Papillary Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PPL002 MIFTS: 50	Papillary Carcinoma Categories: Cancer diseases
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Aliases & Classifications for Papillary Carcinoma

MalaCards integrated aliases for Papillary Carcinoma:

Name: Papillary Carcinoma ¹² ¹⁵

Carcinoma, Papillary ⁴⁴ ⁷³

Carcinoma Papillary ⁵⁵

Classifications:

MalaCards categories:
Global: Cancer diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3113

MeSH ⁴⁴ D002291

NCIt ⁵⁰ C2927

SNOMED-CT ⁶⁸ 189562005 25910003

UMLS ⁷³ C0007133

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Summaries for Papillary Carcinoma

Disease Ontology : ¹² A carcinoma that is derives from epithelial cells with finger like projections.

MalaCards based summary : Papillary Carcinoma, also known as carcinoma, papillary, is related to primary peritoneal carcinoma and renal cell carcinoma, papillary, 1. An important gene associated with Papillary Carcinoma is TG (Thyroglobulin), and among its related pathways/superpathways are Endometrial cancer and Gastric cancer. The drugs BCG vaccine and Adjuvants, Immunologic have been mentioned in the context of this disorder. Affiliated tissues include thyroid, lymph node and breast, and related phenotypes are cellular and homeostasis/metabolism

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Related Diseases for Papillary Carcinoma

Diseases related to Papillary Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 341)

#	Related Disease	Score	Top Affiliating Genes
1	primary peritoneal carcinoma	33.7	ERBB2 PGR RET
2	renal cell carcinoma, papillary, 1	33.4	BRAF ERBB2 KRT7 MET PAX8
3	breast papillary carcinoma	33.3	ERBB2 NCOA4 PGR RET
4	papillary serous adenocarcinoma	32.2	KRT20 KRT7 NKX2-1 PGR
5	thyroid cancer, nonmedullary, 1	30.8	BRAF LGALS3 NCOA4 NKX2-1 PAX8 RET
6	thyroiditis	30.7	CALCA RET TG TPO TSHR
7	suppurative thyroiditis	30.6	CALCA TG
8	histiocytic sarcoma	30.5	LGALS3 MUC1
9	intracystic papillary adenoma	30.4	ERBB2 PGR
10	thyroid carcinoma, familial medullary	30.2	CALCA NKX2-1 RET TG
11	thymus cancer	30.2	KRT7 MUC1 NKX2-1
12	papillary adenoma	30.1	KRT7 NKX2-1
13	cystic teratoma	30.0	KRT20 KRT7 NKX2-1
14	struma ovarii	29.7	BRAF NKX2-1 RET TG TSHR
15	mucoepidermoid carcinoma	29.7	CALCA ERBB2 KRT7 MUC1 TG
16	subacute thyroiditis	29.7	TG TPO TSHR
17	adenocarcinoma in situ	29.5	KRT20 KRT7 PAX8
18	hyperthyroidism	29.2	TG TPO TSHR
19	ductal carcinoma in situ	29.2	CDH1 ERBB2 MUC1 PGR
20	squamous cell carcinoma	29.1	BRAF CDH1 ERBB2 KRT19 MUC1
21	in situ carcinoma	29.1	CDH1 ERBB2 PGR
22	renal cell carcinoma, nonpapillary	29.1	CDH1 KRT19 KRT20 KRT7 MET MUC1
23	adenocarcinoma	29.0	BRAF CDH1 ERBB2 MUC1 RET
24	malignant struma ovarii	28.9	KRT19 LGALS3 NCOA4 NKX2-1 RET TG
25	lymphoepithelioma-like carcinoma	28.7	CDH1 KRT20 KRT7 MUC1
26	neonatal hypothyroidism	28.6	PAX8 TG TPO TSHR
27	multinodular goiter	28.2	CALCA NKX2-1 PAX8 TG TPO TSHR
28	congenital hypothyroidism	28.2	NKX2-1 PAX8 TG TPO TSHR
29	thyroid cancer, nonmedullary, 2	28.1	BRAF CALCA KRT19 LGALS3 NKX2-1 PAX8
30	hypothyroidism	28.0	CALCA NKX2-1 PAX8 RET TG TPO
31	hashimoto thyroiditis	27.9	CALCA KRT19 LGALS3 RET TG TPO
32	adenoid cystic carcinoma	27.8	CDH1 ERBB2 KRT19 KRT20 KRT7 MUC1
33	goiter	27.7	CALCA LGALS3 NKX2-1 PAX8 TG TPO
34	ovarian cancer	27.3	BRAF CDH1 CLDN3 ERBB2 KRT7 MUC1
35	anaplastic thyroid cancer	27.2	BRAF CDH1 MET NKX2-1 PAX8 TG
36	follicular adenoma	27.2	CALCA KRT19 LGALS3 NKX2-1 PAX8 RET
37	thyroid cancer	23.7	BRAF CALCA CDH1 KRT19 LGALS3 MET
38	tall cell variant papillary carcinoma	12.1
39	gallbladder papillary carcinoma	12.1
40	primary peritoneal serous/papillary carcinoma	12.0
41	ovary papillary carcinoma	12.0
42	thyroid carcinoma, papillary, with papillary renal neoplasia	11.9
43	kidney pelvis papillary carcinoma	11.9
44	familial renal papillary carcinoma	11.9
45	bladder urothelial papillary carcinoma	11.9
46	columnar cell variant papillary carcinoma	11.9
47	papillary carcinoma of the cervix uteri	11.9
48	penis papillary carcinoma	11.8
49	papillary carcinoma of the corpus uteri	11.8
50	papillary thymic adenocarcinoma	11.2

