Panniculitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PNN001 MIFTS: 47	Panniculitis Categories: Muscle diseases, Skin diseases
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Aliases & Classifications for Panniculitis

MalaCards integrated aliases for Panniculitis:

Name: Panniculitis ¹² ⁷⁶ ²⁹ ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Skin diseases Muscle diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the musculoskeletal system and connective tissue

Other soft tissue disorders

Other soft tissue disorders, not elsewhere classified

Panniculitis, unspecified

External Ids:

Disease Ontology ¹² DOID:1526

ICD10 ³³ M79.3

ICD9CM ³⁵ 729.3 729.30

MeSH ⁴⁴ D015434

NCIt ⁵⁰ C112112

SNOMED-CT ⁶⁸ 22125009

UMLS ⁷³ C0030326

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Summaries for Panniculitis

MalaCards based summary : Panniculitis is related to subcutaneous panniculitis-like t-cell lymphoma and b-cell lymphomas, and has symptoms including pruritus, myalgia and exanthema. An important gene associated with Panniculitis is OTULIN (OTU Deubiquitinase With Linear Linkage Specificity), and among its related pathways/superpathways are Immune response Role of DAP12 receptors in NK cells and Apoptosis and survival Caspase cascade. The drugs Cyclophosphamide and Gemcitabine have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and neutrophil, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : ⁷⁶ Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the... more...

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Related Diseases for Panniculitis

Diseases related to Panniculitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 314)

#	Related Disease	Score	Top Affiliating Genes
1	subcutaneous panniculitis-like t-cell lymphoma	33.2	GZMB NAV3 NCAM1 TIA1 TRD
2	b-cell lymphomas	29.8	BTK FAS TIA1
3	peripheral t-cell lymphoma	29.8	GZMB NCAM1 TIA1
4	hemophagocytic lymphohistiocytosis	29.7	FAS GZMB IFNG
5	cutaneous t cell lymphoma	29.4	GZMB IFNG TIA1
6	bronchiolitis obliterans	29.2	GZMB IFNG
7	nodular nonsuppurative panniculitis	12.8
8	lupus erythematosus panniculitis	12.4
9	autoinflammation, panniculitis, and dermatosis syndrome	12.4
10	cytophagic histiocytic panniculitis	12.2
11	infantile onset panniculitis with uveitis and systemic granulomatosis	12.1
12	lipodermatosclerosis	12.0
13	panniculitis-induced localized lipodystrophy	12.0
14	localized lipodystrophy	11.9
15	proteasome-associated autoinflammatory syndrome 1	11.8
16	alpha-1-antitrypsin deficiency	11.6
17	igg4-related mesenteritis	11.6
18	peritonitis	11.5
19	acquired generalized lipodystrophy	11.3
20	proteasome-associated autoinflammatory syndrome 3	11.2
21	autoimmune lymphoproliferative syndrome	11.0
22	erythema nodosum, idiopathic	11.0
23	lymphoma	10.8
24	lupus erythematosus	10.6
25	pancreatitis	10.4
26	dermatomyositis	10.3
27	dermatitis	10.2
28	lichen sclerosus et atrophicus	10.2	GZMB TIA1
29	lymphomatoid granulomatosis	10.2	GZMB TIA1
30	viral esophagitis	10.2	GZMB TIA1
31	primary cutaneous anaplastic large cell lymphoma	10.2	GZMB TIA1
32	composite lymphoma	10.2	GZMB TIA1
33	systemic lupus erythematosus	10.2
34	vasculitis	10.2
35	hepatosplenic t-cell lymphoma	10.2	GZMB TIA1
36	choriocarcinoma of the testis	10.2	GZMB TIA1
37	arthritis	10.2
38	giardiasis	10.2	GZMB TIA1
39	lethal midline granuloma	10.2	NCAM1 TIA1
40	infiltrating lipoma	10.2	GZMB TIA1
41	multiple sclerosis	10.2
42	acinar cell carcinoma	10.2
43	necrotizing sialometaplasia	10.2	GZMB TIA1
44	rhinoscleroma	10.2	NCAM1 SERPINA1
45	alopecia	10.2
46	t-cell large granular lymphocyte leukemia	10.1	GZMB NCAM1
47	fasciitis	10.1
48	angioimmunoblastic t-cell lymphoma	10.1	GZMB TIA1
49	cystadenofibroma	10.1	NCAM1 SERPINA1
50	melanoma	10.1

Graphical network of the top 20 diseases related to Panniculitis:

