MCID: PRC011
MIFTS: 28

Parachordoma

Categories: Cancer diseases

Aliases & Classifications for Parachordoma

MalaCards integrated aliases for Parachordoma:

Name: Parachordoma 12 15 17 70

Classifications:



External Ids:

Disease Ontology 12 DOID:2647
NCIt 50 C6581
SNOMED-CT 67 404086000
UMLS 70 C1266175

Summaries for Parachordoma

MalaCards based summary : Parachordoma is related to rare tumor and chondrosarcoma. An important gene associated with Parachordoma is KRT7 (Keratin 7), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include brain, kidney and skin, and related phenotype is muscle.

Related Diseases for Parachordoma

Diseases related to Parachordoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 298)
# Related Disease Score Top Affiliating Genes
1 rare tumor 30.5 DES ACTC1
2 chondrosarcoma 30.5 VIM S100A1 MUC1
3 cellular ependymoma 29.9 VIM MUC1 GFAP
4 myxopapillary ependymoma 29.9 VIM MUC1 GFAP
5 myoepithelioma 29.7 VIM S100A1 MUC1 GFAP ACTC1
6 chordoma 29.5 VIM S100A1 MUC1 KRT7 GFAP DES
7 chondromyxoid fibroma 29.5 VIM S100A1 DES ACTC1
8 fibroma 29.5 VIM S100A1 DES ACTC1
9 sarcoma, synovial 29.4 VIM MUC1 KRT7 DES
10 ossifying fibromyxoid tumor 29.2 VIM S100A1 MUC1 DES ACTC1
11 spindle cell sarcoma 29.2 VIM MUC1 KRT7 DES ACTC1
12 syringoma 28.6 VIM S100A1 MUC1 KRT7 GFAP DES
13 myoepithelial carcinoma 28.6 ZNF444 VIM MUC1 KRT7 GFAP ACTC1
14 chest wall parachordoma 11.2
15 lymphangiectasis 10.3 VIM ACTC1
16 nodular hidradenoma 10.3 VIM MUC1
17 endometrial mucinous adenocarcinoma 10.3 VIM MUC1
18 intravascular papillary endothelial hyperplasia 10.3 VIM ACTC1
19 glomangiomyoma 10.3 VIM ACTC1
20 spindle cell thymoma 10.3 MUC1 DES
21 fibroblastic rheumatism 10.3 DES ACTC1
22 ovarian fibrothecoma 10.3 DES ACTC1
23 myxoid chondrosarcoma 10.2
24 adult cystic nephroma 10.2 DES ACTC1
25 infantile digital fibromatosis 10.2 VIM DES
26 pulmonary vein stenosis 10.2 DES ACTC1
27 plasmablastic lymphoma 10.2 MUC1 DES
28 lymphangiomatosis 10.2 VIM DES
29 botryoid rhabdomyosarcoma 10.2 DES ACTC1
30 congenital epulis 10.2 VIM DES
31 epulis 10.2 VIM DES
32 fibrous meningioma 10.2 VIM MUC1
33 intraneural perineurioma 10.2 S100A1 MUC1
34 rare soft tissue tumor 10.2
35 scrotum paget's disease 10.2 MUC1 KRT7
36 gallbladder signet ring cell adenocarcinoma 10.2 MUC1 KRT7
37 osteofibrous dysplasia 10.2 VIM MUC1
38 non-langerhans-cell histiocytosis 10.2 DES ACTC1
39 pancreatic foamy gland adenocarcinoma 10.2 MUC1 KRT7
40 ovarian small cell carcinoma 10.2 MUC1 DES
41 myofibroma 10.2 S100A1 DES
42 urinary bladder villous adenoma 10.2 MUC1 KRT7
43 embryonal sarcoma 10.2 VIM DES
44 villous adenoma 10.2 MUC1 KRT7
45 proximal spinal muscular atrophy 10.2 MUC1 DES
46 mucinous intrahepatic cholangiocarcinoma 10.2 MUC1 KRT7
47 bile duct cystadenocarcinoma 10.2 MUC1 KRT7
48 acral lentiginous melanoma 10.2 VIM MUC1
49 colonic lymphangioma 10.2 MUC1 KRT7
50 biliary papillomatosis 10.2 MUC1 KRT7

Graphical network of the top 20 diseases related to Parachordoma:



Diseases related to Parachordoma

Symptoms & Phenotypes for Parachordoma

MGI Mouse Phenotypes related to Parachordoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.1 ACTC1 CHGA DES GFAP S100A1 VIM

Drugs & Therapeutics for Parachordoma

Search Clinical Trials , NIH Clinical Center for Parachordoma

Genetic Tests for Parachordoma

Anatomical Context for Parachordoma

MalaCards organs/tissues related to Parachordoma:

40
Brain, Kidney, Skin, Trachea

Publications for Parachordoma

Articles related to Parachordoma:

(show top 50) (show all 77)
# Title Authors PMID Year
1
Skull Base Parachordoma/Myoepithelioma. 61
32147599 2020
2
Primary parachordoma in the trachea: An unusual cause of dyspnoea. 61
31571637 2019
3
Recurrent parachordoma of the lower back: A case report. 61
30386446 2019
4
Erratum: Adrenal collision tumor (parachordoma and ganglioneuroma): A case report. 61
30101030 2018
5
Adrenal collision tumor (parachordoma and ganglioneuroma): A case report. 61
29844903 2018
6
Myoepithelial tumor of soft tissue and bone: A current perspective. 61
28145559 2017
7
Programmed Death Ligand 1 (PD-L1) Expression in Malignant Mesenchymal Tumors. 61
28832074 2017
8
Chordoma Cutis - A Diagnosis not to be Missed. 61
25120995 2014
9
[Current surgical treatment of primary chest wall tumor]. 61
24743406 2014
10
Parachordoma/myoepithelioma of the kidney: first report of a myxoid mimicry in an unusual location. 61
24696746 2014
11
Primary intracranial Parachordoma: An unusual tumor in brain. 61
25525557 2014
12
Recurrent skeletal extra-axial chordoma confirmed with brachyury: imaging features and review of the literature. 61
23653219 2013
13
A case of parachordoma on the chest wall and literature review. 61
24135242 2013
14
Soft tissue chordomas: a clinicopathologic analysis of 11 cases. 61
23588366 2013
15
Parachordoma/myoepithelioma. 61
22618759 2013
16
Parachordoma of soft tissues of the arm: a very rare tumour. 61
24083043 2013
17
Histopathological, immunohistochemical and molecular spectrum of myoepithelial tumours of soft tissues. 61
23097005 2012
18
Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis. 61
23372917 2012
19
Myxoid chondrosarcoma of sphenoid bone. 61
23189013 2012
20
Clinical and radiological presentations of pelvic parachordoma. 61
22532921 2012
21
Primary intraosseous myoepithelioma arising in the iliac bone and displaying trisomies of 11, 15, 17 with del (16q) and del (22q11)--A rare case report with review of literature. 61
22054860 2011
22
Presacral parachordoma causing intestinal obstruction in a patient with renal failure: Report of a case. 61
21922364 2011
23
Axial chordoma and parachordoma (soft tissue chordoma): two of a kind: report of two cases with primary diagnosis on fine-needle cytology samples. 61
20730897 2011
24
Intraneural parachordoma of the arm with regional metastases. 61
21499979 2011
25
On being a pathologist: Maria DÄ…bska--the woman behind the eponym, a pioneer in pathology. 61
21683864 2011
26
Parachordoma: a recurrent case and review of the literature. 61
21630208 2011
27
Extra-axial soft tissue chordoma of wrist. 61
21397407 2011
28
Biological materials for diaphragmatic repair: initial experiences with the PeriGuard Repair Patch®. 61
21243571 2011
29
Parachordoma of skull. 61
20303594 2010
30
Fine needle aspiration appearance of parachordoma. 61
20306999 2010
31
Parachordoma: a very rare tumour of the hand. 61
20067931 2009
32
Possible parachordoma in a dog. 61
19802045 2009
33
Pulmonary metastases from parachordoma. 61
19632372 2009
34
Metastatic parachordoma. 61
19208078 2009
35
Heterogeneous genetic profiles in soft tissue myoepitheliomas. 61
18604193 2008
36
Case report: parachordoma of soft tissues of the arm. 61
18219545 2008
37
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. 61
18301055 2008
38
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. 61
17652546 2007
39
Parachordoma or myoepithelion?: a case report of a rare soft tissue tumor. 61
17295651 2007
40
[Parachordoma of elbow: report of a case]. 61
17493397 2007
41
Fatal parachordoma. 61
17260126 2007
42
Extra-axial chordoma. 61
17149966 2006
43
Extra-axial chordoma. 61
16943479 2006
44
Retroperitoneal parachordoma in a patient with a history of recurrent pain. 61
15863385 2005
45
Parachordoma is not distinguishable from axial chordoma using immunohistochemistry. 61
15086843 2004
46
Parachordoma or chordoma periphericum? Case report of a tumor of the thoracic wall. 61
12827710 2003
47
Parachordoma of tibia--a case report. 61
15025303 2003
48
Parachordoma with multiple metastases. 61
12886158 2003
49
[Soft tissue myoepithelioma, a rare tumor. A case report]. 61
12743501 2003
50
Radiographic, computed tomographic and histopathologic appearance of a presumed spinal chordoma in a dog. 61
12174996 2002

Variations for Parachordoma

Expression for Parachordoma

Search GEO for disease gene expression data for Parachordoma.

Pathways for Parachordoma

Pathways related to Parachordoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.51 VIM MUC1 KRT7 DES ACTC1
2
Show member pathways
11.29 VIM KRT7 GFAP DES
3 11.19 VIM DES ACTC1
4
Show member pathways
10.91 VIM DES

GO Terms for Parachordoma

Cellular components related to Parachordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 9.13 VIM GFAP DES
2 intermediate filament GO:0005882 8.92 VIM KRT7 GFAP DES

Biological processes related to Parachordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of heart contraction GO:0008016 9.37 S100A1 DES
2 astrocyte development GO:0014002 9.32 VIM GFAP
3 Bergmann glial cell differentiation GO:0060020 9.26 VIM GFAP
4 intermediate filament-based process GO:0045103 9.16 VIM GFAP
5 muscle filament sliding GO:0030049 9.13 VIM DES ACTC1
6 intermediate filament organization GO:0045109 8.8 VIM GFAP DES

Molecular functions related to Parachordoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 VIM GFAP DES

Sources for Parachordoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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