Graphical network of the top 20 diseases related to Papillary Carcinoma:

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Symptoms & Phenotypes for Papillary Carcinoma

MGI Mouse Phenotypes related to Papillary Carcinoma:

⁴⁶ (show all 14)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	10.34	LGALS3 ERBB2 BRAF KRT19 CDH1 KRT7
2	homeostasis/metabolism	MP:0005376	10.28	KRT7 LGALS3 ERBB2 BRAF CDH1 PAX8
3	endocrine/exocrine gland	MP:0005379	10.26	ERBB2 BRAF KRT19 CDH1 RET PAX8
4	cardiovascular system	MP:0005385	10.24	ERBB2 BRAF KRT19 CDH1 NKX2-1 LGALS3
5	growth/size/body region	MP:0005378	10.2	CDH1 ERBB2 BRAF KRT19 NKX2-1 PAX8
6	mortality/aging	MP:0010768	10.15	CDH1 ERBB2 BRAF KRT19 PGR NKX2-1
7	digestive/alimentary	MP:0005381	10.11	ERBB2 BRAF KRT19 CDH1 NKX2-1 LGALS3
8	embryo	MP:0005380	10.1	ERBB2 BRAF KRT19 CDH1 PGR PAX8
9	neoplasm	MP:0002006	10.02	LGALS3 ERBB2 BRAF KRT19 CDH1 RET
10	limbs/digits/tail	MP:0005371	9.95	ERBB2 PAX8 MET PGR TSHR RET
11	normal	MP:0002873	9.81	ERBB2 BRAF KRT19 CDH1 NKX2-1 PAX8
12	no phenotypic analysis	MP:0003012	9.8	KRT19 CDH1 PGR NKX2-1 PAX8 MET
13	reproductive system	MP:0005389	9.7	CLDN3 LGALS3 ERBB2 BRAF KRT19 CDH1
14	skeleton	MP:0005390	9.28	ERBB2 BRAF KRT19 NKX2-1 LGALS3 PAX8

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Drugs & Therapeutics for Papillary Carcinoma

Drugs for Papillary Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 59)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

