MCID: PPL001
MIFTS: 32

Papillary Adenoma

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Papillary Adenoma

MalaCards integrated aliases for Papillary Adenoma:

Name: Papillary Adenoma 12 15 73
Glandular Papilloma 12 73
Adenoma 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3172
MeSH 44 D000236
NCIt 50 C79951
SNOMED-CT 68 189620009 86143001

Summaries for Papillary Adenoma

MalaCards based summary : Papillary Adenoma, also known as glandular papilloma, is related to metanephric adenoma and ovarian germ cell teratoma. An important gene associated with Papillary Adenoma is KRT7 (Keratin 7), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include kidney, lung and pancreas, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Papillary Adenoma

Diseases related to Papillary Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 metanephric adenoma 30.4 KRT7 VIM
2 ovarian germ cell teratoma 30.2 KRT7 NKX2-1
3 oncocytoma 29.8 KRT7 VIM
4 papillary adenocarcinoma 29.6 KRT7 NKX2-1 VIM
5 teratoma 29.5 KRT7 NKX2-1
6 papillary carcinoma 28.7 KRT7 NKX2-1
7 renal cell carcinoma, nonpapillary 28.0 KRT7 NAPSA NKX2-1 OGG1 VIM
8 intracystic papillary adenoma 12.0
9 eccrine papillary adenoma 12.0
10 extrahepatic bile duct papillary adenoma 12.0
11 type 1 papillary adenoma of the kidney 11.9
12 type 2 papillary adenoma of the kidney 11.9
13 aggressive digital papillary adenocarcinoma 11.4
14 chromophil adenoma of the kidney 11.3
15 adenoma 10.6
16 parachordoma 10.5 KRT7 VIM
17 adenoid squamous cell carcinoma 10.5 KRT7 VIM
18 malignant mixed mullerian tumor 10.5 KRT7 VIM
19 nodular hidradenoma 10.5 KRT7 VIM
20 benign metastasizing leiomyoma 10.5 KRT7 VIM
21 monophasic synovial sarcoma 10.5 KRT7 VIM
22 spiradenoma 10.5 KRT7 VIM
23 medulloepithelioma 10.5 KRT7 VIM
24 adenomatoid tumor 10.5 KRT7 VIM
25 hidradenoma 10.5 KRT7 VIM
26 solid adenocarcinoma with mucin production 10.5 KRT7 NKX2-1
27 mucinous cystadenocarcinoma 10.5 KRT7 VIM
28 lung acinar adenocarcinoma 10.5 KRT7 NKX2-1
29 small cell carcinoma of the bladder 10.5 KRT7 NKX2-1
30 endocervical adenocarcinoma 10.5 KRT7 VIM
31 ovarian germ cell cancer 10.5 KRT7 NKX2-1
32 spindle cell sarcoma 10.5 KRT7 VIM
33 mucinous bronchioloalveolar adenocarcinoma 10.4 KRT7 NKX2-1
34 bronchiolo-alveolar adenocarcinoma 10.4 KRT7 NKX2-1
35 papillary serous adenocarcinoma 10.4 KRT7 NKX2-1
36 intestinal perforation 10.4 KRT7 NKX2-1
37 endodermal sinus tumor 10.4 KRT7 VIM
38 pulmonary sclerosing hemangioma 10.4 KRT7 NKX2-1
39 pleomorphic carcinoma 10.4 KRT7 NKX2-1
40 granulosa cell tumor of the ovary 10.4 KRT7 VIM
41 sclerosing hemangioma 10.4 KRT7 NKX2-1
42 angiolipoma 10.4 MTFMT VIM
43 secretory meningioma 10.4 KRT7 VIM
44 krukenberg carcinoma 10.3 KRT7 NAPSA
45 cystic teratoma 10.3 KRT7 NKX2-1
46 pericardial mesothelioma 10.3 KRT7 VIM
47 horseshoe kidney 10.3 KRT7 NKX2-1
48 ovarian benign neoplasm 10.3 KRT7 NAPSA
49 ovarian cystic teratoma 10.3 KRT7 NKX2-1
50 thymus adenocarcinoma 10.3 KRT7 NAPSA

