MCID: PRG008
MIFTS: 41

Paragonimiasis

Categories: Rare diseases, Infectious diseases, Respiratory diseases

Aliases & Classifications for Paragonimiasis

MalaCards integrated aliases for Paragonimiasis:

Name: Paragonimiasis 12 53 55 3 44 15 73
Paragonimus Westermani Infection 53
Infection by Paragonimus 12
Pulmonary Paragonimiasis 12
Lung Fluke Infection 12
Lung Fluke Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10699
ICD10 33 B66.4
ICD9CM 35 121.2
MeSH 44 D010237
NCIt 50 C84995
UMLS 73 C0030424

Summaries for Paragonimiasis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection by flukes of the genus Paragonimus. In the acute phase, the symptoms are diarrhea, abdominal pain, fever, cough, urticaria, hepatosplenomegaly, pulmonary abnormalities, and eosinophilia. Pulmonary manifestations include cough, expectoration of discolored sputum, hemoptysis, and chest radiographic abnormalities. Various organs like brain, spleen and liver can be infected.

MalaCards based summary : Paragonimiasis, also known as paragonimus westermani infection, is related to strongyloidiasis and schistosomiasis. An important gene associated with Paragonimiasis is IL5 (Interleukin 5), and among its related pathways/superpathways are PAK Pathway and IL-17 Family Signaling Pathways. Affiliated tissues include lung, liver and brain.

CDC : 3 Paragonimus is a lung fluke (flatworm) that infects the lungs of humans after eating an infected raw or undercooked crab or crayfish. Less frequent, but more serious cases of paragonimiasis occur when the parasite travels to the central nervous system.

Wikipedia : 76 Paragonimiasis is a food-borne parasitic infection caused by the lung fluke, most commonly Paragonimus... more...

Related Diseases for Paragonimiasis

Diseases related to Paragonimiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 strongyloidiasis 30.1 IL13 IL5
2 schistosomiasis 29.9 IL13 IL5 RNASE3
3 eosinophilic pneumonia 29.0 CCL17 IL13 IL5 RNASE3
4 necatoriasis 10.5 CCL17 IL5
5 cerebritis 10.5
6 loeffler endocarditis 10.5 IL5 RNASE3
7 cough variant asthma 10.5 IL5 RNASE3
8 cow milk allergy 10.5 IL5 RNASE3
9 intrinsic asthma 10.5 IL5 RNASE3
10 atopic keratoconjunctivitis 10.5 IL5 RNASE3
11 eosinophilic gastroenteritis 10.5 IL5 RNASE3
12 gastrointestinal allergy 10.4 IL5 RNASE3
13 cytokine deficiency 10.4 IL13 IL5
14 status asthmaticus 10.4 IL5 RNASE3
15 angioimmunoblastic lymphadenopathy with dysproteinemia 10.4 IL13 IL5
16 kimura disease 10.4 IL5 RNASE3
17 respiratory syncytial virus infectious disease 10.4 IL13 IL5
18 cellulitis 10.4 IL5 RNASE3
19 angiostrongyliasis 10.4 IL13 IL5
20 sinusitis 10.4 IL5 RNASE3
21 allergic bronchopulmonary aspergillosis 10.4 CCL17 IL5
22 ascaris lumbricoides infection 10.4 IL13 IL5
23 eosinophilic meningitis 10.4 IL13 IL5
24 intestinal schistosomiasis 10.4 IL13 IL5
25 eosinophilic gastritis 10.4 IL13 IL5
26 chronic tic disorder 10.3 IL13 IL5
27 milk allergy 10.3 IL5 RNASE3
28 esophagitis, eosinophilic, 1 10.3 IL13 IL5
29 wells syndrome 10.3 IL5 RNASE3
30 enterobiasis 10.2 IL13 IL5
31 esophageal disease 10.2 IL13 IL5
32 hepatitis 10.2
33 paranasal sinus disease 10.2 IL13 IL5
34 gastroenteritis 10.2 IL5 RNASE3
35 aspergillosis 10.2 CCL17 IL5
36 mast cell disease 10.2 IL13 IL5
37 radiculopathy 10.2 CXCR3 IL5
38 pustulosis palmaris et plantaris 10.2 CXCR3 IL5
39 clonorchiasis 10.1
40 esophagitis 10.1 IL13 IL5
41 erythema multiforme 10.1 CCL17 CXCR3
42 cutaneous leishmaniasis 10.1 IL13 IL5
43 churg-strauss syndrome 10.1 CCL17 IL5 RNASE3
44 chronic meningitis 10.1 IL5 MT-CO1
45 bronchitis 10.0 IL5 RNASE3
46 bullous pemphigoid 10.0 CCL17 IL5 RNASE3
47 nonspecific interstitial pneumonia 10.0 CXCR3 IL13
48 hypersensitivity reaction disease 10.0 IL13 IL5
49 cercarial dermatitis 10.0 IL5 MT-CO1
50 apple allergy 10.0 CCL17 IL13 IL5