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Symptoms & Phenotypes for Panniculitis

UMLS symptoms related to Panniculitis:

pruritus, myalgia, exanthema, decreased adipose tissue, other musculoskeletal symptoms referable to limbs, pain in limb, integumentary system signs and symptoms

GenomeRNAi Phenotypes related to Panniculitis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.64	FAS GZMB NAV3 PSMB8 TIA1
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.64	FAS GZMB NAV3 PSMB8 TIA1 BTK

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Drugs & Therapeutics for Panniculitis

Drugs for Panniculitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 83)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cyclophosphamide

Approved, Investigational

Phase 4

6055-19-2, 50-18-0

2907

Gemcitabine

Approved

Phase 4,Phase 1,Phase 2

95058-81-4

60750

Vincristine

Approved, Investigational

Phase 4

57-22-7, 2068-78-2

5978

Etoposide

Approved

Phase 4

33419-42-0

36462

Dexamethasone

Approved, Investigational, Vet_approved

Phase 4

50-02-2

5743

Dexamethasone acetate

Approved, Investigational, Vet_approved

Phase 4

1177-87-3

Cisplatin

Approved

Phase 4

15663-27-1

2767 441203 84093

Ifosfamide

Approved

Phase 4

3778-73-2

3690

Epirubicin

Approved

Phase 4

56420-45-2

41867

Prednisone

Approved, Vet_approved

Phase 4

53-03-2

5865

Methyltestosterone

Approved

Phase 4

58-18-4

6010

Testosterone enanthate

Approved

Phase 4

315-37-7

9416

Testosterone undecanoate

Approved, Investigational

Phase 4

5949-44-0

Testosterone

Approved, Investigational

Phase 4

58-22-0

6013

leucovorin

Approved

Phase 4,Phase 1,Phase 2

58-05-9

6006 143

Mechlorethamine

Approved, Investigational

Phase 4

51-75-2

4033

Methotrexate

Approved

Phase 4

59-05-2, 1959-05-2

126941

Doxorubicin

Approved, Investigational

Phase 4

23214-92-8

31703

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 4,Phase 1,Phase 2

59-30-3

6037

Doxil

Approved June 1999

Phase 4

31703

Pirarubicin

Investigational

Phase 4

72496-41-4

Isophosphamide mustard

Phase 4

Hormone Antagonists

Phase 4

Anti-Bacterial Agents

Phase 4,Phase 1

Antineoplastic Agents, Alkylating

Phase 4

Topoisomerase Inhibitors

Phase 4

Antibiotics, Antitubercular

Phase 4,Phase 1

Immunologic Factors

Phase 4,Phase 1,Phase 2

Antineoplastic Agents, Hormonal

Phase 4

Antimitotic Agents

Phase 4

Alkylating Agents

Phase 4

Hormones

Phase 4

Anti-Inflammatory Agents

Phase 4

Antineoplastic Agents, Phytogenic

Phase 4

Immunosuppressive Agents

Phase 4,Phase 1,Phase 2

BB 1101

Phase 4

Etoposide phosphate

Phase 4

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4

Antirheumatic Agents

Phase 4,Phase 1

glucocorticoids

Phase 4

Testosterone 17 beta-cypionate

Phase 4

insulin

Phase 4

Anabolic Agents

Phase 4

Androgens

Phase 4

Insulin, Globin Zinc

Phase 4

Folic Acid Antagonists

Phase 4,Phase 1,Phase 2

Vitamin B Complex

Phase 4,Phase 1,Phase 2

Antimetabolites

Phase 4,Phase 1,Phase 2

Folate

Phase 4,Phase 1,Phase 2

Antimetabolites, Antineoplastic

Phase 4,Phase 1,Phase 2

Interventional clinical trials:

(show all 21)

#	Name	Status	NCT ID	Phase	Drugs
1	CEOP/IVE/GDP Compared With CEOP as the First-line Therapy for Newly Diagnosed Adult Patients With PTCL	Unknown status	NCT02533700	Phase 4	CEOP/IVE/GDP chemotherapy regimen;CEOP chemotherapy regimen for 6 cycles
2	Testosterone Replacement in Metabolic Syndrome and Inflammation	Completed	NCT01123278	Phase 4	Testosterone;Placebo
3	CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell Lymphoma	Active, not recruiting	NCT01746992	Phase 4	Cyclophosphamide 750mg/m2;Vincristine 1.4mg/m2;Doxorubicin 50mg/m2;prednisone 60mg/m2;ifosfamide 2000mg/m2;pirarubicin 50mg/m2;pirarubicin 25mg/m2;Etoposide phosphate 100mg/m2;methotrexate 1500mg/m2
4	Effectiveness and Safety of Autologous ADRC for Treatment of Degenerative Damage of Knee Articular Cartilage	Completed	NCT02219113	Phase 1, Phase 2
5	Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies	Completed	NCT00481871	Phase 1, Phase 2	Pralatrexate Injection;Gemcitabine Hydrochloride
6	Effectiveness and Safety of Autologous ADRC for Treatment of Anterior Cruciate Ligament Partial Rupture	Enrolling by invitation	NCT02469792	Phase 1, Phase 2
7	Autologous Stromal Vascular Fraction of Cells for Treatment of Knee Articular Cartilage Dystrophy	Enrolling by invitation	NCT02827851	Phase 2
8	Vitamin D Status, Disease Specific and Quality of Life Outcomes in Patients With Cutaneous Lupus	Terminated	NCT01498406	Phase 2
9	Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas	Active, not recruiting	NCT01445535	Phase 1	EPOCH
10	Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory Lymphoma	Terminated	NCT00671112	Phase 1	Bortezomib;Everolimus
11	Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome	Unknown status	NCT01196845	Not Applicable
12	Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis	Completed	NCT03316001
13	Characterization of Transient Alterations of Cutaneous Sensory Nerve Function by Cryolipolysis	Completed	NCT01673113	Not Applicable
14	Diet Induced Weight Loss to Reduce Inflammation in Obese Women	Completed	NCT01699906	Not Applicable
15	GENETIC SUSCEPTIBILITY FACTOR AS A PREDICTOR OF TYPE 2 DIABETES REMISSION AND WEIGHT LOSS AFTER BARIATRIC SURGERY	Completed	NCT02405949
16	T-Cell Project: Prospective Collection of Data in Patients With Peripheral T-Cell Lymphoma	Recruiting	NCT01142674
17	Leipzig Adipose Tissue Childhood Cohort	Recruiting	NCT02208141
18	Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency	Recruiting	NCT01787409	Not Applicable
19	Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone	Recruiting	NCT03639857	Not Applicable	Topical corticosteroid
20	Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma	Active, not recruiting	NCT02652715	Not Applicable
21	Prospective Study of Functional and Quality of Life Outcomes in Panniculectomy Patients	Terminated	NCT01464658	Not Applicable

Search NIH Clinical Center for Panniculitis

Cochrane evidence based reviews: panniculitis

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Genetic Tests for Panniculitis

Genetic tests related to Panniculitis:

#	Genetic test	Affiliating Genes
1	Panniculitis ²⁹

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Anatomical Context for Panniculitis

MalaCards organs/tissues related to Panniculitis:

⁴¹

T Cells, Skin, Neutrophil, Pancreas, Liver, B Cells, Lung

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Publications for Panniculitis

Articles related to Panniculitis:

(show top 50) (show all 1187)

