CARP
MCID: PPL052
MIFTS: 31

Papillomatosis, Confluent and Reticulated (CARP)

Categories: Genetic diseases, Skin diseases
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Aliases & Classifications for Papillomatosis, Confluent and Reticulated

MalaCards integrated aliases for Papillomatosis, Confluent and Reticulated:

Name: Papillomatosis, Confluent and Reticulated 57
Papillomatosis, Reticulated and Confluent, of Gougerot and Carteaud 57
Confluent and Reticulated Papillomatosis 75
Papillomatosis, Familial Cutaneous 57
Carp 57

Characteristics:


Inheritance:

Autosomal dominant 57

OMIM®:

57 (Updated 08-Dec-2022)
Miscellaneous:
onset in teenage or young adult years
mode of inheritance is unclear
favorable response to treatment with minocycline or azithromycin


Classifications:



External Ids:

OMIM® 57 167900
MedGen 40 C0263385
SNOMED-CT via HPO 69 26996000 396228006 399955009

Summaries for Papillomatosis, Confluent and Reticulated

OMIM®: 57 Confluent and reticulated papillomatosis is a dermatologic disorder characterized by onset in the teenage or young adult years of hyperkeratotic 1- to 2-mm papules that increase in size to 4 to 5 mm and coalesce to form a reticular pattern peripherally and a confluent pattern centrally. Early papules can be erythematous and later turn brown. Affected individuals are usually otherwise asymptomatic. The condition is distinct from acanthosis nigricans and tinea versicolor (infection with the yeast Pityrosporum), but can appear similar. Microscopic examination of skin biopsy shows epidermal undulation with hyperkeratosis, squat papillomatosis, and occasional acanthotic downward projections from the bases of the dells between papillomatous areas. Antibacterial agents such as minocycline and azithromycin are effective, perhaps due to their antiinflammatory and immunomodulatory properties (summary by Scheinfeld, 2006). (167900) (Updated 08-Dec-2022)

MalaCards based summary: Papillomatosis, Confluent and Reticulated, also known as papillomatosis, reticulated and confluent, of gougerot and carteaud, is related to collins pope syndrome and edinburgh malformation syndrome. Affiliated tissues include skin, retina and kidney, and related phenotype is hyperkeratosis.

Wikipedia: 75 Confluent and reticulated papillomatosis of Gougerot and Carteaud is an uncommon but distinctive... more...

Related Diseases for Papillomatosis, Confluent and Reticulated

Diseases related to Papillomatosis, Confluent and Reticulated via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 401)
# Related Disease Score Top Affiliating Genes
1 collins pope syndrome 11.2
2 edinburgh malformation syndrome 11.1
3 acromelic frontonasal dysostosis 11.1
4 kleefstra syndrome 1 11.1
5 carp allergy 11.0
6 cornelia de lange syndrome 1 10.9
7 jacobsen syndrome 10.9
8 german syndrome 10.9
9 hadziselimovic syndrome 10.9
10 acanthosis nigricans 10.8
11 hemorrhagic disease 10.7
12 triploidy 10.6
13 pityriasis versicolor 10.6
14 exanthem 10.6
15 polyploidy 10.6
16 viral infectious disease 10.5
17 polycystic ovary syndrome 10.5
18 dermatophytosis 10.5
19 type 2 diabetes mellitus 10.5
20 myxozoa 10.5
21 common cold 10.4
22 acne 10.4
23 b-cell lymphoma 10.3
24 henoch-schoenlein purpura 10.3
25 toxic encephalopathy 10.3
26 leptin deficiency or dysfunction 10.3
27 cytokine deficiency 10.3
28 hyperlipoproteinemia, type i 10.3
29 insulin-like growth factor i 10.3
30 down syndrome 10.2
31 hypoascorbemia 10.2
32 48,xyyy 10.2
33 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.2
34 acute kidney failure 10.2
35 darier-white disease 10.2
36 photoparoxysmal response 1 10.2
37 erythrokeratodermia variabilis et progressiva 1 10.2
38 ige responsiveness, atopic 10.2
39 pseudoatrophoderma colli 10.2
40 polycystic ovary syndrome 1 10.2
41 epidermodysplasia verruciformis 1 10.2
42 anhidrosis 10.2
43 prediabetes syndrome 10.2
44 hyperinsulinism 10.2
45 syringoma 10.2
46 papilloma 10.2
47 palmoplantar keratosis 10.2
48 acquired immunodeficiency syndrome 10.2
49 primary localized amyloidosis 10.2
50 rheumatoid arthritis 10.2

Graphical network of the top 20 diseases related to Papillomatosis, Confluent and Reticulated:



Diseases related to Papillomatosis, Confluent and Reticulated

Symptoms & Phenotypes for Papillomatosis, Confluent and Reticulated

Human phenotypes related to Papillomatosis, Confluent and Reticulated:

30
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hyperkeratosis 30 HP:0000962

Symptoms via clinical synopsis from OMIM®:

57 (Updated 08-Dec-2022)
Skin Nails Hair Skin Histology:
hyperkeratosis
epidermal undulation
squat papillomatosis
acanthotic downward projections from areas between the papillae

Skin Nails Hair Skin Electron Microscopy:
increased number of transitional cells between the stratum granulosum and stratum corneum

Skin Nails Hair Skin:
papillomatosis, reticular on the periphery, 1 to 2-mm growing to 4-5-mm and coalescing
papillomatosis, confluent centrally, erythematous turning brown later
scaly rash

Clinical features from OMIM®:

167900 (Updated 08-Dec-2022)

Drugs & Therapeutics for Papillomatosis, Confluent and Reticulated

Search Clinical Trials, NIH Clinical Center for Papillomatosis, Confluent and Reticulated

Genetic Tests for Papillomatosis, Confluent and Reticulated

Anatomical Context for Papillomatosis, Confluent and Reticulated

Organs/tissues related to Papillomatosis, Confluent and Reticulated:

MalaCards : Skin, Retina, Kidney, Liver, Skeletal Muscle, Pituitary, Olfactory Bulb

Publications for Papillomatosis, Confluent and Reticulated

Articles related to Papillomatosis, Confluent and Reticulated:

(show top 50) (show all 11709)
# Title Authors PMID Year
1
[Two brothers with brown, reticulate hyperpigmentations. Papillomatosis confluens et reticularis (Gougerot-Carteaud): familial occurrence and response to azithromycin]. 57
16827916 2006
2
Recurrent confluent and reticulate papillomatosis of Gougerot and Carteaud in siblings. 57
12780727 2003
3
Familial confluent and reticulated papillomatosis. 57
11843664 2002
4
Familial occurrence of confluent and reticulated papillomatosis. 57
7316560 1981
5
Familial cutaneous papillomatosis. 57
5835327 1965
6
Mechanisms of fish protein degradation caused by grass carp spoilage bacteria: A bottom-up exploration from the molecular level, muscle microstructure level, to related quality changes. 62
36191413 2023
7
Generation of novel antioxidant peptides from silver carp muscle hydrolysate: Gastrointestinal digestion stability and transepithelial absorption property. 62
36194932 2023
8
The influence of pH and monovalent/divalent cations on the structural and physicochemical properties of myofibrillar protein from silver carp. 62
36252377 2023
9
Silver carp (Hypophthalmichthys molitrix) by-product hydrolysates: A new nitrogen source for Bifidobacterium animalis ssp. lactis BB-12. 62
36444081 2023
10
The protective pattern of chitosan-based active coating on texture stabilization of refrigerated carp fillets from the perspective of proteolysis. 62
36444025 2023
11
The interaction study of soluble pectin fiber and surimi protein network from silver carp (Hypophthalmichthys molitrix) based on a new prediction model. 62
36358075 2023
12
Screening and characterization of a novel antifreeze peptide from silver carp muscle hydrolysate. 62
36358085 2023
13
Simultaneous effect of high intensity ultrasound power, time, and salt contents on gelling properties of silver carp surimi. 62
36358084 2023
14
Corrigendum to: "Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation" [Carbohydr. Polym. 297 (2022) 120048]. 62
36446516 2023
15
Hematological changes, redox imbalance, and changes in Na+/K+-ATPase activity caused by bisphenol-A and the integrated biomarker responses in Labeo rohita (Hamilton, 1822). 62
36461564 2023
16
Incorporation of curcumin extract with lemongrass essential oil into the middle layer of triple-layered films based on furcellaran/chitosan/gelatin hydrolysates - In vitro and in vivo studies on active and intelligent properties. 62
36303367 2023
17
Novel intelligent films containing anthocyanin and phycocyanin for nondestructively tracing fish spoilage. 62
36130433 2023
18
ROS/ER stress contributes to trimethyltin chloride-mediated hepatotoxicity; Tea polyphenols alleviate apoptosis and immunosuppression. 62
36370998 2023
19
Highly TVB-N sensitive film with CMS as the 'bridge' via electrostatic interaction and hydrogen bond self-assembly for monitoring food freshness in intelligent packaging. 62
36055076 2023
20
Potential biomarker of phenol toxicity in freshwater fish C. mrigala: Serum cortisol, enzyme acetylcholine esterase and survival organ gill. 62
36283648 2023
21
Nutrient cycling enhancement in intensive-extensive aquaculture through C/N ratio manipulation and periphyton support. 62
36370938 2023
22
Spatial ecology of non-native common carp (Cyprinus carpio) in Lake Ontario with implications for management. 62
36474645 2023
23
Evaluation of metabolic stress status in common carp (Cyprinus carpio) exposed to the fungicide folpet. 62
36283647 2023
24
Acute deltamethrin exposure induces oxidative stress, triggers endoplasmic reticulum stress, and impairs hypoxic resistance of crucian carp. 62
36368507 2023
25
Development and characterization of active packaging nanofiber mats based on gelatin‑sodium alginate containing probiotic microorganisms to improve the shelf-life and safety quality of silver carp fillets. 62
36341755 2023
26
Research on apoptotic mechanism and related pathways involved in postmortem grass carp (Ctenopharyngodon idellus) muscle. 62
35861049 2023
27
Dietary cinnamaldehyde improves muscle protein content by promoting muscle fiber growth via PTP1B/IGF1/PI3K/AKTs-TOR/FOXO3a signaling pathway in grass carp (Ctenopharyngodon idella). 62
35998490 2023
28
Gut microbiota and metabolic profile as affected by Maillard reaction products derived from bighead carp meat hydrolysates with galactose and galacto-oligosaccharides during in vitro pig fecal fermentation. 62
35969991 2023
29
Adverse effects of polystyrene microplastics in the freshwater commercial fish, grass carp (Ctenopharyngodon idella): Emphasis on physiological response and intestinal microbiome. 62
36208741 2023
30
Effect of multifactorial free and liposome-coated of bay laurel (Laurus nobilis) and rosemary (Salvia rosmarinus) extracts on the behavior of Listeria monocytogenes and Vibrio parahaemolyticus in silver carp (Hypophthalmichthys molitrix) stored at 4 °C. 62
36206926 2023
31
Molecular cloning, tissue distribution, and pharmacologic function of melanocortin-3 receptor in common carp (Cyprinus carpio). 62
36336108 2023
32
COVID-19's effect on the spatial integration of fish markets: Evidence from carp price in China. 62
36345505 2023
33
Ca2+ATPase enzyme activities and lipid and protein oxidations of grass carp (Ctenopharyngodon idellus) stored at 4 °C for 30 min under electromagnetic fields. 62
36029673 2023
34
Amino acid degradation and related quality changes caused by common spoilage bacteria in chill-stored grass carp (Ctenopharyngodon idella). 62
36041337 2023
35
Effects of the synthetic progestin levonorgestrel on some aspects of thyroid physiology in common carp (Cyprinus carpio). 62
36244424 2023
36
Traceability and identification of fish gelatin from seven cyprinid fishes by high performance liquid chromatography and high-resolution mass spectrometry. 62
36084584 2023
37
miR-2188-5p promotes GCRV replication by the targeted degradation of klf2a in Ctenopharyngodon idellus. 62
36084755 2023
38
Mechanism of evodiamine blocking Nrf2/MAPK pathway to inhibit apoptosis of grass carp hepatocytes induced by DEHP. 62
36368504 2023
39
The antipsychotic drug olanzapine altered lipid metabolism in the common carp (Cyprinus carpio L.): Insight from the gut microbiota-SCFAs-liver axis. 62
36170916 2023
40
Functional analysis of ascP in Aeromonas veronii TH0426 reveals a key role in the regulation of virulence. 62
36355279 2022
41
Physicochemical properties of iodine and selenium biofortified Sparus aurata and Cyprinus carpio during frozen storage. 62
35917781 2022
42
Assessment of Some Heavy Metals and Their Relationship with Oxidative Stress and Immunological Parameters in Aquatic Animal Species. 62
36459341 2022
43
Expression analysis of Igs and mucosal immune responses upon SVCV infection in common carp (Cyprinus carpio L.). 62
36419606 2022
44
Genome-Wide Association Study Reveals SNPs and Candidate Genes Related to Growth and Body Shape in Bighead Carp (Hypophthalmichthys nobilis). 62
36350467 2022
45
Proteomics-based molecular and functional characteristic profiling of muscle tissue in Triploid crucian carp. 62
36349986 2022
46
Effects of actomyosin dissociation on the physicochemical and gelling properties of silver carp myofibrillar protein sol during freeze-thaw cycles. 62
36461392 2022
47
Health risk assessment of heavy metals (Zn, Pb, Cd, and Hg) in water and muscle tissue of farmed carp species in North Iran. 62
36462077 2022
48
Effects of Zinc Adaptation on Histological Morphology, Antioxidant Responses, and Expression of Immune-Related Genes of Grass Carp (Ctenopharyngodon idella). 62
35015244 2022
49
Chitosan/bacterial cellulose films incorporated with tea polyphenol nanoliposomes for silver carp preservation. 62
36184184 2022
50
Dactylogyrus extensus and Pseudomonas fluorescens dual infection in farmed common carp (Cyprinuscarpio). 62
36334863 2022

Variations for Papillomatosis, Confluent and Reticulated

Expression for Papillomatosis, Confluent and Reticulated

Search GEO for disease gene expression data for Papillomatosis, Confluent and Reticulated.

Pathways for Papillomatosis, Confluent and Reticulated

GO Terms for Papillomatosis, Confluent and Reticulated

Sources for Papillomatosis, Confluent and Reticulated

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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