Graphical network of the top 20 diseases related to Papillary Adenoma:



Diseases related to Papillary Adenoma

Symptoms & Phenotypes for Papillary Adenoma

GenomeRNAi Phenotypes related to Papillary Adenoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.44 VIM
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.44 KRT5
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.44 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.44 KRT5
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.44 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.44 VIM
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.44 KRT7
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.44 KRT7 KRT5
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.44 KRT7
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.44 KRT7 VIM KRT5

Drugs & Therapeutics for Papillary Adenoma

Search Clinical Trials , NIH Clinical Center for Papillary Adenoma

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: adenoma

Genetic Tests for Papillary Adenoma

Anatomical Context for Papillary Adenoma

MalaCards organs/tissues related to Papillary Adenoma:

41
Kidney, Lung, Pancreas, Prostate, Bone, Thyroid, B Cells

Publications for Papillary Adenoma

Articles related to Papillary Adenoma:

(show top 50) (show all 94)
# Title Authors Year
1
Pulmonary Papillary Adenoma: Report of Two Cases. ( 29017679 )
2017
2
A Case of Syringocystadenoma Papilliferum with Tubular Papillary Adenoma of the Chest. ( 28502963 )
2017
3
Papillary adenoma of the common bile duct: Infrequent pathology, novel endoscopic resolution, rare complication. A case report. ( 26993161 )
2016
4
Cytomorphologic findings and differential diagnosis of pulmonary papillary adenoma: A case report and literature review. ( 27040894 )
2016
5
Tubulopapillary Cystic Adenoma With Apocrine Differentiation: A Unifying Concept for Syringocystadenoma Papilliferum, Apocrine Gland Cyst, and Tubular Papillary Adenoma. ( 28033156 )
2016
6
Pulmonary papillary adenoma presenting in central portion: a case report. ( 26474555 )
2015
7
Papillary adenoma arising from an extensive biliary low-grade intraepithelial neoplasia. ( 26477935 )
2015
8
A rare case of pulmonary papillary adenoma in old aged woman: a brief case report. ( 24627699 )
2014
9
Microscopic small clear cell papillary lesion of the kidney with long-term hemodialysis patient: is this clear cell papillary adenoma? ( 25622340 )
2014
10
Local excision of papillary adenoma in patients with high surgical risk for pancreaticoduodenectomy. ( 25626947 )
2014
11
Pulmonary sclerosing papillary adenoma. ( 23865575 )
2013
12
Pulmonary papillary adenoma: a case report and review of the literature. ( 23328145 )
2013
13
Renal papillary adenoma in autosomal dominant polycystic kidney disease. ( 24241088 )
2013
14
A case of pulmonary papillary adenoma: possible relationship between tumor histogenesis/tumorigenesis and fibroblast growth factor receptor 2 IIIb. ( 22924850 )
2012
15
A rare case of giant papillary adenoma of the breast. ( 22525553 )
2012
16
Papillary adenoma of the lung with a peculiar raw macroscopic feature. ( 21790862 )
2011
17
Papillary adenoma arising in the left hepatic duct: an unusual tumour in an uncommon location. ( 20545030 )
2010
18
Successful removal of a papillary adenoma by using the cap technique. ( 20417506 )
2010
19
Papillary adenoma of the extrahepatic biliary tract--a rare cause of obstructive jaundice. ( 20690568 )
2010
20
Inflammatory myofibroblastic tumour of the kidney with a papillary adenoma. ( 20085528 )
2010
21
Pulmonary papillary adenoma. ( 20941571 )
2010
22
Papillary adenoma of the lung. ( 19670704 )
2009
23