#	Title	Authors	Year
1	Sterile Pyogranulomatous Dermatitis and Panniculitis. ( 30390792 )	Schissler J	2019
2	Livedo Racemosa, Reticulated Ulcerations, Panniculitis and Violaceous Plaques in a 46-year-old Woman. ( 29441299 )	AgullA^ A....Yanguas I.	2018
3	Septolobular panniculitis in disseminated Lyme borreliosis. ( 29293267 )	Dittmer M.R....Liu V.	2018
4	Pancreatic panniculitis: the &quot;bright&quot; side of the moon in solid cancer patients. ( 29301491 )	Guanziroli E....Marzano A.V.	2018
5	Inherited Immunodeficiency: A New Association With Early-Onset Childhood Panniculitis. ( 29610179 )	Bader-Meunier B....Bodemer C.	2018
6	Panniculitis associated with amyopathic dermatomyositis. ( 29641712 )	Azevedo P.O....Pinto C.A.L.	2018
7	Composite cutaneous lymphoma of diffuse large B-cell lymphoma-leg type and subcutaneous panniculitis-like T-cell lymphoma. ( 29851123 )	Szablewski V....Joujoux J.M.	2018
8	Analysis of Bacterial and Fungal Nucleic Acid in Canine Sterile Granulomatous and Pyogranulomatous Dermatitis and Panniculitis. ( 29145794 )	Rosa F.B....Hoffmann A.R.	2018
9	Diffuse granulomatous panniculitis associated with anti PD-1 antibody therapy. ( 29296642 )	Jiang B....Kim K.B.	2018
10	Ultrasound of pancreatic panniculitis. ( 29736975 )	Martinez-Mera C....Roustan GullA^n G.	2018
11	Spontaneous Resolution of Idiopathic Panniculitis: Role of <sup>18</sup>F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Diagnosis and follow-up. ( 29962727 )	Verma P....Asopa R.V.	2018
12	Alpha-1 antitrypsin deficiency panniculitis: clinical and pathologic characteristics of 10 cases. ( 29707779 )	Johnson E.F....Gibson L.E.	2018
13	Subcutaneous Panniculitis-Like T-Cell Lymphoma Versus Lupus Erythematosus Panniculitis: Distinction by Means of the Periadipocytic Cell Proliferation Index. ( 29742552 )	Sitthinamsuwan P....McCalmont T.H.	2018
14	Recurrent lupus profundus-like panniculitis associated with streptococcal throat infections in an immunocompetent child. ( 29693070 )	Min M.S....Levitt J.	2018
15	Lupus erythematosus panniculitis in a 10-year-old female child with severe systemic lupus erythematosus: A case report. ( 29504978 )		2018
16	Cold Panniculitis After Ice Therapy for Supraventricular Tachycardia. ( 29698337 )		2018
17	Pancreatic panniculitis: A case series from a tertiary university hospital in Spain. ( 29741276 )		2018
18	Mesenteric Panniculitis Presenting as Fever of Unknown Etiology in a Patient with History of Abdominal Surgery. ( 29670775 )		2018
19	A Case of Refractory Subcutaneous Panniculitis-like T-cell Lymphoma with Bone Marrow and Lung Involvement Treated Successfully with Oral Etoposide. ( 29881869 )		2018
20	Chronic pancreatitis with multiple pseudocysts and pancreatic panniculitis: A case report. ( 29851820 )		2018
21	Intravascular large B-cell lymphoma presenting as panniculitis clinically: a case report. ( 29568849 )		2018
22	Pancreatic panniculitis as a presentation symptom of acinar cell carcinoma. ( 29527901 )		2018
23	Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy. ( 29693065 )		2018
24	Breast panniculitis with liquefactive fat necrosis: A case report. ( 29904432 )		2018
25	An Autopsy Case of Mesenteric Panniculitis with Massive Pleural Effusions. ( 29298971 )		2018
26	Geometric alopecia associated with lupus erythematosus panniculitis of the scalp: a case series of nine Korean patients. ( 29619994 )		2018
27	Mesenteric Panniculitis-First Case Series After Bariatric Surgery. ( 29313276 )		2018
28	Evaluation of mesenteric panniculitis with computed tomography: benign condition or paraneoplastic syndrome? ( 29914254 )		2018
29	Pancreatic acinar cell carcinoma-induced panniculitis. ( 30128347 )	Singh S...Burrall B	2018
30	Distinctive lupus panniculitis of scalp with linear alopecia along Blaschko's lines: a review of the literature. ( 30074627 )	Lueangarun S...Tempark T	2018
31	Cutaneous Manifestation of Alpha-1 Antitrypsin Deficiency: A Case of Panniculitis. ( 30078886 )	Lopes S...Mota A	2018
32	Lobular panniculitis associated with chikungunya fever: A case report. ( 30406015 )	Sangmala S...Auepemkiate S	2018
33	Pancreatic panniculitis as the initial presentation of intrahepatic cholangiocarcinoma. ( 30023419 )	Montes de Oca MK...Jamison RA	2018
34	Cytophagic Histiocytic Panniculitis Associated with Myelodysplastic Syndrome. ( 30226527 )	Kimura R...Yamamoto O	2018
35	Dermatomyositis panniculitis: a clinicopathological and immunohistochemical study of 18 cases. ( 29524269 )	Santos-Briz A...Requena L	2018
36	Hematopoietic stem cell transplantation for subcutaneous panniculitis-like T-cell lymphoma: single center experience in an Asian population. ( 30547418 )	Lin TA...Gau JP	2018
37	Hemophagocytic lymphohistiocytosis: A rare, potentially fatal complication in subcutaneous panniculitis like T cell lymphoma. ( 30289114 )	Sirka CS...Panda D	2018
38	Nodular Panniculitis with Hemophagocytic Lymphohistiocytosis. ( 30511689 )	Liu H...Xie QB	2018
39	The coexistence of lupus erythematosus panniculitis and subcutaneous panniculitis-like T-cell lymphoma in the same patient. ( 29892661 )	Wu X...Ko C	2018
40	Relapsed subcutaneous panniculitis-like T cell lymphoma evaluated by FDG PET/CT: A clinical case report. ( 30431571 )	Dong P...Li L	2018
41	Clinicopathologic, immunophenotypic, and molecular analysis of subcutaneous panniculitis-like T-cell lymphoma: A retrospective study in a tertiary care center. ( 30350476 )	Rutnin S...Boonsakan P	2018
42	Pancreatitis, Panniculitis, and Polyarthritis. ( 30273266 )	Chattopadhyay A...Jain S	2018
43	Pancreatitis Panniculitis Polyarthritis Syndrome with multiple bone infarcts. ( 30351366 )	Agarwal S...Vikram N	2018
44	Panniculitis, pancreatitis, and polyarthritis: a rare clinical syndrome. ( 29529121 )	Graham PM...Gildenberg SR	2018
45	Lupus panniculitis refractory to multiple therapies treated successfully with rituximab: A case report and literature review. ( 28856662 )	Prieto-Torres L...Requena L	2018
46	Clues in Histopathological Diagnosis of Panniculitis. ( 29470303 )	Llamas Velasco M...Fern?ndez Figueras MT	2018
47	Comment on "Bumps in the Road: Panniculitis in Children and Adolescents Treated with Vemurafenib". ( 29575074 )	Bhat T...Coughlin CC	2018
48	Lymphocytic Lobular Panniculitis: A Diagnostic Challenge. ( 29594104 )	Alberti-Violetti S...Berti E	2018
49	Panniculitis Due to Atypical Mycobacteria After Mesotherapy. ( 29859618 )	Garc?a-Harana C...de Troya-Mart?n M	2018
50	A case of deadly panniculitis. ( 29970609 )	Yuson C...Hissaria P	2018

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Genes for Panniculitis

Genes related to Panniculitis (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	OTULIN	OTU Deubiquitinase With Linear Linkage Specificity	Protein Coding	31.98	DISEASES inferred ¹⁵ GeneCards inferred via : Disorders Variants (show sections)
2	TIA1	TIA1 Cytotoxic Granule Associated RNA Binding Protein	Protein Coding	31.96	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	12956685
3	SERPINA1	Serpin Family A Member 1	Protein Coding	31.69	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	15389208 9039946 19218787 (more) 16327507 16088434 17136953
4	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	23.37	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	GZMB	Granzyme B	Protein Coding	23.37	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	PSMB8	Proteasome Subunit Beta 8	Protein Coding	21.79	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	NAV3	Neuron Navigator 3	Protein Coding	20.67	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	IFNG	Interferon Gamma	Protein Coding	20.23	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	FAS	Fas Cell Surface Death Receptor	Protein Coding	19.95	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	BTK	Bruton Tyrosine Kinase	Protein Coding	19.72	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	TRD	T Cell Receptor Delta Locus	Protein Coding	16.9	GeneCards inferred via : Publications (show sections)

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Variations for Panniculitis

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Expression for Panniculitis

Search GEO for disease gene expression data for Panniculitis.

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Pathways for Panniculitis

Pathways related to Panniculitis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Immune response Role of DAP12 receptors in NK cells ²² Show member pathways Immune response CD16 signaling in NK cells ²² Natural killer cell mediated cytotoxicity ³⁷	12.06	FAS GZMB IFNG
2	Apoptosis and survival Caspase cascade ²² Show member pathways Apoptosis and survival FAS signaling cascades ²² Breakdown of the nuclear lamina ⁶⁶ Caspase cascade in apoptosis ¹ Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation ¹ FasL/ CD95L signaling ⁶⁶ Influenza A virus infection ¹	11.76	FAS GZMB PSMB8
3	NF-kappaB Signaling ⁴	11.68	BTK FAS GZMB IFNG NCAM1 OTULIN
4	Apoptosis and Autophagy ⁴	11.6	FAS GZMB TIA1
5	Photodynamic therapy-induced AP-1 survival signaling. ¹	11.08	FAS IFNG
6	Innate Lymphoid Cell Differentiation Pathways ⁶⁵	11.03	GZMB IFNG NCAM1
7	African trypanosomiasis ³⁷	10.8	FAS IFNG

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GO Terms for Panniculitis

Biological processes related to Panniculitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	apoptotic process	GO:0006915	9.02	BTK FAS GZMB IFNG TIA1
2	extrinsic apoptotic signaling pathway	GO:0097191	8.96	FAS IFNG

Sources

Sources for Panniculitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia