MCID: PPL021
MIFTS: 48

Papilledema

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Papilledema

MalaCards integrated aliases for Papilledema:

Name: Papilledema 12 77 54 30 56 15 74
Edema of the Optic Disc 54
Choked Disk 54

Classifications:



External Ids:

Disease Ontology 12 DOID:146
MeSH 45 D010211
NCIt 51 C3307
SNOMED-CT 69 73221001
UMLS 74 C0030353

Summaries for Papilledema

NIH Rare Diseases : 54 Papilledema is a condition in which increased pressure in or around the brain (intracranial pressure) causes swelling of the part of the optic nerve inside the eye (optic disc). Symptoms of increased intracranial pressure include headache or nausea and vomiting. Vision problems are not common initially, but may include short flickers of gray vision, blurred or double vision, and decreased field of vision or ability to see colors. Both eyes are usually affected. Papilledema by definition is caused by increased cranial pressure. Diagnosis includes a thorough eye exam by an ophthalmologist. Brain imaging studies (for example CT scan or MRI) are used to find the cause of the increased intracranial pressure. Treatment depends on the cause of the increased pressure but may include medications, surgery and/or weight management.

MalaCards based summary : Papilledema, also known as edema of the optic disc, is related to intracranial hypertension and ischemic optic neuropathy, and has symptoms including edema An important gene associated with Papilledema is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways is IL1 and megakaryocytes in obesity. The drugs Acetazolamide and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 77 Papilledema or papilloedema is optic disc swelling that is caused by increased intracranial pressure due... more...

Related Diseases for Papilledema

Diseases related to Papilledema via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 218)
# Related Disease Score Top Affiliating Genes
1 intracranial hypertension 32.7 APOH F2
2 ischemic optic neuropathy 30.5 APOH F2
3 intracranial hypertension, idiopathic 30.4 OGG1 PCLO
4 thrombophilia due to thrombin defect 30.2 APOH F2
5 cerebral sinovenous thrombosis 30.0 APOH F2
6 retinal vascular occlusion 29.9 APOH F2
7 antiphospholipid syndrome 29.6 APOH F2
8 optic papillitis 11.6
9 hydrocephalus 11.4
10 papilloma of choroid plexus 11.3
11 colloid cysts of third ventricle 11.1
12 pseudopapilledema 10.3
13 anterior cranial fossa meningioma 10.3 F2 TP53
14 thrombosis 10.3
15 spinal cord infarction 10.3 APOH F2
16 sudden sensorineural hearing loss 10.3 APOH F2
17 prothrombin deficiency, congenital 10.3 APOH F2
18 ischemic colitis 10.3 APOH F2
19 sneddon syndrome 10.3 APOH F2
20 headache 10.3
21 livedoid vasculitis 10.3 APOH F2
22 hepatic infarction 10.3 APOH F2
23 squamous cell papilloma 10.3 F2 TP53
24 thrombophlebitis 10.3 APOH F2
25 antithrombin iii deficiency 10.3 APOH F2
26 peripheral vertigo 10.3 APOH F2
27 buerger disease 10.3 APOH F2
28 central retinal vein occlusion 10.2 APOH F2
29 retinal vein occlusion 10.2 APOH F2
30 branch retinal artery occlusion 10.2 APOH F2
31 retinal artery occlusion 10.2 APOH F2
32 portal vein thrombosis 10.2 APOH F2
33 protein s deficiency 10.2 APOH F2
34 placental abruption 10.2 APOH F2
35 infective endocarditis 10.2 APOH F2
36 craniosynostosis 10.2
37 endocarditis 10.2 APOH F2
38 cholecystitis 10.2 F2 TP53
39 neuropathy 10.2
40 intermittent claudication 10.2 APOH F2
41 thrombophilia due to activated protein c resistance 10.2 APOH F2
42 barrett's adenocarcinoma 10.1 OGG1 TP53
43 budd-chiari syndrome 10.1 APOH F2
44 cataract 10.1
45 optic nerve disease 10.1
46 streptococcal meningitis 10.1 IL1R1 MYOM2
47 3-methylglutaconic aciduria, type iii 10.1
48 macular retinal edema 10.1
49 meningitis 10.1
50 mature b-cell neoplasm 10.1 MYOM2 TP53

Graphical network of the top 20 diseases related to Papilledema:



Diseases related to Papilledema

Symptoms & Phenotypes for Papilledema

UMLS symptoms related to Papilledema:


edema

GenomeRNAi Phenotypes related to Papilledema according to GeneCards Suite gene sharing:

27 (show all 27)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.81 PCLO
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.81 ARSB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.81 ARSB
4 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.81 IL1R1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-116 9.81 IL1R1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-122 9.81 ARSB F2 IL1R1 PCLO
7 Increased shRNA abundance (Z-score > 2) GR00366-A-124 9.81 IL1R1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.81 ARSB F2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-133 9.81 F2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.81 F2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.81 F2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.81 PCLO
13 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.81 PCLO
14 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.81 IL1R1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.81 F2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-183 9.81 IL1R1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.81 IL1R1
18 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.81 PCLO
19 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.81 IL1R1
20 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.81 ARSB
21 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.81 ARSB F2
22 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.81 PCLO
23 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.81 ARSB
24 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.81 IL1R1
25 Increased shRNA abundance (Z-score > 2) GR00366-A-90 9.81 PCLO
26 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.81 IL1R1
27 Increased proliferation GR00094-A 8.96 IL1R1 TP53

MGI Mouse Phenotypes related to Papilledema:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.26 ARSB IL1R1 SH3PXD2B TP53
2 mortality/aging MP:0010768 9.17 APOH F2 IL1R1 OGG1 PCLO SH3PXD2B

Drugs & Therapeutics for Papilledema

Drugs for Papilledema (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 110)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetazolamide Approved, Vet_approved Phase 4,Phase 2,Phase 3 59-66-5 1986
2
Bevacizumab Approved, Investigational Phase 4,Phase 1,Phase 2 216974-75-3
3
Ranibizumab Approved Phase 4,Phase 2 347396-82-1 459903
4
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
5
Isotretinoin Approved Phase 4 4759-48-2 5282379 5538
6
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
7
Lymecycline Approved, Investigational Phase 4 992-21-2 5280963
8 Natriuretic Agents Phase 4,Phase 2,Phase 3
9 diuretics Phase 4,Phase 2,Phase 3
10 Carbonic Anhydrase Inhibitors Phase 4,Phase 2,Phase 3
11 Anticonvulsants Phase 4,Phase 2,Phase 3
12 Angiogenesis Modulating Agents Phase 4,Phase 1,Phase 2
13 Antineoplastic Agents, Immunological Phase 4,Phase 1,Phase 2
14 Angiogenesis Inhibitors Phase 4,Phase 1,Phase 2
15 Endothelial Growth Factors Phase 4
16 Pharmaceutical Solutions Phase 4,Not Applicable
17 Mitogens Phase 4
18 Anti-Bacterial Agents Phase 4,Not Applicable
19 Anti-Infective Agents Phase 4,Phase 2
20 Dermatologic Agents Phase 4
21
Naproxen Approved, Vet_approved Phase 2, Phase 3 22204-53-1 156391 1302
22
Guaifenesin Approved, Investigational, Vet_approved Phase 2, Phase 3 93-14-1 3516
23
Aspirin Approved, Vet_approved Phase 2, Phase 3,Not Applicable 50-78-2 2244
24
Codeine Approved, Illicit Phase 2, Phase 3 76-57-3 5284371
25
Acetaminophen Approved Phase 2, Phase 3 103-90-2 1983
26
Ibuprofen Approved Phase 2, Phase 3 15687-27-1 3672
27
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 2, Phase 3 1177-87-3
28
Dexamethasone Approved, Investigational, Vet_approved Phase 2, Phase 3 50-02-2 5743
29
Warfarin Approved Phase 3 81-81-2 54678486 6691
30
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
31
Dabigatran Investigational Phase 3 211914-51-1
32 Anti-Inflammatory Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
33 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3,Phase 1
34 Hormone Antagonists Phase 2, Phase 3,Phase 1
35 Hormones Phase 2, Phase 3,Phase 1
36 glucocorticoids Phase 2, Phase 3,Phase 1
37 Antipyretics Phase 2, Phase 3
38 Chlorpheniramine, phenylpropanolamine drug combination Phase 2, Phase 3
39 Platelet Aggregation Inhibitors Phase 2, Phase 3
40 Analgesics Phase 2, Phase 3,Not Applicable
41 Fibrinolytic Agents Phase 2, Phase 3
42 Peripheral Nervous System Agents Phase 2, Phase 3,Phase 3,Not Applicable
43 Antitussive Agents Phase 2, Phase 3
44 Analgesics, Opioid Phase 2, Phase 3
45 Respiratory System Agents Phase 2, Phase 3
46 Narcotics Phase 2, Phase 3
47 Cyclooxygenase Inhibitors Phase 2, Phase 3
48 Antirheumatic Agents Phase 2, Phase 3,Phase 1,Not Applicable
49 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3,Not Applicable
50 Analgesics, Non-Narcotic Phase 2, Phase 3,Not Applicable