Huge renal cyst with parietal renal cell carcinoma, osseous metaplasia and a papillary adenoma: a case report with unique clinicopathological features and literature review. ( 18080136 )
2008
24
Papillary adenoma of the distal common bile duct associated with a synchronous carcinoma of the peri-ampullary duodenum. ( 18326932 )
2008
25
Loss of heterozygosity of DNA repair gene, hOGG1, in renal cell carcinoma but not in renal papillary adenoma. ( 18477212 )
2008
26
Renal oncocytosis and multiple papillary adenomas with oncocytoma as dominant nodule coexisting with papillary carcinoma in a patient with diabetic glomerulosclerosis, acquired renal cystic disease and B cell lymphoma. ( 19132988 )
2008
27
Renal papillary adenoma--a putative precursor of papillary renal cell carcinoma. ( 17056094 )
2007
28
Image of the month. Papillary adenoma of the cystic duct. ( 16549700 )
2006
29
Aggressive digital papillary adenoma-adenocarcinoma. ( 16687341 )
2006
30
Digital papillary adenoma (ADPA) and aggressive digital papillary adenocarcinoma (AdPACa). ( 16314709 )
2005
31
Pulmonary papillary adenoma-like tumour arising in ovarian teratoma. ( 15141313 )
2004
32
Common bile duct papillary adenoma causing obstructive jaundice: case report and review of the literature. ( 15156955 )
2004
33
Cytologic characteristics of pulmonary papillary adenoma. A case report. ( 15085761 )
2004
34
Papillary adenoma of the prostatic urethra: report of two cases. ( 12887371 )
2003
35
TTF-1 is useful in the diagnosis of pulmonary papillary adenoma. ( 14511264 )
2003
36
Metanephric adenoma lacks the gains of chromosomes 7 and 17 and loss of Y that are typical of papillary renal cell carcinoma and papillary adenoma. ( 14559991 )
2003
37
Microcystic papillary adenoma of the nose: a case report. ( 15027732 )
2003
38
Long-term follow-up of intraductal papillary adenoma of the pancreas. ( 12424574 )
2002
39
[Differentiated papillary kidney tumors. Differentiation between metanephric adenoma and papillary adenoma]. ( 12185784 )
2002
40
Synchronous detection of a pulmonary papillary adenoma and lung metastases in a patient with osteosarcoma in relapse. ( 11813181 )
2002
41
Papillary adenoma of the kidney with mucinous secretion. ( 11332693 )
2001
42
Papillary adenoma of the bile duct. ( 11375588 )
2001
43
Aggressive digital papillary adenocarcinoma (aggressive digital papillary adenoma and adenocarcinoma revisited). ( 10843279 )
2000
44
Papillary adenoma of the distal common bile duct. ( 10452691 )
1999
45
Papillary adenoma of the large intestine: a historical perspective. ( 9731879 )
1998
46
Papillary adenoma of endolymphatic sac origin: a temporal bone tumor in von Hippel-Lindau disease. Case report. ( 9285613 )
1997
47
Aggressive papillary adenoma of the cerebellopontine angle: case report of an endolymphatic sac tumor. ( 9074741 )
1997
48
Radiologic features of papillary adenoma and papillomatosis of the biliary tract. ( 9000364 )
1997
49
p53 mutations in two patients with intraductal papillary adenoma of the pancreas. ( 9045952 )
1996
50
Papillary adenoma of type II pneumocytes might have malignant potential. ( 8688974 )
1996

Variations for Papillary Adenoma

Expression for Papillary Adenoma

Search GEO for disease gene expression data for Papillary Adenoma.

Pathways for Papillary Adenoma

Pathways related to Papillary Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.62 KRT5 KRT7 VIM
2
Show member pathways
10.83 KRT5 KRT7 VIM

GO Terms for Papillary Adenoma

Cellular components related to Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.8 KRT5 KRT7 VIM

Molecular functions related to Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.62 KRT5 VIM

Sources for Papillary Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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