 29954304 )
2018
32
Azathioprine-induced pancytopenia with normal TPMT activity presenting with HSV oral ulcers. ( 30002211 )
2018
33
A Rare Cause of Pancytopenia in an Exclusively Breastfed Infant. ( 30028821 )
2018
34
Linezolid-induced pancytopenia. ( 30054325 )
2018
35
How should we manage low-dose methotrexate-induced pancytopenia in patients with rheumatoid arthritis? ( 30056523 )
2018
36
Graves Disease Causing Pancytopenia: Case Report and Literature Review. ( 30083058 )
2018
37
Vitamin B12 deficiency presenting with hyperpigmentation and pancytopenia. ( 30112325 )
2018
38
Bovine Neonatal Pancytopenia-Associated Alloantibodies Recognize Individual Bovine Leukocyte Antigen 1 Alleles. ( 30154800 )
2018
39
Case 28-2018: A 39-Year-Old Man with Epistaxis, Pain and Erythema of the Forearm, and Pancytopenia. ( 30207921 )
2018
40
Novel 1.3 Mb germline duplication in chromosome 8q21.11 by microarray comparative genomic hybridization plus single nucleotide polymorphism analysis in an adult patient with pancytopenia and urinary bladder complications. ( 30349704 )
2018
41
Renal failure and progressive pancytopenia. ( 30488885 )
2018
42
Azathioprine-Induced Pancytopenia and Septic Complications: A Probable Cause of Death. ( 28874083 )
2017
43
Unusual case of splenomegaly and pancytopenia in a returned traveller. ( 29105271 )
2017
44
Smear Campaign: Misattribution of Pancytopenia to a Tick-Borne Illness. ( 29273895 )
2017
45
Screening novel autoantigens targeted by serum IgG autoantibodies in immunorelated pancytopenia by SEREX. ( 28687989 )
2017
46
A Howling Cause of Pancytopenia. ( 29069118 )
2017
47
Fever and Pancytopenia in a Liver Transplant Recipient: Going Against the Rules of Occam's Razor. ( 28706972 )
2017
48
IVIG-Associated Maternal Pancytopenia during Treatment for Neonatal Alloimmune Thrombocytopenia. ( 28970962 )
2017
49
Successful haploidentical BMT with post-transplant cyclophosphamide for refractory autoimmune pancytopenia after cord blood transplant in pediatric myelodysplastic syndrome. ( 28067878 )
2017
50
Mutations in EFL1, an SBDS partner, are associated with infantile pancytopenia, exocrine pancreatic insufficiency and skeletal anomalies in aShwachman-Diamond like syndrome. ( 28331068 )
2017

Variations for Pancytopenia

Expression for Pancytopenia

Search GEO for disease gene expression data for Pancytopenia.

Pathways for Pancytopenia

GO Terms for Pancytopenia

Cellular components related to Pancytopenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 CSF1 CSF2 CSF3 EPO IL3 TCN2
2 extracellular region GO:0005576 9.23 CD55 CSF1 CSF2 CSF3 EPO IL3
3 telomerase holoenzyme complex GO:0005697 8.96 DKC1 TERT

Biological processes related to Pancytopenia according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.73 CSF1 CSF2 CSF3 EPO IL3 THPO
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.58 CSF2 EPO IL3
3 cytokine-mediated signaling pathway GO:0019221 9.55 CSF1 CSF2 CSF3 IL3 MPL
4 telomere maintenance via telomerase GO:0007004 9.49 DKC1 TERT
5 positive regulation of nitric-oxide synthase activity GO:0051000 9.48 DHFR TERT
6 positive regulation of Ras protein signal transduction GO:0046579 9.46 CSF1 EPO
7 positive regulation of macrophage derived foam cell differentiation GO:0010744 9.43 CSF1 CSF2
8 regulation of signaling receptor activity GO:0010469 9.43 CSF1 CSF2 CSF3 EPO IL3 THPO
9 DNA ligation GO:0006266 9.37 LIG4 MGMT
10 thrombopoietin-mediated signaling pathway GO:0038163 9.32 MPL THPO
11 cell proliferation GO:0008283 9.1 CSF1 DKC1 EPO LIG4 MPL THPO

Molecular functions related to Pancytopenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.35 CSF1 CSF2 CSF3 IL3 THPO
2 telomerase RNA binding GO:0070034 9.26 DKC1 TERT
3 telomerase activity GO:0003720 9.16 DKC1 TERT
4 cytokine activity GO:0005125 9.1 CSF1 CSF2 CSF3 EPO IL3 THPO

Sources for Pancytopenia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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