Interventional clinical trials:

(show all 42)
# Name Status NCT ID Phase Drugs
1 ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function Unknown status NCT00485238 Phase 4 Intravenous acetazolamide
2 Treatment of Diabetic Macular Edema (DME) With Anti-VEGF and Focal Laser Completed NCT03590444 Phase 4 Ranibizumab 0.5 MG/0.05 ML Intraocular Solution
3 Pegaptanib for Retinal Edema Secondary to Diabetic Vascular Disease(Preserve) Study Completed NCT01486238 Phase 4 Macugen® pegaptanib sodium
4 Antiacne Medications Pseudotumor Cerebri Recruiting NCT02149615 Phase 4
5 Idiopathic Intracranial Hypertension Treatment Trial Completed NCT01003639 Phase 2, Phase 3 Acetazolamide;Placebo
6 Ozurdex for Macular Edema Post Membrane Peeling Completed NCT01273727 Phase 2, Phase 3 Dexamethasone;dexamethasone
7 Surgical Idiopathic Intracranial Hypertension Treatment Trial Recruiting NCT03501966 Phase 3 Acetazolamide
8 The Efficacy and Safety of Dabigatran Etexilate for the Treatment of Cerebral Venous Thrombosis Recruiting NCT03217448 Phase 3 Dabigatran etexilate;Warfarin
9 Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo Unknown status NCT01330524 Phase 1, Phase 2 Avastin and Triamcinolone
10 Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension. Completed NCT02017444 Phase 2 AZD4017
11 Intravitreal Aflibercept Injection for Radiation Retinopathy Trial Recruiting NCT03085784 Phase 2 Aflibercept
12 Ixazomib Citrate, Lenalidomide, and Dexamethasone in Treating Patients With POEMS Syndrome Recruiting NCT02921893 Phase 2 Dexamethasone;Ixazomib Citrate;Lenalidomide
13 Efficacy of Biweekly Ranibizumab (0.5 mg) for Exudative Macular Degeneration Retinal Edema Refractory to Anti-VEGF Active, not recruiting NCT03071055 Phase 2 Ranibizumab Injection [Lucentis]
14 Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease Terminated NCT00069329 Phase 1, Phase 2 anakinra
15 Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection Terminated NCT01562132 Phase 2 Flucytosine and fluconazole;Fluconazole
16 Endovascular Stenting Treatment for Patients With Internal Jugular Vein Stenosis Not yet recruiting NCT03373292 Phase 1
17 aICP in Glaucoma and Papilledema Unknown status NCT02410148 Not Applicable
18 Ocular Point of Care Ultrasound (POCUS) to Detect Optic Disc Swelling in Comparison to Ophthalmologic Examination Unknown status NCT02992262 Not Applicable
19 OCT Imaging of Papilledema in Pediatric Idiopathic Intracranial Hypertension Unknown status NCT02665858 Not Applicable
20 Stenting of Venous Sinus Stenosis for Medically Refractory Idiopathic Intracranial Hypertension Unknown status NCT02143258 Not Applicable
21 Assessment of Retinal Nerve Fibre Layer by Optical Coherence Tomography in Uveitis Patients With Papilloedema Completed NCT01170481
22 Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine? Completed NCT00873613 Not Applicable
23 Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension Completed NCT03963336 Early Phase 1 LMWH;acetazolamide
24 Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI) Completed NCT01356134
25 Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery Completed NCT01847638 Not Applicable Prolensa (bromfenac 0.07%);Ilevro (nepafenac 0.3%)
26 Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting Completed NCT01318941 Ranibizumab
27 Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales Recruiting NCT03273179
28 Measurement of Optic Nerve Sheath Diameter in Children Without the Increased Intracranial Pressure Recruiting NCT03178760
29 Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome Recruiting NCT02896452
30 European Increlex® (Mecasermin [rDNA Origin] Injection) Growth Forum Database - IGFD Registry Recruiting NCT00903110 Increlex®
31 Venous Sinus Stenting With the River Stent in IIH Recruiting NCT03556085 Not Applicable
32 Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID / CAPS, DIRA, CANDLE, SAVI, CRMO, Still's Disease, Behcet's Disease, and Other Undifferentiated Autoinflammatory Diseases) Recruiting NCT00059748
33 Evaluating Raised Intracranial Pressure Using MR Elastography Recruiting NCT03096743 Not Applicable
34 Effectiveness of Multimodal Imaging for the Evaluation of Retinal Oedema And New vesseLs in Diabetic Retinopathy Recruiting NCT03490318
35 An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIH Active, not recruiting NCT02124486 Not Applicable
36 Validation of Non-Invasive Intracranial Pressure (ICP) Monitoring Device Active, not recruiting NCT03865576
37 Ocular Manifestations in Rheumatic Diseases Active, not recruiting NCT03753893
38 Korean Registry of Target Organ Damages in Hypertension Active, not recruiting NCT01861080
39 A Single-Center Trial of High Frequency Pegaptanib for Rapid Restoration of VEGF Levels in Diabetic Retinal Edema Available NCT01487044 Macugen (Pegaptanib Sodium)
40 Operative Procedures vs. Endovascular Neurosurgery for Untreated Pseudotumor Trial Not yet recruiting NCT02513914 Not Applicable
41 Quality and Diagnostic Utility of Mydriatic Fundus Plenoptic Photography Suspended NCT03037268
42 Disc Edema in Patients With Chronic Kidney Disease Withdrawn NCT00769834

Search NIH Clinical Center for Papilledema

Genetic Tests for Papilledema

Genetic tests related to Papilledema:

# Genetic test Affiliating Genes
1 Papilledema 30

Anatomical Context for Papilledema

MalaCards organs/tissues related to Papilledema:

42
Eye, Brain, Spinal Cord, Ovary, Bone, Kidney, Endothelial

Publications for Papilledema

Articles related to Papilledema:

(show top 50) (show all 555)
# Title Authors Year
1
Multisuture Craniosynostosis and Papilledema in Pycnodysostosis: A Paradox? ( 30394969 )
2019
2
Commentary: Idiopathic Intracranial Hypertension Without Papilledema (IIHWOP) in Chronic Refractory Headache. ( 30761073 )
2019
3
Utility of Magnetic Resonance Imaging Features for Improving the Diagnosis of Idiopathic Intracranial Hypertension Without Papilledema. ( 30829949 )
2019
4
Comment on: Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema. ( 30574942 )
2019
5
Response to comment on: Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema. ( 30574943 )
2019
6
Early Macular Vessel Density Loss in Acute Ischemic Optic Neuropathy Compared to Papilledema: Implications for Pathogenesis. ( 30637176 )
2019
7
Optic Nerve Head and Macular Optical Coherence Tomography Measurements in Papilledema Compared With Pseudopapilledema. ( 29474199 )
2019
8
Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound. ( 30538085 )
2019
9
Papilledema with Dilated Scalp Veins. ( 30577911 )
2019
10
Optical Coherence Tomography Angiography in Papilledema Compared With Pseudopapilledema. ( 30640969 )
2019
11
Bilateral Papilledema and Partially Empty Sella in a Woman in Her 30s. ( 30816946 )
2019
12
Papilledema or pseudopapilledema? ( 30900572 )
2019
13
Papilledema from gain-of-function mutations in the STAT3 gene. ( 30942636 )
2019
14
Unilateral Papilledema as the Presenting Sign of Spinal Metastases. ( 31005192 )
2019
15
Papilledema in unicoronal synostosis: a rare finding. ( 31100720 )
2019
16
Myhre syndrome with novel findings: bilateral congenital cortical cataract, bilateral papilledema, accessory nipple, and adenoid hypertrophy. ( 28562390 )
2018
17
Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient. ( 29670780 )
2018
18
Headache and Papilledema in Guillain-Barré Syndrome. ( 29374500 )
2018
19
Headache Characteristics in Children With Pseudotumor Cerebri Syndrome, Elevated Opening Pressure Without Papilledema, and Normal Opening Pressure: A Retrospective Cohort Study. ( 30137653 )
2018
20
Idiopathic Intracranial Hypertension Without Papilledema (IIHWOP) in Chronic Refractory Headache. ( 29997572 )
2018
21
Metastatic craniocervical hemangiopericytoma presenting with hydrocephalus and papilledema - Case review. ( 30318074 )
2018
22
Arteriovenous ratio and papilledema based hybrid decision support system for detection and grading of hypertensive retinopathy. ( 29249337 )
2018
23
Neuro-Behcet's disease in a case with papilledema and intracranial hypertension as the initial presentation. ( 30374484 )
2018
24
Optical coherence tomography represents a sensitive and reliable tool for routine monitoring idiopathic intracranial hypertension with and without papilledema. ( 30586220 )
2018
25
Utility of Intracranial Pressure Monitoring for Diagnosis of Idiopathic Intracranial Hypertension in the Absence of Papilledema. ( 29258930 )
2018
26
Optical coherence tomography angiography in acute unilateral nonarteritic anterior ischemic optic neuropathy: A comparison with the fellow eye and with eyes with papilledema. ( 30038161 )
2018
27
Early Macular Vessel Density Loss in Acute Ischemic Optic Neuropathy Compared to Papilledema: Implications for Pathogenesis. ( 30271677 )
2018
28
New-Onset Isolated Asymptomatic Papilledema in Two Patients Treated With Recombinant Growth Hormone. ( 28952359 )
2018
29
Five-Year-Old Boy With Behavioral Changes and Papilledema. ( 28991098 )
2018
30
Bruch's membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema. ( 29203329 )
2018
31
Commentary: The Dilemma of Papilledema in Chiari I Malformation. ( 29272471 )
2018
32
Chronic papilledema in a child with classical tuberous sclerosis. ( 29283138 )
2018
33
Re: Chang et al.: Accuracy of diagnostic imaging modalities for classifying pediatric eyes as papilledema versus pseudopapilledema (Ophthalmology. 2017;124:1839-1848). ( 29458838 )
2018
34
Bruch's membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema. ( 29535052 )
2018
35
Bruch's membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema. ( 29535053 )
2018
36
Papilledema revisiting after sinus angioplasty of chronic cerebral venous sinus thrombosis. ( 29676328 )
2018
37
Young Man With Severe Bilateral Papilledema. ( 29800986 )
2018
38
Papilledema: Point-of-Care Ultrasound Diagnosis in the Emergency Department. ( 29849246 )
2018
39
Rapid effect of depletive lumbar puncture on papilledema in intracranial hypertension. ( 29903588 )
2018
40
Papilledema in Idiopathic Intracranial Hypertension. ( 29399792 )
2018
41
The Translaminar Pressure Gradient: Papilledema After Trabeculectomy Treated With Optic Nerve Sheath Fenestration. ( 29979338 )
2018
42
Re: Chang et al.: Accuracy of diagnostic imaging modalities for classifying pediatric eyes as papilledema versus pseudopapilledema (Ophthalmology. 2017;124:1839-1848). ( 30143102 )
2018
43
Pediatric Papilledema: Review and a Clinical Care Algorithm. ( 30239361 )
2018
44
Masking of Papilledema by Glaucoma. ( 30532370 )
2018
45
Re: Re: The Translaminar Pressure Gradient: Papilledema after Trabeculectomy Treated with Optic Nerve Sheath Fenestration. ( 30540674 )
2018
46
Re: Radke et al - The Translaminar Pressure Gradient - Papilledema After Trabeculectomy Treated With Optic Nerve Sheath Fenestration. ( 30540675 )
2018
47
Adduction-Induced Deformations Evoke Peripapillary Folds in Papilledema. ( 30590078 )
2018
48
Vestibular Schwannoma Presenting with Bilateral Papilledema Without Hydrocephalus: Case Study. ( 29375948 )
2017
49
Papilledema in children with hydrocephalus: incidence and associated factors. ( 28387641 )
2017
50
Hypoparathyroidism Should Always Be Checked in Papilledema. ( 28694607 )
2017

Variations for Papilledema

Expression for Papilledema

Search GEO for disease gene expression data for Papilledema.

Pathways for Papilledema

Pathways related to Papilledema according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.02 F2 IL1R1

GO Terms for Papilledema

Biological processes related to Papilledema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleotide-excision repair GO:0006289 9.4 OGG1 TP53
2 base-excision repair GO:0006284 9.37 OGG1 TP53
3 positive regulation of reactive oxygen species metabolic process GO:2000379 9.32 F2 TP53
4 blood coagulation, intrinsic pathway GO:0007597 9.26 APOH F2
5 positive regulation of blood coagulation GO:0030194 9.16 APOH F2
6 regulation of blood coagulation GO:0030193 8.96 APOH F2
7 negative regulation of fibrinolysis GO:0051918 8.62 APOH F2

Sources for Papilledema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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