Graphical network of the top 20 diseases related to Paragonimiasis:



Diseases related to Paragonimiasis

Symptoms & Phenotypes for Paragonimiasis

Drugs & Therapeutics for Paragonimiasis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Parasitic Infections of the Gastrointestinal Tract Terminated NCT00001162

Search NIH Clinical Center for Paragonimiasis

Cochrane evidence based reviews: paragonimiasis

Genetic Tests for Paragonimiasis

Anatomical Context for Paragonimiasis

MalaCards organs/tissues related to Paragonimiasis:

41
Lung, Liver, Brain, Spleen, Testes, Skin, Colon

Publications for Paragonimiasis

Articles related to Paragonimiasis:

(show top 50) (show all 449)
# Title Authors Year
1
Hepatic Paragonimiasis Mimicking Hepatocellular Carcinoma. ( 29340921 )
2018
2
Scrotal Paragonimiasis in adults: Two case reports and review of literature. ( 29620658 )
2018
3
ELISA based on a recombinant Paragonimus heterotremus protein for serodiagnosis of human paragonimiasis in Thailand. ( 29843786 )
2018
4
Clonorchiasis or Paragonimiasis? ( 29483404 )
2018
5
Reply to "Clonorchiasis or Paragonimiasis?" ( 29483405 )
2018
6
Electrocardiogram in a patient with Paragonimiasis westermani-triggered Takotsubo syndrome. ( 29772959 )
2018
7
Hemorrhagic intraspinal paragonimiasis. ( 29378919 )
2018
8
Examining human paragonimiasis as a differential diagnosis to tuberculosis in The Gambia. ( 29334998 )
2018
9
Unresolving Pneumonia with Pleural effusion: Pulmonary Paragonimiasis. ( 28746328 )
2017
10
Severe Pleuropulmonary Paragonimiasis Caused by Paragonimus mexicanus Treated as Tuberculosis in Ecuador. ( 27879464 )
2017
11
Distinct MDCT imaging features to differential diagnosis of hepatic paragonimiasis and small hepatocellular carcinoma. ( 28418840 )
2017
12
A Case of Ectopic Paragonimiasis in a 17th Century Korean Mummy. ( 28395568 )
2017
13
Hepatic paragonimiasis: a single-center retrospective analysis of 32 cases in Mainland China. ( 29230298 )
2017
14
Takotsubo cardiomyopathy associated with Paragonimiasis westermani. ( 28884631 )
2017
15
Hepatic paragonimiasis in a 15-month-old girl: a case report. ( 29141594 )
2017
16
Where are we after 60 years of paragonimiasis research? A bibliometric assessment. ( 28603233 )
2017
17
Usefulness and limits of Ziehl-Neelsen staining to detect paragonimiasis in highly endemic tuberculosis areas. ( 29774276 )
2017
18
Case series of paragonimiasis from Nepal. ( 29230303 )
2017
19
Paragonimiasis in Children in Southwest China: A retrospective case reports review from 2005 to 2016. ( 28640131 )
2017
20
A Case of Ectopic Peritoneal Paragonimiasis Mimicking Diverticulitis or Abdominal Abscess. ( 28719956 )
2017
21
Incidence of paragonimiasis in Chongqing China: a 6-year retrospective case review. ( 29113601 )
2017
22
Familial Mediterranean Fever with Rheumatoid Arthritis Complicated by Pulmonary Paragonimiasis. ( 27725555 )
2016
23
Feasibility of laparoscopic major hepatectomy for hepatic paragonimiasis: two case reports. ( 27661049 )
2016
24
Paragonimiasis in tuberculosis patients in Nagaland, India. ( 27667815 )
2016
25
Pleuropulmonary paragonimiasis with migrated lesions cured by multiple therapies. ( 26960636 )
2016
26
Paragonimiasis in a Child from Assam, India. ( 27190807 )
2016
27
Pulmonary Paragonimiasis Mimicking Tuberculous Pleuritis: A Case Report. ( 27082624 )
2016
28
Two cases of paragonimiasis westermani diagnosed after eosinophilic pleural effusion-induced hydropneumothorax. ( 27516883 )
2016
29
Paragonimiasis in tuberculosis patients in Nagaland, India. ( 28156988 )
2016
30
Pulmonary Paragonimiasis: The Detection of a Worm Migration Track as a Diagnostic Clue for Uncertain Eosinophilic Pleural Effusion. ( 26935371 )
2016
31
Demographic characteristic and analysis of pulmonary paragonimiasis in patients attending RIMS, Manipur. ( 27051099 )
2016
32
Paragonimiasis mimicking chest cancer and abdominal wall metastaisis: A case report. ( 27313691 )
2016
33
Cerebral Paragonimiasis Presenting with Sudden Death. ( 27928089 )
2016
34
A tool for mass-screening of paragonimiasis: an enzyme-linked immunosorbent assay with urine samples. ( 27433138 )
2016
35
Characteristic CT and MR imaging findings of cerebral paragonimiasis. ( 27261801 )
2016
36
Declining prevalence of pulmonary paragonimiasis following treatment & community education in a remote tribal population of Arunachal Pradesh, India. ( 26139784 )
2015
37
A rare case of paragonimiasis miyazakii with lung involvement diagnosed 7years after infection: A case report and literature review. ( 25771073 )
2015
38
Paragonimiasis in Japan: a twelve-year retrospective case review (2001-2012). ( 25743009 )
2015
39
Pancreatic paragonimiasis mimics pancreatic cystic-solid tumor - A case report. ( 26256432 )
2015
40
Pulmonary Paragonimiasis Mimicking Tuberculosis. ( 27604443 )
2015
41
[A Case of Intra-abdominal Paragonimiasis Mimicking Metastasis of Lung Cancer Diagnosed by Endoscopic Ultrasound-guided Fine Needle Aspiration]. ( 26194128 )
2015
42
Correction for Diaz, Paragonimiasis Acquired in the United States: Native and Nonnative Species. ( 26354825 )
2015
43
Elevated serum IgG4 levels in two cases of paragonimiasis. ( 26392854 )
2015
44
Pleural fluid characteristics of pleuropulmonary paragonimiasis masquerading as pleural tuberculosis. ( 25589836 )
2015
45
Differential Chest Computed Tomography Findings of Pulmonary Parasite Infestation Between the Paragonimiasis and Nonparagonimiatic Parasite Infestation. ( 26359583 )
2015
46
An unusual case of human paragonimiasis. ( 26265873 )
2015
47
North American paragonimiasis: epidemiology and diagnostic strategies. ( 25835312 )
2015
48
The diagnosis of cutaneous paragonimiasis after the external migration of the parasite from a punch biopsy site. ( 27051740 )
2015
49
Paragonimiasis due to the consumption of wild boar meat in Japan: Contamination levels of lung fluke larvae in muscle samples of wild boars caught in the Kagoshima Prefecture. ( 26370424 )
2015
50
Imaging manifestations and diagnosis of a case of adult cerebral paragonimiasis with the initial symptom of hemorrhagic stroke. ( 26309598 )
2015

Variations for Paragonimiasis

Expression for Paragonimiasis

Search GEO for disease gene expression data for Paragonimiasis.

Pathways for Paragonimiasis

GO Terms for Paragonimiasis

Cellular components related to Paragonimiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 CCL17 CTSF IL13 IL5 RNASE3

Biological processes related to Paragonimiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.5 CCL17 IL13 IL5
2 regulation of signaling receptor activity GO:0010469 9.43 CCL17 IL13 IL5
3 chemokine-mediated signaling pathway GO:0070098 9.16 CCL17 CXCR3
4 positive regulation of B cell proliferation GO:0030890 8.96 IL13 IL5
5 inflammatory response GO:0006954 8.92 CCL17 CXCR3 IL13 IL5

Molecular functions related to Paragonimiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 CCL17 IL13 IL5

Sources for Paragonimiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....