BCG vaccine

Investigational

Phase 3

Adjuvants, Immunologic

Phase 3

Vaccines

Phase 3

Alkylating Agents

Phase 3,Phase 2

Anti-Bacterial Agents

Phase 3,Phase 2,Phase 1

Antibiotics, Antitubercular

Phase 3,Phase 2

Mitomycins

Phase 3

Nucleic Acid Synthesis Inhibitors

Phase 3

Everolimus

Approved

Phase 2

159351-69-6

6442177

Miconazole

Approved, Investigational, Vet_approved

Phase 2

22916-47-8

4189

Sirolimus

Approved, Investigational

Phase 2

53123-88-9

5284616 6436030 46835353

Iodine

Approved, Investigational

Phase 2,Phase 1,Not Applicable

7553-56-2

807

Sunitinib

Approved, Investigational

Phase 2

341031-54-7, 557795-19-4

5329102

Paclitaxel

Approved, Vet_approved

Phase 1, Phase 2,Phase 2

33069-62-4

36314

Carboplatin

Approved

Phase 2,Phase 1

41575-94-4

10339178 498142 38904

Lenvatinib

Approved, Investigational

Phase 2

417716-92-8

Pembrolizumab

Approved

Phase 2

1374853-91-4

Trametinib

Approved

Phase 2

871700-17-3

11707110

Trastuzumab

Approved, Investigational

Phase 2

180288-69-1

9903

Lenalidomide

Approved

Phase 1, Phase 2

191732-72-6

216326

Cediranib

Investigational

Phase 1, Phase 2

288383-20-0

9933475

Maleic acid

Experimental

Phase 1, Phase 2

110-16-7

444266

Anti-Infective Agents

Phase 2,Phase 1,Not Applicable

Anti-Infective Agents, Local

Phase 2,Not Applicable

Hormones

Phase 2,Not Applicable

Antifungal Agents

Phase 2

Immunosuppressive Agents

Phase 2,Phase 1

Antineoplastic Agents, Alkylating

Phase 2

Bendamustine Hydrochloride

Phase 2

cadexomer iodine

Phase 2,Phase 1,Not Applicable

Antibodies

Phase 2

Deoxyglucose

Phase 2

Endothelial Growth Factors

Phase 2

Fluorides

Phase 2

Fluorodeoxyglucose F18

Phase 2,Phase 1

Immunoglobulins

Phase 2

Mitogens

Phase 2

Radiopharmaceuticals

Phase 2,Phase 1

Angiogenesis Inhibitors

Phase 2,Phase 1

Angiogenesis Modulating Agents

Phase 2,Phase 1

Erlotinib Hydrochloride

Phase 2

183319-69-9

176871

Protein Kinase Inhibitors

Phase 2,Phase 1

Albumin-Bound Paclitaxel

Phase 1, Phase 2,Phase 2

Micronutrients

Phase 2,Not Applicable

Trace Elements

Phase 2,Not Applicable

Antimitotic Agents

Phase 1, Phase 2,Phase 2

Antineoplastic Agents, Phytogenic

Phase 1, Phase 2,Phase 2

Antibodies, Monoclonal

Phase 2

Cisplatin

Approved

Phase 1

15663-27-1

84093 441203 2767

Ethanol

Approved

Not Applicable

64-17-5

702

Interventional clinical trials:

(show all 45)

#	Name	Status	NCT ID	Phase	Drugs
1	Surgery and BCG in Treating Patients With Bladder Cancer	Completed	NCT00002990	Phase 3
2	Lateral Neck Sentinel Lymph Node Biopsy(LSLNB)in PTC	Completed	NCT01137097	Phase 2, Phase 3
3	Radiation Therapy or Observation Only in Treating Patients With Endometrial Cancer Who Have Undergone Surgery	Completed	NCT00002807	Phase 3
4	Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma	Completed	NCT00795782	Phase 3
5	Mitomycin C Intravesical Chemotherapy in Conjunction With Synergo® Radiofrequency-Induced Hyperthermia for Treatment of Carcinoma in Situ Non-Muscle Invasive Bladder Cancer Patients Unresponsive to Bacillus Calmette-Guérin, With or Without Papillary Tumor	Not yet recruiting	NCT03335059	Phase 3
6	RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe	Completed	NCT00688753	Phase 2	RAD001
7	RAMSETE: RAD001 in Advanced and Metastatic Silent Neuro-endocrine Tumors in Europe	Completed	NCT00688623	Phase 2	Everolimus
8	Open Trial of Bendamustine Hydrochloride in Women With Advanced Ovarian Cancer	Completed	NCT00867503	Phase 2	Bendamustine HCL
9	Selumetinib in Treating Patients With Papillary Thyroid Cancer That Did Not Respond to Radioactive Iodine	Completed	NCT00559949	Phase 2	Selumetinib
10	Aflibercept in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Did Not Respond to Radioactive Iodine Therapy	Completed	NCT00729157	Phase 2
11	pazopanib_NCRCC,Ph2 STUDY	Completed	NCT01538238	Phase 2	pazopanib
12	Sunitinib and Erlotinib in Treating Patients With Unresectable or Metastatic Kidney Cancer	Completed	NCT00425386	Phase 2	erlotinib hydrochloride;sunitinib malate
13	Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer	Completed	NCT01811212	Phase 2	Cabozantinib S-malate
14	Ridaforolimus in Treating Patients With Recurrent Metastatic and/or Locally Advanced Endometrial Cancer	Completed	NCT00770185	Phase 2	ridaforolimus
15	Proliposomal Intravesical Paclitaxel for Treatment of Low-Grade, Stage Ta, Non Muscle Invasive Bladder Cancer	Recruiting	NCT03081858	Phase 1, Phase 2	TSD-001
16	Lenvatinib and Pembrolizumab in DTC	Recruiting	NCT02973997	Phase 2	Lenvatinib
17	Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer	Recruiting	NCT02393690	Phase 2	Selumetinib
18	Trametinib in Increasing Tumoral Iodine Incorporation in Patients With Recurrent or Metastatic Thyroid Cancer	Recruiting	NCT02152995	Phase 2	Trametinib
19	Evaluation of Carboplatin/Paclitaxel With and Without Trastuzumab (Herceptin) in Uterine Serous Cancer	Active, not recruiting	NCT01367002	Phase 2	Carboplatin/Paclitaxel;Trastuzumab
20	Fludeoxyglucose F 18 PET Scan, CT Scan, and Ferumoxtran-10 MRI Scan Before Chemotherapy and Radiation Therapy in Finding Lymph Node Metastasis in Patients With Locally Advanced Cervical Cancer or High-Risk Endometrial Cancer	Active, not recruiting	NCT00416455	Phase 1, Phase 2	ferumoxtran-10
21	Cediranib Maleate With or Without Lenalidomide in Treating Patients With Thyroid Cancer	Active, not recruiting	NCT01208051	Phase 1, Phase 2	Cediranib Maleate;Lenalidomide
22	Sunitinib in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery	Active, not recruiting	NCT00381641	Phase 2	Sunitinib Malate
23	Lenvatinib and Iodine Therapy in Treating Patients With Radioactive Iodine-Sensitive Differentiated Thyroid Cancer	Not yet recruiting	NCT03506048	Phase 2	Lenvatinib
24	Toremifene in Treating Patients With Ovarian Cancer	Withdrawn	NCT00003865	Phase 2	toremifene
25	Whole-Abdominal Radiation Therapy and Cisplatin in Treating Patients With Stage III or Stage IV Endometrial Cancer That Has Been Removed by Surgery	Completed	NCT00448643	Phase 1	Cisplatin
26	Safety and PK Study of CC-90003 in Relapsed/Refractory Solid Tumors	Terminated	NCT02313012	Phase 1	CC-90003
27	Prospective Study on the Clinical Prognosis of Bilateral Central Lymph Node Dissection in the Patients With Unilateral Thyroid Papillary Carcinoma	Unknown status	NCT02648399	Not Applicable
28	Pilot 99mTechnetium-MIBI Single Photon Emission Computed Tomography - Computed Tomography (SPECT-CT) in Papillary Carcinoma (CA) Thyroid	Unknown status	NCT00984191	Not Applicable
29	Comparison Between the Axillary Bilateral-breast Approach (ABBA) and Bilateral Axillo-breast Approach (BABA) for Robotic Thyroidectomy	Unknown status	NCT02768753
30	Influence of Thyroid Hormones on the Woundhealing Process	Unknown status	NCT00929318	Not Applicable
31	Genetic Expression Alteration Affect on Lateral Neck Node Metastasis of Thyroid Papillary Microcarcinoma : Microarray Analysis	Unknown status	NCT01384669
32	Percutaneous Ethanol Injection for Primary Papillary Thyroid Microcarcinoma	Unknown status	NCT01974284	Not Applicable	percutaneous ethanol ablation
33	Testicular Function After Iodine 131 Therapy in Papillary Carcinoma Patients	Completed	NCT01150318	Not Applicable	Administration of 131 iodine
34	APPLICATION OF MOLECULAR TECHNIQUES FOR IMPROVING THE DIAGNOSIS AND TREATMENT OF NODULAR THYROID LESIONS.	Completed	NCT02323724
35	Pre-Operative Nodal Staging of Thyroid Cancer Using USPIO MRI: Preliminary Study	Completed	NCT01927887	Not Applicable	Ferumoxytol
36	Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	Completed	NCT00001668
37	Long-term Outcomes of Total Thyroidectomy Versus Less Than Total Thyroidectomy for Papillary Thyroid Microcarcinoma	Completed	NCT01648569
38	A Gene Hunting Study for Familial Papillary Thyroid Cancer	Recruiting	NCT02776969
39	Active Surveillance of Papillary Thyroid Microcarcinoma	Recruiting	NCT02609685	Not Applicable
40	Active Surveillance on Papillary Thyroid Microcarcinoma	Recruiting	NCT02938702
41	Active Surveillance of Papillary Thyroid Microcarcinoma	Recruiting	NCT02952612
42	Expression of Protein Convertases in Thyroid Nodules	Enrolling by invitation	NCT03160482
43	Endometrial Cancer and Fractalkine-receptor Axis of Fractalkine	Not yet recruiting	NCT02774395
44	A Trial Comparing USG-HIFU vs AS in Management of Low-risk PTMC	Not yet recruiting	NCT03327636	Not Applicable
45	Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma	Not yet recruiting	NCT03432299	Not Applicable

Search NIH Clinical Center for Papillary Carcinoma

Cochrane evidence based reviews: carcinoma, papillary

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Genetic Tests for Papillary Carcinoma

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Anatomical Context for Papillary Carcinoma

MalaCards organs/tissues related to Papillary Carcinoma:

⁴¹

Thyroid, Lymph Node, Breast, Kidney, Ovary, Lung, Endothelial

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Publications for Papillary Carcinoma

Articles related to Papillary Carcinoma:

(show top 50) (show all 804)

#	Title	Authors	Year
1	Coexistent cutaneous myeloid sarcoma in a patient with invasive papillary carcinoma of thyroid - A rare presentation. ( 29855456 )	Tripathy S....Baisakh M.	2018
2	Solid Papillary Carcinoma of the Breast: Magnetic Resonance Mammography, Digital Mammography, and Ultrasound Findings. ( 29613993 )	You C....Gu Y.	2018
3	Papillary carcinoma in thyroglossal duct cyst: Diagnosis by fine-needle aspiration cytology and immunocytochemistry. ( 29737627 )	Das D.K....Behbehani A.I.	2018
4	Papillary Carcinoma of Thyroid with Nasal Cavity Metastases: A Case Report. ( 29398758 )	Pourseirafi S....Faramarzi M.	2018
5	Paratesticular Serous Papillary Carcinoma of High Grade and Malignant Potential: A Rare Case with a Role for Adjuvant Therapy. ( 29662727 )	Lifton J....Boyd S.D.	2018
6	Solid papillary carcinoma with reverse polarity of the breast harbors specific morphologic, immunohistochemical and molecular profile in comparison with other benign or malignant papillary lesions of the breast: a comparative study of 9 additional cases. ( 29785016 )	Alsadoun N....Arnould L.	2018
7	Intracystic papillary carcinoma of the male breast: a case report. ( 29361955 )	Kinoshita H....Ohira M.	2018
8	Mammographic and ultrasound findings in poroid hidradenoma of the breast mimicking intraductal papilloma and papillary carcinoma: A case report. ( 29924021 )	Choi B.H....Choi N.	2018
9	Preoperative injection of carbon nanoparticles is beneficial to the patients with thyroid papillary carcinoma: From a prospective study of 102 cases. ( 29979421 )	Yan S....Zhang L.	2018
10	Expression and Distribution of Galectin-3 in Chromophobe and Papillary Carcinomas. ( 29277781 )	Cioca A....Cimpean A.M.	2018
11	AMACR Positive Papillary Renal Adenomatosis and Multifocal Papillary Carcinoma in End Stage Renal Disease. ( 29887709 )	Kansal S....Dhawan S.	2018
12	Magnetic Resonance Imaging Features of Breast Encapsulated Papillary Carcinoma. ( 29787497 )	Jiang T....Peng W.	2018
13	Encapsulated papillary carcinoma of the breast: A clinicopathological study of 49 cases. ( 29731165 )	Li X....Liu W.	2018
14	Papillary Carcinoma of Stensen's Duct with Intestinal Differentiation. ( 29774486 )	Mostafa M.E....Giorgadze T.	2018
15	Apocrine Encapsulated Papillary Carcinoma of the Breast: The First Reported Case with an Infiltrative Component. ( 29963120 )	KA9vA!ri B....Cserni G.	2018
16	LncRNA BISPR promotes the progression of thyroid papillary carcinoma by regulating miR-21-5p. ( 29856242 )	Zhang H....Jiang N.	2018
17	Early Local Recurrence in a Patient With Encapsulated Papillary Carcinoma of the Breast. ( 29803324 )	Yee C....Vesprini D.	2018
18	Acute suppurative thyroiditis caused by thyroid papillary carcinoma in the right thyroid lobe of a healthy woman. ( 29785209 )	Otani H....Sugimoto T.	2018
19	Papillary Carcinoma Thyroid Presenting as Huge Scalp Metastases. ( 29643664 )	Barwad A....Gamanagatti S.	2018
20	Transoral videolaryngoscopic surgery for papillary carcinoma arising in lingual thyroid. ( 29776698 )	Mogi C....Nibu K.I.	2018
21	Invasive Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature. ( 29950556 )	Alatsakis M....Chatzis I.	2018
22	Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation. ( 29774323 )	YA+lmaz R....A9zmen V.	2018
23	Evaluation of the presence of Epstein-Barr virus (EBV) in Iranian patients with thyroid papillary carcinoma. ( 28554750 )	Homayouni M....Amoli M.M.	2017
24	Long-term efficacy and safety of the interleukin-1 inhibitors anakinra and canakinumab in refractory BehAset disease uveitis and concomitant bladder papillary carcinoma. ( 28891187 )	Orlando I....Cantarini L.	2017
25	Associations Between Nucleus Size, and Immunohistochemical Galectin-3, Cytokeratine-19 and Hbme-1 Markers in Thyroid Papillary Carcinoma: A Morphometric Analyze. ( 29150742 )	Toy H....Sezgin Alikanoglu A.	2017
26	Anaplastic Spindle Cell Squamous Carcinoma Arising from Tall Cell Variant Papillary Carcinoma of the Thyroid Gland: A Case Report and Review of the Literature. ( 28484653 )	Patten D.K....Tolley N.	2017
27	Rosettes in papillary carcinoma of thyroid: A rare cytomorphological indicator of aggressive variants. ( 29165889 )	Nambirajan A....Jain D.	2017
28	Expression of nm23-H1 and COX-2 in thyroid papillary carcinoma and microcarcinoma. ( 28521457 )	Perisa M.M....Seiwerth S.	2017
29	Hashimoto's thyroiditis - an independent risk factor for papillary carcinoma. ( 28964693 )	Uhliarova B....Hajtman A.	2017
30	Papillary carcinoma in struma ovarii. ( 28251552 )	Carbone A....Bruno R.	2017
31	An Indian Tertiary Care Hospital Scenario of Papillary Carcinoma of Thyroid. ( 28764174 )	Karkuzhali P....Kumar M.	2017
32	18F-FDG PET/CT of Papillary Carcinoma in a Lateral Thyroglossal Duct Cyst. ( 28525461 )	Sachpekidis C....Wartenberg J.	2017
33	Solid papillary carcinoma of the breast with an associated Cytokeratin 7- negative Paget's disease of the nipple. Report of a first case. ( 29265587 )	Rupp N.J....Varga Z.	2017
34	Infiltrating Ductal Carcinoma Co-Existing with Intraductal Papillary Carcinoma of Male Breast: A Rare Case Report. ( 28764176 )	Kumar M....Javalgi A.P.	2017
35	Thyroid cancer: Overdiagnosis of papillary carcinoma - who benefits? ( 28059158 )	Brito J.P....Hay I.D.	2017
36	Molecular alterations of coexisting thyroid papillary carcinoma and anaplastic carcinoma: identification of TERT mutation as an independent risk factor for transformation. ( 28731042 )	Oishi N....Katoh R.	2017
37	Warthin-like papillary carcinoma associated with Hashimoto thyroiditis and systemic granulomatosis: a case report. ( 29512805 )	Bani M.A....Kchir N.	2017
38	Cytodiagnosis of papillary carcinoma of the male breast: Report of a case with histological correlation. ( 28469321 )	Agrawal R....Kumar P.	2017
39	A confusing lesion of thyroid papillary carcinoma. ( 29446823 )	Zehani A....Kchir N.	2017
40	Papillary Carcinoma Arising in a Thyroglossal Duct Cyst. ( 28492409 )	Higgins J.J....Horrow M.M.	2017
41	A potential role for the Hippo pathway protein, YAP, in controlling proliferation, cell cycle progression, and autophagy in BCPAP and KI thyroid papillary carcinoma cells. ( 28804541 )	Liu Z....Huang T.	2017
42	Association between the BRAF V600E mutation and ultrasound features of the thyroid in thyroid papillary carcinoma. ( 28789361 )	Li Q....Zhai Y.	2017
43	Histologic subtype needs to be considered after partial nephrectomy in patients with pathologic T1a renal cell carcinoma: papillary vs. clear cell renal cell carcinoma. ( 28451753 )	Yoo S....Kim C.S.	2017
44	Subclonal analysis in a lobular breast cancer with classical and solid growth pattern mimicking a solid-papillary carcinoma. ( 28770103 )	Christgen M....Kreipe H.	2017
45	The relationship between the expressions of tumor associated fibroblasts Cav-1 and MCT4 and the prognosis of papillary carcinoma of breast. ( 28625953 )	Zhai Y....Chen J.	2017
46	Papillary carcinoma of the thyroid in patients with primary hyperparathyroidism: Is there a link? ( 28571792 )	Beebeejaun M....Bano G.	2017
47	A Case of Thyroid Papillary Carcinoma: Remarkable Decrease in Multiple Lung Metastases within 40 Years after a Single Administration of Radioiodine without Thyroidectomy and with Later Anaplastic Transformation. ( 29279694 )	Okuyama C....Yamazaki H.	2017
48	Long-term outcome of thyroid lobectomy for unilateral multifocal papillary carcinoma. ( 28682915 )	Huang H....Wang X.	2017
49	Warthin-like variant of thyroid papillary carcinoma. ( 28923670 )	SA!nchez Fuentes P.A....RodrA-guez J.M.	2017
50	Impact of the Reclassification of the Non-Invasive Follicular Variant of Papillary Carcinoma as Benign on the Malignancy Risk of the Bethesda System for Reporting Thyroid Cytopathology: A Meta-Analysis Study. ( 28445876 )	Layfield L.J....Schmidt R.L.	2017

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Genes for Papillary Carcinoma

Genes related to Papillary Carcinoma (0 elite genes):

(show all 19)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	TG	Thyroglobulin	Protein Coding	36.44	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	10064389 10718554 17645579 (more) 1867098 7487672 11321340 17460457 19173186 8519199 9612502 7995425 19847590 19067856 11575850 15364366 15531474 8574299 11064390 15012610 15830368 16627920 1699752 10779135
2	RET	Ret Proto-Oncogene	Protein Coding	34.87	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	9315093 9635675 15203751 (more) 15368067 9516913 19543246 10389862 9466701 1987898 15502856 1381340 11953175 10027004 8740514 17191391 12574841 10597232 16940797 12162676 10923207 10566678 1823030 12608895 17718263 15982921 15753666 11117781 12743496 11061555 9162191 7585643 11927965 15805688 15119004 12499271 11329134 1569189 11720878 9192845
3	LGALS3	Galectin 3	Protein Coding	33.88	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	15500653 15487449 16722927 (more) 12370115 15233548 18809382 10357421 18795075 10821488 14585093 18581271 17001889 9072007 11402851 14575419 15924608 14870775 7677193 18415710 15529186 9703921 18540296 9679965 18198227 12207785 16178894 17017437 15173915 15947105 17728499 18652236
4	NKX2-1	NK2 Homeobox 1	Protein Coding	32.11	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	19506552 10824930 16584511 (more) 15012610 15364366 19847590 19740516 8062273 16627920 18042689
5	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	31.48	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	7609706 7756250 11321340 (more) 8554115
6	BRAF	B-Raf Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	31.4	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	14602780 14508525 19738460 (more) 20042852 15145515 16181240 15880523 16983703 17824790 18753707 19393416 19415957 17308360 15195111 20012784 16253771 15630448 16199894 16555627 12907632 18437172
7	PAX8	Paired Box 8	Protein Coding	30.85	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	15362967 16584511 18724243 (more) 10769673
8	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	29.93	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	8729520 15012610 11064390 (more) 9492154 9303357 15671779 8574299 12665646
9	TPO	Thyroid Peroxidase	Protein Coding	29.89	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	8691639 8691351 15487449 (more) 14557483 8732452 9447383 15947105 15958307 15116324 18657294 16728576 8631011 7951537 8574299 8067701 11064390 15196594 1422230
10	KRT7	Keratin 7	Protein Coding	29.81	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	12185784 16271962 11669590 (more) 9082363 10594286 19067856
11	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	28.97	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	14682475 1352125 8102129 (more) 7742498 12209722 18248390 15894362 9889797 16512896 15361207 14751194 17451461 10956383 12648572
12	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	28.54	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	17473695 11422499 7514367 (more) 9349575 18094649 7520169 14657952 11436147 8712296
13	MET	MET Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	28.38	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	9788259 14508824 11329134 (more) 11369990 10211118 9215314 11525273 14991901 15526350 9510120 12378530 14559814 19097356
14	KRT20	Keratin 20	Protein Coding	27.73	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	10594286
15	PGR	Progesterone Receptor	Protein Coding	27.36	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	16512896 8415594 12092593
16	CDH1	Cadherin 1	Protein Coding	27.1	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	11276021 8985087 7534041 (more) 12417089 12970317 18677652 14657952 12574841 16512896 12092593
17	KRT19	Keratin 19	Protein Coding	23.34	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	12708901 12446919 11038428 (more) 10843292 19213370 12207785 7520169 12743496 9428928 16178894 15947105 12162676 16224162 18833815 16000848 16722927 14870775 20198455 18308654 15958307 9099982 19956064 11669590 16627920 17728499 11534185
18	NCOA4	Nuclear Receptor Coactivator 4	Protein Coding	19.45	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	9192845 10597232
19	CLDN3	Claudin 3	Protein Coding	18.2	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	19426958 17326053

Sources

Variations for Papillary Carcinoma

Sources

Expression for Papillary Carcinoma

Search GEO for disease gene expression data for Papillary Carcinoma.

Sources

Pathways for Papillary Carcinoma

Pathways related to Papillary Carcinoma according to GeneCards Suite gene sharing:

(show all 11)

#	Super pathways	Score	Top Affiliating Genes
1	Endometrial cancer ³⁷ Show member pathways Acute myeloid leukemia ³⁷ Binding of TCF/LEF-CTNNB1 to target gene promoters ⁶⁶ Chronic myeloid leukemia ³⁷ Colorectal cancer ³⁷ Pancreatic cancer ³⁷ Prostate cancer ³⁷ Signal transduction PTEN pathway ²² Thyroid cancer ³⁷	12.54	BRAF CDH1 ERBB2 NCOA4 PAX8 RET
2	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	12.5	BRAF CDH1 ERBB2 MET PGR
3	Pathways in cancer ³⁷	12.22	BRAF CDH1 ERBB2 MET NCOA4 PAX8
4	Cytoskeletal Signaling ⁴	12.12	CDH1 CLDN3 KRT19 KRT20 KRT7 MUC1
5	MAPK Signaling: Mitogen Stimulation Pathway ⁶⁵ Show member pathways Akt Signaling Pathway ⁶⁵	11.86	BRAF ERBB2 MET
6	Bladder cancer ³⁷ ¹	11.52	BRAF CDH1 ERBB2
7	Adherens junction ³⁷	11.49	CDH1 ERBB2 MET
8	Human Thyroid Stimulating Hormone (TSH) signaling pathway ¹	11.41	BRAF PAX8 TSHR
9	Central carbon metabolism in cancer ³⁷	11.36	ERBB2 MET RET
10	a6b1 and a6b4 Integrin signaling ¹	10.92	CDH1 ERBB2 MET
11	Thyroxine (Thyroid Hormone) Production ¹	9.58	TG TPO TSHR

Sources

GO Terms for Papillary Carcinoma

Cellular components related to Papillary Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	integral component of plasma membrane	GO:0005887	9.5	CLDN3 ERBB2 MET MUC1 RET TPO
2	receptor complex	GO:0043235	8.92	ERBB2 MET RET TSHR

Biological processes related to Papillary Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	MAPK cascade	GO:0000165	9.73	BRAF ERBB2 MET RET
2	positive regulation of ERK1 and ERK2 cascade	GO:0070374	9.62	BRAF ERBB2 MET RET
3	negative regulation of signal transduction	GO:0009968	9.46	BRAF ERBB2 MET RET
4	positive regulation of kinase activity	GO:0033674	9.43	ERBB2 MET RET
5	hormone biosynthetic process	GO:0042446	9.4	TG TPO
6	entry of bacterium into host cell	GO:0035635	9.37	CDH1 MET
7	thyroid-stimulating hormone signaling pathway	GO:0038194	8.96	PAX8 TSHR
8	thyroid gland development	GO:0030878	8.92	BRAF NKX2-1 PAX8 TG

Molecular functions related to Papillary Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	identical protein binding	GO:0042802	9.8	BRAF CALCA CDH1 CLDN3 ERBB2 MET
2	transmembrane receptor protein tyrosine kinase activity	GO:0004714	9.5	ERBB2 MET RET
3	MAP kinase kinase kinase activity	GO:0004709	9.26	BRAF ERBB2 MET RET
4	thyroid-stimulating hormone receptor activity	GO:0004996	9.16	PAX8 TSHR
5	mitogen-activated protein kinase kinase binding	GO:0031434	8.92	BRAF ERBB2 MET RET

Sources

Sources for Papillary Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia