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MCID: PPL016
MIFTS: 26

Papillary Adenofibroma

Categories: Cancer diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Papillary Adenofibroma

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MalaCards integrated aliases for Papillary Adenofibroma:

Name: Papillary Adenofibroma 12 15 71

Classifications:

MalaCards categories:
Global: Cancer diseases
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External Ids:

Disease Ontology 12 DOID:5479
NCIt 49 C8986
UMLS 71 C1377850
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Summaries for Papillary Adenofibroma

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Disease Ontology : 12 An adenofibroma that is characterized by finger-like projections on histology.

MalaCards based summary : Papillary Adenofibroma is related to adenofibroma and congenital granular cell tumor. An important gene associated with Papillary Adenofibroma is PTEN (Phosphatase And Tensin Homolog), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Platelet Aggregation Inhibitor Pathway, Pharmacodynamics. Affiliated tissues include cervix, uterus and ovary, and related phenotypes are hematopoietic system and homeostasis/metabolism

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Related Diseases for Papillary Adenofibroma

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Diseases related to Papillary Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 213)
# Related Disease Score Top Affiliating Genes
1 adenofibroma 10.6
2 congenital granular cell tumor 10.2 CD34 CD2AP
3 medulloadrenal hyperfunction 10.2 VWF F3
4 esophagus sarcoma 10.2 CD34 CD2AP
5 pediatric angiosarcoma 10.2 VWF CD34
6 subungual glomus tumor 10.2 CD34 CD2AP
7 clear cell meningioma 10.2 CD34 CD2AP
8 heart cancer 10.1 CD34 CD2AP
9 kaposiform hemangioendothelioma 10.1 VWF CD34
10 lymphangiosarcoma 10.1 VWF CD34
11 respiratory system benign neoplasm 10.1 PTEN CD34
12 capillary lymphangioma 10.1 VWF CD34
13 thyroid angiosarcoma 10.1 VWF CD34
14 acquired von willebrand syndrome 10.1 VWF F3
15 carotid artery thrombosis 10.1 VWF F3
16 angiodysplasia 10.1 VWF F3
17 factor xii deficiency 10.1 VWF F3
18 capillary hemangioma 10.1 VWF CD34
19 uterine benign neoplasm 10.1 PTEN CD34
20 adenosarcoma 10.1
21 cervical adenofibroma 10.1
22 central nervous system benign neoplasm 10.1 PTEN CD34
23 capillary disease 10.1 VWF CD34
24 hemophilia a 10.1 VWF F3
25 drug-induced lupus erythematosus 10.1 VWF CD34
26 lipomatosis, multiple 10.1 PTEN CD34
27 cardiovascular cancer 10.0 VWF CD34
28 retinal vein occlusion 10.0 F3 F2
29 vascular cancer 10.0 VWF CD34
30 achenbach syndrome 10.0 F3 F2
31 intermediate coronary syndrome 10.0 VWF F3
32 klippel-trenaunay-weber syndrome 10.0 F2 CD2AP
33 thrombasthenia 10.0 F3 F2
34 fournier gangrene 10.0 F3 F2
35 synovial angioma 10.0 F3 F2
36 blue toe syndrome 10.0 F3 F2
37 giant cell glioblastoma 10.0 PTEN CD34
38 emphysematous cholecystitis 10.0 F3 F2
39 femoral neuropathy 10.0 F3 F2
40 lateral sinus thrombosis 10.0 F3 F2
41 dic in newborn 10.0 F3 F2
42 waterhouse-friderichsen syndrome 10.0 F3 F2
43 cavernous sinus thrombosis 10.0 F3 F2
44 hemopneumothorax 10.0 F3 F2
45 lemierre's syndrome 10.0 F3 F2
46 gastric hemangioma 10.0 F3 F2
47 ankylosing spondylitis 1 10.0 F3 F2
48 intracranial sinus thrombosis 10.0 F3 F2
49 hemopericardium 10.0 F3 F2
50 epidural abscess 10.0 F3 F2

Graphical network of the top 20 diseases related to Papillary Adenofibroma:



Diseases related to Papillary Adenofibroma
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Symptoms & Phenotypes for Papillary Adenofibroma

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MGI Mouse Phenotypes related to Papillary Adenofibroma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.73 CD2AP CD34 F2 F3 PTEN VWF
2 homeostasis/metabolism MP:0005376 9.7 AFP CD2AP CD34 F2 F3 PTEN
3 immune system MP:0005387 9.43 CD2AP CD34 F2 F3 PTEN VWF
4 neoplasm MP:0002006 8.92 AFP CD34 F3 PTEN
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Drugs & Therapeutics for Papillary Adenofibroma

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Search Clinical Trials , NIH Clinical Center for Papillary Adenofibroma

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Genetic Tests for Papillary Adenofibroma

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Anatomical Context for Papillary Adenofibroma

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MalaCards organs/tissues related to Papillary Adenofibroma:

40
Cervix, Uterus, Ovary
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Publications for Papillary Adenofibroma

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Articles related to Papillary Adenofibroma:

(show all 18)
# Title Authors PMID Year
1
Pitfalls of Frozen Section in Gynecological Pathology: A Case of Ovarian Serous Surface Papillary Adenofibroma Imitating Malignancy. 61
30563377 2019
2
Serous surface papillary adenofibroma of the ovary: impersonator of ovarian malignancy. 61
24484475 2014
3
Unusual presentation of rare case of papillary adenofibroma of cervix in a young woman. 61
22606457 2012
4
Mammary-like gland adenoma of the vulva: review of 46 cases. 61
19404851 2009
5
Papillary adenofibroma of the cervix: a case report. 61
16041681 2005
6
[Endometrial adenofibroma]. 61
11462961 2001
7
Papillary adenofibroma of cervix. 61
10638132 1999
8
Papillary adenofibroma of the uterine cervix. A case report. 61
8927449 1996
9
[The malignant potential of adenofibroma and cystadenofibroma of the ovary and mesovarium. 118 cases including 13 proliferative and 5 carcinomatous]. 61
8463564 1993
10
Papillary adenofibroma of the uterus. Report of a case involved by adenocarcinoma and review of the literature. 61
1595599 1992
11
Papillary adenofibroma of the cervix. An unusual tumour of the cervix. 61
3505509 1987
12
Papillary adenofibroma of the endometrium: case report and review of the literature. 61
6489832 1984
13
Bilateral papillary adenofibroma of the fallopian tube. 61
7468528 1981
14
[Papillary adenofibroma of the uterus: fact or fancy? (author's transl)]]. 61
510899 1979
15
[Papillary polypoid adenofibroma of the uterine body (author's transl)]. 61
422027 1979
16
Adenomyomatosis of endometrium and endocervix-a hamartoma. 61
1155381 1975
17
Papillary adenofibroma of the uterus: a benign mesodermal mixed tumor of Müllerian orgin. 61
4364374 1973
18
Papillary adenofibroma of the uterine cervix. 61
5558981 1971
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Variations for Papillary Adenofibroma

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Expression for Papillary Adenofibroma

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Search GEO for disease gene expression data for Papillary Adenofibroma.
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Pathways for Papillary Adenofibroma

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Pathways related to Papillary Adenofibroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Formation of Fibrin Clot (Clotting Cascade) 65
Show member pathways
 11.33 VWF F3 F2
2
Platelet Aggregation Inhibitor Pathway, Pharmacodynamics 60
10.96 VWF F2
3
Complement and coagulation cascades 36 1
10.96 VWF F3 F2
4
FOXA2 and FOXA3 transcription factor networks 1
10.8 F2 AFP
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GO Terms for Papillary Adenofibroma

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Cellular components related to Papillary Adenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 9.13 VWF F3 F2
2 extracellular region GO:0005576 9.1 VWF PTEN F3 F2 CD34 AFP

Biological processes related to Papillary Adenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.33 VWF F3 F2
2 cell motility GO:0048870 9.32 PTEN CD34
3 positive regulation of protein localization to nucleus GO:1900182 9.26 F2 CD2AP
4 blood coagulation, intrinsic pathway GO:0007597 8.96 VWF F2
5 hemostasis GO:0007599 8.8 VWF F3 F2
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Sources for Papillary Adenofibroma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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